https://m2.mtmt.hu/ eng 2026-04-21 10:44 JournalArticle 30309774 VALIDATED true 0 false 2026-04-13T09:53:07.030+0000 2024-11-25T13:37:17.370+0000 2018-11-06T13:12:38.316+0000 true 10037665 Bilicsi Erika /api/admin/10037665 Admin Erika Bilicsi (KOKI admin 4) true 10037665 2025-04-17T07:11:23.683+0000 2025-04-17T07:11:23.683+0000 2019-02-14T14:30:16.617+0000 true 10065569 Pécsi Éva /api/admin/10065569 Admin Éva Pécsi (MTMT Közp 2,3, admin) true 2024-11-25T13:37:17.676+0000 true 10003134 Wolf György /api/admin/10003134 Admin György Wolf (MTMT Központi admin) true 10003134 Admin 10003134 /api/admin/10003134 György Wolf (MTMT Központi admin) Wolf György true 10003134 true Admin 10067876 /api/admin/10067876 Gusztáv Ladányi (MTMT API user, admin) Ladányi Gusztáv true true 2024-10-17T16:42:14.442+0000 true false true 24 24 /api/publicationtype/24 PublicationType Journal Article 1 true 24 JournalArticle true 10000059 Article true 24 24 /api/publicationtype/24 PublicationType Journal Article 1 true 24 JournalArticle /api/subtype/10000059 Szakcikk SubType Article (Journal Article) 101 true 10000059 true 1 /api/category/1 Category Scientific true 1 Mátyás, F. true true /api/journal/19517 REVIEWED NATURE NEUROSCIENCE 1097-6256 1546-1726 true false 19517 false 19517 true 1097-6256 1546-1726 Journal FOREIGN 21 11 1551 1562 1551 12 2018 Sleep cycles consist of rapid alterations between arousal states, including transient perturbation of sleep rhythms, microarousals, and full-blown awake states. Here we demonstrate that the calretinin (CR)-containing neurons in the dorsal medial thalamus (DMT) constitute a key diencephalic node that mediates distinct levels of forebrain arousal. Cell-type-specific activation of DMT/CR+ cells elicited active locomotion lasting for minutes, stereotyped microarousals, or transient disruption of sleep rhythms, depending on the parameters of the stimulation. State transitions could be induced in both slow-wave and rapid eye-movement sleep. The DMT/CR+ cells displayed elevated activity before arousal, received selective subcortical inputs, and innervated several forebrain sites via highly branched axons. Together, these features enable DMT/CR+ cells to summate subcortical arousal information and effectively transfer it as a rapid, synchronous signal to several forebrain regions to modulate the level of arousal. © 2018, The Author(s), under exclusive licence to Springer Nature America, Inc. Funding 1995343 /api/funding/1995343 PD(124034) false true Funding 1995344 /api/funding/1995344 (NKTH-ANR-09-BLAN-0401) false true true true 2018 true true true false true false PAY 2026-04-13 false 67 0 67 58 12 67 66 62 62 67 67 58 58 58 9 0 67 58 67 58 0 6 6 Folyóiratcikk Journal Article 24 66 Könyvrészlet Chapter in Book 25 1 Könyv Book 23 0 Egyéb konferenciaközlemény Conference paper 31 0 Egyéb konferenciakötet Conference proceedings 32 0 Oltalmi formák Protection forms 26 0 Disszertáció Thesis 28 0 Egyéb Miscellaneous 29 0 Alkotás Achievement 22 0 Kutatási adat Research data 33 0 Folyóiratcikk Journal Article 24 0 0 0 Könyvrészlet Chapter in Book 25 0 0 0 Könyv Book 23 0 0 0 Egyéb konferenciaközlemény Conference paper 31 0 0 0 Egyéb konferenciakötet Conference proceedings 32 0 0 0 Oltalmi formák Protection forms 26 0 0 0 Disszertáció Thesis 28 0 0 0 Egyéb Miscellaneous 29 0 0 0 Alkotás Achievement 22 0 0 0 Kutatási adat Research data 33 0 0 0 2018 0 1 1 1 1 2019 0 8 8 8 8 2020 0 6 5 6 5 2021 0 9 9 9 9 2022 0 13 10 13 10 2023 0 13 11 13 11 2024 0 2 2 2 2 2025 0 15 12 15 12 D1 false 176,10009548,10013576,10058708,10018448,163,10052373 false false false 2018-11-05T13:31:59.601+0000 2018-11-06T13:31:59.597+0000 Anatómiai, Szövet- és Fejlődéstani Intézet (SE / AOK / I); Doktori Iskola (SE); Kognitív Idegtudományi és Pszichológiai Intézet (HRN TTK); MTA-TTK-NAP B Hálózat és Viselkedés Neurobiológ... (HRN TTK / KPI); Roska Tamás Műszaki és Természettudományi Dokto... (PPKE / ITK); Thalamus Kutatócsoport (HRN KOKI) 10 51 6 13 0 true 10003134 10067876 Language 10002 /api/language/10002 English Angol English true 2 true PersonAuthorship 84237375 /api/authorship/84237375 Mátyás, F. ✉ [Mátyás, Ferenc (Neurobiológia), author] Institute of Cognitive Neuroscience and Psychology; Laboratory of Thalamus Research 1 0.07692308 true false true Author 163 /api/author/163 Ferenc Mátyás (Neurobiológia) Mátyás Ferenc true 163 true Mátyás F. true false false AuthorshipType 1 /api/authorshiptype/1 Author 0 true 0 true false true PersonAuthorship 84237376 /api/authorship/84237376 Komlósi, G. [Komlósi, Gergely (idegtudomány), author] Laboratory of Thalamus Research 2 0.077 false false Author 10033176 /api/author/10033176 Gergely Komlósi (idegtudomány) Komlósi Gergely true 10033176 true Komlósi G. true false false AuthorshipType 1 /api/authorshiptype/1 Author 0 true 0 true false true PersonAuthorship 84237377 /api/authorship/84237377 Babiczky, Á. [Babiczky, Ákos (Neurobiológia, ps...), author] Institute of Cognitive Neuroscience and Psychology 3 0.077 false false Author 10054911 /api/author/10054911 Ákos Babiczky (Neurobiológia, pszichológiai és kognitív tudományok) Babiczky Ákos true 10054911 true Babiczky Á. true false false AuthorshipType 1 /api/authorshiptype/1 Author 0 true 0 true false true PersonAuthorship 84237378 /api/authorship/84237378 Kocsis, K. [Kocsis, Kinga (biológia), author] Roska Tamás Műszaki és Természettudományi Dokto... (PPCU / ITK); MTA-TTK-NAP B Neuronal Network and Behaviour Re... (KPI) 4 0.07692308 false false Author 10052373 /api/author/10052373 Kinga Kocsis (biológia) Kocsis Kinga true 10052373 true Kocsis K. true false false AuthorshipType 1 /api/authorshiptype/1 Author 0 true 0 true false true PersonAuthorship 84237379 /api/authorship/84237379 Barthó, P. [Barthó, Péter (Idegélettan), author] Laboratory of Thalamus Research 5 0.077 false false Author 10013576 /api/author/10013576 Péter Barthó (Idegélettan) Barthó Péter true 10013576 true Barthó P. true false false AuthorshipType 1 /api/authorshiptype/1 Author 0 true 0 true false true PersonAuthorship 84237380 /api/authorship/84237380 Barsy, B. [Barsy, Boglárka (Idegélettan), author] MTA-TTK-NAP B Neuronal Network and Behaviour Re... (KPI) 6 0.07692308 false false Author 176 /api/author/176 Boglárka Barsy (Idegélettan) Barsy Boglárka true 176 true Barsy B. true false false AuthorshipType 1 /api/authorshiptype/1 Author 0 true 0 true false true PersonAuthorship 84237381 /api/authorship/84237381 Dávid, C. [Dávid, Csaba (idegrendszer), author] Anatómiai, Szövet- és Fejlődéstani Intézet (SU / FM / I) 7 0.07692308 false false Author 10018448 /api/author/10018448 Csaba Dávid (idegrendszer) Dávid Csaba true 10018448 true Dávid C. true false false AuthorshipType 1 /api/authorshiptype/1 Author 0 true 0 true false true PersonAuthorship 84237382 /api/authorship/84237382 Kanti, V. [Kanti, Vivien Ildikó (neurobiológia), author] School of Ph. D. Studies (SU) 8 0.07692308 false false Author 10054416 /api/author/10054416 Vivien Ildikó Kanti (neurobiológia) Kanti Vivien Ildikó true 10054416 true Kanti V. true false false AuthorshipType 1 /api/authorshiptype/1 Author 0 true 0 true false true PersonAuthorship 84237383 /api/authorship/84237383 Porrero, C. 9 0.07692308 false false Porrero C. true false false AuthorshipType 1 /api/authorshiptype/1 Author 0 true 0 true false true PersonAuthorship 84237384 /api/authorship/84237384 Magyar, A. [Magyar, Aletta (neurobiológia), author] Institute of Cognitive Neuroscience and Psychology; School of Ph. D. Studies (SU); MTA-TTK-NAP B Neuronal Network and Behaviour Re... (KPI) 10 0.07692308 false false Author 10058708 /api/author/10058708 Aletta Magyar (neurobiológia) Magyar Aletta true 10058708 true Magyar A. true false false AuthorshipType 1 /api/authorshiptype/1 Author 0 true 0 true false true PersonAuthorship 84237385 /api/authorship/84237385 Szűcs, I. 11 0.07692308 false false Szűcs I. true false false AuthorshipType 1 /api/authorshiptype/1 Author 0 true 0 true false true PersonAuthorship 84237386 /api/authorship/84237386 Clasca, F. 12 0.07692308 false false Clasca F. true false false AuthorshipType 1 /api/authorshiptype/1 Author 0 true 0 true false true PersonAuthorship 84237387 /api/authorship/84237387 Acsády, L. ✉ [Acsády, László (Neurobiológia), author] Laboratory of Thalamus Research 13 0.07692308 false true true Author 10009548 /api/author/10009548 László Acsády (Neurobiológia) Acsády László true 10009548 true Acsády L. true false false AuthorshipType 1 /api/authorshiptype/1 Author 0 true 0 true false true PublicationIdentifier 14595842 /api/publicationidentifier/14595842 DOI: 10.1038/s41593-018-0251-9 PlainSource 6 /api/publicationsource/6 DOI PublicationSourceType 10001 /api/publicationsourcetype/10001 DOI true true true DOI DOI https://doi.org/@@@ true true 6 true PAY IDENTICAL 10.1038/s41593-018-0251-9 https://doi.org/10.1038/s41593-018-0251-9 false true PublicationIdentifier 15118690 /api/publicationidentifier/15118690 WoS: 000448319500009 PlainSource 1 /api/publicationsource/1 WoS PublicationSourceType 10003 /api/publicationsourcetype/10003 Indexelő adatbázis false true true WoS WoS https://www.webofscience.com/wos/woscc/full-record/@@@ true true 1 true IDENTICAL 000448319500009 https://www.webofscience.com/wos/woscc/full-record/000448319500009 true true PublicationIdentifier 15821581 /api/publicationidentifier/15821581 Scopus: 85055463554 PlainSource 3 /api/publicationsource/3 Scopus PublicationSourceType 10003 /api/publicationsourcetype/10003 Indexelő adatbázis false true true Scopus Scopus http://www.scopus.com/record/display.url?origin=inward&eid=2-s2.0-@@@ true true 3 true IDENTICAL 85055463554 http://www.scopus.com/record/display.url?origin=inward&eid=2-s2.0-85055463554 false true PublicationIdentifier 15159672 /api/publicationidentifier/15159672 PubMed: 30349105 PlainSource 17 /api/publicationsource/17 PubMed PublicationSourceType 10003 /api/publicationsourcetype/10003 Indexelő adatbázis false true true PubMed PubMed http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db=PubMed&list_uids=@@@&dopt=Abstract true true 17 true IDENTICAL 30349105 http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db=PubMed&list_uids=30349105&dopt=Abstract false true SjrRating 10862636 /api/sjrrating/10862636 sjr:D1 (2018) Scopus - Neuroscience (miscellaneous) NATURE NEUROSCIENCE 1097-6256 1546-1726 2 0.1 journal RatingType 10002 /api/ratingtype/10002 sjr sjr true true ClassificationExternal 2801 /api/classificationexternal/2801 Scopus - Neuroscience (miscellaneous) true 2801 true D1 DIRECT true true /api/publication/30309774 Mátyás F. et al. A highly collateralized thalamic cell type with arousal-predicting activity serves as a key hub for graded state transitions in the forebrain. (2018) NATURE NEUROSCIENCE 1097-6256 1546-1726 21 11 1551-1562<div class="JournalArticle Publication long-list"> <div class="authors"> <img title="Forrásközlemény" style="float: left" src="/frontend/resources/grid/publication-core-icon.png"> <img title="Idézőközlemény" style="float: left" src="/frontend/resources/grid/publication-citation-icon.png"> <div class="autype autype0"> <span class="author-name" mtid="163"><a href="/gui2/?type=authors&mode=browse&sel=163" target="_blank">Mátyás F. ✉ (<span class="authorship-author-name">Mátyás Ferenc</span> <span class="authorAux-mtmt"> Neurobiológia</span>) </a> </span> <span class="author-affil"><span title="MTA Research Centre for Natural Sciences">MTA TTK</span>/Institute of Cognitive Neuroscience and Psychology; <span title="MTA Kísérleti Orvostudományi Kutatóintézet">IEMHAS</span>/<span title="Department of Cellular and Network Neurobiology">DCNN</span>/Laboratory of Thalamus Research</span> ;&nbsp;&nbsp;&nbsp; <span class="author-name" mtid="10033176"><a href="/gui2/?type=authors&mode=browse&sel=10033176" target="_blank">Komlósi G. (<span class="authorship-author-name">Komlósi Gergely</span> <span class="authorAux-mtmt"> idegtudomány</span>) </a> </span> <span class="author-affil"><span title="MTA Kísérleti Orvostudományi Kutatóintézet">IEMHAS</span>/<span title="Department of Cellular and Network Neurobiology">DCNN</span>/Laboratory of Thalamus Research</span> ;&nbsp;&nbsp;&nbsp; <span class="author-name" mtid="10054911"><a href="/gui2/?type=authors&mode=browse&sel=10054911" target="_blank">Babiczky Á. (<span class="authorship-author-name">Babiczky Ákos</span> <span class="authorAux-mtmt"> Neurobiológia, pszichológiai és kognitív tudomá...</span>) </a> </span> <span class="author-affil"><span title="MTA Research Centre for Natural Sciences">MTA TTK</span>/Institute of Cognitive Neuroscience and Psychology</span> ;&nbsp;&nbsp;&nbsp; <span class="author-name" mtid="10052373"><a href="/gui2/?type=authors&mode=browse&sel=10052373" target="_blank">Kocsis K. (<span class="authorship-author-name">Kocsis Kinga</span> <span class="authorAux-mtmt"> biológia</span>) </a> </span> <span class="author-affil"><span title="Pázmány Péter Catholic University">PPCU</span>/<span title="Információs Technológiai és Bionikai Kar">ITK</span>/Roska Tamás Műszaki és Természettudományi Doktori Iskola; <span title="MTA Research Centre for Natural Sciences">MTA TTK</span>/<span title="Institute of Cognitive Neuroscience and Psychology">KPI</span>/MTA-TTK-NAP B Neuronal Network and Behaviour Research Group</span> ;&nbsp;&nbsp;&nbsp; <span class="author-name" mtid="10013576"><a href="/gui2/?type=authors&mode=browse&sel=10013576" target="_blank">Barthó P. (<span class="authorship-author-name">Barthó Péter</span> <span class="authorAux-mtmt"> Idegélettan</span>) </a> </span> <span class="author-affil"><span title="MTA Kísérleti Orvostudományi Kutatóintézet">IEMHAS</span>/<span title="Department of Cellular and Network Neurobiology">DCNN</span>/Laboratory of Thalamus Research</span> ;&nbsp;&nbsp;&nbsp; <span class="author-name" mtid="176"><a href="/gui2/?type=authors&mode=browse&sel=176" target="_blank">Barsy B. (<span class="authorship-author-name">Barsy Boglárka</span> <span class="authorAux-mtmt"> Idegélettan</span>) </a> </span> <span class="author-affil"><span title="MTA Research Centre for Natural Sciences">MTA TTK</span>/<span title="Institute of Cognitive Neuroscience and Psychology">KPI</span>/MTA-TTK-NAP B Neuronal Network and Behaviour Research Group</span> ;&nbsp;&nbsp;&nbsp; <span class="author-name" mtid="10018448"><a href="/gui2/?type=authors&mode=browse&sel=10018448" target="_blank">Dávid C. (<span class="authorship-author-name">Dávid Csaba</span> <span class="authorAux-mtmt"> idegrendszer</span>) </a> </span> <span class="author-affil"><span title="Semmelweis University">SU</span>/<span title="Faculty of Medicine">FM</span>/<span title="Instituties">I</span>/Anatómiai, Szövet- és Fejlődéstani Intézet</span> ;&nbsp;&nbsp;&nbsp; <span class="author-name" mtid="10054416"><a href="/gui2/?type=authors&mode=browse&sel=10054416" target="_blank">Kanti V. (<span class="authorship-author-name">Kanti Vivien Ildikó</span> <span class="authorAux-mtmt"> neurobiológia</span>) </a> </span> <span class="author-affil"><span title="Semmelweis University">SU</span>/School of Ph. D. Studies</span> ;&nbsp;&nbsp;&nbsp; <span class="author-name" >Porrero C. </span> ;&nbsp;&nbsp;&nbsp; <span class="author-name" mtid="10058708"><a href="/gui2/?type=authors&mode=browse&sel=10058708" target="_blank">Magyar A. (<span class="authorship-author-name">Magyar Aletta</span> <span class="authorAux-mtmt"> neurobiológia</span>) </a> </span> <span class="author-affil"><span title="MTA Research Centre for Natural Sciences">MTA TTK</span>/Institute of Cognitive Neuroscience and Psychology; <span title="Semmelweis University">SU</span>/School of Ph. D. Studies; <span title="MTA Research Centre for Natural Sciences">MTA TTK</span>/<span title="Institute of Cognitive Neuroscience and Psychology">KPI</span>/MTA-TTK-NAP B Neuronal Network and Behaviour Research Group</span> ;&nbsp;&nbsp;&nbsp; <span class="author-name" >Szűcs I. </span> ;&nbsp;&nbsp;&nbsp; <span class="author-name" >Clasca F. </span> ;&nbsp;&nbsp;&nbsp; <span class="author-name" mtid="10009548"><a href="/gui2/?type=authors&mode=browse&sel=10009548" target="_blank">Acsády L. ✉ (<span class="authorship-author-name">Acsády László</span> <span class="authorAux-mtmt"> Neurobiológia</span>) </a> </span> <span class="author-affil"><span title="MTA Kísérleti Orvostudományi Kutatóintézet">IEMHAS</span>/<span title="Department of Cellular and Network Neurobiology">DCNN</span>/Laboratory of Thalamus Research</span> </div> </div> <div class="title"><a href="/gui2/?mode=browse&params=publication;30309774" target="_blank">A highly collateralized thalamic cell type with arousal-predicting activity serves as a key hub for graded state transitions in the forebrain</a></div> <div> <span class="journal-title">NATURE NEUROSCIENCE</span> <span class="journal-issn">(<a target="_blank" href="https://portal.issn.org/resource/ISSN/1097-6256">1097-6256</a> <a target="_blank" href="https://portal.issn.org/resource/ISSN/1546-1726">1546-1726</a>)</span>: <span class="journal-volume">21</span> <span class="journal-issue">11</span> <span class="page"> pp 1551-1562 </span> <span class="year">(2018)</span> </div> <div class="pub-footer"> <span class="language" xmlns="http://www.w3.org/1999/html">Language: English | </span> <span class="identifiers"> <span class="id identifier oa_PAY" title=" Pay "> <a style="color:blue" title="10.1038/s41593-018-0251-9" target="_blank" href="https://doi.org/10.1038/s41593-018-0251-9"> DOI </a> </span> <span class="id identifier oa_none" title="none"> <a style="color:blue" title="000448319500009" target="_blank" href="https://www.webofscience.com/wos/woscc/full-record/000448319500009"> WoS </a> </span> <span class="id identifier oa_none" title="none"> <a style="color:blue" title="85055463554" target="_blank" href="http://www.scopus.com/record/display.url?origin=inward&eid=2-s2.0-85055463554"> Scopus </a> </span> <span class="id identifier oa_none" title="none"> <a style="color:blue" title="30349105" target="_blank" href="http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db=PubMed&list_uids=30349105&dopt=Abstract"> PubMed </a> </span> </span> <OnlyViewableByAuthor><div class="ratings"> <div class="journal-subject">Journal subject: Scopus - Neuroscience (miscellaneous)&nbsp;&nbsp;&nbsp;Rank:&nbsp;D1</div> </div></OnlyViewableByAuthor> <div class="publication-citation" style="margin-left: 0.5cm;"> <span title="" class="citingPub-count">Citing papers: 67</span> | Independent citation: 58 | Self citation: 9 | Unknown citation: 0 | Number of citations in WoS: 62 | Number of citations in Scopus:&nbsp;62 | WoS/Scopus assigned:&nbsp;67 | Number of citations with DOI:&nbsp;66 </div> <div class="publication-citation"> <a target="_blank" href="/api/publication?cond=citations.related;eq;30309774&sort=publishedYear,desc&sort=title"> Number of cited publications: 6 </a> </div> <div class="mtid"><span class="long-pub-mtid">Publication: 30309774</span> | <span class="status-data status-VALIDATED"> Validated </span> Core Citing | <span class="type-subtype">Journal Article ( Article ) </span> | <span class="pub-category">Scientific</span> | <span class="publication-sourceOfData">Scopus (scopus (3).ris, 2018-11-06)</span> </div> <div class="funder"> PD(124034), (NKTH-ANR-09-BLAN-0401) </div> <div class="lastModified">Last Modified: 2024.11.25. 14:37 György Wolf (MTMT Központi admin) </div> <div class="lockedBy">Centrally managed 2024.10.17. 18:42 György Wolf (MTMT Központi admin) Gusztáv Ladányi (MTMT API user, admin) </div> </div></div>