{ "labelLang" : "hun", "responseDate" : "2024-03-28 13:58", "content" : { "otype" : "JournalArticle", "mtid" : 27617488, "status" : "ADMIN_APPROVED", "published" : true, "comment" : "Cited By :45 \n Export Date: 5 December 2023 \n CODEN: JMNEE \n Correspondence Address: Abad, C.; INSERM U1234 PANTHER, 22 Boulevard Gambetta, France; email: catalina.abad-rabat@univ-rouen.fr", "unhandledTickets" : 0, "oldTimestamp" : "2018-09-03T11:06:03.000+0000", "deleted" : false, "oldId" : 17617488, "lastRefresh" : "2023-12-05T12:32:47.571+0000", "lastModified" : "2023-11-21T21:29:34.739+0000", "created" : "2018-08-27T08:06:48.000+0000", "creator" : { "otype" : "Author", "mtid" : 10000698, "link" : "/api/author/10000698", "label" : "Ferencz Andrea (Sebészet)", "familyName" : "Ferencz", "givenName" : "Andrea", "published" : true, "oldId" : 10000698, "snippet" : true }, "lastDuplumSearch" : "2023-12-05T12:27:27.695+0000", "adminApproved" : "2023-11-21T21:29:35.178+0000", "adminApprover" : { "otype" : "Admin", "mtid" : 10065569, "link" : "/api/admin/10065569", "label" : "Pécsi Éva (MTMT Közp 3, admin)", "familyName" : "Pécsi", "givenName" : "Éva", "published" : true, "snippet" : true }, "core" : false, "citation" : true, "publicationPending" : false, "type" : { "otype" : "PublicationType", "mtid" : 24, "link" : "/api/publicationtype/24", "label" : "Folyóiratcikk", "code" : 24, "otypeName" : "JournalArticle", "listPosition" : 1, "published" : true, "oldId" : 24, "snippet" : true }, "subType" : { "otype" : "SubType", "mtid" : 10000059, "link" : "/api/subtype/10000059", "label" : "Szakcikk (Folyóiratcikk)", "name" : "Szakcikk", "nameEng" : "Article", "docType" : { "otype" : "PublicationType", "mtid" : 24, "link" : "/api/publicationtype/24", "label" : "Folyóiratcikk", "code" : 24, "otypeName" : "JournalArticle", "listPosition" : 1, "published" : true, "oldId" : 24, "snippet" : true }, "listPosition" : 101, "published" : true, "oldId" : 10000059, "snippet" : true }, "category" : { "otype" : "Category", "mtid" : 1, "link" : "/api/category/1", "label" : "Tudományos", "published" : true, "oldId" : 1, "snippet" : true }, "languages" : [ { "otype" : "Language", "mtid" : 10002, "link" : "/api/language/10002", "label" : "Angol", "name" : "Angol", "nameEng" : "English", "published" : true, "oldId" : 2, "snippet" : true } ], "firstAuthor" : "Abad, Catalina", "authorships" : [ { "otype" : "PersonAuthorship", "mtid" : 83411208, "link" : "/api/authorship/83411208", "label" : "Abad, Catalina", "listPosition" : 1, "share" : 0.0, "first" : true, "last" : false, "familyName" : "Abad", "givenName" : "Catalina", "authorTyped" : true, "editorTyped" : false, "otherTyped" : false, "type" : { "otype" : "AuthorshipType", "mtid" : 1, "link" : "/api/authorshiptype/1", "label" : "Szerző", "code" : 0, "published" : true, "oldId" : 0, "snippet" : true }, "published" : false, "oldId" : 175407556, "snippet" : true }, { "otype" : "PersonAuthorship", "mtid" : 83411209, "link" : "/api/authorship/83411209", "label" : "Tan, Yossan-Var", "listPosition" : 2, "share" : 0.0, "first" : false, "last" : true, "familyName" : "Tan", "givenName" : "Yossan-Var", "authorTyped" : true, "editorTyped" : false, "otherTyped" : false, "type" : { "otype" : "AuthorshipType", "mtid" : 1, "link" : "/api/authorshiptype/1", "label" : "Szerző", "code" : 0, "published" : true, "oldId" : 0, "snippet" : true }, "published" : false, "oldId" : 175407555, "snippet" : true } ], "title" : "Immunomodulatory Roles of PACAP and VIP: Lessons from Knockout Mice", "subTitle" : "Lessons from Knockout Mice.", "identifiers" : [ { "otype" : "PublicationIdentifier", "mtid" : 14430907, "link" : "/api/publicationidentifier/14430907", "label" : "DOI: 10.1007/s12031-018-1150-y", "source" : { "otype" : "PlainSource", "mtid" : 6, "link" : "/api/publicationsource/6", "label" : "DOI", "type" : { "otype" : "PublicationSourceType", "mtid" : 10001, "link" : "/api/publicationsourcetype/10001", "label" : "DOI", "mayHaveOa" : true, "published" : true, "snippet" : true }, "name" : "DOI", "nameEng" : "DOI", "linkPattern" : "https://doi.org/@@@", "publiclyVisible" : true, "published" : true, "oldId" : 6, "snippet" : true }, "validState" : "IDENTICAL", "idValue" : "10.1007/s12031-018-1150-y", "realUrl" : "https://doi.org/10.1007/s12031-018-1150-y", "published" : false, "oldId" : 18000454, "snippet" : true }, { "otype" : "PublicationIdentifier", "mtid" : 15128237, "link" : "/api/publicationidentifier/15128237", "label" : "WoS: 000445191700012", "source" : { "otype" : "PlainSource", "mtid" : 1, "link" : "/api/publicationsource/1", "label" : "WoS", "type" : { "otype" : "PublicationSourceType", "mtid" : 10003, "link" : "/api/publicationsourcetype/10003", "label" : "Indexelő adatbázis", "mayHaveOa" : false, "published" : true, "snippet" : true }, "name" : "WoS", "nameEng" : "WoS", "linkPattern" : "https://www.webofscience.com/wos/woscc/full-record/@@@", "publiclyVisible" : true, "published" : true, "oldId" : 1, "snippet" : true }, "validState" : "IDENTICAL", "idValue" : "000445191700012", "realUrl" : "https://www.webofscience.com/wos/woscc/full-record/000445191700012", "published" : true, "snippet" : true }, { "otype" : "PublicationIdentifier", "mtid" : 15082315, "link" : "/api/publicationidentifier/15082315", "label" : "Scopus: 85051415019", "source" : { "otype" : "PlainSource", "mtid" : 3, "link" : "/api/publicationsource/3", "label" : "Scopus", "type" : { "otype" : "PublicationSourceType", "mtid" : 10003, "link" : "/api/publicationsourcetype/10003", "label" : "Indexelő adatbázis", "mayHaveOa" : false, "published" : true, "snippet" : true }, "name" : "Scopus", "linkPattern" : "http://www.scopus.com/record/display.url?origin=inward&eid=2-s2.0-@@@", "publiclyVisible" : true, "published" : true, "oldId" : 3, "snippet" : true }, "validState" : "IDENTICAL", "idValue" : "85051415019", "realUrl" : "http://www.scopus.com/record/display.url?origin=inward&eid=2-s2.0-85051415019", "published" : false, "snippet" : true }, { "otype" : "PublicationIdentifier", "mtid" : 14644435, "link" : "/api/publicationidentifier/14644435", "label" : "PubMed: 30105629", "source" : { "otype" : "PlainSource", "mtid" : 17, "link" : "/api/publicationsource/17", "label" : "PubMed", "type" : { "otype" : "PublicationSourceType", "mtid" : 10003, "link" : "/api/publicationsourcetype/10003", "label" : "Indexelő adatbázis", "mayHaveOa" : false, "published" : true, "snippet" : true }, "name" : "PubMed", "nameEng" : "PubMed", "linkPattern" : "http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db=PubMed&list_uids=@@@&dopt=Abstract", "publiclyVisible" : true, "published" : true, "oldId" : 17, "snippet" : true }, "validState" : "IDENTICAL", "idValue" : "30105629", "realUrl" : "http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db=PubMed&list_uids=30105629&dopt=Abstract", "published" : false, "snippet" : true } ], "journal" : { "otype" : "Journal", "mtid" : 2675, "link" : "/api/journal/2675", "label" : "JOURNAL OF MOLECULAR NEUROSCIENCE 0895-8696 1559-1166", "pIssn" : "0895-8696", "eIssn" : "1559-1166", "reviewType" : "REVIEWED", "noIF" : false, "sciIndexed" : true, "scopusIndexed" : true, "lang" : "FOREIGN", "hungarian" : false, "published" : true, "oldId" : 2675, "snippet" : true }, "volume" : "66", "issue" : "1", "firstPage" : "102", "lastPage" : "113", "firstPageOrInternalIdForSort" : "102", "pageLength" : 12, "publishedYear" : 2018, "abstractText" : "A bidirectional cross-talk is established between the nervous and immune systems through common mediators including neuropeptides, neurotransmitters, and cytokines. Among these, PACAP and VIP are two highly related neuropeptides widely distributed in the organism with purported immunomodulatory actions. Due to their well-known anti-inflammatory properties, administration of these peptides has proven to be beneficial in models of acute and chronic inflammatory diseases. Nevertheless, the relevance of the endogenous source of these peptides in the modulation of immune responses remains to be elucidated. The development of transgenic mice with specific deletions in the genes coding for these neuropeptides (Vip and Adcyap1) or for their G-protein-coupled receptors VPAC1, VPAC2, and PAC1 (Vipr1, Vipr2, Adcyap1r1) has allowed to address this question, underscoring the complexity of the immunoregulatory properties of PACAP and VIP. The goal of this review is to integrate the existing information on the immune phenotypes of mice deficient for PACAP, VIP, or their receptors, to provide a global view on the roles of these endogenous neuropeptides during immunological health and disease.", "keywords" : [ { "otype" : "Keyword", "mtid" : 64, "link" : "/api/keyword/64", "label" : "Inflammation", "published" : true, "oldId" : 64, "snippet" : true }, { "otype" : "Keyword", "mtid" : 739, "link" : "/api/keyword/739", "label" : "VIP", "published" : true, "oldId" : 739, "snippet" : true }, { "otype" : "Keyword", "mtid" : 1206, "link" : "/api/keyword/1206", "label" : "neuropeptides", "published" : true, "oldId" : 1206, "snippet" : true }, { "otype" : "Keyword", "mtid" : 2013, "link" : "/api/keyword/2013", "label" : "PACAP", "published" : true, "oldId" : 2013, "snippet" : true }, { "otype" : "Keyword", "mtid" : 1027389, "link" : "/api/keyword/1027389", "label" : "Knockout", "published" : true, "oldId" : 1027389, "snippet" : true }, { "otype" : "Keyword", "mtid" : 1069492, "link" : "/api/keyword/1069492", "label" : "neuroimmunology", "published" : true, "oldId" : 1069492, "snippet" : true } ], "digital" : null, "printed" : null, "sourceYear" : 2018, "packet" : "616771", "foreignEdition" : true, "foreignLanguage" : true, "fullPublication" : true, "conferencePublication" : false, "nationalOrigin" : false, "missingAuthor" : false, "oaType" : "NONE", "oaCheckDate" : "2023-12-05", "oaFree" : false, "citationCount" : 0, "citationCountUnpublished" : 0, "citationCountWoOther" : 0, "independentCitCountWoOther" : 0, "doiCitationCount" : 0, "wosCitationCount" : 0, "scopusCitationCount" : 0, "independentCitationCount" : 0, "unhandledCitationCount" : 0, "citingPubCount" : 0, "independentCitingPubCount" : 0, "unhandledCitingPubCount" : 0, "citedPubCount" : 8, "citedCount" : 8, "ratings" : [ { "otype" : "SjrRating", "mtid" : 10992189, "link" : "/api/sjrrating/10992189", "label" : "sjr:Q1 (2018) Scopus - Medicine (miscellaneous) JOURNAL OF MOLECULAR NEUROSCIENCE 0895-8696 1559-1166", "listPos" : 631, "rankValue" : 0.24, "type" : "journal", "ratingType" : { "otype" : "RatingType", "mtid" : 10002, "link" : "/api/ratingtype/10002", "label" : "sjr", "code" : "sjr", "published" : true, "snippet" : true }, "subject" : { "otype" : "ClassificationExternal", "mtid" : 2701, "link" : "/api/classificationexternal/2701", "label" : "Scopus - Medicine (miscellaneous)", "published" : true, "oldId" : 2701, "snippet" : true }, "ranking" : "Q1", "calculation" : "DIRECT", "published" : true, "snippet" : true } ], "ratingsForSort" : "Q1", "hasCitationDuplums" : false, "userChangeableUntil" : "2018-12-06T09:18:41.054+0000", "publishDate" : "2018-09-03T11:06:03.000+0000", "directInstitutesForSort" : "", "ownerAuthorCount" : 46, "ownerInstituteCount" : 128, "directInstituteCount" : 0, "authorCount" : 2, "contributorCount" : 0, "hasQualityFactor" : true, "link" : "/api/publication/27617488", "label" : "Abad Catalina et al. Immunomodulatory Roles of PACAP and VIP: Lessons from Knockout Mice: Lessons from Knockout Mice.. (2018) JOURNAL OF MOLECULAR NEUROSCIENCE 0895-8696 1559-1166 66 1 102-113", "template" : "