{ "labelLang" : "hun", "responseDate" : "2024-03-29 09:59", "content" : { "otype" : "JournalArticle", "mtid" : 2817878, "status" : "VALIDATED", "published" : true, "unhandledTickets" : 0, "oldTimestamp" : "2018-07-06T12:14:40.000+0000", "deleted" : false, "oldId" : 2817878, "lastRefresh" : "2024-02-17T19:32:33.128+0000", "lastModified" : "2020-03-09T10:21:16.408+0000", "created" : "2015-01-19T19:14:30.000+0000", "creator" : { "otype" : "Author", "mtid" : 10010125, "link" : "/api/author/10010125", "label" : "Ferdinandy Péter (Farmakológia, molekuláris medicina)", "familyName" : "Ferdinandy", "givenName" : "Péter", "published" : true, "oldId" : 10010125, "snippet" : true }, "lastDuplumSearch" : "2024-03-01T00:32:48.802+0000", "adminApproved" : "2015-12-08T18:41:16.000+0000", "adminApprover" : { "otype" : "Admin", "mtid" : 10030236, "link" : "/api/admin/10030236", "label" : "Molnár-Taga Márta (SE_KK_Admin5_TM, admin)", "familyName" : "Molnár-Taga", "givenName" : "Márta", "published" : true, "oldId" : 10030236, "snippet" : true }, "validated" : "2020-03-09T10:21:16.426+0000", "validator" : { "otype" : "Admin", "mtid" : 10060816, "link" : "/api/admin/10060816", "label" : "Berta Wanda (SZTE admin5)", "familyName" : "Berta", "givenName" : "Wanda", "published" : true, "oldId" : 10060816, "snippet" : true }, "core" : true, "citation" : true, "publicationPending" : false, "type" : { "otype" : "PublicationType", "mtid" : 24, "link" : "/api/publicationtype/24", "label" : "Folyóiratcikk", "code" : 24, "otypeName" : "JournalArticle", "listPosition" : 1, "published" : true, "oldId" : 24, "snippet" : true }, "subType" : { "otype" : "SubType", "mtid" : 10000059, "link" : "/api/subtype/10000059", "label" : "Szakcikk (Folyóiratcikk)", "name" : "Szakcikk", "nameEng" : "Article", "docType" : { "otype" : "PublicationType", "mtid" : 24, "link" : "/api/publicationtype/24", "label" : "Folyóiratcikk", "code" : 24, "otypeName" : "JournalArticle", "listPosition" : 1, "published" : true, "oldId" : 24, "snippet" : true }, "listPosition" : 101, "published" : true, "oldId" : 10000059, "snippet" : true }, "category" : { "otype" : "Category", "mtid" : 1, "link" : "/api/category/1", "label" : "Tudományos", "published" : true, "oldId" : 1, "snippet" : true }, "languages" : [ { "otype" : "Language", "mtid" : 10002, "link" : "/api/language/10002", "label" : "Angol", "name" : "Angol", "nameEng" : "English", "published" : true, "oldId" : 2, "snippet" : true } ], "firstAuthor" : "Madonna, R", "authorships" : [ { "otype" : "PersonAuthorship", "mtid" : 5913805, "link" : "/api/authorship/5913805", "label" : "Madonna, R ✉", "listPosition" : 1, "share" : 0.143, "first" : true, "last" : false, "corresponding" : true, "familyName" : "Madonna", "givenName" : "R", "authorTyped" : true, "editorTyped" : false, "otherTyped" : false, "type" : { "otype" : "AuthorshipType", "mtid" : 1, "link" : "/api/authorshiptype/1", "label" : "Szerző", "code" : 0, "published" : true, "oldId" : 0, "snippet" : true }, "published" : false, "oldId" : 21000348, "snippet" : true }, { "otype" : "PersonAuthorship", "mtid" : 5913806, "link" : "/api/authorship/5913806", "label" : "Engel, FB", "listPosition" : 2, "share" : 0.14285715, "first" : false, "last" : false, "familyName" : "Engel", "givenName" : "FB", "authorTyped" : true, "editorTyped" : false, "otherTyped" : false, "type" : { "otype" : "AuthorshipType", "mtid" : 1, "link" : "/api/authorshiptype/1", "label" : "Szerző", "code" : 0, "published" : true, "oldId" : 0, "snippet" : true }, "published" : false, "oldId" : 21000347, "snippet" : true }, { "otype" : "PersonAuthorship", "mtid" : 5913807, "link" : "/api/authorship/5913807", "label" : "Davidson, SM", "listPosition" : 3, "share" : 0.14285715, "first" : false, "last" : false, "familyName" : "Davidson", "givenName" : "SM", "authorTyped" : true, "editorTyped" : false, "otherTyped" : false, "type" : { "otype" : "AuthorshipType", "mtid" : 1, "link" : "/api/authorshiptype/1", "label" : "Szerző", "code" : 0, "published" : true, "oldId" : 0, "snippet" : true }, "published" : false, "oldId" : 21000346, "snippet" : true }, { "otype" : "PersonAuthorship", "mtid" : 5913808, "link" : "/api/authorship/5913808", "label" : "Ferdinandy, P [Ferdinandy, Péter (Farmakológia, mol...), szerző] Farmakológiai és Farmakoterápiás Intézet (SE / AOK / I)", "listPosition" : 4, "share" : 0.14285715, "first" : false, "last" : false, "author" : { "otype" : "Author", "mtid" : 10010125, "link" : "/api/author/10010125", "label" : "Ferdinandy Péter (Farmakológia, molekuláris medicina)", "familyName" : "Ferdinandy", "givenName" : "Péter", "published" : true, "oldId" : 10010125, "snippet" : true }, "familyName" : "Ferdinandy", "givenName" : "P", "authorTyped" : true, "editorTyped" : false, "otherTyped" : false, "type" : { "otype" : "AuthorshipType", "mtid" : 1, "link" : "/api/authorshiptype/1", "label" : "Szerző", "code" : 0, "published" : true, "oldId" : 0, "snippet" : true }, "published" : false, "oldId" : 21000345, "snippet" : true }, { "otype" : "PersonAuthorship", "mtid" : 5913809, "link" : "/api/authorship/5913809", "label" : "Gorbe, A [Görbe, Anikó (orvostudomany), szerző] Biokémiai Intézet (SZTE / SZAOK)", "listPosition" : 5, "share" : 0.14285715, "first" : false, "last" : false, "author" : { "otype" : "Author", "mtid" : 10027602, "link" : "/api/author/10027602", "label" : "Görbe Anikó (orvostudomany)", "familyName" : "Görbe", "givenName" : "Anikó", "published" : true, "oldId" : 10027602, "snippet" : true }, "familyName" : "Gorbe", "givenName" : "A", "authorTyped" : true, "editorTyped" : false, "otherTyped" : false, "type" : { "otype" : "AuthorshipType", "mtid" : 1, "link" : "/api/authorshiptype/1", "label" : "Szerző", "code" : 0, "published" : true, "oldId" : 0, "snippet" : true }, "published" : false, "oldId" : 21000344, "snippet" : true }, { "otype" : "PersonAuthorship", "mtid" : 5913810, "link" : "/api/authorship/5913810", "label" : "Sluijter, JP", "listPosition" : 6, "share" : 0.14285715, "first" : false, "last" : false, "familyName" : "Sluijter", "givenName" : "JP", "authorTyped" : true, "editorTyped" : false, "otherTyped" : false, "type" : { "otype" : "AuthorshipType", "mtid" : 1, "link" : "/api/authorshiptype/1", "label" : "Szerző", "code" : 0, "published" : true, "oldId" : 0, "snippet" : true }, "published" : false, "oldId" : 21000343, "snippet" : true }, { "otype" : "PersonAuthorship", "mtid" : 5913811, "link" : "/api/authorship/5913811", "label" : "Van, Laake LW", "listPosition" : 7, "share" : 0.14285715, "first" : false, "last" : true, "familyName" : "Van", "givenName" : "Laake LW", "authorTyped" : true, "editorTyped" : false, "otherTyped" : false, "type" : { "otype" : "AuthorshipType", "mtid" : 1, "link" : "/api/authorshiptype/1", "label" : "Szerző", "code" : 0, "published" : true, "oldId" : 0, "snippet" : true }, "published" : false, "oldId" : 21000342, "snippet" : true } ], "title" : "Stem cell aging and age-related cardiovascular disease: Perspectives of treatment by ex-vivo stem cell rejuvenation", "identifiers" : [ { "otype" : "PublicationIdentifier", "mtid" : 939077, "link" : "/api/publicationidentifier/939077", "label" : "DOI: 10.2174/1389450116666141205153258", "source" : { "otype" : "PlainSource", "mtid" : 6, "link" : "/api/publicationsource/6", "label" : "DOI", "type" : { "otype" : "PublicationSourceType", "mtid" : 10001, "link" : "/api/publicationsourcetype/10001", "label" : "DOI", "mayHaveOa" : true, "published" : true, "snippet" : true }, "name" : "DOI", "nameEng" : "DOI", "linkPattern" : "https://doi.org/@@@", "publiclyVisible" : true, "published" : true, "oldId" : 6, "snippet" : true }, "oaType" : "PAY", "oaFree" : false, "validState" : "IDENTICAL", "idValue" : "10.2174/1389450116666141205153258", "realUrl" : "https://doi.org/10.2174/1389450116666141205153258", "published" : false, "oldId" : 1265261, "snippet" : true }, { "otype" : "PublicationIdentifier", "mtid" : 939075, "link" : "/api/publicationidentifier/939075", "label" : "WoS: 000359605300002", "source" : { "otype" : "PlainSource", "mtid" : 1, "link" : "/api/publicationsource/1", "label" : "WoS", "type" : { "otype" : "PublicationSourceType", "mtid" : 10003, "link" : "/api/publicationsourcetype/10003", "label" : "Indexelő adatbázis", "mayHaveOa" : false, "published" : true, "snippet" : true }, "name" : "WoS", "nameEng" : "WoS", "linkPattern" : "https://www.webofscience.com/wos/woscc/full-record/@@@", "publiclyVisible" : true, "published" : true, "oldId" : 1, "snippet" : true }, "oaFree" : false, "validState" : "IDENTICAL", "idValue" : "000359605300002", "realUrl" : "https://www.webofscience.com/wos/woscc/full-record/000359605300002", "published" : false, "oldId" : 1222943, "snippet" : true }, { "otype" : "PublicationIdentifier", "mtid" : 939076, "link" : "/api/publicationidentifier/939076", "label" : "Scopus: 84940902140", "source" : { "otype" : "PlainSource", "mtid" : 3, "link" : "/api/publicationsource/3", "label" : "Scopus", "type" : { "otype" : "PublicationSourceType", "mtid" : 10003, "link" : "/api/publicationsourcetype/10003", "label" : "Indexelő adatbázis", "mayHaveOa" : false, "published" : true, "snippet" : true }, "name" : "Scopus", "linkPattern" : "http://www.scopus.com/record/display.url?origin=inward&eid=2-s2.0-@@@", "publiclyVisible" : true, "published" : true, "oldId" : 3, "snippet" : true }, "oaFree" : false, "validState" : "IDENTICAL", "idValue" : "84940902140", "realUrl" : "http://www.scopus.com/record/display.url?origin=inward&eid=2-s2.0-84940902140", "published" : false, "oldId" : 1222941, "snippet" : true }, { "otype" : "PublicationIdentifier", "mtid" : 939078, "link" : "/api/publicationidentifier/939078", "label" : "PubMed: 25479545", "source" : { "otype" : "PlainSource", "mtid" : 17, "link" : "/api/publicationsource/17", "label" : "PubMed", "type" : { "otype" : "PublicationSourceType", "mtid" : 10003, "link" : "/api/publicationsourcetype/10003", "label" : "Indexelő adatbázis", "mayHaveOa" : false, "published" : true, "snippet" : true }, "name" : "PubMed", "nameEng" : "PubMed", "linkPattern" : "http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db=PubMed&list_uids=@@@&dopt=Abstract", "publiclyVisible" : true, "published" : true, "oldId" : 17, "snippet" : true }, "oaFree" : false, "validState" : "IDENTICAL", "idValue" : "25479545", "realUrl" : "http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db=PubMed&list_uids=25479545&dopt=Abstract", "published" : false, "oldId" : 1041691, "snippet" : true }, { "otype" : "PublicationIdentifier", "mtid" : 939079, "link" : "/api/publicationidentifier/939079", "label" : "SZTE Publicatio: 13596", "source" : { "otype" : "SwordSource", "mtid" : 90, "link" : "/api/publicationsource/90", "label" : "SZTE Publicatio", "type" : { "otype" : "PublicationSourceType", "mtid" : 10007, "link" : "/api/publicationsourcetype/10007", "label" : "Repozitórium", "mayHaveOa" : true, "published" : true, "snippet" : true }, "name" : "SZTE Publicatio", "nameEng" : "SZTE Publicatio", "linkPattern" : "http://publicatio.bibl.u-szeged.hu/@@@", "publiclyVisible" : true, "published" : true, "oldId" : 90, "snippet" : true }, "oaType" : "GREEN", "oaFree" : false, "validState" : "IDENTICAL", "idValue" : "13596", "realUrl" : "http://publicatio.bibl.u-szeged.hu/13596", "published" : false, "oldId" : 1798709, "snippet" : true } ], "journal" : { "otype" : "Journal", "mtid" : 10001167, "link" : "/api/journal/10001167", "label" : "CURRENT DRUG TARGETS 1389-4501 1873-5592", "pIssn" : "1389-4501", "eIssn" : "1873-5592", "reviewType" : "REVIEWED", "noIF" : false, "sciIndexed" : true, "scopusIndexed" : true, "lang" : "FOREIGN", "hungarian" : false, "published" : true, "oldId" : 10001167, "snippet" : true }, "volume" : "16", "issue" : "8", "firstPage" : "780", "lastPage" : "785", "firstPageOrInternalIdForSort" : "780", "pageLength" : 6, "publishedYear" : 2015, "abstractText" : "Aging affects endogenous stem cells in terms of functionality and numbers. In particular, during aging the stemness property can decrease because of enhanced apoptotic cell death and senescence. In addition, aging and aging-related co-morbidities affect the paracrine activity of stem cells and the efficiency of their transplantation. Collectively, this leads to a reduction of the capacity of organs to repair themselves, possibly due to a reduced functional capability of stem cells. Therefore, major efforts have been invested to improve the repair capability of stem cells in aged individuals by overexpressing antisenescence and antiapoptotic genes. In this review, we describe critical genes and signaling pathways in stem cell aging and discuss ex vivo genetic modification approaches aimed at stem cell rejuvenation that are of interest for the cardiovascular system.", "subjects" : [ { "otype" : "Classification", "mtid" : 12125, "link" : "/api/classification/12125", "label" : "Általános orvostudomány", "published" : true, "snippet" : true }, { "otype" : "Classification", "mtid" : 10545, "link" : "/api/classification/10545", "label" : "Biológiai tudományok", "published" : true, "snippet" : true }, { "otype" : "Classification", "mtid" : 12215, "link" : "/api/classification/12215", "label" : "Klinikai orvostan", "published" : true, "snippet" : true } ], "digital" : null, "printed" : null, "sourceYear" : 2015, "packet" : "(Ferdinandy Péter (Biokémiai farmakológia); 2015.01.19. 20:13:38)", "foreignEdition" : true, "foreignLanguage" : true, "fullPublication" : true, "conferencePublication" : false, "nationalOrigin" : true, "missingAuthor" : false, "oaType" : "GREEN", "oaTypeDisp" : "GREEN", "oaCheckDate" : "2024-02-17", "oaFree" : true, "oaLink" : "http://publicatio.bibl.u-szeged.hu/13596", "oaByAuthor" : { "otype" : "Admin", "mtid" : 10058176, "link" : "/api/admin/10058176", "label" : "Nagyné Tari Emese (SZTE admin5)", "familyName" : "Nagyné Tari", "givenName" : "Emese", "published" : true, "oldId" : 10058176, "snippet" : true }, "citationCount" : 8, "citationCountUnpublished" : 0, "citationCountWoOther" : 8, "independentCitCountWoOther" : 3, "nationalOriginCitationCount" : 4, "foreignEditionCitationCount" : 8, "doiCitationCount" : 8, "wosCitationCount" : 7, "scopusCitationCount" : 7, "wosScopusCitationCount" : 7, "wosScopusCitationCountWoOther" : 7, "wosScopusIndependentCitationCount" : 2, "wosScopusIndependentCitationCountWoOther" : 2, "independentCitationCount" : 3, "selfCitationCount" : 5, "unhandledCitationCount" : 0, "citingPubCount" : 8, "independentCitingPubCount" : 3, "citingPubCountWoOther" : 8, "independentCitingPubCountWoOther" : 3, "unhandledCitingPubCount" : 0, "citedPubCount" : 9, "citedCount" : 9, "pubStats" : { "types" : [ { "type" : "Folyóiratcikk", "typeEng" : "Journal Article", "code" : 24, "count" : 8 }, { "type" : "Könyvrészlet", "typeEng" : "Chapter in Book", "code" : 25, "count" : 0 }, { "type" : "Könyv", "typeEng" : "Book", "code" : 23, "count" : 0 }, { "type" : "Egyéb konferenciaközlemény", "typeEng" : "Conference paper", "code" : 31, "count" : 0 }, { "type" : "Egyéb konferenciakötet", "typeEng" : "Conference proceedings", "code" : 32, "count" : 0 }, { "type" : "Oltalmi formák", "typeEng" : "Protection forms", "code" : 26, "count" : 0 }, { "type" : "Disszertáció", "typeEng" : "Thesis", "code" : 28, "count" : 0 }, { "type" : "Egyéb", "typeEng" : "Miscellaneous", "code" : 29, "count" : 0 }, { "type" : "Alkotás", "typeEng" : "Achievement", "code" : 22, "count" : 0 }, { "type" : "Kutatási adat", "typeEng" : "Research data", "code" : 33, "count" : 0 } ], "citationTypes" : [ { "type" : "Folyóiratcikk", "typeEng" : "Journal Article", "code" : 24, "countUnknown" : 0, "countIndependent" : 0, "countSelfCitation" : 0 }, { "type" : "Könyvrészlet", "typeEng" : "Chapter in Book", "code" : 25, "countUnknown" : 0, "countIndependent" : 0, "countSelfCitation" : 0 }, { "type" : "Könyv", "typeEng" : "Book", "code" : 23, "countUnknown" : 0, "countIndependent" : 0, "countSelfCitation" : 0 }, { "type" : "Egyéb konferenciaközlemény", "typeEng" : "Conference paper", "code" : 31, "countUnknown" : 0, "countIndependent" : 0, "countSelfCitation" : 0 }, { "type" : "Egyéb konferenciakötet", "typeEng" : "Conference proceedings", "code" : 32, "countUnknown" : 0, "countIndependent" : 0, "countSelfCitation" : 0 }, { "type" : "Oltalmi formák", "typeEng" : "Protection forms", "code" : 26, "countUnknown" : 0, "countIndependent" : 0, "countSelfCitation" : 0 }, { "type" : "Disszertáció", "typeEng" : "Thesis", "code" : 28, "countUnknown" : 0, "countIndependent" : 0, "countSelfCitation" : 0 }, { "type" : "Egyéb", "typeEng" : "Miscellaneous", "code" : 29, "countUnknown" : 0, "countIndependent" : 0, "countSelfCitation" : 0 }, { "type" : "Alkotás", "typeEng" : "Achievement", "code" : 22, "countUnknown" : 0, "countIndependent" : 0, "countSelfCitation" : 0 }, { "type" : "Kutatási adat", "typeEng" : "Research data", "code" : 33, "countUnknown" : 0, "countIndependent" : 0, "countSelfCitation" : 0 } ], "years" : [ { "year" : 2015, "publicationCount" : 0, "citationCount" : 1, "independentCitationCount" : 1, "citingPubCount" : 1, "independentCitingPubCount" : 1, "oaStats" : null, "oaStats2" : null }, { "year" : 2016, "publicationCount" : 0, "citationCount" : 3, "independentCitationCount" : 0, "citingPubCount" : 3, "independentCitingPubCount" : 0, "oaStats" : null, "oaStats2" : null }, { "year" : 2017, "publicationCount" : 0, "citationCount" : 0, "independentCitationCount" : 0, "citingPubCount" : 0, "independentCitingPubCount" : 0, "oaStats" : null, "oaStats2" : null }, { "year" : 2018, "publicationCount" : 0, "citationCount" : 2, "independentCitationCount" : 2, "citingPubCount" : 2, "independentCitingPubCount" : 2, "oaStats" : null, "oaStats2" : null }, { "year" : 2019, "publicationCount" : 0, "citationCount" : 1, "independentCitationCount" : 0, "citingPubCount" : 1, "independentCitingPubCount" : 0, "oaStats" : null, "oaStats2" : null }, { "year" : 2020, "publicationCount" : 0, "citationCount" : 1, "independentCitationCount" : 0, "citingPubCount" : 1, "independentCitingPubCount" : 0, "oaStats" : null, "oaStats2" : null } ] }, "ratings" : [ { "otype" : "SjrRating", "mtid" : 11012300, "link" : "/api/sjrrating/11012300", "label" : "sjr:Q1 (2015) Scopus - Clinical Biochemistry CURRENT DRUG TARGETS 1389-4501", "listPos" : 31, "rankValue" : 0.24, "type" : "journal", "ratingType" : { "otype" : "RatingType", "mtid" : 10002, "link" : "/api/ratingtype/10002", "label" : "sjr", "code" : "sjr", "published" : true, "snippet" : true }, "subject" : { "otype" : "ClassificationExternal", "mtid" : 1308, "link" : "/api/classificationexternal/1308", "label" : "Scopus - Clinical Biochemistry", "published" : true, "oldId" : 1308, "snippet" : true }, "ranking" : "Q1", "calculation" : "DIRECT", "published" : true, "snippet" : true } ], "ratingsForSort" : "Q1", "hasCitationDuplums" : false, "userChangeableUntil" : "2015-12-08T18:41:16.000+0000", "publishDate" : "2015-01-19T19:16:34.000+0000", "directInstitutesForSort" : "Biokémiai Intézet (SZTE / SZAOK); Farmakológiai és Farmakoterápiás Intézet (SE / AOK / I)", "ownerAuthorCount" : 2, "ownerInstituteCount" : 13, "directInstituteCount" : 2, "authorCount" : 7, "contributorCount" : 0, "hasQualityFactor" : true, "link" : "/api/publication/2817878", "label" : "Madonna R et al. Stem cell aging and age-related cardiovascular disease: Perspectives of treatment by ex-vivo stem cell rejuvenation. (2015) CURRENT DRUG TARGETS 1389-4501 1873-5592 16 8 780-785", "template" : "