https://m2.mtmt.hu/ hun 2026-07-27 18:48 JournalArticle 2712312 APPROVED true 0 2017-08-25T07:34:21.000+0000 false 2712312 2026-06-18T08:47:50.369+0000 2022-12-03T15:16:59.576+0000 2014-07-28T09:35:25.000+0000 true 215 Szabadics János /api/author/215 Author true 215 2024-06-24T07:58:26.310+0000 2024-06-24T07:58:26.310+0000 true false true 24 24 /api/publicationtype/24 PublicationType 1 true 24 JournalArticle true 10000059 Article true 24 24 /api/publicationtype/24 PublicationType 1 true 24 JournalArticle /api/subtype/10000059 Szakcikk SubType 101 true 10000059 true 1 /api/category/1 Category true 1 Brunner, J Adult-born granule cells mature through two functionally distinct states. true true /api/journal/10031024 REVIEWED true false 10031024 false 10031024 true 2050-084X Journal FOREIGN 3 e03104 e03104 12 2014 Adult-born granule cells (ABGCs) are involved in certain forms of hippocampus-dependent learning and memory. It has been proposed that young but functionally integrated ABGCs (4-weeks-old) specifically contribute to pattern separation functions of the dentate gyrus due to their heightened excitability, whereas old ABGCs (>8-weeks-old) lose these capabilities. Measuring multiple cellular and integrative characteristics of 3-10 weeks old individual ABGCs, we show that ABGCs consist of two functionally distinguishable populations showing highly distinct input integration properties (one group being highly sensitive to narrow input intensity ranges while the other group linearly reports input strength) that are largely independent of the cellular age and maturation stage, suggesting that 'classmate' cells (born during the same period) can contribute to the network with fundamentally different functions. Thus, ABGCs provide two temporally overlapping but functionally distinct neuronal cell populations, adding a novel level of complexity to our understanding of how life-long neurogenesis contributes to adult brain function. true true 2014 (Szabadics János (Celluláris neurofarmako...); 2014.07.28. 11:33:33) true true true false true false GOLD 2026-06-18 true https://doi.org/10.7554/eLife.03104 true 10025655 Vasas Lívia /api/admin/10025655 Admin true 10025655 38 0 38 34 2 37 38 31 35 36 36 32 32 34 4 0 38 34 38 34 0 0 0 Folyóiratcikk Journal Article 24 35 Könyvrészlet Chapter in Book 25 3 Könyv Book 23 0 Egyéb konferenciaközlemény Conference paper 31 0 Egyéb konferenciakötet Conference proceedings 32 0 Oltalmi formák Protection forms 26 0 Disszertáció Thesis 28 0 Egyéb Miscellaneous 29 0 Alkotás Achievement 22 0 Kutatási adat Research data 33 0 Folyóiratcikk Journal Article 24 0 0 0 Könyvrészlet Chapter in Book 25 0 0 0 Könyv Book 23 0 0 0 Egyéb konferenciaközlemény Conference paper 31 0 0 0 Egyéb konferenciakötet Conference proceedings 32 0 0 0 Oltalmi formák Protection forms 26 0 0 0 Disszertáció Thesis 28 0 0 0 Egyéb Miscellaneous 29 0 0 0 Alkotás Achievement 22 0 0 0 Kutatási adat Research data 33 0 0 0 2015 0 6 6 6 6 2016 0 6 4 6 4 2017 0 3 3 3 3 2018 0 7 6 7 6 2019 0 4 4 4 4 2020 0 3 3 3 3 2021 0 2 1 2 1 2022 0 1 1 1 1 2023 0 1 1 1 1 2024 0 1 1 1 1 2025 0 2 2 2 2 2026 0 2 2 2 2 D1 false 215,10014148 false false false 2014-10-26T10:59:20.000+0000 2014-07-28T09:59:20.000+0000 Doktori Iskola (SE); Két-foton Képalkotó Központ (KOKI / GYO); Lendület Celluláris Neurofarmakológia Kutatócso... (KOKI / GYO); MTA Kísérleti Orvostudományi Kutatóintézet 5 33 4 7 0 true Language 10002 /api/language/10002 Angol English true 2 true PersonAuthorship 5397594 /api/authorship/5397594 1 0.14285715 true false Author 10014148 /api/author/10014148 Brunner János true 10014148 true Brunner J true false false AuthorshipType 1 /api/authorshiptype/1 0 true 0 true false 20136853 true PersonAuthorship 5397595 /api/authorship/5397595 2 0.143 true false Author 10045491 /api/author/10045491 Neubrandt Máté true 10045491 true Neubrandt M true false false AuthorshipType 1 /api/authorshiptype/1 0 true 0 true false 20136852 true PersonAuthorship 5397596 /api/authorship/5397596 3 0.143 false false Author 10038708 /api/author/10038708 Van-Weert Szuzan true 10038708 true Van-Weert S true false false AuthorshipType 1 /api/authorshiptype/1 0 true 0 true false 20136851 true PersonAuthorship 5397597 /api/authorship/5397597 4 0.143 false false Author 10039582 /api/author/10039582 Andrási Tibor true 10039582 true Andrasi T true false false AuthorshipType 1 /api/authorshiptype/1 0 true 0 true false 20136850 true PersonAuthorship 5397598 /api/authorship/5397598 5 0.14285715 false false Kleine Borgmann FB true false false AuthorshipType 1 /api/authorshiptype/1 0 true 0 true false 20136849 true PersonAuthorship 5397599 /api/authorship/5397599 6 0.14285715 false false Jessberger S true false false AuthorshipType 1 /api/authorshiptype/1 0 true 0 true false 20136848 true PersonAuthorship 5397600 /api/authorship/5397600 7 0.143 false true true Author 215 /api/author/215 Szabadics János true 215 true Szabadics J true false false AuthorshipType 1 /api/authorshiptype/1 0 true 0 true false 20136847 true PublicationIdentifier 877065 /api/publicationidentifier/877065 PlainSource 6 /api/publicationsource/6 PublicationSourceType 10001 /api/publicationsourcetype/10001 true true true DOI DOI https://doi.org/@@@ true true 6 true GOLD true NO 10.7554/eLife.03104 https://doi.org/10.7554/eLife.03104 false 913855 true PublicationIdentifier 877063 /api/publicationidentifier/877063 PlainSource 1 /api/publicationsource/1 PublicationSourceType 10003 /api/publicationsourcetype/10003 false true true WoS WoS https://www.webofscience.com/wos/woscc/full-record/@@@ true true 1 true false IDENTICAL 000340942500001 https://www.webofscience.com/wos/woscc/full-record/000340942500001 false 1165803 true PublicationIdentifier 877064 /api/publicationidentifier/877064 PlainSource 3 /api/publicationsource/3 PublicationSourceType 10003 /api/publicationsourcetype/10003 false true true Scopus Scopus http://www.scopus.com/record/display.url?origin=inward&eid=2-s2.0-@@@ true true 3 true false NO 84929205568 http://www.scopus.com/record/display.url?origin=inward&eid=2-s2.0-84929205568 false 1624266 true PublicationIdentifier 877066 /api/publicationidentifier/877066 PlainSource 17 /api/publicationsource/17 PublicationSourceType 10003 /api/publicationsourcetype/10003 false true true PubMed PubMed http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db=PubMed&list_uids=@@@&dopt=Abstract true true 17 true false NO 25061223 http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db=PubMed&list_uids=25061223&dopt=Abstract false 913856 true PublicationIdentifier 877067 /api/publicationidentifier/877067 PlainSource 39 /api/publicationsource/39 PublicationSourceType 10006 /api/publicationsourcetype/10006 true true true Teljes dokumentum Full text @@@ true true 39 true GOLD false NO http://elifesciences.org/content/early/2014/07/24/eLife.03104 http://elifesciences.org/content/early/2014/07/24/eLife.03104 false 913939 true Classification 12125 /api/classification/12125 true true Classification 10545 /api/classification/10545 true true Classification 12548 /api/classification/12548 true true Classification 12215 /api/classification/12215 true true SjrRating 11092527 /api/sjrrating/11092527 20 0.0 journal RatingType 10002 /api/ratingtype/10002 sjr true true ClassificationExternal 2701 /api/classificationexternal/2701 true 2701 true D1 DIRECT true true /api/publication/2712312 <div class="JournalArticle Publication long-list"> <div class="authors"> <img title="Forrásközlemény" style="float: left" src="/frontend/resources/grid/publication-core-icon.png"> <div class="autype autype0"> <span class="author-name" mtid="10014148"><a href="/gui2/?type=authors&mode=browse&sel=10014148" target="_blank">Brunner J (<span class="authorship-author-name">Brunner János</span> <span class="authorAux-mtmt"> Neurofarmakológia</span>) </a> </span> <span class="author-affil"><span title="MTA Kísérleti Orvostudományi Kutatóintézet">MTAKOKI</span>/<span title="Gyógyszerkutatási Osztály">GYO</span>/Lendület Celluláris Neurofarmakológia Kutatócsoport; <span title="Semmelweis Egyetem">SE</span>/Doktori Iskola</span> ;&nbsp;&nbsp;&nbsp; <span class="author-name" mtid="10045491"><a href="/gui2/?type=authors&mode=browse&sel=10045491" target="_blank">Neubrandt M<sup>*</sup> (<span class="authorship-author-name">Neubrandt Máté</span> <span class="authorAux-mtmt"> Idegtudomány</span>) </a> </span> <span class="author-affil">MTA Kísérleti Orvostudományi Kutatóintézet</span> ;&nbsp;&nbsp;&nbsp; <span class="author-name" mtid="10038708"><a href="/gui2/?type=authors&mode=browse&sel=10038708" target="_blank">Van-Weert S (<span class="authorship-author-name">Van-Weert Szuzan</span> <span class="authorAux-mtmt"> elektrofiziológia</span>) </a> </span> <span class="author-affil"><span title="MTA Kísérleti Orvostudományi Kutatóintézet">MTAKOKI</span>/<span title="Gyógyszerkutatási Osztály">GYO</span>/Két-foton Képalkotó Központ</span> ;&nbsp;&nbsp;&nbsp; <span class="author-name" mtid="10039582"><a href="/gui2/?type=authors&mode=browse&sel=10039582" target="_blank">Andrasi T (<span class="authorship-author-name">Andrási Tibor</span> <span class="authorAux-mtmt"> Elektrofiziológia</span>) </a> </span> <span class="author-affil"><span title="Semmelweis Egyetem">SE</span>/Doktori Iskola</span> ;&nbsp;&nbsp;&nbsp; <span class="author-name" >Kleine Borgmann FB </span> ;&nbsp;&nbsp;&nbsp; <span class="author-name" >Jessberger S </span> ;&nbsp;&nbsp;&nbsp; <span class="author-name" mtid="215"><a href="/gui2/?type=authors&mode=browse&sel=215" target="_blank">Szabadics J ✉ (<span class="authorship-author-name">Szabadics János</span> <span class="authorAux-mtmt"> Celluláris neurofarmakológia</span>) </a> </span> <span class="author-affil"><span title="MTA Kísérleti Orvostudományi Kutatóintézet">MTAKOKI</span>/<span title="Gyógyszerkutatási Osztály">GYO</span>/Lendület Celluláris Neurofarmakológia Kutatócsoport</span> </div> </div> <div class="title"><a href="/gui2/?mode=browse&params=publication;2712312" target="_blank">Adult-born granule cells mature through two functionally distinct states.</a></div> <div> <span class="journal-title">ELIFE</span> <span class="journal-issn">( <a target="_blank" href="https://portal.issn.org/resource/ISSN/2050-084X">2050-084X</a>)</span>: <span class="journal-volume">3</span> <span class="page"> Paper e03104. 12 p. </span> <span class="year">(2014)</span> </div> <div class="pub-footer"> <span class="language" xmlns="http://www.w3.org/1999/html">Nyelv: Angol | </span> <span class="identifiers"> <span class="id identifier oa_GOLD" title=" Gold "> <a style="color:black" title="10.7554/eLife.03104" target="_blank" href="https://doi.org/10.7554/eLife.03104"> DOI </a> </span> <span class="id identifier oa_none" title="none"> <a style="color:blue" title="000340942500001" target="_blank" href="https://www.webofscience.com/wos/woscc/full-record/000340942500001"> WoS </a> </span> <span class="id identifier oa_none" title="none"> <a style="color:black" title="84929205568" target="_blank" href="http://www.scopus.com/record/display.url?origin=inward&eid=2-s2.0-84929205568"> Scopus </a> </span> <span class="id identifier oa_none" title="none"> <a style="color:black" title="25061223" target="_blank" href="http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db=PubMed&list_uids=25061223&dopt=Abstract"> PubMed </a> </span> <span class="id identifier oa_GOLD" title=" Gold "> <a style="color:black" title="http://elifesciences.org/content/early/2014/07/24/eLife.03104" target="_blank" href="http://elifesciences.org/content/early/2014/07/24/eLife.03104"> Teljes dokumentum </a> </span> </span> <OnlyViewableByAuthor><div class="ratings"> <div class="journal-subject">Folyóirat szakterülete: Scopus - Biochemistry, Genetics and Molecular Biology (miscellaneous)&nbsp;&nbsp;&nbsp;SJR indikátor:&nbsp;D1</div> <div class="journal-subject">Folyóirat szakterülete: Scopus - Medicine (miscellaneous)&nbsp;&nbsp;&nbsp;SJR indikátor:&nbsp;D1</div> <div class="journal-subject">Folyóirat szakterülete: Scopus - Neuroscience (miscellaneous)&nbsp;&nbsp;&nbsp;SJR indikátor:&nbsp;D1</div> <div class="journal-subject">Folyóirat szakterülete: Scopus - Immunology and Microbiology (miscellaneous)&nbsp;&nbsp;&nbsp;SJR indikátor:&nbsp;Q1</div> </div></OnlyViewableByAuthor> <div class="publication-citation" style="margin-left: 0.5cm;"> <span title="Nyilvános idézőközlemények összesen, említések nélkül" class="citingPub-count">Nyilvános idéző összesen: 38</span> | Független: 34 | Függő: 4 | Nem jelölt: 0 | WoS jelölt: 31 | Scopus jelölt:&nbsp;35 | WoS/Scopus jelölt:&nbsp;36 | DOI jelölt:&nbsp;38 </div> <div class="mtid"><span class="long-pub-mtid">Közlemény: 2712312</span> | <span class="status-data status-APPROVED"> Nyilvános </span> <span class="oldId">Régi azonosító: 2712312</span> | Forrás | <span class="type-subtype">Folyóiratcikk ( Szakcikk ) </span> | <span class="pub-category">Tudományos</span> | <span class="publication-sourceOfData">MEDLINE</span> </div> <div class="lastModified">Utolsó módosítás: 2022.12.03. 16:16 Turek Márta (KOKI admin 4) </div> </div></div>