https://m2.mtmt.hu/ hun 2026-04-30 11:05 JournalArticle 30808466 VALIDATED true 0 false 2025-12-28T15:36:42.195+0000 2024-09-04T09:53:41.242+0000 2019-09-19T11:17:37.829+0000 true 10067746 Király Magdolna /api/admin/10067746 Admin Király Magdolna (DE admin 4) true 2025-03-27T17:16:29.393+0000 2025-03-27T17:16:29.393+0000 2019-12-04T14:58:27.370+0000 true 10014568 Vándor Andrea /api/admin/10014568 Admin Vándor Andrea (VA, admin) true 10014568 2021-10-21T06:09:06.149+0000 true 10080085 Fölkerné Csernyik Rita /api/admin/10080085 Admin Fölkerné Csernyik Rita (MTMT ellenőrzés admin5) true true false true 24 24 /api/publicationtype/24 PublicationType Folyóiratcikk 1 true 24 JournalArticle true 10000059 Article true 24 24 /api/publicationtype/24 PublicationType Folyóiratcikk 1 true 24 JournalArticle /api/subtype/10000059 Szakcikk SubType Szakcikk (Folyóiratcikk) 101 true 10000059 true 1 /api/category/1 Category Tudományos true 1 Csikai, E. true true /api/journal/3178 REVIEWED MEDICINE 0025-7974 1536-5964 true false 3178 false 3178 true 0025-7974 1536-5964 Journal FOREIGN 98 34 e16966 e16966 9 2019 The importance of optimal blood pressure control for preventing or reducing the impairment of vascular and cognitive functions is well known. However, the reversibility of early alterations in vascular and cognitive functions through antihypertensive agents is under-investigated. In this study, we evaluated the influence of 3 months of angiotensin-converting enzyme (ACE) inhibition treatment on the morphological and functional arterial wall and cognitive performance changes in 30 newly diagnosed primary hypertensive patients.Common carotid intima-media thickness (IMT) and brachial artery flow-mediated dilatation (FMD) were detected by ultrasonography. Arterial stiffness indicated by augmentation index (AIx) and pulse wave velocity (PWV) was assessed by arteriography. Cognitive functions were assessed by neuropsychological examination.The executive function overall score was significantly higher at 3-month follow-up than at baseline (median, 0.233 (IQR, 0.447) vs -0.038 (0.936); P = .001). Three-month ACE inhibition did not produce significant improvement in IMT, FMD, AIx and PWV values. Significant negative associations were revealed between IMT and complex attention (r = -0.598, P = .0008), executive function (r = -0.617, P = .0005), and immediate memory (r = -0.420, P = .026) overall scores at follow-up. AIx had significant negative correlations with complex attention (r = -0.568, P = .001), executive function (r = -0.374, P = .046), and immediate memory (r = -0.507, P = .005). PWV correlated significantly and negatively with complex attention (r = -0.490, P = .007).Timely and effective antihypertensive therapy with ACE inhibitors has significant beneficial effects on cognitive performance in as few as 3 months. Early ACE inhibition may have an important role in the reversal of initial impairments of cognitive function associated with hypertension-induced vascular alterations. 2019 true true true false true false GOLD 2025-12-28 true https://doi.org/10.1097/MD.0000000000016966 3 0 3 2 1 3 2 2 3 3 3 2 2 2 1 0 3 2 3 2 0 35 35 Folyóiratcikk Journal Article 24 3 Könyvrészlet Chapter in Book 25 0 Könyv Book 23 0 Egyéb konferenciaközlemény Conference paper 31 0 Egyéb konferenciakötet Conference proceedings 32 0 Oltalmi formák Protection forms 26 0 Disszertáció Thesis 28 0 Egyéb Miscellaneous 29 0 Alkotás Achievement 22 0 Kutatási adat Research data 33 0 Folyóiratcikk Journal Article 24 0 0 0 Könyvrészlet Chapter in Book 25 0 0 0 Könyv Book 23 0 0 0 Egyéb konferenciaközlemény Conference paper 31 0 0 0 Egyéb konferenciakötet Conference proceedings 32 0 0 0 Oltalmi formák Protection forms 26 0 0 0 Disszertáció Thesis 28 0 0 0 Egyéb Miscellaneous 29 0 0 0 Alkotás Achievement 22 0 0 0 Kutatási adat Research data 33 0 0 0 2020 0 1 1 1 1 2021 0 1 1 1 1 2022 0 1 0 1 0 Q2 false 10010245,10059586 false false false 2019-09-18T11:18:47.341+0000 Klinikai és Egészségpszichológiai Tanszék (DE / NK / MagtudI); MTA-DE Cerebrovascularis és Neurodegeneratív Ku... (DE / ÁOK); Neurológiai Tanszék (DE / ÁOK) 7 27 3 10 0 true Language 10002 /api/language/10002 Angol Angol English true 2 true PersonAuthorship 87999377 /api/authorship/87999377 Csikai, E. [Csikai, Enikő (Egészségpszichológus), szerző] Klinikai és Egészségpszichológiai Tanszék (DE / NK / MagtudI) 1 0.1 true false false Author 10067241 /api/author/10067241 Csikai Enikő (Egészségpszichológus) Csikai Enikő true true Csikai E. true false false AuthorshipType 1 /api/authorshiptype/1 Szerző 0 true 0 true false true PersonAuthorship 87999378 /api/authorship/87999378 Andrejkovics, M. [Andrejkovics, Mónika (Klinikai pszichol...), szerző] 2 0.1 false false false Author 10010245 /api/author/10010245 Andrejkovics Mónika (Klinikai pszichológia) Andrejkovics Mónika true 10010245 true Andrejkovics M. true false false AuthorshipType 1 /api/authorshiptype/1 Szerző 0 true 0 true false true PersonAuthorship 87999379 /api/authorship/87999379 Balajthy-Hidegh, B. 3 0.1 false false false Balajthy-Hidegh B. true false false AuthorshipType 1 /api/authorshiptype/1 Szerző 0 true 0 true false true PersonAuthorship 87999380 /api/authorship/87999380 Hofgárt, G. [Hofgárt, Gergely (neurológia), szerző] Neurológiai Tanszék (DE / ÁOK) 4 0.1 false false false Author 10051211 /api/author/10051211 Hofgárt Gergely (neurológia) Hofgárt Gergely true 10051211 true Hofgárt G. true false false AuthorshipType 1 /api/authorshiptype/1 Szerző 0 true 0 true false true PersonAuthorship 87999381 /api/authorship/87999381 Kardos, L. 5 0.1 false false false Kardos L. true false false AuthorshipType 1 /api/authorshiptype/1 Szerző 0 true 0 true false true PersonAuthorship 87999382 /api/authorship/87999382 Diószegi, Á. 6 0.1 false false false Diószegi Á. true false false AuthorshipType 1 /api/authorshiptype/1 Szerző 0 true 0 true false true PersonAuthorship 87999383 /api/authorship/87999383 Rostás, R. [Rostás, Róbert (neurológia, radio...), szerző] 7 0.1 false false false Author 10096525 /api/author/10096525 Rostás Róbert (neurológia, radiológia) Rostás Róbert true true Rostás R. true false false AuthorshipType 1 /api/authorshiptype/1 Szerző 0 true 0 true false true PersonAuthorship 87999384 /api/authorship/87999384 Czuriga-Kovács, K.R. [Kovács, Katalin Réka (Neurológia), szerző] Neurológiai Tanszék (DE / ÁOK) 8 0.1 false false false Author 10038990 /api/author/10038990 Kovács Katalin Réka (Neurológia) Kovács Katalin Réka true 10038990 true Czuriga-Kovács K.R. true false false AuthorshipType 1 /api/authorshiptype/1 Szerző 0 true 0 true false true PersonAuthorship 87999385 /api/authorship/87999385 Csongrádi, É. [Csongrádi, Éva (belgyógyászat), szerző] MTA-DE Cerebrovascularis és Neurodegeneratív Ku... (DE / ÁOK) 9 0.1 false false false Author 10059586 /api/author/10059586 Csongrádi Éva (belgyógyászat) Csongrádi Éva true 10059586 true Csongrádi É. true false false AuthorshipType 1 /api/authorshiptype/1 Szerző 0 true 0 true false true PersonAuthorship 87999386 /api/authorship/87999386 Csiba, L. ✉ [Csiba, László (Neurológia), szerző] Neurológiai Tanszék (DE / ÁOK); MTA-DE Cerebrovascularis és Neurodegeneratív Ku... (DE / ÁOK) 10 0.1 false true true Author 10000492 /api/author/10000492 Csiba László (Neurológia) Csiba László true 10000492 true Csiba L. true false false AuthorshipType 1 /api/authorshiptype/1 Szerző 0 true 0 true false true PublicationIdentifier 15908595 /api/publicationidentifier/15908595 DOI: 10.1097/MD.0000000000016966 PlainSource 6 /api/publicationsource/6 DOI PublicationSourceType 10001 /api/publicationsourcetype/10001 DOI true true true DOI DOI https://doi.org/@@@ true true 6 true GOLD true IDENTICAL 10.1097/MD.0000000000016966 https://doi.org/10.1097/MD.0000000000016966 false true PublicationIdentifier 15969891 /api/publicationidentifier/15969891 WoS: 000486383000067 PlainSource 1 /api/publicationsource/1 WoS PublicationSourceType 10003 /api/publicationsourcetype/10003 Indexelő adatbázis false true true WoS WoS https://www.webofscience.com/wos/woscc/full-record/@@@ true true 1 true IDENTICAL 000486383000067 https://www.webofscience.com/wos/woscc/full-record/000486383000067 false true PublicationIdentifier 16177024 /api/publicationidentifier/16177024 REAL: 104114 SwordSource 36 /api/publicationsource/36 REAL PublicationSourceType 10007 /api/publicationsourcetype/10007 Repozitórium true true true REAL REAL http://real.mtak.hu/@@@ true true 36 true GREEN true 104114 http://real.mtak.hu/104114 true true PublicationIdentifier 25039145 /api/publicationidentifier/25039145 DEA: 278743 PlainSource 38 /api/publicationsource/38 DEA PublicationSourceType 10007 /api/publicationsourcetype/10007 Repozitórium true true true DEA http://hdl.handle.net/2437/@@@ true true 38 true IDENTICAL 278743 http://hdl.handle.net/2437/278743 false true PublicationIdentifier 15908594 /api/publicationidentifier/15908594 Scopus: 85071502993 PlainSource 3 /api/publicationsource/3 Scopus PublicationSourceType 10003 /api/publicationsourcetype/10003 Indexelő adatbázis false true true Scopus Scopus http://www.scopus.com/record/display.url?origin=inward&eid=2-s2.0-@@@ true true 3 true IDENTICAL 85071502993 http://www.scopus.com/record/display.url?origin=inward&eid=2-s2.0-85071502993 false true PublicationIdentifier 18362905 /api/publicationidentifier/18362905 Egyéb URL: http://Insights.ovid.com/crossref?an=00005792-201908230-00068 PlainSource 40 /api/publicationsource/40 Egyéb URL PublicationSourceType 10006 /api/publicationsourcetype/10006 Link true true true Egyéb URL Other URL @@@ true true 40 true NONE IDENTICAL http://Insights.ovid.com/crossref?an=00005792-201908230-00068 http://Insights.ovid.com/crossref?an=00005792-201908230-00068 false true Keyword 11 /api/keyword/11 Blood Pressure true 11 true Keyword 11 /api/keyword/11 Blood Pressure true 11 true Keyword 21 /api/keyword/21 Follow-Up Studies true 21 true Keyword 52 /api/keyword/52 Adult true 52 true Keyword 52 /api/keyword/52 Adult true 52 true Keyword 56 /api/keyword/56 Female true 56 true Keyword 56 /api/keyword/56 Female true 56 true Keyword 61 /api/keyword/61 Middle Aged true 61 true Keyword 61 /api/keyword/61 Middle Aged true 61 true Keyword 62 /api/keyword/62 Male true 62 true Keyword 62 /api/keyword/62 Male true 62 true Keyword 65 /api/keyword/65 Humans true 65 true Keyword 1850 /api/keyword/1850 VASODILATATION true 1850 true Keyword 3122 /api/keyword/3122 human true 3122 true Keyword 4037 /api/keyword/4037 Prospective Studies true 4037 true Keyword 4807 /api/keyword/4807 HYPERTENSION true 4807 true Keyword 4807 /api/keyword/4807 HYPERTENSION true 4807 true Keyword 5905 /api/keyword/5905 drug effect true 5905 true Keyword 5962 /api/keyword/5962 cognition true 5962 true Keyword 5962 /api/keyword/5962 cognition true 5962 true Keyword 10463 /api/keyword/10463 Vasodilation true 10463 true Keyword 10592 /api/keyword/10592 Diagnostic Imaging true 10592 true Keyword 14096 /api/keyword/14096 dipeptidyl carboxypeptidase inhibitor true 14096 true Keyword 14216 /api/keyword/14216 prospective study true 14216 true Keyword 17613 /api/keyword/17613 carotid arteries true 17613 true Keyword 19888 /api/keyword/19888 carotid artery true 19888 true Keyword 20203 /api/keyword/20203 follow up true 20203 true Keyword 1017307 /api/keyword/1017307 brachial artery true 1017307 true Keyword 1017307 /api/keyword/1017307 brachial artery true 1017307 true Keyword 1020073 /api/keyword/1020073 Angiotensin-Converting Enzyme Inhibitors true 1020073 true Keyword 1033774 /api/keyword/1033774 arterial stiffness true 1033774 true Keyword 1036308 /api/keyword/1036308 arterial wall thickness true 1036308 true Keyword 1036321 /api/keyword/1036321 Carotid intima-media thickness true 1036321 true Keyword 1501019 /api/keyword/1501019 vascular stiffness true true SjrRating 10993423 /api/sjrrating/10993423 sjr:Q2 (2019) Scopus - 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Influence of angiotensin-converting enzyme inhibition on reversibility of alterations in arterial wall and cognitive performance associated with early hypertension: A follow-up study. (2019) MEDICINE 0025-7974 1536-5964 98 34<div class="JournalArticle Publication long-list"> <div class="authors"> <img title="Forrásközlemény" style="float: left" src="/frontend/resources/grid/publication-core-icon.png"> <img title="Idézőközlemény" style="float: left" src="/frontend/resources/grid/publication-citation-icon.png"> <div class="autype autype0"> <span class="author-name" mtid="10067241"><a href="/gui2/?type=authors&mode=browse&sel=10067241" target="_blank">Csikai E. (<span class="authorship-author-name">Csikai Enikő</span> <span class="authorAux-mtmt"> Egészségpszichológus</span>) </a> </span> <span class="author-affil"><span title="Debreceni Egyetem">DE</span>/<span title="Népegészségügyi Kar">NK</span>/<span title="Magatartástudományi Intézet">MagtudI</span>/Klinikai és Egészségpszichológiai Tanszék</span> ;&nbsp;&nbsp;&nbsp; <span class="author-name" mtid="10010245"><a href="/gui2/?type=authors&mode=browse&sel=10010245" target="_blank">Andrejkovics M. (<span class="authorship-author-name">Andrejkovics Mónika</span> <span class="authorAux-mtmt"> Klinikai pszichológia</span>) </a> </span> ;&nbsp;&nbsp;&nbsp; <span class="author-name" >Balajthy-Hidegh B. </span> ;&nbsp;&nbsp;&nbsp; <span class="author-name" mtid="10051211"><a href="/gui2/?type=authors&mode=browse&sel=10051211" target="_blank">Hofgárt G. (<span class="authorship-author-name">Hofgárt Gergely</span> <span class="authorAux-mtmt"> neurológia</span>) </a> </span> <span class="author-affil"><span title="Debreceni Egyetem">DE</span>/<span title="Általános Orvostudományi Kar">ÁOK</span>/Neurológiai Tanszék</span> ;&nbsp;&nbsp;&nbsp; <span class="author-name" >Kardos L. </span> ;&nbsp;&nbsp;&nbsp; <span class="author-name" >Diószegi Á. </span> ;&nbsp;&nbsp;&nbsp; <span class="author-name" mtid="10096525"><a href="/gui2/?type=authors&mode=browse&sel=10096525" target="_blank">Rostás R. (<span class="authorship-author-name">Rostás Róbert</span> <span class="authorAux-mtmt"> neurológia, radiológia</span>) </a> </span> ;&nbsp;&nbsp;&nbsp; <span class="author-name" mtid="10038990"><a href="/gui2/?type=authors&mode=browse&sel=10038990" target="_blank">Czuriga-Kovács K.R. (<span class="authorship-author-name">Kovács Katalin Réka</span> <span class="authorAux-mtmt"> Neurológia</span>) </a> </span> <span class="author-affil"><span title="Debreceni Egyetem">DE</span>/<span title="Általános Orvostudományi Kar">ÁOK</span>/Neurológiai Tanszék</span> ;&nbsp;&nbsp;&nbsp; <span class="author-name" mtid="10059586"><a href="/gui2/?type=authors&mode=browse&sel=10059586" target="_blank">Csongrádi É. (<span class="authorship-author-name">Csongrádi Éva</span> <span class="authorAux-mtmt"> belgyógyászat</span>) </a> </span> <span class="author-affil"><span title="Debreceni Egyetem">DE</span>/<span title="Általános Orvostudományi Kar">ÁOK</span>/MTA-DE Cerebrovascularis és Neurodegeneratív Kutatócsoport</span> ;&nbsp;&nbsp;&nbsp; <span class="author-name" mtid="10000492"><a href="/gui2/?type=authors&mode=browse&sel=10000492" target="_blank">Csiba L. ✉ (<span class="authorship-author-name">Csiba László</span> <span class="authorAux-mtmt"> Neurológia</span>) </a> </span> <span class="author-affil"><span title="Debreceni Egyetem">DE</span>/<span title="Általános Orvostudományi Kar">ÁOK</span>/Neurológiai Tanszék; <span title="Debreceni Egyetem">DE</span>/<span title="Általános Orvostudományi Kar">ÁOK</span>/MTA-DE Cerebrovascularis és Neurodegeneratív Kutatócsoport</span> </div> </div> <div class="title"><a href="/gui2/?mode=browse&params=publication;30808466" target="_blank">Influence of angiotensin-converting enzyme inhibition on reversibility of alterations in arterial wall and cognitive performance associated with early hypertension: A follow-up study</a></div> <div> <span class="journal-title">MEDICINE</span> <span class="journal-issn">(<a target="_blank" href="https://portal.issn.org/resource/ISSN/0025-7974">0025-7974</a> <a target="_blank" href="https://portal.issn.org/resource/ISSN/1536-5964">1536-5964</a>)</span>: <span class="journal-volume">98</span> <span class="journal-issue">34</span> <span class="page"> Paper e16966. 9 p. </span> <span class="year">(2019)</span> </div> <div class="pub-footer"> <span class="language" xmlns="http://www.w3.org/1999/html">Nyelv: Angol | </span> <span class="identifiers"> <span class="id identifier oa_GOLD" title=" Gold "> <a style="color:blue" title="10.1097/MD.0000000000016966" target="_blank" href="https://doi.org/10.1097/MD.0000000000016966"> DOI </a> </span> <span class="id identifier oa_none" title="none"> <a style="color:blue" title="000486383000067" target="_blank" href="https://www.webofscience.com/wos/woscc/full-record/000486383000067"> WoS </a> </span> <span class="id identifier oa_GREEN" title=" Green "> <a style="color:black" title="104114" target="_blank" href="http://real.mtak.hu/104114"> REAL </a> </span> <span class="id identifier oa_none" title="none"> <a style="color:blue" title="278743" target="_blank" href="http://hdl.handle.net/2437/278743"> DEA </a> </span> <span class="id identifier oa_none" title="none"> <a style="color:blue" title="85071502993" target="_blank" href="http://www.scopus.com/record/display.url?origin=inward&eid=2-s2.0-85071502993"> Scopus </a> </span> <span class="id identifier oa_NONE" title=" Nincs "> <a style="color:blue" title="http://Insights.ovid.com/crossref?an=00005792-201908230-00068" target="_blank" href="http://Insights.ovid.com/crossref?an=00005792-201908230-00068"> Egyéb URL </a> </span> </span> <OnlyViewableByAuthor><div class="ratings"> <div class="journal-subject">Folyóirat szakterülete: Scopus - Medicine (miscellaneous)&nbsp;&nbsp;&nbsp;SJR indikátor:&nbsp;Q2</div> </div></OnlyViewableByAuthor> <div class="publication-citation" style="margin-left: 0.5cm;"> <span title="Nyilvános idézőközlemények összesen, említések nélkül" class="citingPub-count">Nyilvános idéző összesen: 3</span> | Független: 2 | Függő: 1 | Nem jelölt: 0 | WoS jelölt: 2 | Scopus jelölt:&nbsp;3 | WoS/Scopus jelölt:&nbsp;3 | DOI jelölt:&nbsp;2 </div> <div class="publication-citation"> <a target="_blank" href="/api/publication?cond=citations.related;eq;30808466&sort=publishedYear,desc&sort=title"> Idézett közlemények száma: 35 </a> </div> <div class="mtid"><span class="long-pub-mtid">Közlemény: 30808466</span> | <span class="status-data status-VALIDATED"> Egyeztetett </span> Forrás Idéző | <span class="type-subtype">Folyóiratcikk ( Szakcikk ) </span> | <span class="pub-category">Tudományos</span> | <span class="publication-sourceOfData">Scopus (scopus.ris, 2019-09-19)</span> </div> <div class="lastModified">Utolsó módosítás: 2024.09.04. 11:53 Rostás Róbert (neurológia, radiológia) </div> </div></div>