BACKGROUND: Docetaxel is a chemotherapeutic agent of the taxane class of drugs for
the treatment of breast cancer. We present a female patient who noted decreased vision
after docetaxel treatment. CASE PRESENTATION: A 45-year-old female patient received
docetaxel treatment after resection of a breast carcinoma. Funduscopy and optical
coherence tomography (OCT) showed cystoid macular edema on both eyes. Dilated funduscopy
also showed bone spicule-like pigmented deposits, typical for retinitis pigmentosa.
Besides the fundus appearance restricted peripheral vision and scotopic electroretinogram
confirmed the diagnosis of retinitis pigmentosa. Chemotherapy was discontinued following
a consulation with the oncologist of the patient. After five weeks, visual acuity
improved significantly along with decrease of retinal thickness measured by OCT. CONCLUSION:
Docetaxel may cause ocular adverse effects such as cystoid macular edema. Ophthalmological
examination is warranted for patients with visual complaints during docetaxel chemotherapy.