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A", "listPosition" : 4, "share" : 0.0, "first" : false, "last" : true, "corresponding" : false, "familyName" : "Likhachev", "givenName" : "S. A", "authorTyped" : true, "editorTyped" : false, "otherTyped" : false, "type" : { "otype" : "AuthorshipType", "mtid" : 1, "link" : "/api/authorshiptype/1", "label" : "Szerző", "code" : 0, "published" : true, "oldId" : 0, "snippet" : true }, "published" : false, "snippet" : true } ], "title" : "The changes of - cerebrovascular responsiveness in patients with transitory ischemic attacks in the carotid region", "altTitles" : "Изменения - цереброваскулярной реактивности у больных с транзиторными ишемическими атаками в каротидном бассейнеIzmeneniya - tserebrovaskulyarnoi reaktivnosti u bol'nykh s tranzitornymi ishemicheskimi atakami v karotidnom basseine", "identifiers" : [ { "otype" : "PublicationIdentifier", "mtid" : 16032060, "link" : "/api/publicationidentifier/16032060", "label" : "WoS: RSCI:10438946", "source" : { "otype" : "PlainSource", "mtid" : 1, "link" : "/api/publicationsource/1", "label" : "WoS", "type" : { "otype" : "PublicationSourceType", "mtid" : 10003, "link" : "/api/publicationsourcetype/10003", "label" : "Indexelő adatbázis", "mayHaveOa" : false, "published" : true, "snippet" : true }, "name" : "WoS", "nameEng" : "WoS", "linkPattern" : "https://www.webofscience.com/wos/woscc/full-record/@@@", "publiclyVisible" : true, "published" : true, "oldId" : 1, "snippet" : true }, "idValue" : "RSCI:10438946", "realUrl" : "https://www.webofscience.com/wos/woscc/full-record/RSCI:10438946", "published" : false, "snippet" : true } ], "journal" : { "otype" : "Journal", "mtid" : 10062819, "link" : "/api/journal/10062819", "label" : "NEVROLOGICHESKII ZHURNAL 1560-9545 2413-0699", "pIssn" : "1560-9545", "eIssn" : "2413-0699", "reviewType" : "REVIEWED", "noIF" : false, "sciIndexed" : false, "scopusIndexed" : true, "lang" : "FOREIGN", "hungarian" : false, "published" : true, "oldId" : 10062819, "snippet" : true }, "volume" : "13", "issue" : "3", "firstPage" : "21", "lastPage" : "25", "firstPageOrInternalIdForSort" : "21", "pageLength" : 5, "publishedYear" : 2008, "abstractText" : "С целью объективизации изменений цереброваскулярной реактивности (ЦБР) проведено комплексное обследование 40 больных в возрасте 43-67 лет с транзиторными ишемическими атаками (ТИА) в каротидном бассейне (КБ). Контрольная группа включала 25 практически здоровых добровольцев сопоставимого возраста. Для исследования ЦБР использованы проба с произвольной задержкой дыхания и вычислением индекса задержки дыхания и тест с гипервентиляцией и задержкой дыхания. У больных с ТИА в КБ выявлены различные по степени выраженности и продолжительности изменения ЦБР, находящиеся в определенной зависимости от ведущего патогенетического механизма заболевания. У больных с ТИА в КБ на фоне изолированной артериальной гипертензии выявлены два основных варианта динамики изменений ЦБР. У 58,3% пациентов более выраженным изменениям ЦБР соответствовало более тяжелое течение заболевания, характеризующееся большей длительностью приступов дисгемии и степенью выраженности явлений церебральной микроангиопатии. У больных с ТИА на фоне гемодинамически значимого поражения церебральных артерий наиболее выраженное снижение резервов регуляции сосудистого тонуса при отсутствии достоверной положительной динамики в процессе лечения наблюдалось на стороне пораженного артериального бассейна. У 37,5% больных с кардиоэмболическим генозом ТИА в особенности на 2-4-й день после перенесенной атаки выявлены выраженные нарушения ЦБР, ассоциировавшиеся с более тяжелым течением, а иногда с неблагоприятным исходом заболевания.The article reviews the results of a complex investigation aimed at the objectivization of the changes of cerebrovascular responsiveness (CVR). Forty (40) patients aged 43 - 67years old with transitory ischemic attacks \\(TIA) in the carotid region (CR) were enrolled in the study. The control group comprised 25 age-matched healthy volunteers. For the assessment of CVR the test with voluntary breath-holding and calculation of breath-holding index was carried out. Bеsides, the test with hyperventilation and breath-holding was performed. In patients with TIA in CR the changes of CVR characterized by different degrees and duration were detected. Such changes depended on the principal patho-genetic mechanism. In subjects with TIA in CR associated with isolated arterial hypertension two main types of the time-course changes of CVR were detected. In 58.3% of the patients more prominent changes correlated with more severe course of the disease characterized by more prolonged attacks ofdyshemia and more intense neuroimaging signs of cerebral microangiopathy. In subjects with TIA associated with hemodynamically significant cerebral arterial lesions the most prominent decrease of CVR was detected on the side of the affected arterial region that was associated with the lack of significant positive therapeutic effect. In 37.5% patients with TIA of cardioembolic origin especially on the 2 - 4th day since the attack marked pathological changes of CVR were revealed. Such changes were associated with more severe course of the disease and in some cases with unfavorable outcome.", "keywords" : [ { "otype" : "Keyword", "mtid" : 1246598, "link" : "/api/keyword/1246598", "label" : "Cerebrovascular responsiveness", "published" : true, "oldId" : 1246598, "snippet" : true }, { "otype" : "Keyword", "mtid" : 1794214, "link" : "/api/keyword/1794214", "label" : "цереброваскулярная реактивность", "published" : true, "snippet" : true }, { "otype" : "Keyword", "mtid" : 1794215, "link" : "/api/keyword/1794215", "label" : "транзиторные ишемические атаки", "published" : true, "snippet" : true }, { "otype" : "Keyword", "mtid" : 1794216, "link" : "/api/keyword/1794216", "label" : "каротидный бассейн", "published" : true, "snippet" : true }, { "otype" : "Keyword", "mtid" : 1794217, "link" : "/api/keyword/1794217", "label" : "transitory ischemic attack", "published" : true, "snippet" : true }, { "otype" : "Keyword", "mtid" : 1794218, "link" : "/api/keyword/1794218", "label" : "carotid region", "published" : true, "snippet" : true } ], "digital" : null, "printed" : null, "sourceYear" : 2019, "foreignEdition" : true, "foreignLanguage" : true, "fullPublication" : true, "conferencePublication" : false, "nationalOrigin" : null, "missingAuthor" : false, "oaType" : "NONE", "oaCheckDate" : "2024-03-13", "oaFree" : false, "citationCount" : 0, "citationCountUnpublished" : 0, "citationCountWoOther" : 0, "independentCitCountWoOther" : 0, "doiCitationCount" : 0, "wosCitationCount" : 0, "scopusCitationCount" : 0, "independentCitationCount" : 0, "unhandledCitationCount" : 0, "citingPubCount" : 0, "independentCitingPubCount" : 0, "unhandledCitingPubCount" : 0, "citedPubCount" : 2, "citedCount" : 2, "hasCitationDuplums" : false, "userChangeableUntil" : "2020-08-29T20:22:41.014+0000", "directInstitutesForSort" : "", "ownerAuthorCount" : 7, "ownerInstituteCount" : 29, "directInstituteCount" : 0, "authorCount" : 4, "contributorCount" : 0, "hasQualityFactor" : false, "link" : "/api/publication/30879827", "label" : "Белявский Н.Н. et al. 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