Background: The authors analyzed data from the Hungarian Myocardial Infarction Registry
(HUMIR) to examine the potential impact of gender on the treatment and 30-day and
1-year mortality of patients with myocardial infarction (MI). Materials and Methods:
The National Registry of Myocardial Infarction included 42,953 patients between January
1, 2013 and December 31, 2016; 19,875 of whom were diagnosed with ST-elevation myocardial
infarction (STEMI) and 23,078 with non-ST-elevation myocardial infarction (NSTEMI).
The proportion of women was 39% and 41.9% in the two groups, respectively. Logistic
regression analysis was performed adjusting for age, the year and month of hospital
admission, smoking, as well as for five concomitant diseases and anamnestic data.
We found that the odds ratio (OR) of performing percutaneous coronary intervention
(PCI) was influenced by age, the year of treatment, prior stroke, and peripheral artery
disease (PAD) in both patient groups. Results: Gender had an impact on treatment in
both cases; women had significantly fewer PCIs (OR = 0.86 confidence interval [95%
CI: 0.77-0.95] in the STEMI group, OR = 0.75 [95% CI: 0.70-0.82] in the NSTEMI group).
Age and PCI, PAD, and diabetes mellitus proved to be prognostic factors for 30-day
and 1-year mortality in both groups. In the STEMI group, hypertension proved to be
of prognostic value for both 30-day and 1-year mortality, whereas prior MI, stroke,
and smoking only affected 1-year mortality. Similarly, in the NSTEMI group, prior
stroke was also of prognostic value for 30-day and 1-year mortality, whereas prior
MI, hypertension and smoking were only associated with 1-year mortality. Conclusions:
The independent prognostic value of gender could not be proven for any of the MI types
or follow-up periods. In conclusion, gender influenced the treatment of patients with
MI but had no significant impact on prognosis in itself.
