https://m2.mtmt.hu/ eng 2026-06-25 10:29 JournalArticle 30485260 VALIDATED true Nanomedicine Research and Education Center, Department of Pathophysiology, Semmelweis University, Budapest, Hungary SeroScience Ltd, Budapest, Hungary Department of Pharmacokinetics and Biopharmaceutics, Institute of Biomedical Sciences, Tokushima University, Tokushima, Japan Laboratory of Membrane and Liposome Research, Department of Biochemistry and Molecular Biology, Institute for Medical Research Israel-Canada (IMRIC), The Hebrew University-Hadassah Medical School, Jerusalem, Israel Department of Nanobiotechnology and Regenerative Medicine, Faculty of Health, Miskolc University, Miskolc, Hungary Cited By :23 Export Date: 31 May 2024 Correspondence Address: Szebeni, J.; Nanomedicine Research and Education Center, Nagyvárad tér 4, Hungary; email: jszebeni2@gmail.com Chemicals/CAS: alternative complement pathway C3 C5 convertase, 80295-62-1, 80295-67-6; complement component C3d, 80295-45-0; Complement C3b; Immunologic Factors; Liposomes; Polystyrenes 0 false 2026-05-19T03:20:58.587+0000 2022-11-21T11:11:49.249+0000 2019-03-01T22:07:07.345+0000 true 565 WoS import /api/admin/565 Admin true 2024-06-03T09:44:46.228+0000 2022-11-21T11:11:49.596+0000 true 10062250 Molnár-Taga Márta /api/admin/10062250 Admin true 10062250 true false true 24 24 /api/publicationtype/24 PublicationType 1 true 24 JournalArticle true 10000059 Article true 24 24 /api/publicationtype/24 PublicationType 1 true 24 JournalArticle /api/subtype/10000059 Szakcikk SubType 101 true 10000059 true 1 /api/category/1 Category true 1 Meszaros, Tamas Involvement of complement activation in the pulmonary vasoactivity of polystyrene nanoparticles in pigs: unique surface properties underlying alternative pathway activation and instant opsonization true true /api/journal/10007040 REVIEWED true false 10007040 false 10007040 true 1176-9114 1178-2013 Journal FOREIGN 13 6345 6357 6345 13 2018 Background: It has been proposed that many hypersensitivity reactions to nanopharmaceuticals represent complement (C)-activation-related pseudoallergy (CARPA), and that pigs provide a sensitive animal model to study the phenomenon. However, a recent study suggested that pulmonary hypertension, the pivotal symptom of porcine CARPA, is not mediated by C in cases of polystyrene nanoparticle (PS-NP)-induced reactions. true true 2019 true true true false true false GOLD 2026-05-19 true https://doi.org/10.2147/IJN.S161369 27 0 27 13 11 27 26 25 24 27 27 13 13 13 14 0 27 13 27 13 0 14 14 Folyóiratcikk Journal Article 24 26 Könyvrészlet Chapter in Book 25 1 Könyv Book 23 0 Egyéb konferenciaközlemény Conference paper 31 0 Egyéb konferenciakötet Conference proceedings 32 0 Oltalmi formák Protection forms 26 0 Disszertáció Thesis 28 0 Egyéb Miscellaneous 29 0 Alkotás Achievement 22 0 Kutatási adat Research data 33 0 Folyóiratcikk Journal Article 24 0 0 0 Könyvrészlet Chapter in Book 25 0 0 0 Könyv Book 23 0 0 0 Egyéb konferenciaközlemény Conference paper 31 0 0 0 Egyéb konferenciakötet Conference proceedings 32 0 0 0 Oltalmi formák Protection forms 26 0 0 0 Disszertáció Thesis 28 0 0 0 Egyéb Miscellaneous 29 0 0 0 Alkotás Achievement 22 0 0 0 Kutatási adat Research data 33 0 0 0 2018 0 1 0 1 0 2019 0 5 1 5 1 2020 0 3 2 3 2 2021 0 6 4 6 4 2022 0 4 2 4 2 2023 0 3 1 3 1 2024 0 1 0 1 0 2025 0 2 1 2 1 2026 0 2 2 2 2 Q1 false 10024742 false false false 2019-03-10T13:26:46.609+0000 Elméleti Egészségtudományok Intézete (ME / ETK); 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<span title="Semmelweis University">SU</span>/<span title="Faculty of Medicine">FM</span>/<span title="Instituties">I</span>/<span title="Department of Pathophysiology">DP</span>/Nanomedicina Kutató és Oktató Központ</span> ;&nbsp;&nbsp;&nbsp; <span class="author-name" mtid="10024742"><a href="/gui2/?type=authors&mode=browse&sel=10024742" target="_blank">Kozma Gergely Tibor<sup>*</sup> (<span class="authorship-author-name">Kozma Gergely Tibor</span> <span class="authorAux-mtmt"> Immunológia, Molekuláris biológia</span>) </a> </span> ;&nbsp;&nbsp;&nbsp; <span class="author-name" >Shimizu Taro </span> ;&nbsp;&nbsp;&nbsp; <span class="author-name" >Miyahara Koga </span> ;&nbsp;&nbsp;&nbsp; <span class="author-name" >Turjeman Keren </span> ;&nbsp;&nbsp;&nbsp; <span class="author-name" >Ishida Tatsuhiro </span> ;&nbsp;&nbsp;&nbsp; <span class="author-name" >Barenholz Yechezkel </span> ;&nbsp;&nbsp;&nbsp; <span class="author-name" >Urbanics Rudolf </span> ;&nbsp;&nbsp;&nbsp; <span class="author-name" mtid="10003266"><a href="/gui2/?type=authors&mode=browse&sel=10003266" target="_blank">Szebeni Janos ✉ (<span class="authorship-author-name">Szebeni János</span> <span class="authorAux-mtmt"> Klinikai orvostudomány, immunológia, nanomedicina</span>) </a> </span> <span class="author-affil"><span title="Semmelweis University">SU</span>/<span title="Faculty of Medicine">FM</span>/<span title="Instituties">I</span>/Department of Pathophysiology; <span title="Semmelweis University">SU</span>/<span title="Faculty of Medicine">FM</span>/<span title="Instituties">I</span>/<span title="Department of Pathophysiology">DP</span>/Nanomedicina Kutató és Oktató Központ; <span title="University of Miskolc">UM</span>/<span title="Faculty of Health Care Studies">FHCS</span>/Elméleti Egészségtudományok Intézete</span> </div> </div> <div class="title"><a href="/gui2/?mode=browse&params=publication;30485260" target="_blank">Involvement of complement activation in the pulmonary vasoactivity of polystyrene nanoparticles in pigs: unique surface properties underlying alternative pathway activation and instant opsonization</a></div> <div> <span class="journal-title">INTERNATIONAL JOURNAL OF NANOMEDICINE</span> <span class="journal-issn">(<a target="_blank" href="https://portal.issn.org/resource/ISSN/1176-9114">1176-9114</a> <a target="_blank" href="https://portal.issn.org/resource/ISSN/1178-2013">1178-2013</a>)</span>: <span class="journal-volume">13</span> <span class="page"> pp 6345-6357 </span> <span class="year">(2018)</span> </div> <div class="pub-footer"> <span class="language" xmlns="http://www.w3.org/1999/html">Language: English | </span> <span class="identifiers"> <span class="id identifier oa_GOLD" title=" Gold "> <a style="color:blue" title="10.2147/IJN.S161369" target="_blank" href="https://doi.org/10.2147/IJN.S161369"> DOI </a> </span> <span class="id identifier oa_none" title="none"> <a style="color:blue" title="000447172400001" target="_blank" href="https://www.webofscience.com/wos/woscc/full-record/000447172400001"> WoS </a> </span> <span class="id identifier oa_none" title="none"> <a style="color:blue" title="85054355741" target="_blank" href="http://www.scopus.com/record/display.url?origin=inward&eid=2-s2.0-85054355741"> Scopus </a> </span> <span class="id identifier oa_none" title="none"> <a style="color:blue" title="30349254" target="_blank" href="http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db=PubMed&list_uids=30349254&dopt=Abstract"> PubMed </a> </span> </span> <OnlyViewableByAuthor><div class="ratings"> <div class="journal-subject">Journal subject: Scopus - Bioengineering&nbsp;&nbsp;&nbsp;Rank:&nbsp;Q1</div> <div class="journal-subject">Journal subject: Scopus - Biomaterials&nbsp;&nbsp;&nbsp;Rank:&nbsp;Q1</div> <div class="journal-subject">Journal subject: Scopus - Biophysics&nbsp;&nbsp;&nbsp;Rank:&nbsp;Q1</div> <div class="journal-subject">Journal subject: Scopus - Drug Discovery&nbsp;&nbsp;&nbsp;Rank:&nbsp;Q1</div> <div class="journal-subject">Journal subject: Scopus - Medicine (miscellaneous)&nbsp;&nbsp;&nbsp;Rank:&nbsp;Q1</div> <div class="journal-subject">Journal subject: Scopus - Organic Chemistry&nbsp;&nbsp;&nbsp;Rank:&nbsp;Q1</div> <div class="journal-subject">Journal subject: Scopus - Pharmaceutical Science&nbsp;&nbsp;&nbsp;Rank:&nbsp;Q1</div> <div class="journal-subject">Journal subject: Scopus - Nanoscience and Nanotechnology&nbsp;&nbsp;&nbsp;Rank:&nbsp;Q2</div> </div></OnlyViewableByAuthor> <div class="publication-citation" style="margin-left: 0.5cm;"> <span title="" class="citingPub-count">Citing papers: 27</span> | Independent citation: 13 | Self citation: 14 | Unknown citation: 0 | Number of citations in WoS: 25 | Number of citations in Scopus:&nbsp;24 | WoS/Scopus assigned:&nbsp;27 | Number of citations with DOI:&nbsp;26 </div> <div class="publication-citation"> <a target="_blank" href="/api/publication?cond=citations.related;eq;30485260&sort=publishedYear,desc&sort=title"> Number of cited publications: 14 </a> </div> <div class="mtid"><span class="long-pub-mtid">Publication: 30485260</span> | <span class="status-data status-VALIDATED"> Validated </span> Core Citing | <span class="type-subtype">Journal Article ( Article ) </span> | <span class="pub-category">Scientific</span> | <span class="publication-sourceOfData">WoS XML</span> </div> <div class="lastModified">Last Modified: 2022.11.21. 12:11 Márta Molnár-Taga (SE 4-es admin) </div> <pre class="comment" style="margin-top: 0; margin-bottom: 0;"><u>Comments</u>: Nanomedicine Research and Education Center, Department of Pathophysiology, Semmelweis University, Budapest, Hungary SeroScience Ltd, Budapest, Hungary Department of Pharmacokinetics and Biopharmaceutics, Institute of Biomedical Sciences, Tokushima University, Tokushima, Japan Laboratory of Membrane and Liposome Research, De...</pre> </div></div>