Az orvos-, egészségtudományi- és gyógyszerészképzés tudományos műhelyeinek fejlesztése(EFOP-3.6.3-VEKOP-16-2017-00009)
Funder: EFOP-VEKOP
Liver diseases such as liver cirrhosis, primary and metastatic liver cancers are still
a major medical challenge. Syndecan-1 is one of the most important proteoglycans in
the liver. Syndecan-1 is normally expressed on the surfaces of hepatocytes and cholangiocytes.
Due to liver diseases the amount of syndecan-1 increases in the liver. Despite the
emerging data of the biological function of syndecan-1, the clinical usefulness of
this proteoglycan is still unknown. In our study we correlated syndecan-1 expression
to clinico-pathological data. We found that syndecan-1 proved to be a good marker
for hepatitis C virus based hepatocellular carcinoma and increased with liver dysfunction.
