BACKGROUND: The aim of this study was to evaluate the association between optic nerve
head (ONH) parameters and branch retinal vein occlusion (BRVO) using spectral domain
optical coherence tomography (SD-OCT). METHODS: Both eyes of 40 patients with unilateral
BRVO (mean age: 67.4 +/- 11.4 years, male: female - 18:22) were enrolled in this study.
Control group consisted of randomly selected single healthy eyes of 40 age and gender
matched volunteers (mean age: 64.7 +/- 15.4 years, male: female - 16:24). ONH parameters
(including optic disc area, optic cup area, neuroretinal rim area, cup volume, rim
volume, cup-disc area ratio, horizontal and vertical cup-disc ratio, average retinal
nerve fiber layer) were measured by SD-OCT. Axial length (AL) of the eyes was measured
by non-contact optical low coherence reflectometry. The ONH parameters of eyes with
BRVO were compared with those of fellow eyes using mixed model, one-way between-groups
analysis of covariance was conducted to compare the ONH parameters of affected and
unaffected fellow eyes in BRVO patients with those of the control eyes keeping confounding
factors, including AL, age and gender under control in the statistical analysis. RESULTS:
None of the investigated ONH parameters of affected BRVO eyes, unaffected fellow eyes
and control eyes were statistically different after controlling for AL, age and gender.
CONCLUSION: Optic disc morphology might not be a potential anatomical predisposing
factor for development of BRVO.