{ "labelLang" : "hun", "responseDate" : "2024-03-29 00:41", "content" : { "otype" : "JournalArticle", "mtid" : 27083545, "status" : "APPROVED", "published" : true, "comment" : "Cited By :9 \n Export Date: 11 June 2020 \n Correspondence Address: Mohamed, L.A.; Jefferson Weinberg ALS Center, Vickie and Jack Farber Institute for Neuroscience, Department of Neuroscience, Thomas Jefferson University Hospitals, 900 Walnut Street, United States; email: Loqman.Mohamed.Science@gmail.com \n Chemicals/CAS: acetylcysteine, 616-91-1; arundic acid, 185517-21-9; ceftriaxone, 73384-59-5, 74578-69-1; creatine, 57-00-1; dexpramipexole, 104632-28-2, 104632-27-1, 908244-04-2; fingolimod, 162359-56-0; gabapentin, 60142-96-3; glatiramer, 147245-92-9, 28704-27-0; glutathione, 70-18-8; ibudilast, 50847-11-5; lamotrigine, 84057-84-1; levacecarnine, 3040-38-8, 5080-50-2; masitinib, 790299-79-5; mecobalamin, 13422-55-4; memantine, 19982-08-2, 41100-52-1, 51052-62-1; minocycline, 10118-90-8, 11006-27-2, 13614-98-7; nimodipine, 66085-59-4; norphenazone, 89-25-8; olesoxime, 22033-87-0; omigapil, 181296-84-4; ozanezumab, 1310680-64-8; pioglitazone, 105355-27-9, 111025-46-8; rasagiline, 136236-51-6, 161735-79-1, 1875-50-9; riluzole, 1744-22-5; talampanel, 161832-65-1, 161832-67-3; tauroursodeoxycholic acid, 14605-22-2; threonine, 36676-50-3, 72-19-5; tirasemtiv, 1005491-05-3; tocilizumab, 375823-41-9; topiramate, 97240-79-4; ABC transporter subfamily B, 149200-37-3, 208997-77-7; ABCB1 protein, human; ATP Binding Cassette Transporter, Sub-Family B; ATP-Binding Cassette, Sub-Family B, Member 1 \n Tradenames: ab 1010; avp 923; cgp 3466b; ck 2017357; epi 589; gm 604; gsk 1223249; kns 760704; mci 186; mn 166; np 001; ono 2506; rns 60; sb 509; snn 0029; tch 346; tro 19622; tw 001; vm 202 \n Funding details: Target ALS \n Funding details: National Institutes of Health, NIH, RO1-NS074886 \n Funding text 1: This work was supported by the National Institutes of Health (grant number RO1-NS074886 to DT) and Target ALS (to DT and PP).", "unhandledTickets" : 0, "oldTimestamp" : "2018-02-11T16:06:31.000+0000", "deleted" : false, "oldId" : 17083545, "lastRefresh" : "2020-06-11T14:28:22.710+0000", "lastModified" : "2018-02-11T16:06:31.000+0000", "created" : "2018-01-14T05:41:09.000+0000", "creator" : { "otype" : "Author", "mtid" : 10007780, "link" : "/api/author/10007780", "label" : "Szabó Gábor (Sejtbiológia)", "familyName" : "Szabó", "givenName" : "Gábor", "published" : true, "oldId" : 10007780, "snippet" : true }, "core" : false, "citation" : true, "publicationPending" : false, "type" : { "otype" : "PublicationType", "mtid" : 24, "link" : "/api/publicationtype/24", "label" : "Folyóiratcikk", "code" : 24, "otypeName" : "JournalArticle", "listPosition" : 1, "published" : true, "oldId" : 24, "snippet" : true }, "subType" : { "otype" : "SubType", "mtid" : 1134514, "link" : "/api/subtype/1134514", "label" : "Összefoglaló cikk (Folyóiratcikk)", "name" : "Összefoglaló cikk", "nameEng" : "Survey paper", "docType" : { "otype" : "PublicationType", "mtid" : 24, "link" : "/api/publicationtype/24", "label" : "Folyóiratcikk", "code" : 24, "otypeName" : "JournalArticle", "listPosition" : 1, "published" : true, "oldId" : 24, "snippet" : true }, "listPosition" : 102, "published" : true, "oldId" : 1134514, "snippet" : true }, "category" : { "otype" : "Category", "mtid" : 1, "link" : "/api/category/1", "label" : "Tudományos", "published" : true, "oldId" : 1, "snippet" : true }, "languages" : [ { "otype" : "Language", "mtid" : 10002, "link" : "/api/language/10002", "label" : "Angol", "name" : "Angol", "nameEng" : "English", "published" : true, "oldId" : 2, "snippet" : true } ], "firstAuthor" : "Mohamed, Loqman A", "authorships" : [ { "otype" : "PersonAuthorship", "mtid" : 74588818, "link" : "/api/authorship/74588818", "label" : "Mohamed, Loqman A", "listPosition" : 1, "share" : 0.0, "first" : true, "last" : false, "familyName" : "Mohamed", "givenName" : "Loqman A", "authorTyped" : true, "editorTyped" : false, "otherTyped" : false, "type" : { "otype" : "AuthorshipType", "mtid" : 1, "link" : "/api/authorshiptype/1", "label" : "Szerző", "code" : 0, "published" : true, "oldId" : 0, "snippet" : true }, "published" : false, "oldId" : 152330135, "snippet" : true }, { "otype" : "PersonAuthorship", "mtid" : 74588819, "link" : "/api/authorship/74588819", "label" : "Markandaiah, Shashirekha", "listPosition" : 2, "share" : 0.0, "first" : false, "last" : false, "familyName" : "Markandaiah", "givenName" : "Shashirekha", "authorTyped" : true, "editorTyped" : false, "otherTyped" : false, "type" : { "otype" : "AuthorshipType", "mtid" : 1, "link" : "/api/authorshiptype/1", "label" : "Szerző", "code" : 0, "published" : true, "oldId" : 0, "snippet" : true }, "published" : false, "oldId" : 152330134, "snippet" : true }, { "otype" : "PersonAuthorship", "mtid" : 74588820, "link" : "/api/authorship/74588820", "label" : "Bonanno, Silvia", "listPosition" : 3, "share" : 0.0, "first" : false, "last" : false, "familyName" : "Bonanno", "givenName" : "Silvia", "authorTyped" : true, "editorTyped" : false, "otherTyped" : false, "type" : { "otype" : "AuthorshipType", "mtid" : 1, "link" : "/api/authorshiptype/1", "label" : "Szerző", "code" : 0, "published" : true, "oldId" : 0, "snippet" : true }, "published" : false, "oldId" : 152330133, "snippet" : true }, { "otype" : "PersonAuthorship", "mtid" : 74588821, "link" : "/api/authorship/74588821", "label" : "Pasinelli, Piera", "listPosition" : 4, "share" : 0.0, "first" : false, "last" : false, "familyName" : "Pasinelli", "givenName" : "Piera", "authorTyped" : true, "editorTyped" : false, "otherTyped" : false, "type" : { "otype" : "AuthorshipType", "mtid" : 1, "link" : "/api/authorshiptype/1", "label" : "Szerző", "code" : 0, "published" : true, "oldId" : 0, "snippet" : true }, "published" : false, "oldId" : 152330132, "snippet" : true }, { "otype" : "PersonAuthorship", "mtid" : 74588822, "link" : "/api/authorship/74588822", "label" : "Trotti, Davide", "listPosition" : 5, "share" : 0.0, "first" : false, "last" : true, "familyName" : "Trotti", "givenName" : "Davide", "authorTyped" : true, "editorTyped" : false, "otherTyped" : false, "type" : { "otype" : "AuthorshipType", "mtid" : 1, "link" : "/api/authorshiptype/1", "label" : "Szerző", "code" : 0, "published" : true, "oldId" : 0, "snippet" : true }, "published" : false, "oldId" : 152330131, "snippet" : true } ], "title" : "Blood-Brain Barrier Driven Pharmacoresistance in Amyotrophic Lateral Sclerosis and Challenges for Effective Drug Therapies", "identifiers" : [ { "otype" : "PublicationIdentifier", "mtid" : 13428103, "link" : "/api/publicationidentifier/13428103", "label" : "DOI: 10.1208/s12248-017-0120-6", "source" : { "otype" : "PlainSource", "mtid" : 6, "link" : "/api/publicationsource/6", "label" : "DOI", "type" : { "otype" : "PublicationSourceType", "mtid" : 10001, "link" : "/api/publicationsourcetype/10001", "label" : "DOI", "mayHaveOa" : true, "published" : true, "snippet" : true }, "name" : "DOI", "nameEng" : "DOI", "linkPattern" : "https://doi.org/@@@", "publiclyVisible" : true, "published" : true, "oldId" : 6, "snippet" : true }, "validState" : "IDENTICAL", "idValue" : "10.1208/s12248-017-0120-6", "realUrl" : "https://doi.org/10.1208%2Fs12248-017-0120-6", "published" : false, "oldId" : 16348974, "snippet" : true }, { "otype" : "PublicationIdentifier", "mtid" : 13428102, "link" : "/api/publicationidentifier/13428102", "label" : "WoS: 000415057700007", "source" : { "otype" : "PlainSource", "mtid" : 1, "link" : "/api/publicationsource/1", "label" : "WoS", "type" : { "otype" : "PublicationSourceType", "mtid" : 10003, "link" : "/api/publicationsourcetype/10003", "label" : "Indexelő adatbázis", "mayHaveOa" : false, "published" : true, "snippet" : true }, "name" : "WoS", "nameEng" : "WoS", "linkPattern" : "http://gateway.isiknowledge.com/gateway/Gateway.cgi?&GWVersion=2&SrcAuth=CustomerName&SrcApp=CustomerName&DestLinkType=FullRecord&KeyUT=@@@&DestApp=WOS", "publiclyVisible" : true, "published" : true, "oldId" : 1, "snippet" : true }, "validState" : "IDENTICAL", "idValue" : "000415057700007", "realUrl" : "http://gateway.isiknowledge.com/gateway/Gateway.cgi?&GWVersion=2&SrcAuth=CustomerName&SrcApp=CustomerName&DestLinkType=FullRecord&KeyUT=000415057700007&DestApp=WOS", "published" : false, "oldId" : 16348973, "snippet" : true }, { "otype" : "PublicationIdentifier", "mtid" : 14731936, "link" : "/api/publicationidentifier/14731936", "label" : "Scopus: 85026819371", "source" : { "otype" : "PlainSource", "mtid" : 3, "link" : "/api/publicationsource/3", "label" : "Scopus", "type" : { "otype" : "PublicationSourceType", "mtid" : 10003, "link" : "/api/publicationsourcetype/10003", "label" : "Indexelő adatbázis", "mayHaveOa" : false, "published" : true, "snippet" : true }, "name" : "Scopus", "linkPattern" : "http://www.scopus.com/record/display.url?origin=inward&eid=2-s2.0-@@@", "publiclyVisible" : true, "published" : true, "oldId" : 3, "snippet" : true }, "validState" : "IDENTICAL", "idValue" : "85026819371", "realUrl" : "http://www.scopus.com/record/display.url?origin=inward&eid=2-s2.0-85026819371", "published" : false, "oldId" : 17173703, "snippet" : true }, { "otype" : "PublicationIdentifier", "mtid" : 16966124, "link" : "/api/publicationidentifier/16966124", "label" : "PubMed: 28779378", "source" : { "otype" : "PlainSource", "mtid" : 17, "link" : "/api/publicationsource/17", "label" : "PubMed", "type" : { "otype" : "PublicationSourceType", "mtid" : 10003, "link" : "/api/publicationsourcetype/10003", "label" : "Indexelő adatbázis", "mayHaveOa" : false, "published" : true, "snippet" : true }, "name" : "PubMed", "nameEng" : "PubMed", "linkPattern" : "http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db=PubMed&list_uids=@@@&dopt=Abstract", "publiclyVisible" : true, "published" : true, "oldId" : 17, "snippet" : true }, "validState" : "IDENTICAL", "idValue" : "28779378", "realUrl" : "http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db=PubMed&list_uids=28779378&dopt=Abstract", "published" : false, "snippet" : true } ], "journal" : { "otype" : "Journal", "mtid" : 10002853, "link" : "/api/journal/10002853", "label" : "AAPS JOURNAL 1550-7416", "eIssn" : "1550-7416", "reviewType" : "REVIEWED", "noIF" : false, "sciIndexed" : true, "scopusIndexed" : true, "lang" : "FOREIGN", "hungarian" : false, "published" : true, "oldId" : 10002853, "snippet" : true }, "volume" : "19", "issue" : "6", "firstPage" : "1600", "lastPage" : "1614", "firstPageOrInternalIdForSort" : "1600", "pageLength" : 15, "publishedYear" : 2017, "digital" : null, "printed" : null, "sourceYear" : 2018, "foreignEdition" : true, "foreignLanguage" : true, "fullPublication" : true, "conferencePublication" : false, "nationalOrigin" : null, "missingAuthor" : false, "oaType" : "NONE", "oaCheckDate" : "2020-06-11", "oaFree" : false, "citationCount" : 0, "citationCountUnpublished" : 0, "citationCountWoOther" : 0, "independentCitCountWoOther" : 0, "doiCitationCount" : 0, "wosCitationCount" : 0, "scopusCitationCount" : 0, "independentCitationCount" : 0, "unhandledCitationCount" : 0, "citingPubCount" : 0, "independentCitingPubCount" : 0, "unhandledCitingPubCount" : 0, "citedPubCount" : 2, "citedCount" : 2, "ratings" : [ { "otype" : "SjrRating", "mtid" : 10720852, "link" : "/api/sjrrating/10720852", "label" : "sjr:Q1 (2017) Scopus - Pharmaceutical Science AAPS JOURNAL 1550-7416", "listPos" : 23, "rankValue" : 0.24, "type" : "journal", "ratingType" : { "otype" : "RatingType", "mtid" : 10002, "link" : "/api/ratingtype/10002", "label" : "sjr", "code" : "sjr", "published" : true, "snippet" : true }, "subject" : { "otype" : "ClassificationExternal", "mtid" : 3003, "link" : "/api/classificationexternal/3003", "label" : "Scopus - Pharmaceutical Science", "published" : true, "oldId" : 3003, "snippet" : true }, "ranking" : "Q1", "calculation" : "DIRECT", "published" : true, "snippet" : true } ], "ratingsForSort" : "Q1", "hasCitationDuplums" : false, "userChangeableUntil" : "2019-01-31T22:59:00.000+0000", "publishDate" : "2018-01-14T05:41:09.000+0000", "directInstitutesForSort" : "", "ownerAuthorCount" : 6, "ownerInstituteCount" : 18, "directInstituteCount" : 0, "authorCount" : 5, "contributorCount" : 0, "hasQualityFactor" : true, "link" : "/api/publication/27083545", "label" : "Mohamed Loqman A et al. Blood-Brain Barrier Driven Pharmacoresistance in Amyotrophic Lateral Sclerosis and Challenges for Effective Drug Therapies. (2017) AAPS JOURNAL 1550-7416 19 6 1600-1614", "template" : "