New palladium (II) complexes containing phosphine-nitrogen ligands and their use as catalysts in aminocarbonylation reaction

Aranda, Braulio; Moya, Sergio A.; Vega, Andres; Valdebenito, Gonzalo; Ramirez-Lopez, Sofia; Aguirre, Pedro

Angol nyelvű Tudományos Szakcikk (Folyóiratcikk)
Megjelent: APPLIED ORGANOMETALLIC CHEMISTRY 0268-2605 1099-0739 33 (4) Paper: e4709 , 9 p. 2019
  • SJR Scopus - Chemistry (miscellaneous): Q2
    Aminocarbonylation of aryl halides, homogeneously catalysed by palladium, is an efficient method that can be employed for obtaining amides for pharmaceutical and synthetic applications.In this work, palladium (II) complexes containing P<^>N ligands were studied as catalysts in the aminocarbonylation of iodobenzene in the presence of diethylamine. Two types of systems were used: a palladium (II) complex formed in situ; and one prepared prior to the catalytic reaction. In general, the palladium complexes studied achieved high conversions in an average reaction time of less than 2 hr, which is less than that for the standard system (Pd (II)/PPh3) used. The pre-synthesized complexes were faster than their in situ counterparts, as the latter require an induction time to form the Pd/P<^>N species. The structure and electronic properties of the ligand P<^>N can influence both the activity and the selectivity of the reaction, stabilizing the acyl-palladium intermediates formed in a better manner.
    Hivatkozás stílusok: IEEEACMAPAChicagoHarvardCSLMásolásNyomtatás
    2020-08-10 20:48