ntensive care is one of the most challenging areas of modern medicine. Maintenance
of glucose levels in intensive care unit (ICU) patients via control of insulin inputs
is currently an active research field. The current paper presents the analysis of
postmodern and nonlinear control methods for tight glycaemic control (TGC) under intensive
care. Using a clinically validated ICU metabolic system model's redefined version,
an H∞-type robust controller is proposed and compared with a non-conservative complex
µ-synthesis method, where robust stability and nominal performance is met under multiplicative
uncertainty. The model is rewritten in affine parameter varying form by choosing scheduling
parameters and a quasi Affine Linear Parameter Varying (qALPV) controller is designed
assuring performance and stability requirements. Closed loop simulation results are
tested under MATLAB.
