https://m2.mtmt.hu/ eng 2026-09-23 01:14 JournalArticle 30328907 VALIDATED true Cited By :21 Export Date: 22 March 2023 CODEN: MOLEF Correspondence Address: Mucsi, Z.; Department of Chemistry, Canada; email: zoltanmucsi@gmail.com 0 false 2026-09-12T14:34:46.496+0000 2026-05-19T08:10:27.777+0000 2018-11-26T11:58:47.040+0000 true 10065463 Turek Márta /api/admin/10065463 Admin true 2026-08-14T14:10:52.222+0000 2026-08-14T14:10:52.222+0000 2024-08-25T11:59:19.283+0000 true 10066925 Nemec Évi /api/admin/10066925 Admin true Admin 10013962 /api/admin/10013962 Vasvari Lilian true 10013962 true 2025-02-15T15:12:32.461+0000 true false true 24 24 /api/publicationtype/24 PublicationType 1 true 24 JournalArticle true 10000059 Article true 24 24 /api/publicationtype/24 PublicationType 1 true 24 JournalArticle /api/subtype/10000059 Szakcikk SubType 101 true 10000059 true 1 /api/category/1 Category true 1 Kovács, Ervin Amide Activation in Ground and Excited States true true /api/journal/25013 REVIEWED true false 25013 false 25013 true 1431-5157 1420-3049 Journal FOREIGN 23 11 2859 2859 31 2018 Not all amide bonds are created equally. The purpose of the present paper is the reinterpretation of the amide group by means of two concepts: amidicity and carbonylicity. These concepts are meant to provide a new viewpoint in defining the stability and reactivity of amides. With the help of simple quantum-chemical calculations, practicing chemists can easily predict the outcome of a desired process. The main benefit of the concepts is their simplicity. They provide intuitive, but quasi-thermodynamic data, making them a practical rule of thumb for routine use. In the current paper we demonstrate the performance of our methods to describe the chemical character of an amide bond strength and the way of its activation methods. Examples include transamidation, acyl transfer and amide reductions. Also, the method is highly capable for simple interpretation of mechanisms for biological processes, such as protein splicing and drug mechanisms. Finally, we demonstrate how these methods can provide information about photo-activation of amides, through the examples of two caged neurotransmitter derivatives. Funding 1971698 /api/funding/1971698 false true Funding 1971699 /api/funding/1971699 false true Funding 1971700 /api/funding/1971700 false true true NATIONAL 2018 true true true false true false GOLD 2026-09-12 true https://doi.org/10.3390/molecules23112859 56 0 48 40 8 49 49 43 41 44 44 36 36 48 8 0 56 48 48 40 0 9 9 Folyóiratcikk Journal Article 24 48 Könyvrészlet Chapter in Book 25 0 Könyv Book 23 0 Egyéb konferenciaközlemény Conference paper 31 0 Egyéb konferenciakötet Conference proceedings 32 0 Oltalmi formák Protection forms 26 0 Disszertáció Thesis 28 5 Egyéb Miscellaneous 29 3 Alkotás Achievement 22 0 Kutatási adat Research data 33 0 Folyóiratcikk Journal Article 24 0 0 0 Könyvrészlet Chapter in Book 25 0 0 0 Könyv Book 23 0 0 0 Egyéb konferenciaközlemény Conference paper 31 0 0 0 Egyéb konferenciakötet Conference proceedings 32 0 0 0 Oltalmi formák Protection forms 26 0 0 0 Disszertáció Thesis 28 0 0 0 Egyéb Miscellaneous 29 0 0 0 Alkotás Achievement 22 0 0 0 Kutatási adat Research data 33 0 0 0 2018 0 1 1 1 1 2019 0 4 3 4 3 2020 0 8 8 8 8 2021 0 8 7 8 7 2022 0 8 6 8 6 2023 0 5 3 5 3 2024 0 5 4 5 4 2025 0 8 7 8 7 2026 0 9 9 9 9 Q1 false 10030581,10042935 false false false 2019-02-13T14:30:22.953+0000 2019-01-09T12:06:18.944+0000 Akadémikus bibliográfia; Anyag- és Környezetkémiai Intézet (TTK); Femtonics Kutató és Fejlesztő Korlátolt Felelős...; Neuronhálózat és Dendritikus Aktivitás Kutatócs... (HRN KOKI); Szerves Kémia és Technológia Tanszék (BME / VBK); TTK hallgatók (ELTE / TTK); Zöldkémia Kutatócsoport (HRN TTK / AKI) 5 48 7 5 0 true 10013962 Language 10002 /api/language/10002 Angol English true 2 true PersonAuthorship 86585556 /api/authorship/86585556 1 0.2 true false Author 10030581 /api/author/10030581 Kovács Ervin true 10030581 true Kovács Ervin true false false AuthorshipType 1 /api/authorshiptype/1 0 true 0 true false true PersonAuthorship 84413573 /api/authorship/84413573 2 0.2 false false Author 10012926 /api/author/10012926 Rózsa J. Balázs true 10012926 true Rózsa Balázs true false false AuthorshipType 1 /api/authorshiptype/1 0 true 0 true false true PersonAuthorship 84413574 /api/authorship/84413574 3 0.2 false false Author 10068523 /api/author/10068523 Csomos Attila true true Csomos Attila true false false AuthorshipType 1 /api/authorshiptype/1 0 true 0 true false true PersonAuthorship 84413575 /api/authorship/84413575 4 0.2 false false Author 10011269 /api/author/10011269 Csizmadia Imre Gyula true 10011269 true Csizmadia Imre true false false AuthorshipType 1 /api/authorshiptype/1 0 true 0 true false true PersonAuthorship 86585559 /api/authorship/86585559 5 0.2 false true true Author 10042935 /api/author/10042935 Mucsi Zoltán true 10042935 true Mucsi Zoltán true false false AuthorshipType 1 /api/authorshiptype/1 0 true 0 true false true Institute 19040 /api/institute/19040 0 false false true Akadémikus bibliográfia Bibliografy of Hungarian of Academy of Sciences' academicians true 19040 true PublicationIdentifier 14625541 /api/publicationidentifier/14625541 PlainSource 6 /api/publicationsource/6 PublicationSourceType 10001 /api/publicationsourcetype/10001 true true true DOI DOI https://doi.org/@@@ true true 6 true GOLD true IDENTICAL 10.3390/molecules23112859 https://doi.org/10.3390/molecules23112859 false true PublicationIdentifier 15191799 /api/publicationidentifier/15191799 PlainSource 1 /api/publicationsource/1 PublicationSourceType 10003 /api/publicationsourcetype/10003 false true true WoS WoS https://www.webofscience.com/wos/woscc/full-record/@@@ true true 1 true IDENTICAL 000451641900131 https://www.webofscience.com/wos/woscc/full-record/000451641900131 false true PublicationIdentifier 20982854 /api/publicationidentifier/20982854 SwordSource 92 /api/publicationsource/92 PublicationSourceType 10007 /api/publicationsourcetype/10007 true true true EDIT EDIT https://edit.elte.hu/handle/10831/@@@ true true 92 true GREEN true 67128 https://edit.elte.hu/handle/10831/67128 false true PublicationIdentifier 15063462 /api/publicationidentifier/15063462 PlainSource 3 /api/publicationsource/3 PublicationSourceType 10003 /api/publicationsourcetype/10003 false true true Scopus Scopus http://www.scopus.com/record/display.url?origin=inward&eid=2-s2.0-@@@ true true 3 true IDENTICAL 85056278972 http://www.scopus.com/record/display.url?origin=inward&eid=2-s2.0-85056278972 false true PublicationIdentifier 15151865 /api/publicationidentifier/15151865 PlainSource 17 /api/publicationsource/17 PublicationSourceType 10003 /api/publicationsourcetype/10003 false true true PubMed PubMed http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db=PubMed&list_uids=@@@&dopt=Abstract true true 17 true IDENTICAL 30400217 http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db=PubMed&list_uids=30400217&dopt=Abstract false true PublicationIdentifier 14625542 /api/publicationidentifier/14625542 PlainSource 40 /api/publicationsource/40 PublicationSourceType 10006 /api/publicationsourcetype/10006 true true true Egyéb URL Other URL @@@ true true 40 true http://www.mdpi.com/1420-3049/23/11/2859 http://www.mdpi.com/1420-3049/23/11/2859 false true SjrRating 10762820 /api/sjrrating/10762820 100 0.24 journal RatingType 10002 /api/ratingtype/10002 sjr true true ClassificationExternal 1601 /api/classificationexternal/1601 true 1601 true Q1 DIRECT true true /api/publication/30328907 <div class="JournalArticle Publication long-list"> <div class="authors"> <img title="Forrásközlemény" style="float: left" src="/frontend/resources/grid/publication-core-icon.png"> <img title="Idézőközlemény" style="float: left" src="/frontend/resources/grid/publication-citation-icon.png"> <div class="autype autype0"> <span class="author-name" mtid="10030581"><a href="/gui2/?type=authors&mode=browse&sel=10030581" target="_blank">Kovács Ervin (<span class="authorship-author-name">Kovács Ervin</span> <span class="authorAux-mtmt"> Szerves kémia</span>) </a> </span> <span class="author-affil"><span title="Research Centre for Natural Sciences">RCNS</span>/Institute of Materials and Environmental Chemistry; <span title="MTA Research Centre for Natural Sciences">MTA TTK</span>/<span title="Institute of Materials and Environmental Chemistry">IMEC</span>/Zöldkémia Kutatócsoport</span> ;&nbsp;&nbsp;&nbsp; <span class="author-name" mtid="10012926"><a href="/gui2/?type=authors&mode=browse&sel=10012926" target="_blank">Rózsa Balázs (<span class="authorship-author-name">Rózsa J. Balázs</span> <span class="authorAux-mtmt"> Idegtudomány, fizika</span>) </a> </span> <span class="author-affil"><span title="MTA Kísérleti Orvostudományi Kutatóintézet">IEMHAS</span>/<span title="Department of Pharmacology">DP</span>/Neuronhálózat és Dendritikus Aktivitás Kutatócsoport</span> ;&nbsp;&nbsp;&nbsp; <span class="author-name" mtid="10068523"><a href="/gui2/?type=authors&mode=browse&sel=10068523" target="_blank">Csomos Attila (<span class="authorship-author-name">Csomos Attila</span> <span class="authorAux-mtmt"> Kémia</span>) </a> </span> <span class="author-affil"><span title="Eötvös Loránd University">ELTE</span>/<span title="Faculty of Science">ELU FoS</span>/TTK students</span> ;&nbsp;&nbsp;&nbsp; <span class="author-name" mtid="10011269"><a href="/gui2/?type=authors&mode=browse&sel=10011269" target="_blank">Csizmadia Imre (<span class="authorship-author-name">Csizmadia Imre Gyula</span> <span class="authorAux-mtmt"> elméleti szerves kémia, természetes vegyületek ...</span>) </a> </span> ;&nbsp;&nbsp;&nbsp; <span class="author-name" mtid="10042935"><a href="/gui2/?type=authors&mode=browse&sel=10042935" target="_blank">Mucsi Zoltán ✉ (<span class="authorship-author-name">Mucsi Zoltán</span> <span class="authorAux-mtmt"> szerves kémia</span>) </a> </span> <span class="author-affil"><span title="Budapest University of Technology and Economics">BUTE</span>/<span title="Faculty of Chemical Technology and Biotechnology">FCTB</span>/Department of Organic Chemistry and Technology; Femtonics Ltd.</span> </div> </div> <div class="title"><a href="/gui2/?mode=browse&params=publication;30328907" target="_blank">Amide Activation in Ground and Excited States</a></div> <div> <span class="journal-title">MOLECULES</span> <span class="journal-issn">(<a target="_blank" href="https://portal.issn.org/resource/ISSN/1431-5157">1431-5157</a> <a target="_blank" href="https://portal.issn.org/resource/ISSN/1420-3049">1420-3049</a>)</span>: <span class="journal-volume">23</span> <span class="journal-issue">11</span> <span class="page"> Paper 2859. 31 p. </span> <span class="year">(2018)</span> </div> <div class="pub-footer"> <span class="language" xmlns="http://www.w3.org/1999/html">Language: English | </span> <span class="identifiers"> <span class="id identifier oa_GOLD" title=" Gold "> <a style="color:blue" title="10.3390/molecules23112859" target="_blank" href="https://doi.org/10.3390/molecules23112859"> DOI </a> </span> <span class="id identifier oa_none" title="none"> <a style="color:blue" title="000451641900131" target="_blank" href="https://www.webofscience.com/wos/woscc/full-record/000451641900131"> WoS </a> </span> <span class="id identifier oa_GREEN" title=" Green "> <a style="color:black" title="67128" target="_blank" href="https://edit.elte.hu/handle/10831/67128"> EDIT </a> </span> <span class="id identifier oa_none" title="none"> <a style="color:blue" title="85056278972" target="_blank" href="http://www.scopus.com/record/display.url?origin=inward&eid=2-s2.0-85056278972"> Scopus </a> </span> <span class="id identifier oa_none" title="none"> <a style="color:blue" title="30400217" target="_blank" href="http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db=PubMed&list_uids=30400217&dopt=Abstract"> PubMed </a> </span> <span class="id identifier oa_none" title="none"> <a style="color:black" title="http://www.mdpi.com/1420-3049/23/11/2859" target="_blank" href="http://www.mdpi.com/1420-3049/23/11/2859"> Other URL </a> </span> </span> <OnlyViewableByAuthor><div class="ratings"> <div class="journal-subject">Journal subject: Scopus - Chemistry (miscellaneous)&nbsp;&nbsp;&nbsp;Rank:&nbsp;Q1</div> <div class="journal-subject">Journal subject: Scopus - Pharmaceutical Science&nbsp;&nbsp;&nbsp;Rank:&nbsp;Q1</div> <div class="journal-subject">Journal subject: Scopus - Analytical Chemistry&nbsp;&nbsp;&nbsp;Rank:&nbsp;Q2</div> <div class="journal-subject">Journal subject: Scopus - Drug Discovery&nbsp;&nbsp;&nbsp;Rank:&nbsp;Q2</div> <div class="journal-subject">Journal subject: Scopus - Medicine (miscellaneous)&nbsp;&nbsp;&nbsp;Rank:&nbsp;Q2</div> <div class="journal-subject">Journal subject: Scopus - Organic Chemistry&nbsp;&nbsp;&nbsp;Rank:&nbsp;Q2</div> <div class="journal-subject">Journal subject: Scopus - Physical and Theoretical Chemistry&nbsp;&nbsp;&nbsp;Rank:&nbsp;Q2</div> <div class="journal-subject">Journal subject: Scopus - Molecular Medicine&nbsp;&nbsp;&nbsp;Rank:&nbsp;Q3</div> </div></OnlyViewableByAuthor> <div class="publication-citation" style="margin-left: 0.5cm;"> <span title="" class="citingPub-count">Citing papers: 56</span> | Independent citation: 48 | Self citation: 8 | Unknown citation: 0 | Number of citations in WoS: 43 | Number of citations in Scopus:&nbsp;41 | WoS/Scopus assigned:&nbsp;44 | Number of citations with DOI:&nbsp;49 </div> <div class="publication-citation"> <a target="_blank" href="/api/publication?cond=citations.related;eq;30328907&sort=publishedYear,desc&sort=title"> Number of cited publications: 9 </a> </div> <div class="mtid"><span class="long-pub-mtid">Publication: 30328907</span> | <span class="status-data status-VALIDATED"> Validated </span> Core Citing | <span class="type-subtype">Journal Article ( Article ) </span> | <span class="pub-category">Scientific</span> | <span class="publication-sourceOfData">kézi felvitel</span> </div> <div class="special-affiliations"> Special affiliation: Bibliografy of Hungarian of Academy of Sciences' academicians </div> <div class="funder"> (KFI_16-1-2016-0177), (NVKP_16-1-2016-0043), (OTKA PD128612) Funder: NRDIO </div> <div class="notDuplums"><a target="_blank" href="/api/publication/30328907/notduplums">4 marked as not duplum</a> </div> <div class="lastModified">Last Modified: 2026.05.19. 10:10 Fruzsina Háromszéki-Virág (MTMT Központi admin) </div> <div class="lockedBy">Centrally managed 2025.02.15. 16:12 Lilian Vasvari (MTMT Központ, admin) </div> <pre class="comment" style="margin-top: 0; margin-bottom: 0;"><u>Comments</u>: Cited By :21 Export Date: 22 March 2023 CODEN: MOLEF Correspondence Address: Mucsi, Z.; Department of Chemistry, Canada; email: zoltanmucsi@gmail.com</pre> </div></div>