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Rev. Genet, 11, pp. 367-379 ;\n Elowitz, M.B., Leibler, S., A synthetic oscillatory network of transcriptional regulators (2000) Nature, 403, pp. 335-338 ;\n Gardner, T.S., Cantor, C.R., Collins, J.J., Construction of a genetic toggle switch in Escherichia coli (2000) Nature, 403, pp. 339-342 ;\n Milias-Argeitis, A., Summers, S., Stewart-Ornstein, J., Zuleta, I., Pincus, D., El-Samad, H., Khammash, M., Lygeros, J., In silico feedback for in vivo regulation of a gene expression circuit (2011) Nat. Biotechnol, 29, pp. 1114-1116 ;\n Menolascina, F., Fiore, G., Orabona, E., De Stefano, L., Ferry, M., Hasty, J., Di Bernardo, M., Di Bernardo, D., In-vivo real-time control of protein expression from endogenous and synthetic gene networks (2014) Plos Comput. Biol, 10 ;\n McMahon, S.S., Lenive, O., Filippi, S., Stumpf, M.P.H., Information processing by simple molecular motifs and susceptibility to noise (2015) J. R. Soc. Interface, 12 ;\n Filippi, S., Robustness of MEK-ERK dynamics and origins of cell-to-cell variability in MAPK signaling (2016) Cell Rep, 15, pp. 2524-2535 ;\n Fu, A.Q., Pachter, L., Estimating intrinsic and extrinsic noise from single-cell gene expression measurements (2016) Stat. Appl. Genet. Mol. Biol, 15, pp. 447-471 ;\n Girard, A., Reachability of uncertain linear systems using zonotopes (2005) Hybrid Systems: Computation and Control, pp. 291-305. , (eds M Morari, L Thiele, Berlin, Germany: Springer ;\n Audemard, G., Bozzano, M., Cimatti, A., Sebastiani, R., Verifying industrial hybrid systems with MathSAT (2005) Electron. Notes Theor. Comput. Sci, 119, pp. 17-32 ;\n Cross, E.A., Mitchell, I.M., Level set methods for computing reachable sets of systems with differential algebraic equation dynamics (2008) In American Control Conf, pp. 2260-2265. , Seattle, WA, 11–13 June ;\n Prandini, M., Hu, J., Application of reachability analysis for stochastic hybrid systems to aircraft conflict prediction (2009) IEEE Trans. Automat. Control, 54, pp. 913-917 ;\n Scacchioli, A., Bayen, A.M., Stojadinovic, B., Assessment of uncertainty propagation in the dynamic response of single-degree-of-freedom structures using reachability analysis (2014) J. Eng. Mech, 140, pp. 1-12 ;\n Althoff, M., Leguernic, C., Krogh, B.H., Reachable set computation for uncertain time-varying linear systems (2011) Proc. of the 14Th Int. Conf. on Hybrid Systems: Computation and Control, HSCC ’11, pp. 93-102. , New York, NY: ACM ;\n Kurzhanski, A.B., Vályi, I., (1997) Ellipsoidal Calculus for Estimation and Control, , Laxenburg, Austria: IIASA ;\n Greenstreet, M.R., Mitchell, I., (1999) Reachability Analysis Using Polygonal Projections, 1569, pp. 103-116. , Berlin, Heidelberg: Springer ;\n Han, Z., Krogh, B.H., Reachability analysis of large-scale affine systems using low-dimensional polytopes (2006) Hybrid Systems: Computation and Control, pp. 287-301. , (eds J Hespanha, A Tiwari, Berlin, Heidelberg: Springer ;\n Asarin, E., Dang, T., Girard, A., Reachability analysis of nonlinear systems using conservative approximation (2003) Hybrid Systems: Computation and Control (Eds O Maler, a Pnueli). LNCS, 2623, pp. 20-35. , Berlin, Heidelberg: Springer ;\n Mitchell, I.M., Templeton, J.A., A toolbox of Hamilton-Jacobi solvers for analysis of nondeterministic continuous and hybrid systems (2005) Hybrid Systems: Computation and Control, pp. 480-494. , (eds M Morari, L Thiele, Berlin, Heidelberg: Springer ;\n Althoff, M., Krogh, B.H., Reachability analysis of nonlinear differential-algebraic systems (2014) IEEE Trans. Automat. Control, 59, pp. 371-383 ;\n Szederkényi, G., Kovács, M., Hangos, K.M., Reachability of nonlinear fed-batch fermentation processes (2002) Int. J. Robust Nonlin. Control, 12, pp. 1109-1124 ;\n Brim, L., Fabriková, J., Drazan, S., Safránek, D., Reachability in biochemical dynamical systems by quantitative discrete approximation (2011) Comput. Res. Repository, , http://arxiv.org/abs/1107.5924 ;\n Halász, Á.M., Kumar, V., Imieliński, M., Belta, C., Sokolsky, O., Pathak, S., Rubin, H., Analysis of lactose metabolism (2007) E. Coli Using Reachability Analysis of Hybrid Systems. IET Syst. Biol, 1, pp. 130-148 ;\n Dang, T., Le Guernic, C., Maler, O., Computing reachable states for nonlinear biological models (2011) Theor. Comput. Sci, 412, pp. 2095-2107 ;\n Testylier, R., Dang, T., Analysis of parametric biological models with non-linear dynamics (2012) In Proc. of the First Int.Workshop on Hybrid Systems and Biology, 92, pp. 16-29. , (eds E Bartocci, L Bortolussi). Electron Proc. Theor. Comput. Sci ;\n Open Publishing Association ;\n El-Samad, H., Fazel, M., Liu, X., Papachristodoulou, A., Prajna, S., Stochastic reachability analysis in complex biological networks (2006) In American Control Conf, pp. 6-12. , Minneapolis, MN, 14–16 June ;\n Riley, D., Koutsoukos, X., Riley, K., Verification of biochemical processes using stochastic hybrid systems (2007) IEEE Int. Symp. on Intelligent Control, pp. 100-105 ;\n Parise, F., Valcher, M.E., Lygeros, J., On the reachable set of the controlled gene expression system (2014) IEEE Conf. on Decision and Control, , Los Angeles, CA, USA ;\n Ale, A., Kirk, P., Stumpf, M.P.H., A general moment expansion method for stochastic kinetic models (2013) J. Chem. Phys, 138 ;\n Lakatos, E., Ale, A., Kirk, P., Stumpf, M.P.H., Multivariate moment closure techniques for stochastic kinetic models (2015) J. Chem. Phys, 143 ;\n Fan, S., Geissmann, Q., Lakatos, E., Lukauskas, S., Ale, A., Babtie, A.C., Kirk, P., Stumpf, M.P.H., MEANS: Python package for moment expansion approximation, iNference and simulation (2016) Bioinformatics, 32, pp. 2863-2865 ;\n Kirk, P., Babtie, A.C., Stumpf, M.P.H., Systems biology (Un)certainties (2015) Science, 350, pp. 386-388 ;\n Fukuda, K., From the zonotope construction to the Minkowski addition of convex polytopes (2004) J. Symb. Comput, 38, pp. 1261-1272 ;\n McQuarrie, D.A., Stochastic approach to chemical kinetics (1967) J. Appl. Probab, 4, pp. 413-478 ;\n Ruess, J., Lygeros, J., Moment-based methods for parameter inference and experiment design for stochastic biochemical reaction networks (2015) ACM Trans. Model Comput. Simul, 25, pp. 8:1–8:25 ;\n Schnoerr, D., Sanguinetti, G., Grima, R., Validity conditions for moment closure approximations in stochastic chemical kinetics (2014) J. Chem. Phys, 141 ;\n Schnoerr, D., Sanguinetti, G., Grima, R., Comparison of different moment-closure approximations for stochastic chemical kinetics (2015) J. Chem. Phys, 143 ;\n Szederkényi, G., Lakner, R., Gerzson, M., (2006) Intelligent Control Systems: An Introduction with Examples, , Springer US ;\n Aubin, J.-P., Cellina, A., Differential inclusions: Set-valued maps and viability theory (1984) Grundlehren Der Mathematischenwissenschaften, 264. , (eds A Cherciner, J Coates, SRS Varadhan), Berlin, Heidelberg: Springer ;\n Erguler, K., Stumpf, M.P.H., Practical limits for reverse engineering of dynamical systems: A statistical analysis of sensitivity and parameter inferability in systems biology models (2011) Mol. Biosyst, 7, pp. 1593-1602 ;\n Han, Z., Krogh, B.H., Reachability analysis of nonlinear systems using trajectory piecewise linearized models (2006) American Control Conf, pp. 1505-1510. , Minneapolis, MN, 14–16 June ;\n Munsky, B., Khammash, M., The finite state projection algorithm for the solution of the chemical master equation (2006) J. Chem. Phys, 124 ;\n Ingram, P.J., Stumpf, M., Stark, J., Nonidentifiability of the source of intrinsic noise in gene expression from single-burst data (2008) Plos Comput. Biol, 4 ;\n Tabor, J.J., Levskaya, A., Voigt, C.A., Multichromatic control of gene expression in Escherichia coli (2011) J. Mol. Biol, 405, pp. 315-324 ;\n Komorowski, M., Mikisz, J., Stumpf, M.P.H., Decomposing noise in biochemical signaling systems highlights the role of protein degradation (2013) Biophys. J, 104, pp. 1783-1793 ;\n Lakatos, E., Salehi-Reyhani, A., Barclay, M., Stumpf, M., Klug, D.R., Protein degradation rate is the dominant mechanism accounting for the differences in protein abundance of basal p53 in a human breast and colorectal cancer cell line (2017) Plos ONE, 12 ;\n Anderson, J., Papachristodoulou, A., On validation and invalidation of biological models (2009) BMC Bioinform, 10, p. 132 ;\n Liepe, J., Filippi, S., Komorowski, M., Stumpf, M.P.H., Maximizing the information content of experiments in systems biology (2013) Plos Comput. Biol, 9 ;\n Silk, D., Kirk, P., Barnes, C.P., Toni, T., Stumpf, M.P.H., Model selection in systems biology depends on experimental design (2014) Plos Comput. Biol, 10 ;\n Ferrell, J.E., Jr., Bistability, bifurcations, and Waddington’s epigenetic landscape (2012) Curr. Biol, 22, pp. R458-R466 ;\n Glauche, I., Herberg, M., Roeder, I., Nanog variability and pluripotency regulation of embryonic stem cells—insights from a mathematical model analysis (2010) Plos ONE, 5 ;\n Babtie, A.C., Kirk, P., Stumpf, M.P.H., Topological sensitivity analysis for systems biology (2014) Proc. Natl Acad. Sci. USA, 111, pp. 18507-21812", "hasCitationDuplums" : false, "userChangeableUntil" : "2018-05-17T12:44:46.000+0000", "publishDate" : "2017-10-21T02:33:58.000+0000", "directInstitutesForSort" : "", "ownerAuthorCount" : 5, "ownerInstituteCount" : 38, "directInstituteCount" : 0, "authorCount" : 2, "contributorCount" : 0, "hasQualityFactor" : true, "link" : "/api/publication/26889846", "label" : "Lakatos Eszter et al. Control mechanisms for stochastic biochemical systems via computation of reachable sets. (2017) ROYAL SOCIETY OPEN SCIENCE 2054-5703 4 8", "template" : "