Endocannabinoid Signaling Mediates Local Dendritic Coordination between Excitatory and Inhibitory Synapses

https://m2.mtmt.hu/ eng 2026-09-23 01:42 JournalArticle 30651814 VALIDATED true Department of Biology, Science for Life, Utrecht University, Utrecht, 3584CH, Netherlands Laboratory of 3D Functional Network and Dendritic Imaging, Institute of Experimental Medicine, Hungarian Academy of Sciences, Budapest, 1083, Hungary Faculty of Information Technology, Pázmány Péter Catholic University, Budapest, 1083, Hungary Export Date: 14 November 2019 Correspondence Address: Wierenga, C.J.; Department of Biology, Science for Life, Utrecht UniversityNetherlands; email: c.j.wierenga@uu.nl Chemicals/CAS: glutamic acid, 11070-68-1, 138-15-8, 56-86-0, 6899-05-4 Funding details: Foundation for Fundamental Research on Matter, 15PR3178-1, 16NEPH05, 34 FP7/2007 Funding details: 016.126.361 Funding details: NVKP16-1-2016-0043, ERCVisionby3DSTIM, GINOP2.1.1-15-2016-00979, KFI16-1-2016-0177 Funding details: Research Executive Agency, 289581 Funding details: Foundation for Fundamental Research on Matter Funding text 1: The authors thank René van Dorland for excellent technical support. This research was supported by the Netherlands Organization for Scientific Research , as part of the VIDI program ( #016.126.361; to C.J.W. ); the research program of the Foundation for Fundamental Research on Matter (FOM) ( #15PR3178-1 and #16NEPH05 to C.J.W.) and the VICI program (to C.C.H.); by the program 34 FP7/2007-2013/ under Research Executive Agency (REA) grant agreement 289581 (to C.P.F.); and by ERCVisionby3DSTIM , KFI16-1-2016-0177 , NVKP16-1-2016-0043 , and GINOP2.1.1-15-2016-00979 (to B.R.). Department of Biology, Science for Life, Utrecht University, Utrecht, 3584CH, Netherlands Laboratory of 3D Functional Network and Dendritic Imaging, Institute of Experimental Medicine, Hungarian Academy of Sciences, Budapest, 1083, Hungary Faculty of Information Technology, Pázmány Péter Catholic University, Budapest, 1083, Hungary Export Date: 15 November 2019 Correspondence Address: Wierenga, C.J.; Department of Biology, Science for Life, Utrecht UniversityNetherlands; email: c.j.wierenga@uu.nl Chemicals/CAS: glutamic acid, 11070-68-1, 138-15-8, 56-86-0, 6899-05-4 Funding details: Foundation for Fundamental Research on Matter, 15PR3178-1, 16NEPH05, 34 FP7/2007 Funding details: 016.126.361 Funding details: NVKP16-1-2016-0043, ERCVisionby3DSTIM, GINOP2.1.1-15-2016-00979, KFI16-1-2016-0177 Funding details: Research Executive Agency, 289581 Funding details: Foundation for Fundamental Research on Matter Funding text 1: The authors thank René van Dorland for excellent technical support. This research was supported by the Netherlands Organization for Scientific Research , as part of the VIDI program ( #016.126.361; to C.J.W. ); the research program of the Foundation for Fundamental Research on Matter (FOM) ( #15PR3178-1 and #16NEPH05 to C.J.W.) and the VICI program (to C.C.H.); by the program 34 FP7/2007-2013/ under Research Executive Agency (REA) grant agreement 289581 (to C.P.F.); and by ERCVisionby3DSTIM , KFI16-1-2016-0177 , NVKP16-1-2016-0043 , and GINOP2.1.1-15-2016-00979 (to B.R.). Department of Biology, Science for Life, Utrecht University, Utrecht, 3584CH, Netherlands Laboratory of 3D Functional Network and Dendritic Imaging, Institute of Experimental Medicine, Hungarian Academy of Sciences, Budapest, 1083, Hungary Faculty of Information Technology, Pázmány Péter Catholic University, Budapest, 1083, Hungary Cited By :1 Export Date: 22 April 2020 Correspondence Address: Wierenga, C.J.; Department of Biology, Science for Life, Utrecht UniversityNetherlands; email: c.j.wierenga@uu.nl Chemicals/CAS: glutamic acid, 11070-68-1, 138-15-8, 56-86-0, 6899-05-4 Funding details: Foundation for Fundamental Research on Matter, FOM, NVKP16-1-2016-0043, 15PR3178-1, 16NEPH05, GINOP2.1.1-15-2016-00979, KFI16-1-2016-0177, 289581 Funding details: 016.126.361 Funding details: Foundation for Fundamental Research on Matter, FOM Funding text 1: The authors thank René van Dorland for excellent technical support. This research was supported by the Netherlands Organization for Scientific Research , as part of the VIDI program ( #016.126.361; to C.J.W. ); the research program of the Foundation for Fundamental Research on Matter (FOM) ( #15PR3178-1 and #16NEPH05 to C.J.W.) and the VICI program (to C.C.H.); by the program 34 FP7/2007-2013/ under Research Executive Agency (REA) grant agreement 289581 (to C.P.F.); and by ERCVisionby3DSTIM , KFI16-1-2016-0177 , NVKP16-1-2016-0043 , and GINOP2.1.1-15-2016-00979 (to B.R.). Department of Biology, Science for Life, Utrecht University, Utrecht, 3584CH, Netherlands Laboratory of 3D Functional Network and Dendritic Imaging, Institute of Experimental Medicine, Hungarian Academy of Sciences, Budapest, 1083, Hungary Faculty of Information Technology, Pázmány Péter Catholic University, Budapest, 1083, Hungary Cited By :1 Export Date: 24 April 2020 Correspondence Address: Wierenga, C.J.; Department of Biology, Science for Life, Utrecht UniversityNetherlands; email: c.j.wierenga@uu.nl Chemicals/CAS: glutamic acid, 11070-68-1, 138-15-8, 56-86-0, 6899-05-4 Funding details: Foundation for Fundamental Research on Matter, FOM, NVKP16-1-2016-0043, 15PR3178-1, 16NEPH05, GINOP2.1.1-15-2016-00979, KFI16-1-2016-0177, 289581 Funding details: 016.126.361 Funding details: Foundation for Fundamental Research on Matter, FOM Funding text 1: The authors thank René van Dorland for excellent technical support. This research was supported by the Netherlands Organization for Scientific Research , as part of the VIDI program ( #016.126.361; to C.J.W. ); the research program of the Foundation for Fundamental Research on Matter (FOM) ( #15PR3178-1 and #16NEPH05 to C.J.W.) and the VICI program (to C.C.H.); by the program 34 FP7/2007-2013/ under Research Executive Agency (REA) grant agreement 289581 (to C.P.F.); and by ERCVisionby3DSTIM , KFI16-1-2016-0177 , NVKP16-1-2016-0043 , and GINOP2.1.1-15-2016-00979 (to B.R.). Department of Biology, Science for Life, Utrecht University, Utrecht, 3584CH, Netherlands Laboratory of 3D Functional Network and Dendritic Imaging, Institute of Experimental Medicine, Hungarian Academy of Sciences, Budapest, 1083, Hungary Faculty of Information Technology, Pázmány Péter Catholic University, Budapest, 1083, Hungary Cited By :1 Export Date: 13 May 2020 Correspondence Address: Wierenga, C.J.; Department of Biology, Science for Life, Utrecht UniversityNetherlands; email: c.j.wierenga@uu.nl Chemicals/CAS: glutamic acid, 11070-68-1, 138-15-8, 56-86-0, 6899-05-4 Funding details: Foundation for Fundamental Research on Matter, FOM, NVKP16-1-2016-0043, 15PR3178-1, 16NEPH05, GINOP2.1.1-15-2016-00979, KFI16-1-2016-0177, 289581 Funding details: 016.126.361 Funding details: Foundation for Fundamental Research on Matter, FOM Funding text 1: The authors thank René van Dorland for excellent technical support. This research was supported by the Netherlands Organization for Scientific Research , as part of the VIDI program ( #016.126.361; to C.J.W. ); the research program of the Foundation for Fundamental Research on Matter (FOM) ( #15PR3178-1 and #16NEPH05 to C.J.W.) and the VICI program (to C.C.H.); by the program 34 FP7/2007-2013/ under Research Executive Agency (REA) grant agreement 289581 (to C.P.F.); and by ERCVisionby3DSTIM , KFI16-1-2016-0177 , NVKP16-1-2016-0043 , and GINOP2.1.1-15-2016-00979 (to B.R.). Department of Biology, Science for Life, Utrecht University, Utrecht, 3584CH, Netherlands Laboratory of 3D Functional Network and Dendritic Imaging, Institute of Experimental Medicine, Hungarian Academy of Sciences, Budapest, 1083, Hungary Faculty of Information Technology, Pázmány Péter Catholic University, Budapest, 1083, Hungary Cited By :1 Export Date: 14 May 2020 Correspondence Address: Wierenga, C.J.; Department of Biology, Science for Life, Utrecht UniversityNetherlands; email: c.j.wierenga@uu.nl Chemicals/CAS: glutamic acid, 11070-68-1, 138-15-8, 56-86-0, 6899-05-4 Funding details: Foundation for Fundamental Research on Matter, FOM, NVKP16-1-2016-0043, 15PR3178-1, 16NEPH05, GINOP2.1.1-15-2016-00979, KFI16-1-2016-0177, 289581 Funding details: 016.126.361 Funding details: Foundation for Fundamental Research on Matter, FOM Funding text 1: The authors thank René van Dorland for excellent technical support. This research was supported by the Netherlands Organization for Scientific Research , as part of the VIDI program ( #016.126.361; to C.J.W. ); the research program of the Foundation for Fundamental Research on Matter (FOM) ( #15PR3178-1 and #16NEPH05 to C.J.W.) and the VICI program (to C.C.H.); by the program 34 FP7/2007-2013/ under Research Executive Agency (REA) grant agreement 289581 (to C.P.F.); and by ERCVisionby3DSTIM , KFI16-1-2016-0177 , NVKP16-1-2016-0043 , and GINOP2.1.1-15-2016-00979 (to B.R.). Department of Biology, Science for Life, Utrecht University, Utrecht, 3584CH, Netherlands Laboratory of 3D Functional Network and Dendritic Imaging, Institute of Experimental Medicine, Hungarian Academy of Sciences, Budapest, 1083, Hungary Faculty of Information Technology, Pázmány Péter Catholic University, Budapest, 1083, Hungary Cited By :6 Export Date: 17 March 2021 Correspondence Address: Wierenga, C.J.; Department of Biology, Netherlands; email: c.j.wierenga@uu.nl Chemicals/CAS: glutamic acid, 11070-68-1, 138-15-8, 56-86-0, 6899-05-4; 1 (2,4 dichlorophenyl) 5 (4 iodophenyl) 4 methyl n (1 piperidyl) 1h pyrazole 3 carboxamide, 183232-66-8; AM 251; Endocannabinoids; Glutamic Acid; Piperidines; Pyrazoles; Receptor, Cannabinoid, CB1; Receptors, N-Methyl-D-Aspartate Funding details: 016.126.361 Funding details: Research Executive Agency, REA, 289581, ERCVisionby3DSTIM, GINOP2.1.1-15-2016-00979, KFI16-1-2016-0177 Funding details: Nederlandse Organisatie voor Wetenschappelijk Onderzoek, NWO, #016.126.361; to C.J.W. Funding details: Foundation for Fundamental Research on Matter, FOM, 15PR3178-1, 16NEPH05 Funding text 1: The authors thank René van Dorland for excellent technical support. This research was supported by the Netherlands Organization for Scientific Research , as part of the VIDI program ( #016.126.361; to C.J.W. ); the research program of the Foundation for Fundamental Research on Matter (FOM) ( #15PR3178-1 and #16NEPH05 to C.J.W.) and the VICI program (to C.C.H.); by the program 34 FP7/2007-2013/ under Research Executive Agency (REA) grant agreement 289581 (to C.P.F.); and by ERCVisionby3DSTIM , KFI16-1-2016-0177 , NVKP16-1-2016-0043 , and GINOP2.1.1-15-2016-00979 (to B.R.). Funding text 2: The authors thank René van Dorland for excellent technical support. This research was supported by the Netherlands Organization for Scientific Research, as part of the VIDI program (#016.126.361; to C.J.W.); the research program of the Foundation for Fundamental Research on Matter (FOM) (#15PR3178-1 and #16NEPH05 to C.J.W.) and the VICI program (to C.C.H.); by the program 34 FP7/2007-2013/ under Research Executive Agency (REA) grant agreement 289581 (to C.P.F.); and by ERCVisionby3DSTIM, KFI16-1-2016-0177, NVKP16-1-2016-0043, and GINOP2.1.1-15-2016-00979 (to B.R.). C.J.W. conceived and supervised the study. C.J.W. H.Y.H. and D.L.H.K. designed the experiments. H.Y.H. and D.L.H.K. performed the experiments and performed the analysis. C.P.F. performed and analyzed the experiments presented in Figures S1G–S1I. B.R. developed and provided DNI glutamate. C.C.H. provided critical input. C.J.W. H.Y.H. and D.L.H.K. wrote the paper, with critical input from all of the authors. B.R. is one of the founders of Femtonics and is a member of its scientific advisory board. Department of Biology, Science for Life, Utrecht University, Utrecht, 3584CH, Netherlands Laboratory of 3D Functional Network and Dendritic Imaging, Institute of Experimental Medicine, Hungarian Academy of Sciences, Budapest, 1083, Hungary Faculty of Information Technology, Pázmány Péter Catholic University, Budapest, 1083, Hungary Cited By :6 Export Date: 30 March 2021 Correspondence Address: Wierenga, C.J.; Department of Biology, Netherlands; email: c.j.wierenga@uu.nl Chemicals/CAS: glutamic acid, 11070-68-1, 138-15-8, 56-86-0, 6899-05-4; 1 (2,4 dichlorophenyl) 5 (4 iodophenyl) 4 methyl n (1 piperidyl) 1h pyrazole 3 carboxamide, 183232-66-8; AM 251; Endocannabinoids; Glutamic Acid; Piperidines; Pyrazoles; Receptor, Cannabinoid, CB1; Receptors, N-Methyl-D-Aspartate Funding details: Research Executive Agency, REA, 289581, ERCVisionby3DSTIM, GINOP2.1.1-15-2016-00979, NVKP16-1-2016-0043 Funding details: Stichting voor Fundamenteel Onderzoek der Materie, FOM, 15PR3178-1, 16NEPH05 Funding details: Nederlandse Organisatie voor Wetenschappelijk Onderzoek, NWO, 016.126.361 Funding details: Foundation for Fundamental Research on Matter, FOM, 34 FP7/2007-2013/ Funding text 1: The authors thank René van Dorland for excellent technical support. This research was supported by the Netherlands Organization for Scientific Research , as part of the VIDI program ( #016.126.361; to C.J.W. ); the research program of the Foundation for Fundamental Research on Matter (FOM) ( #15PR3178-1 and #16NEPH05 to C.J.W.) and the VICI program (to C.C.H.); by the program 34 FP7/2007-2013/ under Research Executive Agency (REA) grant agreement 289581 (to C.P.F.); and by ERCVisionby3DSTIM , KFI16-1-2016-0177 , NVKP16-1-2016-0043 , and GINOP2.1.1-15-2016-00979 (to B.R.). Funding text 2: The authors thank Ren? van Dorland for excellent technical support. This research was supported by the Netherlands Organization for Scientific Research, as part of the VIDI program (#016.126.361; to C.J.W.); the research program of the Foundation for Fundamental Research on Matter (FOM) (#15PR3178-1 and #16NEPH05 to C.J.W.) and the VICI program (to C.C.H.); by the program 34 FP7/2007-2013/ under Research Executive Agency (REA) grant agreement 289581 (to C.P.F.); and by ERCVisionby3DSTIM, KFI16-1-2016-0177, NVKP16-1-2016-0043, and GINOP2.1.1-15-2016-00979 (to B.R.). C.J.W. conceived and supervised the study. C.J.W. H.Y.H. and D.L.H.K. designed the experiments. H.Y.H. and D.L.H.K. performed the experiments and performed the analysis. C.P.F. performed and analyzed the experiments presented in Figures S1G?S1I. B.R. developed and provided DNI glutamate. C.C.H. provided critical input. C.J.W. H.Y.H. and D.L.H.K. wrote the paper, with critical input from all of the authors. B.R. is one of the founders of Femtonics and is a member of its scientific advisory board. Funding text 3: The authors thank René van Dorland for excellent technical support. This research was supported by the Netherlands Organization for Scientific Research, as part of the VIDI program (#016.126.361; to C.J.W.); the research program of the Foundation for Fundamental Research on Matter (FOM) (#15PR3178-1 and #16NEPH05 to C.J.W.) and the VICI program (to C.C.H.); by the program 34 FP7/2007-2013/ under Research Executive Agency (REA) grant agreement 289581 (to C.P.F.); and by ERCVisionby3DSTIM, KFI16-1-2016-0177, NVKP16-1-2016-0043, and GINOP2.1.1-15-2016-00979 (to B.R.). C.J.W. conceived and supervised the study. C.J.W. H.Y.H. and D.L.H.K. designed the experiments. H.Y.H. and D.L.H.K. performed the experiments and performed the analysis. C.P.F. performed and analyzed the experiments presented in Figures S1G–S1I. B.R. developed and provided DNI glutamate. C.C.H. provided critical input. C.J.W. H.Y.H. and D.L.H.K. wrote the paper, with critical input from all of the authors. B.R. is one of the founders of Femtonics and is a member of its scientific advisory board. Department of Biology, Science for Life, Utrecht University, Utrecht, 3584CH, Netherlands Laboratory of 3D Functional Network and Dendritic Imaging, Institute of Experimental Medicine, Hungarian Academy of Sciences, Budapest, 1083, Hungary Faculty of Information Technology, Pázmány Péter Catholic University, Budapest, 1083, Hungary Cited By :6 Export Date: 7 April 2021 Correspondence Address: Wierenga, C.J.; Department of Biology, Netherlands; email: c.j.wierenga@uu.nl Chemicals/CAS: glutamic acid, 11070-68-1, 138-15-8, 56-86-0, 6899-05-4; 1 (2,4 dichlorophenyl) 5 (4 iodophenyl) 4 methyl n (1 piperidyl) 1h pyrazole 3 carboxamide, 183232-66-8; AM 251; Endocannabinoids; Glutamic Acid; Piperidines; Pyrazoles; Receptor, Cannabinoid, CB1; Receptors, N-Methyl-D-Aspartate Funding details: Research Executive Agency, REA, 289581, ERCVisionby3DSTIM, GINOP2.1.1-15-2016-00979, NVKP16-1-2016-0043 Funding details: Stichting voor Fundamenteel Onderzoek der Materie, FOM, 15PR3178-1, 16NEPH05 Funding details: Nederlandse Organisatie voor Wetenschappelijk Onderzoek, NWO, 016.126.361 Funding details: Foundation for Fundamental Research on Matter, FOM, 34 FP7/2007-2013/ Funding text 1: The authors thank René van Dorland for excellent technical support. This research was supported by the Netherlands Organization for Scientific Research , as part of the VIDI program ( #016.126.361; to C.J.W. ); the research program of the Foundation for Fundamental Research on Matter (FOM) ( #15PR3178-1 and #16NEPH05 to C.J.W.) and the VICI program (to C.C.H.); by the program 34 FP7/2007-2013/ under Research Executive Agency (REA) grant agreement 289581 (to C.P.F.); and by ERCVisionby3DSTIM , KFI16-1-2016-0177 , NVKP16-1-2016-0043 , and GINOP2.1.1-15-2016-00979 (to B.R.). Funding text 2: The authors thank Ren? van Dorland for excellent technical support. This research was supported by the Netherlands Organization for Scientific Research, as part of the VIDI program (#016.126.361; to C.J.W.); the research program of the Foundation for Fundamental Research on Matter (FOM) (#15PR3178-1 and #16NEPH05 to C.J.W.) and the VICI program (to C.C.H.); by the program 34 FP7/2007-2013/ under Research Executive Agency (REA) grant agreement 289581 (to C.P.F.); and by ERCVisionby3DSTIM, KFI16-1-2016-0177, NVKP16-1-2016-0043, and GINOP2.1.1-15-2016-00979 (to B.R.). C.J.W. conceived and supervised the study. C.J.W. H.Y.H. and D.L.H.K. designed the experiments. H.Y.H. and D.L.H.K. performed the experiments and performed the analysis. C.P.F. performed and analyzed the experiments presented in Figures S1G?S1I. B.R. developed and provided DNI glutamate. C.C.H. provided critical input. C.J.W. H.Y.H. and D.L.H.K. wrote the paper, with critical input from all of the authors. B.R. is one of the founders of Femtonics and is a member of its scientific advisory board. Funding text 3: The authors thank René van Dorland for excellent technical support. This research was supported by the Netherlands Organization for Scientific Research, as part of the VIDI program (#016.126.361; to C.J.W.); the research program of the Foundation for Fundamental Research on Matter (FOM) (#15PR3178-1 and #16NEPH05 to C.J.W.) and the VICI program (to C.C.H.); by the program 34 FP7/2007-2013/ under Research Executive Agency (REA) grant agreement 289581 (to C.P.F.); and by ERCVisionby3DSTIM, KFI16-1-2016-0177, NVKP16-1-2016-0043, and GINOP2.1.1-15-2016-00979 (to B.R.). C.J.W. conceived and supervised the study. C.J.W. H.Y.H. and D.L.H.K. designed the experiments. H.Y.H. and D.L.H.K. performed the experiments and performed the analysis. C.P.F. performed and analyzed the experiments presented in Figures S1G–S1I. B.R. developed and provided DNI glutamate. C.C.H. provided critical input. C.J.W. H.Y.H. and D.L.H.K. wrote the paper, with critical input from all of the authors. B.R. is one of the founders of Femtonics and is a member of its scientific advisory board. Department of Biology, Science for Life, Utrecht University, Utrecht, 3584CH, Netherlands Laboratory of 3D Functional Network and Dendritic Imaging, Institute of Experimental Medicine, Hungarian Academy of Sciences, Budapest, 1083, Hungary Faculty of Information Technology, Pázmány Péter Catholic University, Budapest, 1083, Hungary Cited By :6 Export Date: 12 April 2021 Correspondence Address: Wierenga, C.J.; Department of Biology, Netherlands; email: c.j.wierenga@uu.nl Chemicals/CAS: glutamic acid, 11070-68-1, 138-15-8, 56-86-0, 6899-05-4; 1 (2,4 dichlorophenyl) 5 (4 iodophenyl) 4 methyl n (1 piperidyl) 1h pyrazole 3 carboxamide, 183232-66-8; AM 251; Endocannabinoids; Glutamic Acid; Piperidines; Pyrazoles; Receptor, Cannabinoid, CB1; Receptors, N-Methyl-D-Aspartate Funding details: Research Executive Agency, REA, 289581, ERCVisionby3DSTIM, GINOP2.1.1-15-2016-00979, NVKP16-1-2016-0043 Funding details: Stichting voor Fundamenteel Onderzoek der Materie, FOM, 15PR3178-1, 16NEPH05 Funding details: Nederlandse Organisatie voor Wetenschappelijk Onderzoek, NWO, 016.126.361 Funding details: Foundation for Fundamental Research on Matter, FOM, 34 FP7/2007-2013/ Funding text 1: The authors thank René van Dorland for excellent technical support. This research was supported by the Netherlands Organization for Scientific Research , as part of the VIDI program ( #016.126.361; to C.J.W. ); the research program of the Foundation for Fundamental Research on Matter (FOM) ( #15PR3178-1 and #16NEPH05 to C.J.W.) and the VICI program (to C.C.H.); by the program 34 FP7/2007-2013/ under Research Executive Agency (REA) grant agreement 289581 (to C.P.F.); and by ERCVisionby3DSTIM , KFI16-1-2016-0177 , NVKP16-1-2016-0043 , and GINOP2.1.1-15-2016-00979 (to B.R.). Funding text 2: The authors thank Ren? van Dorland for excellent technical support. This research was supported by the Netherlands Organization for Scientific Research, as part of the VIDI program (#016.126.361; to C.J.W.); the research program of the Foundation for Fundamental Research on Matter (FOM) (#15PR3178-1 and #16NEPH05 to C.J.W.) and the VICI program (to C.C.H.); by the program 34 FP7/2007-2013/ under Research Executive Agency (REA) grant agreement 289581 (to C.P.F.); and by ERCVisionby3DSTIM, KFI16-1-2016-0177, NVKP16-1-2016-0043, and GINOP2.1.1-15-2016-00979 (to B.R.). C.J.W. conceived and supervised the study. C.J.W. H.Y.H. and D.L.H.K. designed the experiments. H.Y.H. and D.L.H.K. performed the experiments and performed the analysis. C.P.F. performed and analyzed the experiments presented in Figures S1G?S1I. B.R. developed and provided DNI glutamate. C.C.H. provided critical input. C.J.W. H.Y.H. and D.L.H.K. wrote the paper, with critical input from all of the authors. B.R. is one of the founders of Femtonics and is a member of its scientific advisory board. Funding text 3: The authors thank René van Dorland for excellent technical support. This research was supported by the Netherlands Organization for Scientific Research, as part of the VIDI program (#016.126.361; to C.J.W.); the research program of the Foundation for Fundamental Research on Matter (FOM) (#15PR3178-1 and #16NEPH05 to C.J.W.) and the VICI program (to C.C.H.); by the program 34 FP7/2007-2013/ under Research Executive Agency (REA) grant agreement 289581 (to C.P.F.); and by ERCVisionby3DSTIM, KFI16-1-2016-0177, NVKP16-1-2016-0043, and GINOP2.1.1-15-2016-00979 (to B.R.). C.J.W. conceived and supervised the study. C.J.W. H.Y.H. and D.L.H.K. designed the experiments. H.Y.H. and D.L.H.K. performed the experiments and performed the analysis. C.P.F. performed and analyzed the experiments presented in Figures S1G–S1I. B.R. developed and provided DNI glutamate. C.C.H. provided critical input. C.J.W. H.Y.H. and D.L.H.K. wrote the paper, with critical input from all of the authors. B.R. is one of the founders of Femtonics and is a member of its scientific advisory board. Department of Biology, Science for Life, Utrecht University, Utrecht, 3584CH, Netherlands Laboratory of 3D Functional Network and Dendritic Imaging, Institute of Experimental Medicine, Hungarian Academy of Sciences, Budapest, 1083, Hungary Faculty of Information Technology, Pázmány Péter Catholic University, Budapest, 1083, Hungary Cited By :6 Export Date: 20 April 2021 Correspondence Address: Wierenga, C.J.; Department of Biology, Netherlands; email: c.j.wierenga@uu.nl Chemicals/CAS: glutamic acid, 11070-68-1, 138-15-8, 56-86-0, 6899-05-4; 1 (2,4 dichlorophenyl) 5 (4 iodophenyl) 4 methyl n (1 piperidyl) 1h pyrazole 3 carboxamide, 183232-66-8; AM 251; Endocannabinoids; Glutamic Acid; Piperidines; Pyrazoles; Receptor, Cannabinoid, CB1; Receptors, N-Methyl-D-Aspartate Funding details: Research Executive Agency, REA, 289581, ERCVisionby3DSTIM, GINOP2.1.1-15-2016-00979, NVKP16-1-2016-0043 Funding details: Stichting voor Fundamenteel Onderzoek der Materie, FOM, 15PR3178-1, 16NEPH05 Funding details: Nederlandse Organisatie voor Wetenschappelijk Onderzoek, NWO, 016.126.361 Funding details: Foundation for Fundamental Research on Matter, FOM, 34 FP7/2007-2013/ Funding text 1: The authors thank René van Dorland for excellent technical support. This research was supported by the Netherlands Organization for Scientific Research , as part of the VIDI program ( #016.126.361; to C.J.W. ); the research program of the Foundation for Fundamental Research on Matter (FOM) ( #15PR3178-1 and #16NEPH05 to C.J.W.) and the VICI program (to C.C.H.); by the program 34 FP7/2007-2013/ under Research Executive Agency (REA) grant agreement 289581 (to C.P.F.); and by ERCVisionby3DSTIM , KFI16-1-2016-0177 , NVKP16-1-2016-0043 , and GINOP2.1.1-15-2016-00979 (to B.R.). Funding text 2: The authors thank Ren? van Dorland for excellent technical support. This research was supported by the Netherlands Organization for Scientific Research, as part of the VIDI program (#016.126.361; to C.J.W.); the research program of the Foundation for Fundamental Research on Matter (FOM) (#15PR3178-1 and #16NEPH05 to C.J.W.) and the VICI program (to C.C.H.); by the program 34 FP7/2007-2013/ under Research Executive Agency (REA) grant agreement 289581 (to C.P.F.); and by ERCVisionby3DSTIM, KFI16-1-2016-0177, NVKP16-1-2016-0043, and GINOP2.1.1-15-2016-00979 (to B.R.). C.J.W. conceived and supervised the study. C.J.W. H.Y.H. and D.L.H.K. designed the experiments. H.Y.H. and D.L.H.K. performed the experiments and performed the analysis. C.P.F. performed and analyzed the experiments presented in Figures S1G?S1I. B.R. developed and provided DNI glutamate. C.C.H. provided critical input. C.J.W. H.Y.H. and D.L.H.K. wrote the paper, with critical input from all of the authors. B.R. is one of the founders of Femtonics and is a member of its scientific advisory board. Funding text 3: The authors thank René van Dorland for excellent technical support. This research was supported by the Netherlands Organization for Scientific Research, as part of the VIDI program (#016.126.361; to C.J.W.); the research program of the Foundation for Fundamental Research on Matter (FOM) (#15PR3178-1 and #16NEPH05 to C.J.W.) and the VICI program (to C.C.H.); by the program 34 FP7/2007-2013/ under Research Executive Agency (REA) grant agreement 289581 (to C.P.F.); and by ERCVisionby3DSTIM, KFI16-1-2016-0177, NVKP16-1-2016-0043, and GINOP2.1.1-15-2016-00979 (to B.R.). C.J.W. conceived and supervised the study. C.J.W. H.Y.H. and D.L.H.K. designed the experiments. H.Y.H. and D.L.H.K. performed the experiments and performed the analysis. C.P.F. performed and analyzed the experiments presented in Figures S1G–S1I. B.R. developed and provided DNI glutamate. C.C.H. provided critical input. C.J.W. H.Y.H. and D.L.H.K. wrote the paper, with critical input from all of the authors. B.R. is one of the founders of Femtonics and is a member of its scientific advisory board. Department of Biology, Science for Life, Utrecht University, Utrecht, 3584CH, Netherlands Laboratory of 3D Functional Network and Dendritic Imaging, Institute of Experimental Medicine, Hungarian Academy of Sciences, Budapest, 1083, Hungary Faculty of Information Technology, Pázmány Péter Catholic University, Budapest, 1083, Hungary Cited By :6 Export Date: 21 April 2021 Correspondence Address: Wierenga, C.J.; Department of Biology, Netherlands; email: c.j.wierenga@uu.nl Chemicals/CAS: glutamic acid, 11070-68-1, 138-15-8, 56-86-0, 6899-05-4; 1 (2,4 dichlorophenyl) 5 (4 iodophenyl) 4 methyl n (1 piperidyl) 1h pyrazole 3 carboxamide, 183232-66-8; AM 251; Endocannabinoids; Glutamic Acid; Piperidines; Pyrazoles; Receptor, Cannabinoid, CB1; Receptors, N-Methyl-D-Aspartate Funding details: Research Executive Agency, REA, 289581, ERCVisionby3DSTIM, GINOP2.1.1-15-2016-00979, NVKP16-1-2016-0043 Funding details: Stichting voor Fundamenteel Onderzoek der Materie, FOM, 15PR3178-1, 16NEPH05 Funding details: Nederlandse Organisatie voor Wetenschappelijk Onderzoek, NWO, 016.126.361 Funding details: Foundation for Fundamental Research on Matter, FOM, 34 FP7/2007-2013/ Funding text 1: The authors thank René van Dorland for excellent technical support. This research was supported by the Netherlands Organization for Scientific Research , as part of the VIDI program ( #016.126.361; to C.J.W. ); the research program of the Foundation for Fundamental Research on Matter (FOM) ( #15PR3178-1 and #16NEPH05 to C.J.W.) and the VICI program (to C.C.H.); by the program 34 FP7/2007-2013/ under Research Executive Agency (REA) grant agreement 289581 (to C.P.F.); and by ERCVisionby3DSTIM , KFI16-1-2016-0177 , NVKP16-1-2016-0043 , and GINOP2.1.1-15-2016-00979 (to B.R.). Funding text 2: The authors thank Ren? van Dorland for excellent technical support. This research was supported by the Netherlands Organization for Scientific Research, as part of the VIDI program (#016.126.361; to C.J.W.); the research program of the Foundation for Fundamental Research on Matter (FOM) (#15PR3178-1 and #16NEPH05 to C.J.W.) and the VICI program (to C.C.H.); by the program 34 FP7/2007-2013/ under Research Executive Agency (REA) grant agreement 289581 (to C.P.F.); and by ERCVisionby3DSTIM, KFI16-1-2016-0177, NVKP16-1-2016-0043, and GINOP2.1.1-15-2016-00979 (to B.R.). C.J.W. conceived and supervised the study. C.J.W. H.Y.H. and D.L.H.K. designed the experiments. H.Y.H. and D.L.H.K. performed the experiments and performed the analysis. C.P.F. performed and analyzed the experiments presented in Figures S1G?S1I. B.R. developed and provided DNI glutamate. C.C.H. provided critical input. C.J.W. H.Y.H. and D.L.H.K. wrote the paper, with critical input from all of the authors. B.R. is one of the founders of Femtonics and is a member of its scientific advisory board. Funding text 3: The authors thank René van Dorland for excellent technical support. This research was supported by the Netherlands Organization for Scientific Research, as part of the VIDI program (#016.126.361; to C.J.W.); the research program of the Foundation for Fundamental Research on Matter (FOM) (#15PR3178-1 and #16NEPH05 to C.J.W.) and the VICI program (to C.C.H.); by the program 34 FP7/2007-2013/ under Research Executive Agency (REA) grant agreement 289581 (to C.P.F.); and by ERCVisionby3DSTIM, KFI16-1-2016-0177, NVKP16-1-2016-0043, and GINOP2.1.1-15-2016-00979 (to B.R.). C.J.W. conceived and supervised the study. C.J.W. H.Y.H. and D.L.H.K. designed the experiments. H.Y.H. and D.L.H.K. performed the experiments and performed the analysis. C.P.F. performed and analyzed the experiments presented in Figures S1G–S1I. B.R. developed and provided DNI glutamate. C.C.H. provided critical input. C.J.W. H.Y.H. and D.L.H.K. wrote the paper, with critical input from all of the authors. B.R. is one of the founders of Femtonics and is a member of its scientific advisory board. Department of Biology, Science for Life, Utrecht University, Utrecht, 3584CH, Netherlands Laboratory of 3D Functional Network and Dendritic Imaging, Institute of Experimental Medicine, Hungarian Academy of Sciences, Budapest, 1083, Hungary Faculty of Information Technology, Pázmány Péter Catholic University, Budapest, 1083, Hungary Cited By :6 Export Date: 23 April 2021 Correspondence Address: Wierenga, C.J.; Department of Biology, Netherlands; email: c.j.wierenga@uu.nl Chemicals/CAS: glutamic acid, 11070-68-1, 138-15-8, 56-86-0, 6899-05-4; 1 (2,4 dichlorophenyl) 5 (4 iodophenyl) 4 methyl n (1 piperidyl) 1h pyrazole 3 carboxamide, 183232-66-8; AM 251; Endocannabinoids; Glutamic Acid; Piperidines; Pyrazoles; Receptor, Cannabinoid, CB1; Receptors, N-Methyl-D-Aspartate Funding details: Research Executive Agency, REA, 289581, ERCVisionby3DSTIM, GINOP2.1.1-15-2016-00979, NVKP16-1-2016-0043 Funding details: Stichting voor Fundamenteel Onderzoek der Materie, FOM, 15PR3178-1, 16NEPH05 Funding details: Nederlandse Organisatie voor Wetenschappelijk Onderzoek, NWO, 016.126.361 Funding details: Foundation for Fundamental Research on Matter, FOM, 34 FP7/2007-2013/ Funding text 1: The authors thank René van Dorland for excellent technical support. This research was supported by the Netherlands Organization for Scientific Research , as part of the VIDI program ( #016.126.361; to C.J.W. ); the research program of the Foundation for Fundamental Research on Matter (FOM) ( #15PR3178-1 and #16NEPH05 to C.J.W.) and the VICI program (to C.C.H.); by the program 34 FP7/2007-2013/ under Research Executive Agency (REA) grant agreement 289581 (to C.P.F.); and by ERCVisionby3DSTIM , KFI16-1-2016-0177 , NVKP16-1-2016-0043 , and GINOP2.1.1-15-2016-00979 (to B.R.). Funding text 2: The authors thank Ren? van Dorland for excellent technical support. This research was supported by the Netherlands Organization for Scientific Research, as part of the VIDI program (#016.126.361; to C.J.W.); the research program of the Foundation for Fundamental Research on Matter (FOM) (#15PR3178-1 and #16NEPH05 to C.J.W.) and the VICI program (to C.C.H.); by the program 34 FP7/2007-2013/ under Research Executive Agency (REA) grant agreement 289581 (to C.P.F.); and by ERCVisionby3DSTIM, KFI16-1-2016-0177, NVKP16-1-2016-0043, and GINOP2.1.1-15-2016-00979 (to B.R.). C.J.W. conceived and supervised the study. C.J.W. H.Y.H. and D.L.H.K. designed the experiments. H.Y.H. and D.L.H.K. performed the experiments and performed the analysis. C.P.F. performed and analyzed the experiments presented in Figures S1G?S1I. B.R. developed and provided DNI glutamate. C.C.H. provided critical input. C.J.W. H.Y.H. and D.L.H.K. wrote the paper, with critical input from all of the authors. B.R. is one of the founders of Femtonics and is a member of its scientific advisory board. Funding text 3: The authors thank René van Dorland for excellent technical support. This research was supported by the Netherlands Organization for Scientific Research, as part of the VIDI program (#016.126.361; to C.J.W.); the research program of the Foundation for Fundamental Research on Matter (FOM) (#15PR3178-1 and #16NEPH05 to C.J.W.) and the VICI program (to C.C.H.); by the program 34 FP7/2007-2013/ under Research Executive Agency (REA) grant agreement 289581 (to C.P.F.); and by ERCVisionby3DSTIM, KFI16-1-2016-0177, NVKP16-1-2016-0043, and GINOP2.1.1-15-2016-00979 (to B.R.). C.J.W. conceived and supervised the study. C.J.W. H.Y.H. and D.L.H.K. designed the experiments. H.Y.H. and D.L.H.K. performed the experiments and performed the analysis. C.P.F. performed and analyzed the experiments presented in Figures S1G–S1I. B.R. developed and provided DNI glutamate. C.C.H. provided critical input. C.J.W. H.Y.H. and D.L.H.K. wrote the paper, with critical input from all of the authors. B.R. is one of the founders of Femtonics and is a member of its scientific advisory board. Department of Biology, Science for Life, Utrecht University, Utrecht, 3584CH, Netherlands Laboratory of 3D Functional Network and Dendritic Imaging, Institute of Experimental Medicine, Hungarian Academy of Sciences, Budapest, 1083, Hungary Faculty of Information Technology, Pázmány Péter Catholic University, Budapest, 1083, Hungary Cited By :6 Export Date: 6 May 2021 Correspondence Address: Wierenga, C.J.; Department of Biology, Netherlands; email: c.j.wierenga@uu.nl Chemicals/CAS: glutamic acid, 11070-68-1, 138-15-8, 56-86-0, 6899-05-4; 1 (2,4 dichlorophenyl) 5 (4 iodophenyl) 4 methyl n (1 piperidyl) 1h pyrazole 3 carboxamide, 183232-66-8; AM 251; Endocannabinoids; Glutamic Acid; Piperidines; Pyrazoles; Receptor, Cannabinoid, CB1; Receptors, N-Methyl-D-Aspartate Funding details: Research Executive Agency, REA, 289581, ERCVisionby3DSTIM, GINOP2.1.1-15-2016-00979, NVKP16-1-2016-0043 Funding details: Stichting voor Fundamentee 0 false 2026-09-22T14:23:19.957+0000 2024-05-03T11:24:50.916+0000 2019-05-01T10:36:17.080+0000 true 10039043 Milánkovics Róbert /api/admin/10039043 Admin Róbert Milánkovics (PTE ÁOK admin 4) true 10039043 2025-03-22T18:50:53.836+0000 2025-03-22T18:50:53.836+0000 2020-01-08T19:37:51.803+0000 true 565 WoS import /api/admin/565 Admin import WoS (admin) true true false true 24 24 /api/publicationtype/24 PublicationType Journal Article 1 true 24 JournalArticle true 10000059 Article true 24 24 /api/publicationtype/24 PublicationType Journal Article 1 true 24 JournalArticle /api/subtype/10000059 Szakcikk SubType Article (Journal Article) 101 true 10000059 true 1 /api/category/1 Category Scientific true 1 Hu, Hai Yin Endocannabinoid Signaling Mediates Local Dendritic Coordination between Excitatory and Inhibitory Synapses true true /api/journal/10022692 REVIEWED CELL REPORTS 2639-1856 2211-1247 true false 10022692 false 10022692 true 2639-1856 2211-1247 Journal FOREIGN 27 3 666 + 666 15 2019 Dendritic inhibitory synapses are most efficient in modulating excitatory inputs localized on the same dendrite, but it is unknown whether their location is random or regulated. Here, we show that the formation of inhibitory synapses can be directed by excitatory synaptic activity on the same dendrite. We stimulated dendritic spines close to a GABAergic axon crossing by pairing two-photon glutamate uncaging with postsynaptic depolarization in CA1 pyramidal cells. We found that repeated spine stimulation promoted growth of a GABAergic bouton onto the same dendrite. The dendritic feedback signal required postsynaptic activation of DAGL, which produces the endocannabinoid 2-AG, and was mediated by CB1 receptors. We could also induce inhibitory bouton growth by local, brief applications of 2-AG. Our findings reveal a dendritic signaling mechanism to trigger growth of an inhibitory bouton at dendritic locations with strong excitatory synaptic activity, and this mechanism may serve to ensure inhibitory control over clustered excitatory inputs. true 2019 true true true false true false GOLD 2026-09-22 true https://doi.org/10.1016/j.celrep.2019.03.078 26 0 26 19 0 26 26 23 26 26 26 19 19 19 7 0 26 19 26 19 0 7 7 Folyóiratcikk Journal Article 24 25 Könyvrészlet Chapter in Book 25 1 Könyv Book 23 0 Egyéb konferenciaközlemény Conference paper 31 0 Egyéb konferenciakötet Conference proceedings 32 0 Oltalmi formák Protection forms 26 0 Disszertáció Thesis 28 0 Egyéb Miscellaneous 29 0 Alkotás Achievement 22 0 Kutatási adat Research data 33 0 Folyóiratcikk Journal Article 24 0 0 0 Könyvrészlet Chapter in Book 25 0 0 0 Könyv Book 23 0 0 0 Egyéb konferenciaközlemény Conference paper 31 0 0 0 Egyéb konferenciakötet Conference proceedings 32 0 0 0 Oltalmi formák Protection forms 26 0 0 0 Disszertáció Thesis 28 0 0 0 Egyéb Miscellaneous 29 0 0 0 Alkotás Achievement 22 0 0 0 Kutatási adat Research data 33 0 0 0 2019 0 1 0 1 0 2020 0 4 3 4 3 2021 0 3 0 3 0 2022 0 4 4 4 4 2023 0 5 3 5 3 2024 0 2 2 2 2 2025 0 3 3 3 3 2026 0 4 4 4 4 D1 false false false false 2020-01-06T11:21:54.060+0000 Információs Technológiai és Bionikai Kar (PPKE); Neuronhálózat és Dendritikus Aktivitás Kutatócs... (HRN KOKI) 1 14 2 6 0 true Language 10002 /api/language/10002 English Angol English true 2 true PersonAuthorship 86913875 /api/authorship/86913875 Hu, Hai Yin 1 0.16666667 true false Hu Hai Yin true false false AuthorshipType 1 /api/authorshiptype/1 Author 0 true 0 true false true PersonAuthorship 86913876 /api/authorship/86913876 Kruijssen, Dennis L. H. 2 0.16666667 false false Kruijssen Dennis L. H. true false false AuthorshipType 1 /api/authorshiptype/1 Author 0 true 0 true false true PersonAuthorship 86913877 /api/authorship/86913877 Frias, Catia P. 3 0.16666667 false false Frias Catia P. true false false AuthorshipType 1 /api/authorshiptype/1 Author 0 true 0 true false true PersonAuthorship 86913878 /api/authorship/86913878 Rozsa, Balazs [Rózsa J., Balázs (Idegtudomány, fizika), author] Információs Technológiai és Bionikai Kar (PPCU); Neuronhálózat és Dendritikus Aktivitás Kutatócs... 4 0.16666667 false false Author 10012926 /api/author/10012926 Balázs Rózsa J. 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Balázs true 10012926 true Rozsa Balazs true false false AuthorshipType 1 /api/authorshiptype/1 Author 0 true 0 true false true PersonAuthorship 86913879 /api/authorship/86913879 Hoogenraad, Casper C. 5 0.16666667 false false Hoogenraad Casper C. true false false AuthorshipType 1 /api/authorshiptype/1 Author 0 true 0 true false true PersonAuthorship 86913880 /api/authorship/86913880 Wierenga, Corette J. 6 0.16666667 false true Wierenga Corette J. true false false AuthorshipType 1 /api/authorshiptype/1 Author 0 true 0 true false true PublicationIdentifier 15576817 /api/publicationidentifier/15576817 DOI: 10.1016/j.celrep.2019.03.078 PlainSource 6 /api/publicationsource/6 DOI PublicationSourceType 10001 /api/publicationsourcetype/10001 DOI true true true DOI DOI https://doi.org/@@@ true true 6 true GOLD true IDENTICAL 10.1016/j.celrep.2019.03.078 https://doi.org/10.1016/j.celrep.2019.03.078 false true PublicationIdentifier 15576816 /api/publicationidentifier/15576816 WoS: 000464652000003 PlainSource 1 /api/publicationsource/1 WoS PublicationSourceType 10003 /api/publicationsourcetype/10003 Indexelő adatbázis false true true WoS WoS https://www.webofscience.com/wos/woscc/full-record/@@@ true true 1 true IDENTICAL 000464652000003 https://www.webofscience.com/wos/woscc/full-record/000464652000003 false true PublicationIdentifier 15618322 /api/publicationidentifier/15618322 Scopus: 85064084800 PlainSource 3 /api/publicationsource/3 Scopus PublicationSourceType 10003 /api/publicationsourcetype/10003 Indexelő adatbázis false true true Scopus Scopus http://www.scopus.com/record/display.url?origin=inward&eid=2-s2.0-@@@ true true 3 true IDENTICAL 85064084800 http://www.scopus.com/record/display.url?origin=inward&eid=2-s2.0-85064084800 false true PublicationIdentifier 23364936 /api/publicationidentifier/23364936 PubMed: 30995465 PlainSource 17 /api/publicationsource/17 PubMed PublicationSourceType 10003 /api/publicationsourcetype/10003 Indexelő adatbázis false true true PubMed PubMed http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db=PubMed&list_uids=@@@&dopt=Abstract true true 17 true IDENTICAL 30995465 http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db=PubMed&list_uids=30995465&dopt=Abstract false true Classification 10545 /api/classification/10545 Biological sciences true true SjrRating 10751784 /api/sjrrating/10751784 sjr:D1 (2019) Scopus - Biochemistry, Genetics and Molecular Biology (miscellaneous) CELL REPORTS 2211-1247 8 0.1 journal RatingType 10002 /api/ratingtype/10002 sjr sjr true true ClassificationExternal 1301 /api/classificationexternal/1301 Scopus - Biochemistry, Genetics and Molecular Biology (miscellaneous) true 1301 true D1 DIRECT true true /api/publication/30651814 Hu Hai Yin et al. Endocannabinoid Signaling Mediates Local Dendritic Coordination between Excitatory and Inhibitory Synapses. (2019) CELL REPORTS 2639-1856 2211-1247 27 3 666-+<div class="JournalArticle Publication long-list"> <div class="authors"> <img title="Forrásközlemény" style="float: left" src="/frontend/resources/grid/publication-core-icon.png"> <img title="Idézőközlemény" style="float: left" src="/frontend/resources/grid/publication-citation-icon.png"> <div class="autype autype0"> <span class="author-name" >Hu Hai Yin </span> ;    <span class="author-name" >Kruijssen Dennis L. H. </span> ;    <span class="author-name" >Frias Catia P. </span> ;    <span class="author-name" mtid="10012926"><a href="/gui2/?type=authors&mode=browse&sel=10012926" target="_blank">Rozsa Balazs (<span class="authorship-author-name">Rózsa J. Balázs</span> <span class="authorAux-mtmt"> Idegtudomány, fizika</span>) </a> </span> <span class="author-affil"><span title="Pázmány Péter Catholic University">PPCU</span>/Információs Technológiai és Bionikai Kar; <span title="Institute of Experimental Medicine">IEM</span>/<span title="Department of Pharmacology">DP</span>/Neuronhálózat és Dendritikus Aktivitás Kutatócsoport</span> ;    <span class="author-name" >Hoogenraad Casper C. </span> ;    <span class="author-name" >Wierenga Corette J. </span> </div> </div> <div class="title"><a href="/gui2/?mode=browse&params=publication;30651814" target="_blank">Endocannabinoid Signaling Mediates Local Dendritic Coordination between Excitatory and Inhibitory Synapses</a></div> <div> <span class="journal-title">CELL REPORTS</span> <span class="journal-issn">(<a target="_blank" href="https://portal.issn.org/resource/ISSN/2639-1856">2639-1856</a> <a target="_blank" href="https://portal.issn.org/resource/ISSN/2211-1247">2211-1247</a>)</span>: <span class="journal-volume">27</span> <span class="journal-issue">3</span> <span class="page"> pp 666-+ </span> <span class="year">(2019)</span> </div> <div class="pub-footer"> <span class="language" xmlns="http://www.w3.org/1999/html">Language: English | </span> <span class="identifiers"> <span class="id identifier oa_GOLD" title=" Gold "> <a style="color:blue" title="10.1016/j.celrep.2019.03.078" target="_blank" href="https://doi.org/10.1016/j.celrep.2019.03.078"> DOI </a> </span> <span class="id identifier oa_none" title="none"> <a style="color:blue" title="000464652000003" target="_blank" href="https://www.webofscience.com/wos/woscc/full-record/000464652000003"> WoS </a> </span> <span class="id identifier oa_none" title="none"> <a style="color:blue" title="85064084800" target="_blank" href="http://www.scopus.com/record/display.url?origin=inward&eid=2-s2.0-85064084800"> Scopus </a> </span> <span class="id identifier oa_none" title="none"> <a style="color:blue" title="30995465" target="_blank" href="http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db=PubMed&list_uids=30995465&dopt=Abstract"> PubMed </a> </span> </span> <OnlyViewableByAuthor><div class="ratings"> <div class="journal-subject">Journal subject: Scopus - Biochemistry, Genetics and Molecular Biology (miscellaneous)   Rank: D1</div> </div></OnlyViewableByAuthor> <div class="publication-citation" style="margin-left: 0.5cm;"> <span title="" class="citingPub-count">Citing papers: 26</span> | Independent citation: 19 | Self citation: 7 | Unknown citation: 0 | Number of citations in WoS: 23 | Number of citations in Scopus: 26 | WoS/Scopus assigned: 26 | Number of citations with DOI: 26 </div> <div class="publication-citation"> <a target="_blank" href="/api/publication?cond=citations.related;eq;30651814&sort=publishedYear,desc&sort=title"> Number of cited publications: 7 </a> </div> <div class="mtid"><span class="long-pub-mtid">Publication: 30651814</span> | <span class="status-data status-VALIDATED"> Validated </span> Core Citing | <span class="type-subtype">Journal Article ( Article ) </span> | <span class="pub-category">Scientific</span> | <span class="publication-sourceOfData">WoS XML</span> </div> <div class="lastModified">Last Modified: 2024.05.03. 13:24 Viktória Sifter (PPKE ITK admin 5) </div> <pre class="comment" style="margin-top: 0; margin-bottom: 0;"><u>Comments</u>: Department of Biology, Science for Life, Utrecht University, Utrecht, 3584CH, Netherlands Laboratory of 3D Functional Network and Dendritic Imaging, Institute of Experimental Medicine, Hungarian Academy of Sciences, Budapest, 1083, Hungary Faculty of Information Technology, Pázmány Péter Catholic University, Budapest, 1083, Hungary ...</pre> </div></div>