In crustaceans as in other arthropods, the circulating hemocytes are vital for protecting
the animal against attacking microorganisms. As many hemocytes are destroyed early
during an infection, new hemocytes must fast get in place to prevent disperse of a
pathogenic microbe, In order to understand the hematopoietic process in more detail
we here report a complete proteomic analysis from purified cell types from the APC
of the hematopoietic tissue, via the remaining parts of the HPT to the mature semigranular
and granular hemocytes. Several possible cell type specific proteins are detected
and new putative biomarkers within the crayfish hematopoietic lineage that can be
used to increase the understanding of how the differentiation process is regulated
is described.