Microarray deals with DNA samples. It is a device that cotains an array of microscopic
glass slides coated with DNA molecules. Of late, it has evolved into hign density
DNA chip. Using this microarray, expressions of genes are measured using the laser
spectroscopic technique. We will not go into the details of the microarrray technology.
Rather, we will go into details of analysis of measured data for gene expression.
What do we get out of this analysis of minute DNA samples? How reliable is the information
extracted from this analysis? These are the puzzling questions that concern everyone
involved in biology and bioinformatics. In this chapter, we will discuss several analytical
techniques and tools used in image analysis of microarray for data extraction and
data analysis for pattern discovery. Image analysis is very crucial to analysis of
measured data as it gives details of particular elements of the array. Several techniques
and tools are available for analysis of measued data to gain insight into any pattern
that emerges. The most popular among them are the cluster analysis, temporal expression
profile analysis, and gene regulatory analysis. We will discusss about them in detail.
