https://m2.mtmt.hu/ hun 2026-05-01 07:02 JournalArticle 2786960 VALIDATED true 0 2018-10-02T08:54:25.000+0000 false 2786960 2026-04-16T14:46:04.699+0000 2026-04-15T15:37:07.722+0000 2014-12-04T08:53:24.000+0000 true 10000800 Bereczki Dániel /api/author/10000800 Author true 10000800 2026-03-20T14:53:49.807+0000 2026-03-20T14:53:49.807+0000 2021-06-14T15:52:14.022+0000 true 10036488 Szabó Szilárd /api/admin/10036488 Admin true 10036488 2026-04-15T15:37:08.009+0000 true 10003134 Wolf György /api/admin/10003134 Admin true 10003134 Admin 10003134 /api/admin/10003134 Wolf György true 10003134 true 2026-04-15T06:49:54.708+0000 true false true 24 24 /api/publicationtype/24 PublicationType 1 true 24 JournalArticle true 10000059 Article true 24 24 /api/publicationtype/24 PublicationType 1 true 24 JournalArticle /api/subtype/10000059 Szakcikk SubType 101 true 10000059 true 1 /api/category/1 Category true 1 Fekete, K Predictors of Long-term Outcome after Intravenous or Intra-arterial Recombinant Tissue Plasminogen Activator Treatment in the Eastern Hungarian Thrombolysis Database. true true /api/journal/10006074 REVIEWED true false 10006074 false 10006074 true 1052-3057 1532-8511 Journal FOREIGN 24 1 117 124 117 8 2015 BACKGROUND: This prospective single-center study aimed to identify features determining long-term outcome after thrombolysis in a Central European stroke population. METHODS: Between 1 January, 2004, and 31 December, 2010, 415 patients were treated with recombinant tissue plasminogen activator at the Department of Neurology, University of Debrecen. Stroke severity by the National Institute of Health Stroke Scale score (NIHSSS) and imaging findings by the Alberta Stroke Programme Early Computed Tomography score (ASPECTS) were evaluated on admission and 1 day later. The modified Rankin Scale (mRS) at 3 months and case fatality at 1 year were evaluated. Independent predictors of outcome were identified by multivariate testing. RESULTS: Data of 369 patients were analyzed. Median NIHSSS was 12 (interquartile range [IQR], 8-17) on admission and 10 (IQR, 5-16) at 24 hours. Arterial occlusion was found in 55%. Symptomatic intracerebral hemorrhage (SICH) was detected in 3.8%. Outcome was significantly worse, and SICH was more frequent in intra-arterially treated patients. At 3 months, one third of the patients were independent (mRS </=2), and 23% were dead. At 1 year 2 of 3 patients were alive. Significant independent predictors of disability at 3 months were 24-hour NIHSSS, admission ASPECTS, admission glucose level, and treatment modality. Only the 24-hour NIHSSS was a significant predictor of case fatality at 1 year. CONCLUSIONS: Although short-term outcome was similar, the 3-month and 1-year outcomes were worse than data from previous reports. A more efficient health care program should be implemented after stroke to maintain the favorable effect of thrombolysis in the long term. 2014 74588 true true true false true false CLOSED 2026-04-16 false true 10052382 INAKTÍV_Őszi Alexandra /api/admin/10052382 Admin true 10052382 7 0 5 0 6 4 5 4 5 5 5 0 0 1 6 0 7 1 5 0 0 2 2 Folyóiratcikk Journal Article 24 5 Könyvrészlet Chapter in Book 25 0 Könyv Book 23 0 Egyéb konferenciaközlemény Conference paper 31 0 Egyéb konferenciakötet Conference proceedings 32 0 Oltalmi formák Protection forms 26 0 Disszertáció Thesis 28 2 Egyéb Miscellaneous 29 0 Alkotás Achievement 22 0 Kutatási adat Research data 33 0 Folyóiratcikk Journal Article 24 0 0 0 Könyvrészlet Chapter in Book 25 0 0 0 Könyv Book 23 0 0 0 Egyéb konferenciaközlemény Conference paper 31 0 0 0 Egyéb konferenciakötet Conference proceedings 32 0 0 0 Oltalmi formák Protection forms 26 0 0 0 Disszertáció Thesis 28 0 0 0 Egyéb Miscellaneous 29 0 0 0 Alkotás Achievement 22 0 0 0 Kutatási 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2742 /api/classificationexternal/2742 true 2742 true Q1 DIRECT true true /api/publication/2786960 <div class="JournalArticle Publication long-list"> <div class="authors"> <img title="Forrásközlemény" style="float: left" src="/frontend/resources/grid/publication-core-icon.png"> <img title="Idézőközlemény" style="float: left" src="/frontend/resources/grid/publication-citation-icon.png"> <div class="autype autype0"> <span class="author-name" mtid="10038837"><a href="/gui2/?type=authors&mode=browse&sel=10038837" target="_blank">Fekete K (<span class="authorship-author-name">Fekete Klára</span> <span class="authorAux-mtmt"> neurológia, klinikai neurofiziologia</span>) </a> </span> <span class="author-affil"><span title="Debreceni Egyetem">DE</span>/<span title="Általános Orvostudományi Kar">ÁOK</span>/Neurológiai Tanszék</span> ;&nbsp;&nbsp;&nbsp; <span class="author-name" mtid="10039291"><a href="/gui2/?type=authors&mode=browse&sel=10039291" target="_blank">Marton S (<span class="authorship-author-name">Márton Sándor József</span> <span class="authorAux-mtmt"> alkalmazott statisztika, társadalomtudományok m...</span>) </a> </span> <span class="author-affil"><span title="Debreceni Egyetem">DE</span>/<span title="Bölcsészettudományi Kar">BTK</span>/Politikatudományi és Szociológiai Intézet</span> ;&nbsp;&nbsp;&nbsp; <span class="author-name" >Toth J </span> ;&nbsp;&nbsp;&nbsp; <span class="author-name" mtid="10000492"><a href="/gui2/?type=authors&mode=browse&sel=10000492" target="_blank">Csiba L (<span class="authorship-author-name">Csiba László</span> <span class="authorAux-mtmt"> Neurológia</span>) </a> </span> <span class="author-affil"><span title="Debreceni Egyetem">DE</span>/<span title="Általános Orvostudományi Kar">ÁOK</span>/Neurológiai Tanszék</span> ;&nbsp;&nbsp;&nbsp; <span class="author-name" mtid="10002463"><a href="/gui2/?type=authors&mode=browse&sel=10002463" target="_blank">Fekete I (<span class="authorship-author-name">Fekete István</span> <span class="authorAux-mtmt"> Idegbetegségek, neurológia</span>) </a> </span> <span class="author-affil"><span title="Debreceni Egyetem">DE</span>/<span title="Általános Orvostudományi Kar">ÁOK</span>/Neurológiai Tanszék</span> ;&nbsp;&nbsp;&nbsp; <span class="author-name" mtid="10000800"><a href="/gui2/?type=authors&mode=browse&sel=10000800" target="_blank">Bereczki D ✉ (<span class="authorship-author-name">Bereczki Dániel</span> <span class="authorAux-mtmt"> Stroke</span>) </a> </span> <span class="author-affil"><span title="Semmelweis Egyetem">SE</span>/<span title="Általános Orvostudományi Kar">AOK</span>/<span title="Klinikum">K</span>/Neurológiai Klinika</span> </div> </div> <div class="title"><a href="/gui2/?mode=browse&params=publication;2786960" target="_blank">Predictors of Long-term Outcome after Intravenous or Intra-arterial Recombinant Tissue Plasminogen Activator Treatment in the Eastern Hungarian Thrombolysis Database.</a></div> <div> <span class="journal-title">JOURNAL OF STROKE AND CEREBROVASCULAR DISEASES</span> <span class="journal-issn">(<a target="_blank" href="https://portal.issn.org/resource/ISSN/1052-3057">1052-3057</a> <a target="_blank" href="https://portal.issn.org/resource/ISSN/1532-8511">1532-8511</a>)</span>: <span class="journal-volume">24</span> <span class="journal-issue">1</span> <span class="page"> pp 117-124 </span> <span class="year">(2015)</span> </div> <div class="pub-footer"> <span class="language" xmlns="http://www.w3.org/1999/html">Nyelv: Angol | </span> <span class="identifiers"> <span class="id identifier oa_PAY" title=" Fizetős "> <a style="color:blue" title="10.1016/j.jstrokecerebrovasdis.2014.07.054" target="_blank" href="https://doi.org/10.1016/j.jstrokecerebrovasdis.2014.07.054"> DOI </a> </span> <span class="id identifier oa_CLOSED" title=" Zárt "> <a style="color:blue" title="222319" target="_blank" href="http://hdl.handle.net/2437/222319"> DEA </a> </span> <span class="id identifier 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href="http://linkinghub.elsevier.com/retrieve/pii/S1052305714004030"> Egyéb URL </a> </span> </span> <OnlyViewableByAuthor><div class="ratings"> <div class="journal-subject">Folyóirat szakterülete: Scopus - Rehabilitation&nbsp;&nbsp;&nbsp;SJR indikátor:&nbsp;Q1</div> <div class="journal-subject">Folyóirat szakterülete: Scopus - Cardiology and Cardiovascular Medicine&nbsp;&nbsp;&nbsp;SJR indikátor:&nbsp;Q2</div> <div class="journal-subject">Folyóirat szakterülete: Scopus - Neurology (clinical)&nbsp;&nbsp;&nbsp;SJR indikátor:&nbsp;Q2</div> <div class="journal-subject">Folyóirat szakterülete: Scopus - Surgery&nbsp;&nbsp;&nbsp;SJR indikátor:&nbsp;Q2</div> </div></OnlyViewableByAuthor> <div class="publication-citation" style="margin-left: 0.5cm;"> <span title="Nyilvános idézőközlemények összesen, említések nélkül" class="citingPub-count">Nyilvános idéző összesen: 7</span> | Független: 1 | Függő: 6 | Nem jelölt: 0 | WoS jelölt: 4 | Scopus jelölt:&nbsp;5 | WoS/Scopus jelölt:&nbsp;5 | DOI 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