{ "labelLang" : "hun", "responseDate" : "2024-03-29 14:37", "content" : { "otype" : "BookChapter", "mtid" : 32769128, "status" : "ADMIN_APPROVED", "published" : true, "comment" : "Department of Radiation Oncology, Odette Cancer Centre, Sunnybrook Health Sciences Centre, University of Toronto, 2075 Bayview Ave, M4N 3M5 Toronto, ON, Canada \n Department of Medical Oncology, Odette Cancer Centre, Sunnybrook Health Sciences Centre, University of Toronto, 2075 Bayview Ave, M4N 3M5 Toronto, ON, Canada \n Export Date: 1 April 2022 \n Correspondence Address: Chow, E.; Department of Radiation Oncology, Odette Cancer Centre, Sunnybrook Health Sciences Centre, 2075 Bayview Ave, M4N 3M5 Toronto, ON, Canada; email: Edward.Chow@sunnybrook.ca \n Chemicals/CAS: clodronic acid, 10596-23-3, 22560-50-5; ibandronic acid, 114084-78-5, 138844-81-2, 138926-19-9; morphine, 52-26-6, 57-27-2; pamidronic acid, 40391-99-9, 57248-88-1; zoledronic acid, 118072-93-8, 131654-46-1, 165800-06-6, 165800-07-7", "unhandledTickets" : 0, "deleted" : false, "lastRefresh" : "2023-03-02T14:24:13.596+0000", "lastModified" : "2022-04-01T17:54:24.925+0000", "created" : "2022-04-01T17:49:06.097+0000", "creator" : { "otype" : "Admin", "mtid" : 10026258, "link" : "/api/admin/10026258", "label" : "Nemesvári Zoltánné (SZTE admin5)", "familyName" : "Nemesvári", "givenName" : "Zoltánné", "published" : true, "oldId" : 10026258, "snippet" : true }, "lastDuplumSearch" : "2022-08-02T14:34:32.851+0000", "adminApproved" : "2022-04-01T17:54:24.949+0000", "adminApprover" : { "otype" : "Admin", "mtid" : 10026258, "link" : "/api/admin/10026258", "label" : "Nemesvári Zoltánné (SZTE admin5)", "familyName" : "Nemesvári", "givenName" : "Zoltánné", "published" : true, "oldId" : 10026258, "snippet" : true }, "core" : false, "citation" : true, "publicationPending" : false, "type" : { "otype" : "PublicationType", "mtid" : 25, "link" : "/api/publicationtype/25", "label" : "Könyvrészlet", "code" : 25, "otypeName" : "BookChapter", "listPosition" : 2, "published" : true, "oldId" : 25, "snippet" : true }, "subType" : { "otype" : "SubType", "mtid" : 10000398, "link" : "/api/subtype/10000398", "label" : "Könyvfejezet (Könyvrészlet)", "name" : "Könyvfejezet", "nameEng" : "Chapter", "docType" : { "otype" : "PublicationType", "mtid" : 25, "link" : "/api/publicationtype/25", "label" : "Könyvrészlet", "code" : 25, "otypeName" : "BookChapter", "listPosition" : 2, "published" : true, "oldId" : 25, "snippet" : true }, "listPosition" : 220, "published" : true, "oldId" : 10000398, "snippet" : true }, "category" : { "otype" : "Category", "mtid" : 1, "link" : "/api/category/1", "label" : "Tudományos", "published" : true, "oldId" : 1, "snippet" : true }, "languages" : [ { "otype" : "Language", "mtid" : 10002, "link" : "/api/language/10002", "label" : "Angol", "name" : "Angol", "nameEng" : "English", "published" : true, "oldId" : 2, "snippet" : true } ], "firstAuthor" : "Poon, M.", "authorships" : [ { "otype" : "PersonAuthorship", "mtid" : 101242408, "link" : "/api/authorship/101242408", "label" : "Poon, M.", "listPosition" : 1, "share" : 0.25, "first" : true, "last" : false, "corresponding" : false, "familyName" : "Poon", "givenName" : "M.", "authorTyped" : true, "editorTyped" : false, "otherTyped" : false, "type" : { "otype" : "AuthorshipType", "mtid" : 1, "link" : "/api/authorshiptype/1", "label" : "Szerző", "code" : 0, "published" : true, "oldId" : 0, "snippet" : true }, "published" : false, "snippet" : true }, { "otype" : "PersonAuthorship", "mtid" : 101242409, "link" : "/api/authorship/101242409", "label" : "Zeng, L.", "listPosition" : 2, "share" : 0.25, "first" : false, "last" : false, "corresponding" : false, "familyName" : "Zeng", "givenName" : "L.", "authorTyped" : true, "editorTyped" : false, "otherTyped" : false, "type" : { "otype" : "AuthorshipType", "mtid" : 1, "link" : "/api/authorshiptype/1", "label" : "Szerző", "code" : 0, "published" : true, "oldId" : 0, "snippet" : true }, "published" : false, "snippet" : true }, { "otype" : "PersonAuthorship", "mtid" : 101242410, "link" : "/api/authorship/101242410", "label" : "Emmenegger, U.", "listPosition" : 3, "share" : 0.25, "first" : false, "last" : false, "corresponding" : false, "familyName" : "Emmenegger", "givenName" : "U.", "authorTyped" : true, "editorTyped" : false, "otherTyped" : false, "type" : { "otype" : "AuthorshipType", "mtid" : 1, "link" : "/api/authorshiptype/1", "label" : "Szerző", "code" : 0, "published" : true, "oldId" : 0, "snippet" : true }, "published" : false, "snippet" : true }, { "otype" : "PersonAuthorship", "mtid" : 101242411, "link" : "/api/authorship/101242411", "label" : "Chow, E. ✉", "listPosition" : 4, "share" : 0.25, "first" : false, "last" : true, "corresponding" : true, "familyName" : "Chow", "givenName" : "E.", "authorTyped" : true, "editorTyped" : false, "otherTyped" : false, "type" : { "otype" : "AuthorshipType", "mtid" : 1, "link" : "/api/authorshiptype/1", "label" : "Szerző", "code" : 0, "published" : true, "oldId" : 0, "snippet" : true }, "published" : false, "snippet" : true } ], "title" : "Outcome Measures in Bone Metastases Clinical Trials", "identifiers" : [ { "otype" : "PublicationIdentifier", "mtid" : 20846312, "link" : "/api/publicationidentifier/20846312", "label" : "DOI: 10.1007/978-94-007-7569-5_23", "source" : { "otype" : "PlainSource", "mtid" : 6, "link" : "/api/publicationsource/6", "label" : "DOI", "type" : { "otype" : "PublicationSourceType", "mtid" : 10001, "link" : "/api/publicationsourcetype/10001", "label" : "DOI", "mayHaveOa" : true, "published" : true, "snippet" : true }, "name" : "DOI", "nameEng" : "DOI", "linkPattern" : "https://doi.org/@@@", "publiclyVisible" : true, "published" : true, "oldId" : 6, "snippet" : true }, "validState" : "IDENTICAL", "idValue" : "10.1007/978-94-007-7569-5_23", "realUrl" : "https://doi.org/10.1007/978-94-007-7569-5_23", "published" : false, "snippet" : true }, { "otype" : "PublicationIdentifier", "mtid" : 20846311, "link" : "/api/publicationidentifier/20846311", "label" : "Scopus: 84896886066", "source" : { "otype" : "PlainSource", "mtid" : 3, "link" : "/api/publicationsource/3", "label" : "Scopus", "type" : { "otype" : "PublicationSourceType", "mtid" : 10003, "link" : "/api/publicationsourcetype/10003", "label" : "Indexelő adatbázis", "mayHaveOa" : false, "published" : true, "snippet" : true }, "name" : "Scopus", "linkPattern" : "http://www.scopus.com/record/display.url?origin=inward&eid=2-s2.0-@@@", "publiclyVisible" : true, "published" : true, "oldId" : 3, "snippet" : true }, "validState" : "IDENTICAL", "idValue" : "84896886066", "realUrl" : "http://www.scopus.com/record/display.url?origin=inward&eid=2-s2.0-84896886066", "published" : false, "snippet" : true } ], "firstPage" : "419", "lastPage" : "439", "firstPageOrInternalIdForSort" : "419", "pageLength" : 21, "publishedYear" : 2014, "abstractText" : "The most common site of metastatic disease in advanced cancer is bone. Management of bone metastases is becoming increasingly multi-disciplinary in nature and many advances have been made to both localized and systemic therapies. With the expanding body of literature, it is important to recognize that there is still extensive variation in response or outcome definitions, and that standardization and consensus of how to analyze clinical data is needed. This will ensure that therapy options can be accurately monitored for both their benefits and adverse effects and allow for better cross-study comparisons. This chapter will outline the outcomes of interest in radiation and bone-modifying agent clinical trials, as well as introduce outcomes used in pain flare and radiation induced nausea and vomiting assessment. The evaluation of pain response in previous trials and the establishment of the International Bone Metastases Consensus Working Party endpoints will also be presented. © Springer Science+Business Media Dordrecht 2014.", "keywords" : [ { "otype" : "Keyword", "mtid" : 1699, "link" : "/api/keyword/1699", "label" : "ARTICLE", "published" : true, "oldId" : 1699, "snippet" : true }, { "otype" : "Keyword", "mtid" : 2032, "link" : "/api/keyword/2032", "label" : "MORPHINE", "published" : true, "oldId" : 2032, "snippet" : true }, { "otype" : "Keyword", "mtid" : 2034, "link" : "/api/keyword/2034", "label" : "ANALGESIA", "published" : true, "oldId" : 2034, "snippet" : true }, { "otype" : "Keyword", "mtid" : 3122, "link" : "/api/keyword/3122", "label" : "human", "published" : true, "oldId" : 3122, "snippet" : true }, { "otype" : "Keyword", "mtid" : 4156, "link" : "/api/keyword/4156", "label" : "Quality of Life", "published" : true, "oldId" : 4156, "snippet" : true }, { "otype" : "Keyword", "mtid" : 4557, "link" : "/api/keyword/4557", "label" : "treatment response", "published" : true, "oldId" : 4557, "snippet" : true }, { "otype" : "Keyword", "mtid" : 4600, "link" : "/api/keyword/4600", "label" : "priority journal", "published" : true, "oldId" : 4600, "snippet" : true }, { "otype" : "Keyword", "mtid" : 13962, "link" : "/api/keyword/13962", "label" : "Consensus", "published" : true, "oldId" : 13962, "snippet" : true }, { "otype" : "Keyword", "mtid" : 14217, "link" : "/api/keyword/14217", "label" : "outcome assessment", "published" : true, "oldId" : 14217, "snippet" : true }, { "otype" : "Keyword", "mtid" : 14471, "link" : "/api/keyword/14471", "label" : "Clinical Trials", "published" : true, "oldId" : 14471, "snippet" : true }, { "otype" : "Keyword", "mtid" : 19389, "link" : "/api/keyword/19389", "label" : "HYPERCALCEMIA", "published" : true, "oldId" : 19389, "snippet" : true }, { "otype" : "Keyword", "mtid" : 19916, "link" : "/api/keyword/19916", "label" : "bisphosphonic acid derivative", "published" : true, "oldId" : 19916, "snippet" : true }, { "otype" : "Keyword", "mtid" : 20203, "link" : "/api/keyword/20203", "label" : "follow up", "published" : true, "oldId" : 20203, "snippet" : true }, { "otype" : "Keyword", "mtid" : 20219, "link" : "/api/keyword/20219", "label" : "cancer radiotherapy", "published" : true, "oldId" : 20219, "snippet" : true }, { "otype" : "Keyword", "mtid" : 1001253, "link" : "/api/keyword/1001253", "label" : "morbidity", "published" : true, "oldId" : 1001253, "snippet" : true }, { "otype" : "Keyword", "mtid" : 1005603, "link" : "/api/keyword/1005603", "label" : "nausea and vomiting", "published" : true, "oldId" : 1005603, "snippet" : true }, { "otype" : "Keyword", "mtid" : 1008670, "link" : "/api/keyword/1008670", "label" : "practice guideline", "published" : true, "oldId" : 1008670, "snippet" : true }, { "otype" : "Keyword", "mtid" : 1009119, "link" : "/api/keyword/1009119", "label" : "named inventories, questionnaires and rating scales", "published" : true, "oldId" : 1009119, "snippet" : true }, { "otype" : "Keyword", "mtid" : 1009143, "link" : "/api/keyword/1009143", "label" : "self evaluation", "published" : true, "oldId" : 1009143, "snippet" : true }, { "otype" : "Keyword", "mtid" : 1010011, "link" : "/api/keyword/1010011", "label" : "fractionation", "published" : true, "oldId" : 1010011, "snippet" : true }, { "otype" : "Keyword", "mtid" : 1011026, "link" : "/api/keyword/1011026", "label" : "zoledronic acid", "published" : true, "oldId" : 1011026, "snippet" : true }, { "otype" : "Keyword", "mtid" : 1024748, "link" : "/api/keyword/1024748", "label" : "visual analog scale", "published" : true, "oldId" : 1024748, "snippet" : true }, { "otype" : "Keyword", "mtid" : 1029707, "link" : "/api/keyword/1029707", "label" : "cancer pain", "published" : true, "oldId" : 1029707, "snippet" : true }, { "otype" : "Keyword", "mtid" : 1029711, "link" : "/api/keyword/1029711", "label" : "pain assessment", "published" : true, "oldId" : 1029711, "snippet" : true }, { "otype" : "Keyword", "mtid" : 1034626, "link" : "/api/keyword/1034626", "label" : "health care personnel", "published" : true, "oldId" : 1034626, "snippet" : true }, { "otype" : "Keyword", "mtid" : 1034793, "link" : "/api/keyword/1034793", "label" : "patient attitude", "published" : true, "oldId" : 1034793, "snippet" : true }, { "otype" : "Keyword", "mtid" : 1040950, "link" : "/api/keyword/1040950", "label" : "daily life activity", "published" : true, "oldId" : 1040950, "snippet" : true }, { "otype" : "Keyword", "mtid" : 1043791, "link" : "/api/keyword/1043791", "label" : "patient assessment", "published" : true, "oldId" : 1043791, "snippet" : true }, { "otype" : "Keyword", "mtid" : 1046555, "link" : "/api/keyword/1046555", "label" : "bone metastasis", "published" : true, "oldId" : 1046555, "snippet" : true }, { "otype" : "Keyword", "mtid" : 1047080, "link" : "/api/keyword/1047080", "label" : "side effects", "published" : true, "oldId" : 1047080, "snippet" : true }, { "otype" : "Keyword", "mtid" : 1052333, "link" : "/api/keyword/1052333", "label" : "pathologic fracture", "published" : true, "oldId" : 1052333, "snippet" : true }, { "otype" : "Keyword", "mtid" : 1060751, "link" : "/api/keyword/1060751", "label" : "clinical trial (topic)", "published" : true, "oldId" : 1060751, "snippet" : true }, { "otype" : "Keyword", "mtid" : 1069561, "link" : "/api/keyword/1069561", "label" : "randomized controlled trial (topic)", "published" : true, "oldId" : 1069561, "snippet" : true }, { "otype" : "Keyword", "mtid" : 1070652, "link" : "/api/keyword/1070652", "label" : "bone pain", "published" : true, "oldId" : 1070652, "snippet" : true }, { "otype" : "Keyword", "mtid" : 1074046, "link" : "/api/keyword/1074046", "label" : "radiation dose fractionation", "published" : true, "oldId" : 1074046, "snippet" : true }, { "otype" : "Keyword", "mtid" : 1077550, "link" : "/api/keyword/1077550", "label" : "cancer palliative therapy", "published" : true, "oldId" : 1077550, "snippet" : true }, { "otype" : "Keyword", "mtid" : 1101252, "link" : "/api/keyword/1101252", "label" : "pamidronic acid", "published" : true, "oldId" : 1101252, "snippet" : true }, { "otype" : "Keyword", "mtid" : 1101296, "link" : "/api/keyword/1101296", "label" : "ibandronic acid", "published" : true, "oldId" : 1101296, "snippet" : true }, { "otype" : "Keyword", "mtid" : 1159088, "link" : "/api/keyword/1159088", "label" : "clodronic acid", "published" : true, "oldId" : 1159088, "snippet" : true }, { "otype" : "Keyword", "mtid" : 1186972, "link" : "/api/keyword/1186972", "label" : "outcome measures", "published" : true, "oldId" : 1186972, "snippet" : true }, { "otype" : "Keyword", "mtid" : 1207937, "link" : "/api/keyword/1207937", "label" : "phase 3 clinical trial (topic)", "published" : true, "oldId" : 1207937, "snippet" : true }, { "otype" : "Keyword", "mtid" : 1502782, "link" : "/api/keyword/1502782", "label" : "telephone interview", "published" : true, "snippet" : true }, { "otype" : "Keyword", "mtid" : 1511325, "link" : "/api/keyword/1511325", "label" : "spinal cord compression", "published" : true, "snippet" : true }, { "otype" : "Keyword", "mtid" : 1528660, "link" : "/api/keyword/1528660", "label" : "Brief Pain Inventory", "published" : true, "snippet" : true }, { "otype" : "Keyword", "mtid" : 1605969, "link" : "/api/keyword/1605969", "label" : "Bone metastases", "published" : true, "snippet" : true }, { "otype" : "Keyword", "mtid" : 1829013, "link" : "/api/keyword/1829013", "label" : "Clinical endpoints", "published" : true, "snippet" : true }, { "otype" : "Keyword", "mtid" : 2613570, "link" : "/api/keyword/2613570", "label" : "verbal descriptor scale", "published" : true, "snippet" : true } ], "digital" : null, "printed" : null, "sourceYear" : 2022, "foreignEdition" : null, "foreignLanguage" : true, "fullPublication" : true, "conferencePublication" : false, "nationalOrigin" : null, "missingAuthor" : false, "oaType" : "NONE", "oaCheckDate" : "2023-03-02", "oaFree" : false, "citationCount" : 0, "citationCountUnpublished" : 0, "citationCountWoOther" : 0, "independentCitCountWoOther" : 0, "doiCitationCount" : 0, "wosCitationCount" : 0, "scopusCitationCount" : 0, "independentCitationCount" : 0, "unhandledCitationCount" : 0, "citingPubCount" : 0, "independentCitingPubCount" : 0, "unhandledCitingPubCount" : 0, "citedPubCount" : 1, "citedCount" : 1, "references" : [ { "otype" : "Reference", "mtid" : 29489049, "link" : "/api/reference/29489049", "label" : "1. Olver, I., Molassiotis, A., Aapro, M., Antiemetic research: Future directions (2011) Support Care Cancer, 19 (SUPPL.), pp. 1S49-1S55", "listPosition" : 1, "published" : false, "snippet" : true }, { "otype" : "Reference", "mtid" : 29489048, "link" : "/api/reference/29489048", "label" : "2. Maranzano, E., Radiation-induced emesis: A problem with many open questions (2001) Tumori, 87 (4), pp. 213-218", "listPosition" : 2, "published" : false, "snippet" : true }, { "otype" : "Reference", "mtid" : 29489047, "link" : "/api/reference/29489047", "label" : "3. Maranzano, E., De Angelis, V., Pergolizzi, S., A prospective observational trial on emesis in radiotherapy: Analysis of 1020 patients recruited in 45 Italian radiation oncology centres (2010) Radiother Oncol, 94 (1), pp. 36-41", "listPosition" : 3, "published" : false, "snippet" : true }, { "otype" : "Reference", "mtid" : 29489046, "link" : "/api/reference/29489046", "label" : "4. Feyer, P.C., Maranzano, E., Molassiotis, A., Radiotherapy-induced nausea and vomiting (RINV): MASCC/ESMO guideline for antiemetics in radiotherapy: Update 2009 (2011) Support Care Cancer, 19 (SUPPL.), pp. 1S5-1S14", "listPosition" : 4, "published" : false, "snippet" : true }, { "otype" : "Reference", "mtid" : 29489045, "link" : "/api/reference/29489045", "label" : "5. Dennis, K., Maranzano, E., De Angelis, C., Radiotherapy-induced nausea and vomiting (2011) Expert Rev Pharmacoecon Outcomes Res, 11 (6), pp. 685-692", "listPosition" : 5, "published" : false, "snippet" : true }, { "otype" : "Reference", "mtid" : 29489044, "link" : "/api/reference/29489044", "label" : "6. Danjoux, C.E., Rider, W.D., Fitzpatrick, P.J., The acute radiation syndrome. A memorial to William Michael Court-Brown (1979) Clin Radiol, 30 (5), pp. 581-584", "listPosition" : 6, "published" : false, "snippet" : true }, { "otype" : "Reference", "mtid" : 29489043, "link" : "/api/reference/29489043", "label" : "7. Hird, A., Chow, E., Zhang, L., Determining the incidence of pain flare following palliative radiotherapy for symptomatic bone metastases: Results from three Canadian cancer centers (2009) Int J Radiat Oncol Biol Phys, 75 (1), pp. 193-197", "listPosition" : 7, "published" : false, "snippet" : true }, { "otype" : "Reference", "mtid" : 29489042, "link" : "/api/reference/29489042", "label" : "8. de Klerk, J.M., van het Schip, A.D., Zonnenberg, B.A., Phase 1 study of rhenium-186-HEDP in patients with bone metastases originating from breast cancer (1996) J Nucl Med, 37 (2), pp. 244-249", "listPosition" : 8, "published" : false, "snippet" : true }, { "otype" : "Reference", "mtid" : 29489041, "link" : "/api/reference/29489041", "label" : "9. Roka, R., Sera, T., Pajor, L., Clinical experience with rhenium-188 HEDP therapy for metastatic bone pain (2000) Orv Hetil, 141 (19), pp. 1019-1023", "listPosition" : 9, "published" : false, "snippet" : true }, { "otype" : "Reference", "mtid" : 29489040, "link" : "/api/reference/29489040", "label" : "10. Kraeber-Bodere, F., Campion, L., Rousseau, C., Treatment of bone metastases of prostate cancer with strontium-89 chloride: Efficacy in relation to the degree of bone involvement (2000) Eur J Nucl Med, 27 (10), pp. 1487-1493", "listPosition" : 10, "published" : false, "snippet" : true }, { "otype" : "Reference", "mtid" : 29489039, "link" : "/api/reference/29489039", "label" : "11. Silberstein, E.B., Teletherapy and radiopharmaceutical therapy of painful bone metastases (2005) Semin Nucl Med, 35 (2), pp. 152-158", "listPosition" : 11, "published" : false, "snippet" : true }, { "otype" : "Reference", "mtid" : 29489038, "link" : "/api/reference/29489038", "label" : "12. Teske, K., Daut, R.L., Cleeland, C.S., Relationships between nurses' observations and patients' self-reports of pain (1983) Pain, 16 (3), pp. 289-296", "listPosition" : 12, "published" : false, "snippet" : true }, { "otype" : "Reference", "mtid" : 29489037, "link" : "/api/reference/29489037", "label" : "13. Pelger, R.C., Soerdjbalie-Maikoe, V., Hamdy, N.A., Strategies for management of prostate cancer-related bone pain (2001) Drugs Aging, 18 (12), pp. 899-911", "listPosition" : 13, "published" : false, "snippet" : true }, { "otype" : "Reference", "mtid" : 29489036, "link" : "/api/reference/29489036", "label" : "14. Berenson, J.R., Lichtenstein, A., Porter, L., Long-term pamidronate treatment of advanced multiple myeloma patients reduces skeletal events. Myeloma Aredia Study Group (1998) J Clin Oncol, 16 (2), pp. 593-602", "listPosition" : 14, "published" : false, "snippet" : true }, { "otype" : "Reference", "mtid" : 29489035, "link" : "/api/reference/29489035", "label" : "15. Zheng, M., Letter to the editor: Comment on 'morbidity measures in the presence of recurrent composite endpoints' (2005) Pharm Stat 2003, 2 (1), pp. 39-49. , Scott M, M. ocks J, Givens S, et al", "listPosition" : 15, "published" : false, "snippet" : true }, { "otype" : "Reference", "mtid" : 29489034, "link" : "/api/reference/29489034", "label" : "16. Hortobagyi, G.N., Theriault, R.L., Porter, L., Efficacy of pamidronate in reducing skeletal complications in patients with breast cancer and lytic bone metastases. Protocol 19 Aredia Breast Cancer Study Group (1996) N Engl J Med, 335 (24), pp. 1785-1791", "listPosition" : 16, "published" : false, "snippet" : true }, { "otype" : "Reference", "mtid" : 29489033, "link" : "/api/reference/29489033", "label" : "17. Dearnaley, D.P., Mason, M.D., Parmar, M.K., Adjuvant therapy with oral sodium clodronate in locally advanced and metastatic prostate cancer: Long-term overall survival results from the MRC PR04 and PR05 randomised controlled trials (2009) Lancet Oncol, 10 (9), pp. 872-876", "listPosition" : 17, "published" : false, "snippet" : true }, { "otype" : "Reference", "mtid" : 29489032, "link" : "/api/reference/29489032", "label" : "18. Kristensen, B., Ejlertsen, B., Groenvold, M., Oral clodronate in breast cancer patients with bone metastases: A randomized study (1999) J Intern Med, 246 (1), pp. 67-74", "listPosition" : 18, "published" : false, "snippet" : true }, { "otype" : "Reference", "mtid" : 29489031, "link" : "/api/reference/29489031", "label" : "19. Spitzer, W.O., Dobson, A.J., Hall, J., Measuring the quality of life of cancer patients: A concise QL-index for use by physicians (1981) J Chronic Dis, 34 (12), pp. 585-597", "listPosition" : 19, "published" : false, "snippet" : true }, { "otype" : "Reference", "mtid" : 29489030, "link" : "/api/reference/29489030", "label" : "20. Matza, L.S., Fallowfield, L.J., Chung, K.C., Patient-reported outcome instruments used to assess pain and functioning in studies of bisphosphonate treatment for bone metastases (2012) Support Care Cancer, 20 (4), pp. 657-677", "listPosition" : 20, "published" : false, "snippet" : true }, { "otype" : "Reference", "mtid" : 29489029, "link" : "/api/reference/29489029", "label" : "21. Groff, L., Zecca, E., De Conno, F., The role of disodium pamidronate in the management of bone pain due to malignancy (2001) Palliat Med, 15 (4), pp. 297-307", "listPosition" : 21, "published" : false, "snippet" : true }, { "otype" : "Reference", "mtid" : 29489028, "link" : "/api/reference/29489028", "label" : "22. Body, J.J., Diel, I.J., Bell, R., Oral ibandronate improves bone pain and preserves quality of life in patients with skeletal metastases due to breast cancer (2004) Pain, 111 (3), pp. 306-312", "listPosition" : 22, "published" : false, "snippet" : true }, { "otype" : "Reference", "mtid" : 29489027, "link" : "/api/reference/29489027", "label" : "23. Diel, I.J., Body, J.J., Lichinitser, M.R., Improved quality of life after long-term treatment with the bisphosphonate ibandronate in patients with metastatic bone disease due to breast cancer (2004) Eur J Cancer, 40 (11), pp. 1704-1712", "listPosition" : 23, "published" : false, "snippet" : true }, { "otype" : "Reference", "mtid" : 29489026, "link" : "/api/reference/29489026", "label" : "24. Fizazi, K., Carducci, M., Smith, M., Denosumab versus zoledronic acid for treatment of bone metastases in men with castration-resistant prostate cancer: A randomised, doubleblind study (2011) Lancet, 377 (9768), pp. 813-822", "listPosition" : 24, "published" : false, "snippet" : true }, { "otype" : "Reference", "mtid" : 29489025, "link" : "/api/reference/29489025", "label" : "25. Moecks, J., Koch, G.G., Scott, M., Measures of morbidity in clinical studies with recurrent skeletal complications (2004) J Biopharm Stat, 14 (2), pp. 415-437", "listPosition" : 25, "published" : false, "snippet" : true }, { "otype" : "Reference", "mtid" : 29489024, "link" : "/api/reference/29489024", "label" : "26. Scott, M., Mocks, J., Givens, S., Morbidity measures in the presence of recurrent composite endpoints (2003) Pharm Stat, 2, pp. 39-49", "listPosition" : 26, "published" : false, "snippet" : true }, { "otype" : "Reference", "mtid" : 29489023, "link" : "/api/reference/29489023", "label" : "27. Stopeck, A.T., Lipton, A., Body, J.J., Denosumab compared with zoledronic acid for the treatment of bone metastases in patients with advanced breast cancer: A randomized, double-blind study (2010) J Clin Oncol, 28 (35), pp. 5132-5139", "listPosition" : 27, "published" : false, "snippet" : true }, { "otype" : "Reference", "mtid" : 29489022, "link" : "/api/reference/29489022", "label" : "28. Saad, F., Clinical benefit of zoledronic acid for the prevention of skeletal complications in advanced prostate cancer (2005) Clin Prostate Cancer, 4 (1), pp. 31-37", "listPosition" : 28, "published" : false, "snippet" : true }, { "otype" : "Reference", "mtid" : 29489021, "link" : "/api/reference/29489021", "label" : "29. Rosen, L.S., Gordon, D.H., Dugan Jr., W., Zoledronic acid is superior to pamidronate for the treatment of bone metastases in breast carcinoma patients with at least one osteolytic lesion (2004) Cancer, 100 (1), pp. 36-43", "listPosition" : 29, "published" : false, "snippet" : true }, { "otype" : "Reference", "mtid" : 29489020, "link" : "/api/reference/29489020", "label" : "30. Rosen, L.S., Gordon, D., Tchekmedyian, S., Zoledronic acid versus placebo in the treatment of skeletal metastases in patients with lung cancer and other solid tumors: A phase III, double-blind, randomized trial-the Zoledronic Acid Lung Cancer and Other Solid Tumors Study Group (2003) J Clin Oncol, 21 (16), pp. 3150-3157", "listPosition" : 30, "published" : false, "snippet" : true }, { "otype" : "Reference", "mtid" : 29489019, "link" : "/api/reference/29489019", "label" : "31. Lipton, A., Zheng, M., Seaman, J., Zoledronic acid delays the onset of skeletal-related events and progression of skeletal disease in patients with advanced renal cell carcinoma (2003) Cancer, 98 (5), pp. 962-969", "listPosition" : 31, "published" : false, "snippet" : true }, { "otype" : "Reference", "mtid" : 29489018, "link" : "/api/reference/29489018", "label" : "32. Kohno, N., Aogi, K., Minami, H., Zoledronic acid significantly reduces skeletal complications compared with placebo in Japanese women with bone metastases from breast cancer: A randomized, placebo-controlled trial (2005) J Clin Oncol, 23 (15), pp. 3314-3321", "listPosition" : 32, "published" : false, "snippet" : true }, { "otype" : "Reference", "mtid" : 29489017, "link" : "/api/reference/29489017", "label" : "33. Body, J.J., Diel, I.J., Lichinitser, M.R., Intravenous ibandronate reduces the incidence of skeletal complications in patients with breast cancer and bone metastases (2003) Ann Oncol, 14 (9), pp. 1399-1405", "listPosition" : 33, "published" : false, "snippet" : true }, { "otype" : "Reference", "mtid" : 29489016, "link" : "/api/reference/29489016", "label" : "34. Rosen, L.S., Gordon, D., Kaminski, M., Zoledronic acid versus pamidronate in the treatment of skeletal metastases in patients with breast cancer or osteolytic lesions of multiple myeloma: A phase III, double-blind, comparative trial (2001) Cancer J, 7 (5), pp. 377-387", "listPosition" : 34, "published" : false, "snippet" : true }, { "otype" : "Reference", "mtid" : 29489015, "link" : "/api/reference/29489015", "label" : "35. Clemons, M., Dranitsaris, G., Cole, D., Too much, too little, too late to start again? Assessing the efficacy of bisphosphonates in patients with bone metastases from breast cancer (2006) Oncologist, 11 (3), pp. 227-233", "listPosition" : 35, "published" : false, "snippet" : true }, { "otype" : "Reference", "mtid" : 29489014, "link" : "/api/reference/29489014", "label" : "36. Zaghloul, M.S., Boutrus, R., El-Hossieny, H., A prospective, randomized, placebocontrolled trial of zoledronic acid in bony metastatic bladder cancer (2010) Int J Clin Oncol, 15 (4), pp. 382-389", "listPosition" : 36, "published" : false, "snippet" : true }, { "otype" : "Reference", "mtid" : 29489013, "link" : "/api/reference/29489013", "label" : "37. Tripathy, D., Lichinitzer, M., Lazarev, A., Oral ibandronate for the treatment of metastatic bone disease in breast cancer: Efficacy and safety results from a randomized, doubleblind, placebo-controlled trial (2004) Ann Oncol, 15 (5), pp. 743-750", "listPosition" : 37, "published" : false, "snippet" : true }, { "otype" : "Reference", "mtid" : 29489012, "link" : "/api/reference/29489012", "label" : "38. Theriault, R.L., Lipton, A., Hortobagyi, G.N., Pamidronate reduces skeletal morbidity in women with advanced breast cancer and lytic bone lesions: A randomized, placebo-controlled trial. Protocol 18 Aredia Breast Cancer Study Group (1999) J Clin Oncol, 17 (3), pp. 846-854", "listPosition" : 38, "published" : false, "snippet" : true }, { "otype" : "Reference", "mtid" : 29489011, "link" : "/api/reference/29489011", "label" : "39. Johnson, J.R., Williams, G., Pazdur, R., End points and United States food and drug administration approval of oncology drugs (2003) J Clin Oncol, 21 (7), pp. 1404-1411", "listPosition" : 39, "published" : false, "snippet" : true }, { "otype" : "Reference", "mtid" : 29489010, "link" : "/api/reference/29489010", "label" : "40. Major, P., Cook, R., Clinical endpoints for assessing bisphosphonate efficacy in the prevention of skeletal complications of bone metastases (2004) Eur Urol Suppl, 3 (5), pp. 334-339", "listPosition" : 40, "published" : false, "snippet" : true }, { "otype" : "Reference", "mtid" : 29489009, "link" : "/api/reference/29489009", "label" : "41. Saad, F., Gleason, D.M., Murray, R., A randomized, placebo-controlled trial of zoledronic acid in patients with hormone-refractory metastatic prostate carcinoma (2002) J Natl Cancer Inst, 94 (19), pp. 1458-1468", "listPosition" : 41, "published" : false, "snippet" : true }, { "otype" : "Reference", "mtid" : 29489008, "link" : "/api/reference/29489008", "label" : "42. Paterson, A.H., Powles, T.J., Kanis, J.A., Double-blind controlled trial of oral clodronate in patients with bone metastases from breast cancer (1993) J Clin Oncol, 11 (1), pp. 59-65", "listPosition" : 42, "published" : false, "snippet" : true }, { "otype" : "Reference", "mtid" : 29489007, "link" : "/api/reference/29489007", "label" : "43. Saad, F., Chen, Y.M., Gleason, D.M., Continuing benefit of zoledronic acid in preventing skeletal complications in patients with bone metastases (2007) Clin Genitourin Cancer, 5 (6), pp. 390-396", "listPosition" : 43, "published" : false, "snippet" : true }, { "otype" : "Reference", "mtid" : 29489006, "link" : "/api/reference/29489006", "label" : "44. Henry, D.H., Costa, L., Goldwasser, F., Randomized, double-blind study of denosumab versus zoledronic acid in the treatment of bone metastases in patients with advanced cancer (excluding breast and prostate cancer) or multiple myeloma (2011) J Clin Oncol, 29 (9), pp. 1125-1132", "listPosition" : 44, "published" : false, "snippet" : true }, { "otype" : "Reference", "mtid" : 29489005, "link" : "/api/reference/29489005", "label" : "45. Major, P.P., Cook, R., Efficacy of bisphosphonates in the management of skeletal complications of bone metastases and selection of clinical endpoints (2002) Am J Clin Oncol, 25 (6 SUPPL. 1), pp. S10-S18", "listPosition" : 45, "published" : false, "snippet" : true }, { "otype" : "Reference", "mtid" : 29489004, "link" : "/api/reference/29489004", "label" : "46. Farrar, J.T., Berlin, J.A., Strom, B.L., Clinically important changes in acute pain outcome measures: A validation study (2003) J Pain Symptom Manage, 25 (5), pp. 406-411", "listPosition" : 46, "published" : false, "snippet" : true }, { "otype" : "Reference", "mtid" : 29489003, "link" : "/api/reference/29489003", "label" : "47. Chow, E., Chiu, H., Doyle, M., Patient expectation of the partial response and response shift in pain score (2007) Support Cancer Ther, 4 (2), pp. 110-118", "listPosition" : 47, "published" : false, "snippet" : true }, { "otype" : "Reference", "mtid" : 29489002, "link" : "/api/reference/29489002", "label" : "48. Lenert, L.A., Treadwell, J.R., Schwartz, C.E., Associations between health status and utilities implications for policy (1999) Med Care, 37 (5), pp. 479-489", "listPosition" : 48, "published" : false, "snippet" : true }, { "otype" : "Reference", "mtid" : 29489001, "link" : "/api/reference/29489001", "label" : "49. Steenland, E., Leer, J.W., van Houwelingen, H., The effect of a single fraction compared to multiple fractions on painful bone metastases: A global analysis of the Dutch Bone Metastasis Study (1999) Radiother Oncol, 52 (2), pp. 101-109", "listPosition" : 49, "published" : false, "snippet" : true }, { "otype" : "Reference", "mtid" : 29489000, "link" : "/api/reference/29489000", "label" : "50. Hartsell, W.F., Scott, C.B., Bruner, D.W., Randomized trial of short-versus long-course radiotherapy for palliation of painful bone metastases (2005) J Natl Cancer Inst, 97 (11), pp. 798-804", "listPosition" : 50, "published" : false, "snippet" : true }, { "otype" : "Reference", "mtid" : 29488999, "link" : "/api/reference/29488999", "label" : "51. Chow, E., Hird, A., Wong, R., Validation of meaningful change in pain scores in the treatment of bone metastases (2010) Pain and quality of life, , In: Chow E, Merrick J (eds), Nova Science Publishers, New York", "listPosition" : 51, "published" : false, "snippet" : true }, { "otype" : "Reference", "mtid" : 29488998, "link" : "/api/reference/29488998", "label" : "52. Chow, E., Ling, A., Davis, L., Pain flare following external beam radiotherapy and meaningful change in pain scores in the treatment of bone metastases (2005) Radiother Oncol, 75 (1), pp. 64-69", "listPosition" : 52, "published" : false, "snippet" : true }, { "otype" : "Reference", "mtid" : 29488997, "link" : "/api/reference/29488997", "label" : "53. Sprangers, M.A., Aaronson, N.K., The role of health care providers and significant others in evaluating the quality of life of patients with chronic disease: A review (1992) J Clin Epidemiol, 45 (7), pp. 743-760", "listPosition" : 53, "published" : false, "snippet" : true }, { "otype" : "Reference", "mtid" : 29488996, "link" : "/api/reference/29488996", "label" : "54. Sneeuw, K.C., Aaronson, N.K., Sprangers, M.A., Value of caregiver ratings in evaluating the quality of life of patients with cancer (1997) J Clin Oncol, 15 (3), pp. 1206-1217", "listPosition" : 54, "published" : false, "snippet" : true }, { "otype" : "Reference", "mtid" : 29488995, "link" : "/api/reference/29488995", "label" : "55. Slevin, M.L., Plant, H., Lynch, D., Who should measure quality of life, the doctor or the patient? (1988) Br J Cancer, 57 (1), pp. 109-112", "listPosition" : 55, "published" : false, "snippet" : true }, { "otype" : "Reference", "mtid" : 29488994, "link" : "/api/reference/29488994", "label" : "56. Nekolaichuk, C.L., Bruera, E., Spachynski, K., A comparison of patient and proxy symptom assessments in advanced cancer patients (1999) Palliat Med, 13 (4), pp. 311-323", "listPosition" : 56, "published" : false, "snippet" : true }, { "otype" : "Reference", "mtid" : 29488993, "link" : "/api/reference/29488993", "label" : "57. Higginson, I.J., Can professionals improve their assessments? (1998) J Pain Symptom Manage, 15 (3), pp. 149-150", "listPosition" : 57, "published" : false, "snippet" : true }, { "otype" : "Reference", "mtid" : 29488992, "link" : "/api/reference/29488992", "label" : "58. Higginson, I.J., McCarthy, M., Validity of the support team assessment schedule: Do staffs' ratings reflect those made by patients or their families? (1993) Palliat Med, 7 (3), pp. 219-228", "listPosition" : 58, "published" : false, "snippet" : true }, { "otype" : "Reference", "mtid" : 29488991, "link" : "/api/reference/29488991", "label" : "59. Grossman, S.A., Sheidler, V.R., Swedeen, K., Correlation of patient and caregiver ratings of cancer pain (1991) J Pain Symptom Manage, 6 (2), pp. 53-57", "listPosition" : 59, "published" : false, "snippet" : true }, { "otype" : "Reference", "mtid" : 29488990, "link" : "/api/reference/29488990", "label" : "60. Brunelli, C., Costantini, M., Di Giulio, P., Quality-of-life evaluation: When do terminal cancer patients and health-care providers agree? (1998) J Pain Symptom Manage, 15 (3), pp. 151-158", "listPosition" : 60, "published" : false, "snippet" : true }, { "otype" : "Reference", "mtid" : 29488989, "link" : "/api/reference/29488989", "label" : "61. Li, K.K., Hadi, S., Kirou-Mauro, A., When should we define the response rates in the treatment of bone metastases by palliative radiotherapy? (2008) Clin Oncol (R Coll Radiol), 20 (1), pp. 83-89", "listPosition" : 61, "published" : false, "snippet" : true }, { "otype" : "Reference", "mtid" : 29488988, "link" : "/api/reference/29488988", "label" : "62. Li, K.K., Harris, K., Hadi, S., What should be the optimal cut points for mild, moderate, and severe pain? (2007) J Palliat Med, 10 (6), pp. 1338-1346", "listPosition" : 62, "published" : false, "snippet" : true }, { "otype" : "Reference", "mtid" : 29488987, "link" : "/api/reference/29488987", "label" : "63. (2008) NCCN clinical practice guidelines in oncology: Adult cancer pain V, , http://www.nccn.org/professionals/physician_gls/PDF/pain.pdf, National Comprehensive Cancer Network, Accessed 15 Aug 2008, 1. 2006", "listPosition" : 63, "published" : false, "snippet" : true }, { "otype" : "Reference", "mtid" : 29488986, "link" : "/api/reference/29488986", "label" : "64. Gordon, D.B., Dahl, J.L., Miaskowski, C., American pain society recommendations for improving the quality of acute and cancer pain management: American Pain Society Quality of Care Task Force (2005) Arch Intern Med, 165 (14), pp. 1574-1580", "listPosition" : 64, "published" : false, "snippet" : true }, { "otype" : "Reference", "mtid" : 29488985, "link" : "/api/reference/29488985", "label" : "65. Clark, P., Lavielle, P., Martinez, H., Learning from pain scales: Patient perspective (2003) J Rheumatol, 30 (7), pp. 1584-1588", "listPosition" : 65, "published" : false, "snippet" : true }, { "otype" : "Reference", "mtid" : 29488984, "link" : "/api/reference/29488984", "label" : "66. Anderson, K.O., Role of cutpoints: Why grade pain intensity? (2005) Pain, 113 (1-2), pp. 5-6", "listPosition" : 66, "published" : false, "snippet" : true }, { "otype" : "Reference", "mtid" : 29488983, "link" : "/api/reference/29488983", "label" : "67. Serlin, R.C., Mendoza, T.R., Nakamura, Y., When is cancer pain mild, moderate or severe? Grading pain severity by its interference with function (1995) Pain, 61 (2), pp. 277-284", "listPosition" : 67, "published" : false, "snippet" : true }, { "otype" : "Reference", "mtid" : 29488982, "link" : "/api/reference/29488982", "label" : "68. McMillan, S.C., Tittle, M., Hagan, S., Management of pain and pain-related symptoms in hospitalized veterans with cancer (2000) Cancer Nurs, 23 (5), pp. 327-336", "listPosition" : 68, "published" : false, "snippet" : true }, { "otype" : "Reference", "mtid" : 29488981, "link" : "/api/reference/29488981", "label" : "69. Wu, J.S., Monk, G., Clark, T., Palliative radiotherapy improves pain and reduces functional interference in patients with painful bone metastases: A quality assurance study (2006) Clin Oncol (R Coll Radiol), 18 (7), pp. 539-544", "listPosition" : 69, "published" : false, "snippet" : true }, { "otype" : "Reference", "mtid" : 29488980, "link" : "/api/reference/29488980", "label" : "70. Ger, L.P., Ho, S.T., Sun, W.Z., Validation of the brief pain inventory in a Taiwanese population (1999) J Pain Symptom Manage, 18 (5), pp. 316-322", "listPosition" : 70, "published" : false, "snippet" : true }, { "otype" : "Reference", "mtid" : 29488979, "link" : "/api/reference/29488979", "label" : "71. Cleeland, C.S., Ryan, K.M., Pain assessment: Global use of the brief pain inventory (1994) Ann Acad Med Singapore, 23 (2), pp. 129-138", "listPosition" : 71, "published" : false, "snippet" : true }, { "otype" : "Reference", "mtid" : 29488978, "link" : "/api/reference/29488978", "label" : "72. Harris, K., Li, K., Flynn, C., Worst, average or current pain in the brief pain inventory: Which should be used to calculate the response to palliative radiotherapy in patients with bone metastases? (2007) Clin Oncol (R Coll Radiol), 19 (7), pp. 523-527", "listPosition" : 72, "published" : false, "snippet" : true }, { "otype" : "Reference", "mtid" : 29488977, "link" : "/api/reference/29488977", "label" : "73. Miaskowski, C., The next step to improving cancer pain management (2005) Pain Manag Nurs, 6 (1), pp. 1-2", "listPosition" : 73, "published" : false, "snippet" : true }, { "otype" : "Reference", "mtid" : 29488976, "link" : "/api/reference/29488976", "label" : "74. (1986) Expert Advisory Committee on the Management of Severe Chronic Pain in Cancer Patients (Canada), , Begin M, Canada. Health, Welfare Canada. Cancer Pain: A Monograph on the Management of Cancer Pain: a Report of the Expert Advisory Committee on the Management of Severe Chronic Pain in Cancer Patients to the Honourable Monique Begin.: Health and Welfare Canada", "listPosition" : 74, "published" : false, "snippet" : true }, { "otype" : "Reference", "mtid" : 29488975, "link" : "/api/reference/29488975", "label" : "75. Vigano, A., Dorgan, M., Buckingham, J., Survival prediction in terminal cancer patients: A systematic review of the medical literature (2000) Palliat Med, 14 (5), pp. 363-374", "listPosition" : 75, "published" : false, "snippet" : true }, { "otype" : "Reference", "mtid" : 29488974, "link" : "/api/reference/29488974", "label" : "76. Chow, E., Harth, T., Hruby, G., How accurate are physicians' clinical predictions of survival and the available prognostic tools in estimating survival times in terminally ill cancer patients? A systematic review (2001) Clin Oncol (R Coll Radiol), 13 (3), pp. 209-218", "listPosition" : 76, "published" : false, "snippet" : true }, { "otype" : "Reference", "mtid" : 29488973, "link" : "/api/reference/29488973", "label" : "77. Yates, J.W., Chalmer, B., McKegney, F.P., Evaluation of patients with advanced cancer using the Karnofsky performance status (1980) Cancer, 45 (8), pp. 2220-2224", "listPosition" : 77, "published" : false, "snippet" : true }, { "otype" : "Reference", "mtid" : 29488972, "link" : "/api/reference/29488972", "label" : "78. Mor, V., Laliberte, L., Morris, J.N., The Karnofsky performance status scale. An examination of its reliability and validity in a research setting (1984) Cancer, 53 (9), pp. 2002-2007", "listPosition" : 78, "published" : false, "snippet" : true }, { "otype" : "Reference", "mtid" : 29488971, "link" : "/api/reference/29488971", "label" : "79. Chow, E., Wu, J.S., Hoskin, P., International consensus on palliative radiotherapy endpoints for future clinical trials in bone metastases (2002) Radiother Oncol, 64 (3), pp. 275-280", "listPosition" : 79, "published" : false, "snippet" : true }, { "otype" : "Reference", "mtid" : 29488970, "link" : "/api/reference/29488970", "label" : "80. Chow, E., Hoskin, P., Mitera, G., Update of the international consensus on palliative radiotherapy endpoints for future clinical trials in bone metastases (2012) Int J Radiat Oncol Biol Phys, 82 (5), pp. 1730-1737", "listPosition" : 80, "published" : false, "snippet" : true }, { "otype" : "Reference", "mtid" : 29488969, "link" : "/api/reference/29488969", "label" : "81. Nielsen, O.S., Bentzen, S.M., Sandberg, E., Randomized trial of single dose versus fractionated palliative radiotherapy of bone metastases (1998) Radiother Oncol, 47 (3), pp. 233-240", "listPosition" : 81, "published" : false, "snippet" : true }, { "otype" : "Reference", "mtid" : 29488968, "link" : "/api/reference/29488968", "label" : "82. Blitzer, P.H., Reanalysis of the RTOG study of the palliation of symptomatic osseous metastasis (1985) Cancer, 55 (7), pp. 1468-1472", "listPosition" : 82, "published" : false, "snippet" : true }, { "otype" : "Reference", "mtid" : 29488967, "link" : "/api/reference/29488967", "label" : "83. Tong, D., Gillick, L., Hendrickson, F.R., The palliation of symptomatic osseous metastases: Final results of the study by the Radiation Therapy Oncology Group (1982) Cancer, 50 (5), pp. 893-899", "listPosition" : 83, "published" : false, "snippet" : true }, { "otype" : "Reference", "mtid" : 29488966, "link" : "/api/reference/29488966", "label" : "84. Kirkbride, P., Warde, P., Panzarella, T., A randomised trial comparing the efficacy and safety of single fraction radiation therapy plus Ondansetron with fractionated therapy in the palliation of skeletal metastases [Abstract] (2000) Int J Rad Oncol Biol Phys, 48 (3 SUPPL.), p. 185", "listPosition" : 84, "published" : false, "snippet" : true }, { "otype" : "Reference", "mtid" : 29488965, "link" : "/api/reference/29488965", "label" : "85. Wu, J.S., Bezjak, A., Chow, E., Primary treatment endpoint following palliative radiotherapy for painful bone metastases: Need for a consensus definition? (2002) Clin Oncol (R Coll Radiol), 14 (1), pp. 70-77", "listPosition" : 85, "published" : false, "snippet" : true }, { "otype" : "Reference", "mtid" : 29488964, "link" : "/api/reference/29488964", "label" : "86. Gupta, T., Sarin, R., Palliative radiation therapy for painful vertebral metastases: A practice survey (2004) Cancer, 101 (12), pp. 2892-2896", "listPosition" : 86, "published" : false, "snippet" : true }, { "otype" : "Reference", "mtid" : 29488963, "link" : "/api/reference/29488963", "label" : "87. Moller, T.R., Brorsson, B., Ceberg, J., A prospective survey of radiotherapy practice 2001 in Sweden (2003) Acta Oncol, 42 (5-6), pp. 387-410", "listPosition" : 87, "published" : false, "snippet" : true }, { "otype" : "Reference", "mtid" : 29488962, "link" : "/api/reference/29488962", "label" : "88. Roos, D.E., Continuing reluctance to use single fractions of radiotherapy for metastatic bone pain: An Australian and New Zealand practice survey and literature review (2000) Radiother Oncol, 56 (3), pp. 315-322", "listPosition" : 88, "published" : false, "snippet" : true }, { "otype" : "Reference", "mtid" : 29488961, "link" : "/api/reference/29488961", "label" : "89. Lievens, Y., Kesteloot, K., Rijnders, A., Differences in palliative radiotherapy for bone metastases within Western European countries (2000) Radiother Oncol, 56 (3), pp. 297-303", "listPosition" : 89, "published" : false, "snippet" : true }, { "otype" : "Reference", "mtid" : 29488960, "link" : "/api/reference/29488960", "label" : "90. Chow, E., Danjoux, C., Wong, R., Palliation of bone metastases: A survey of patterns of practice among Canadian radiation oncologists (2000) Radiother Oncol, 56 (3), pp. 305-314", "listPosition" : 90, "published" : false, "snippet" : true }, { "otype" : "Reference", "mtid" : 29488959, "link" : "/api/reference/29488959", "label" : "91. Ben-Josef, E., Shamsa, F., Williams, A.O., Radiotherapeutic management of osseous metastases: A survey of current patterns of care (1998) Int J Radiat Oncol Biol Phys, 40 (4), pp. 915-921", "listPosition" : 91, "published" : false, "snippet" : true }, { "otype" : "Reference", "mtid" : 29488958, "link" : "/api/reference/29488958", "label" : "92. Stevens, G., Firth, I., Patterns of fractionation for palliation of bone metastases (1995) Australas Radiol, 39 (1), pp. 31-35", "listPosition" : 92, "published" : false, "snippet" : true }, { "otype" : "Reference", "mtid" : 29488957, "link" : "/api/reference/29488957", "label" : "93. Duncan, G., Duncan, W., Maher, E.J., Patterns of palliative radiotherapy in Canada (1993) Clin Oncol (R Coll Radiol), 5 (2), pp. 92-97", "listPosition" : 93, "published" : false, "snippet" : true }, { "otype" : "Reference", "mtid" : 29488956, "link" : "/api/reference/29488956", "label" : "94. Maher, E.J., Coia, L., Duncan, G., Treatment strategies in advanced and metastatic cancer: Differences in attitude between the USA, Canada and Europe (1992) Int J Radiat Oncol Biol Phys, 23 (1), pp. 239-244", "listPosition" : 94, "published" : false, "snippet" : true }, { "otype" : "Reference", "mtid" : 29488955, "link" : "/api/reference/29488955", "label" : "95. Lawton, P.A., Maher, E.J., Treatment strategies for advanced and metastatic cancer in Europe (1991) Radiother Oncol, 22 (1), pp. 1-6", "listPosition" : 95, "published" : false, "snippet" : true }, { "otype" : "Reference", "mtid" : 29488954, "link" : "/api/reference/29488954", "label" : "96. Crellin, A.M., Marks, A., Maher, E.J., Why don't British radiotherapists give single fractions of radiotherapy for bone metastases? (1989) Clin Oncol (R Coll Radiol), 1 (2), pp. 63-66", "listPosition" : 96, "published" : false, "snippet" : true }, { "otype" : "Reference", "mtid" : 29488953, "link" : "/api/reference/29488953", "label" : "97. Priestman, T.J., Dunn, J., Brada, M., Final results of the Royal College of Radiologists' trial comparing two different radiotherapy schedules in the treatment of cerebral metastases (1996) Clin Oncol (R Coll Radiol), 8 (5), pp. 308-315", "listPosition" : 97, "published" : false, "snippet" : true }, { "otype" : "Reference", "mtid" : 29488952, "link" : "/api/reference/29488952", "label" : "98. Coia, L.R., Hanks, G.E., Martz, K., Practice patterns of palliative care for the United States 1984-1985 (1988) Int J Radiat Oncol Biol Phys, 14 (6), pp. 1261-1269", "listPosition" : 98, "published" : false, "snippet" : true }, { "otype" : "Reference", "mtid" : 29488951, "link" : "/api/reference/29488951", "label" : "99. Wu, J.S., Wong, R., Johnston, M., Meta-analysis of dose-fractionation radiotherapy trials for the palliation of painful bone metastases (2003) Int J Radiat Oncol Biol Phys, 55 (3), pp. 594-605", "listPosition" : 99, "published" : false, "snippet" : true }, { "otype" : "Reference", "mtid" : 29488950, "link" : "/api/reference/29488950", "label" : "100. Sze, W.M., Shelley, M.D., Held, I., Palliation of metastatic bone pain: Single fraction versus multifraction radiotherapy-a systematic review of randomised trials (2003) Clin Oncol (R Coll Radiol), 15 (6), pp. 345-352", "listPosition" : 100, "published" : false, "snippet" : true }, { "otype" : "Reference", "mtid" : 29488949, "link" : "/api/reference/29488949", "label" : "101. Chow, E., Harris, K., Fan, G., Palliative radiotherapy trials for bone metastases: A systematic review (2007) J Clin Oncol, 25 (11), pp. 1423-1436", "listPosition" : 101, "published" : false, "snippet" : true }, { "otype" : "Reference", "mtid" : 29488948, "link" : "/api/reference/29488948", "label" : "102. Brown, J.E., Coleman, R.E., The present and future role of bisphosphonates in the management of patients with breast cancer (2002) Breast Cancer Res, 4 (1), pp. 24-29", "listPosition" : 102, "published" : false, "snippet" : true }, { "otype" : "Reference", "mtid" : 29488947, "link" : "/api/reference/29488947", "label" : "103. Costa, L., Major, P.P., Effect of bisphosphonates on pain and quality of life in patients with bone metastases (2009) Nat Clin Pract Oncol, 6 (3), pp. 163-174", "listPosition" : 103, "published" : false, "snippet" : true }, { "otype" : "Reference", "mtid" : 29488946, "link" : "/api/reference/29488946", "label" : "104. Lipton, A., Theriault, R.L., Hortobagyi, G.N., Pamidronate prevents skeletal complications and is effective palliative treatment in women with breast carcinoma and osteolytic bone metastases: Long term follow-up of two randomized, placebo-controlled trials (2000) Cancer, 88 (5), pp. 1082-1090", "listPosition" : 104, "published" : false, "snippet" : true } ], "hasCitationDuplums" : false, "userChangeableUntil" : "2022-03-31T17:54:24.643+0000", "directInstitutesForSort" : "", "ownerAuthorCount" : 6, "ownerInstituteCount" : 13, "directInstituteCount" : 0, "authorCount" : 4, "contributorCount" : 0, "book" : { "otype" : "Book", "mtid" : 31403560, "link" : "/api/publication/31403560", "label" : "Kardamakis D.. Cancer Metastasis - Biology and Treatment. (2014) ISBN:9789400775688", "core" : false, "citation" : false, "publicationPending" : false, "type" : { "otype" : "PublicationType", "mtid" : 23, "link" : "/api/publicationtype/23", "label" : "Könyv", "code" : 23, "otypeName" : "Book", "listPosition" : 3, "published" : true, "oldId" : 23, "snippet" : true }, "category" : { "otype" : "Category", "mtid" : 1, "link" : "/api/category/1", "label" : "Tudományos", "published" : true, "oldId" : 1, "snippet" : true }, "languages" : [ { "otype" : "Language", "mtid" : 10002, "link" : "/api/language/10002", "label" : "Angol", "name" : "Angol", "nameEng" : "English", "published" : true, "oldId" : 2, "snippet" : true } ], "title" : "Cancer Metastasis - Biology and Treatment", "identifiers" : [ { "otype" : "PublicationIdentifier", "mtid" : 17116625, "link" : "/api/publicationidentifier/17116625", "label" : "ISBN: 9789400775688", "source" : { "otype" : "PlainSource", "mtid" : 122, "link" : "/api/publicationsource/122", "label" : "ISBN", "type" : { "otype" : "PublicationSourceType", "mtid" : 10002, "link" : "/api/publicationsourcetype/10002", "label" : "Egyéb", "mayHaveOa" : false, "published" : true, "snippet" : true }, "name" : "ISBN", "nameEng" : "ISBN", "linkPattern" : "https://www.worldcat.org/search?q=isbn%3A@@@", "publiclyVisible" : true, "published" : true, "oldId" : 122, "snippet" : true }, "idValue" : "9789400775688", "realUrl" : "https://www.worldcat.org/search?q=isbn%3A9789400775688", "published" : false, "snippet" : true } ], "publishedAt" : [ ], "publishedYear" : 2014, "foreignLanguage" : true, "fullPublication" : false, "published" : true, "snippet" : true }, "hasQualityFactor" : false, "link" : "/api/publication/32769128", "label" : "Poon M. et al. Outcome Measures in Bone Metastases Clinical Trials. (2014) Megjelent: Cancer Metastasis - Biology and Treatment pp. 419-439", "template" : "