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cholinesterase in scopolamine model rat brain (2000) Pharmacology and Clinics of Chinese Materia Medica, 16, pp. 5-7; \n\nBurn, C.C., Peters, A., Day, M.J., Mason, G.J., Long-term effects of cage-cleaning frequency and bedding type on laboratory rat health, welfare, and handleability: A cross-laboratory study (2006) Laboratory Animals, 40 (4), pp. 353-370. , DOI 10.1258/002367706778476460; \n\n(2005) What Is An LD50 and LC50, Canada's National Occupational Health and Safety Resource, , http://www.ccohs.ca/oshanswers/chemicals/ld50.html, CCOHS: Canadian Centre for Occupational Health and Safety; \n\nDerelanko, M.J., (2008) The Toxicologist's Pocket Handbook, , second ed. Informa Healthcare UK; \n\nFirenzuoli, F., Gori, L., Herbal medicine today: Clinical and research issues (2007) Evidence Based Complement and Alternative Medicine, 4, pp. 37-40; \n\nHuang, Y.F., Bian, H.M., Gong, J.N., Liu, X.F., The effect of Kai-Xin-San on the content of SOD and MDA in four kinds of rat models (1999) Journal of Nanjing University TCM, 15, pp. 151-152; \n\nHou, L., Determination of ginsenoside Rg1 and Re in kaixinsan by RP-HPLC (2008) Acta Academiae Medicinae CPAF, 17, pp. 777-783; \n\nKennedy, D.O., Scholey, A.B., Ginseng: Potential for the enhancement of cognitive performance and mood (2003) Pharmacology Biochemistry and Behavior, 75 (3), pp. 687-700. , DOI 10.1016/S0091-3057(03)00126-6; \n\nKim, J.C., Kang, B.H., Shin, C.C., Kim, Y.B., Lee, H.S., Kim, C.Y., Han, J., Chung, M.K., Subchronic toxicity of plant sterol esters administered by gavage to Sprague-Dawley rat (2002) Food and Chemical Toxicology, 40, pp. 1569-1580; \n\nLahlou, S., Zafar, H.I., Badiaa, L., Acute and chronic toxicity of a lyophilized aqueous extract of Tanacetum vulgare leaves in rodents (2008) Journal of Ethnopharmacology, 117, pp. 221-227; \n\nLiu, J.Y., Xiao, S.Y., Shang, W.F., Xu, L.Z., Yang, S.L., A new minor triterpene saponin from kaixinsan prescription (2005) Journal of Asian Natural Product Research, 7, pp. 643-648; \n\nMolle, J., Limites de tolérance et toxicités de quelques amino acides (Forme L. et D) (1986) Amino-peptides-protéines, pp. 207-232. , In: Cahier N 4, Ed AEC; \n\nMook-Jung, I., Hong, H.-S., Boo, J.H., Lee, K.H., Yun, S.H., Cheong, M.Y., Joo, I., Jung, M.W., Ginsenoside Rb1 and Rg1 improve spatial learning and increase hippocampal synaptophysin level in mice (2001) Journal of Neuroscience Research, 63 (6), pp. 509-515. , DOI 10.1002/jnr.1045; \n\nOlson, H., Betton, G., Robinson, D., Thomas, K., Monro, A., Kolaja, G., Lilly, P., Heller, A., Concordance of the toxicity of pharmaceuticals in humans and in animals (2000) Regulatory Toxicology and Pharmacology, 32, pp. 56-67; \n\nPetkov, V.D., Mosharrof, A.H., Effects of standardized ginseng extract on learning, memory and physical capabilities (1987) The American Journal of Chinese Medicine, 15, pp. 19-29; \n\nRhiouani, H., El-Hilaly, J., Zafar, H.I., Badiaa, L., Acute and sub-chronic toxicity of an aqueous extract of the leaves of Herniaria glabra in rodents (2008) Journal of Ethnopharmacology, 118, pp. 378-386; \n\nShang, W.F., Liu, J.Y., Qi, Y., Xu, L.Z., Cai, R.L., Wu, B., Du, L.J., Effects of KXS on ability of learning and memory in mice (2003) China Journal of Experimental Traditional Medical Formulae, 9, pp. 24-27; \n\nTwaij, H.A.A., Kery, A., Al-Khazraji, N.K., Some pharmacological, toxicological and phytochemical investigations on Centaurea phyllocephala (1983) Journal of Ethnopharmacology, 9 (2-3), pp. 299-314; \n\nVan Miert, A.S.J.P.A.M., The use in animals of drugs licensed for human use only (1986) Comparative Veterinary Pharmacology, Toxicology and Therapy, pp. 489-500. , A.S.J.P.A.M. Van Miert, M.G. Bogaert, M. Debackere, MTP Press Boston; \n\nWang, J., Heijden, R., Spruit, S., Hankermeier, T., Chan, K., Greef, J., Xu, G., Wang, M., Quality and safety of Chinese herbal medicines guided by a systems biology perspective (2009) Journal of Ethnopharmacology, 126, pp. 31-41; \n\nWang, J.L., Liu, P., Wang, D.X., Tu, H.H., Chen, G.Y., The effect of Kai-Xin-San on behavior of chronic stress in rats and PCREB expression in hippocampus (2007) China Journal of Chinese Materia Medica, 32, pp. 1555-1557; \n\nYamaguchi, Y., Higashi, M., Kobayashi, H., Effects of ginsenosides on impaired performance caused by scopolamine in rats (1996) European Journal of Pharmacology, 312 (2), pp. 149-151. , DOI 10.1016/0014-2999(96)00597-3; \n\nZhao, R., McDaniel, W.F., Ginseng improves strategic learning by normal and brain-damaged rats (1998) NeuroReport, 9 (7), pp. 1619-1624", "hasCitationDuplums" : false, "userChangeableUntil" : "2015-01-15T12:25:00.000+0000", "publishDate" : "2014-10-17T11:25:00.000+0000", "directInstitutesForSort" : "", "ownerAuthorCount" : 1, "ownerInstituteCount" : 3, "directInstituteCount" : 0, "authorCount" : 5, "contributorCount" : 0, "hasQualityFactor" : false, "link" : "/api/publication/24248476", "label" : "Mu L-H et al. 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