MOTIVATION: Extracellular vesicles (EVs) are spherical bilayered proteolipids, harboring
various bioactive molecules. Due to the complexity of the vesicular nomenclatures
and components, online searches for EV-related publications and vesicular components
are currently challenging. RESULTS: We present an improved version of EVpedia, a public
database for EVs research. This community web portal contains a database of publications
and vesicular components, identification of orthologous vesicular components, bioinformatic
tools and a personalized function. EVpedia includes 6879 publications, 172 080 vesicular
components from 263 high-throughput datasets, and has been accessed more than 65 000
times from more than 750 cities. In addition, about 350 members from 73 international
research groups have participated in developing EVpedia. This free web-based database
might serve as a useful resource to stimulate the emerging field of EV research. Availability
and implementation: The web site was implemented in PHP, Java, MySQL and Apache, and
is freely available at http://evpedia.info. CONTACT: ysgho@postech.ac.kr.