Microbial biofilm and quorum sensing are two intertwined traits that have been used
by microorganisms for their survival and improved virulence. They have been implicated
as the cause of severe infections in humans as their incidence makes it difficult
to treat common infections and the possibility of recurrent infections is high. Microbial
biofilm and quorum sensing have also been increasingly implicated in the food processing
and the medical industry where they have caused food and surface contamination. As
a result of emerging resistance, conventional control methods are fast becoming ineffective.
In this review, we highlight the potential of South African plants as sources of antibiofilm
and quorum quenching bioactive secondary metabolites. The review emphasizes antimicrobial
studies of medicinal plants with regard to foodborne pathogens and the relevant public
health importance. Also discussed is the role of quorum sensing and biofilm formation
in antimicrobial resistance. A total of 46 plant species belonging to 27 families
and 31 isolated bioactive compounds were documented to have antibiofilm and quorum
quenching capacity against foodborne pathogens. This review seeks to summarize present
knowledge on South African medicinal plants with antibiofilm and quorum quenching
potential. It also provides support for continuing investigations on South African
medicinal plants with previously reported good to excellent antimicrobial activities.
(C) 2019 SAAB. Published by Elsevier B.V. All rights reserved.