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disruption in cognitive systems, primarily executive and memory 
functions. However, it is not clear if the development of 
sequence learning is affected by an impaired cognitive system 
and, if so, how. The goal of our study was to investigate the 
development of probabilistic sequence learning, from the initial 
acquisition to consolidation, in MCI and healthy elderly control 
groups. We used the Alternating Serial Reaction Time task (ASRT) 
to measure probabilistic sequence learning. Individuals with MCI 
showed weaker learning performance than the healthy elderly 
group. However, using the reaction times only from the second 
half of each learning block—after the reactivation phase—we 
found intact learning in MCI. Based on the assumption that the 
first part of each learning block is related to 
reactivation/recall processes, we suggest that these processes 
are affected in MCI. The 24-h offline period showed no effect on 
sequence-specific learning in either group but did on general 
skill learning: the healthy elderly group showed offline 
improvement in general reaction times while individuals with MCI 
did not. Our findings deepen our understanding regarding the 
underlying mechanisms and time course of sequence acquisition 
and consolidation.</abstractText>
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          <label>56. Song, S., Howard Jr., J.H., Howard, D.V., Sleep does not benefit probabilistic motor sequence learning (2007) Journal of Neuroscience, 27 (46), pp. 12475-12483</label>
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          <label>57. Song, S., Howard, J.H.J., Howard, D.V., Perceptual sequence learning in a serial reaction time task (2008) Experimental Brain Research, 189 (2), pp. 145-158</label>
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          <label>58. Squire, L.R., Memory systems (1998) C R Acad Sci III, 321 (2-3), pp. 153-156</label>
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          <label>59. Squire, L.R., Zola, S.M., Structure and function of declarative and nondeclarative memory systems (1996) Proceedings of the National Academy of Sciences USA, 93, pp. 13515-13522</label>
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          <label>61. Tariska, P.D., Kiss É, D., Mészáros Á, D., Knolmayer, J.D., A módosított Mini Mental State vizsgálat (1990) Ideggyógyászati Szemle, 43, pp. 443-449</label>
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          <label>62. Tucker, M., McKinley, S., Stickgold, R., Sleep optimizes motor skill in older adults (2011) Journal of the American Geriatrics Society, 59 (4), pp. 603-609</label>
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      <label>Németh D et al. Probabilistic sequence learning in Mild Cognitive Impairment. (2013) FRONTIERS IN HUMAN NEUROSCIENCE 1662-5161 1662-5161 7 JUN</label><template>&lt;div class=&quot;JournalArticle Publication short-list&quot;&gt; &lt;div class=&quot;authors&quot;&gt; &lt;span class=&quot;author-name&quot; mtid=&quot;10000225&quot;&gt; &lt;a href=&quot;/gui2/?type=authors&amp;mode=browse&amp;sel=10000225&quot; target=&quot;_blank&quot;&gt;Németh, D&lt;/a&gt; &lt;/span&gt; &lt;span class=&quot;author-type&quot;&gt; &lt;/span&gt; ; &lt;span class=&quot;author-name&quot; mtid=&quot;10029842&quot;&gt; &lt;a href=&quot;/gui2/?type=authors&amp;mode=browse&amp;sel=10029842&quot; target=&quot;_blank&quot;&gt;Janacsek, K&lt;/a&gt; &lt;/span&gt; &lt;span class=&quot;author-type&quot;&gt; &lt;/span&gt; ; &lt;span class=&quot;author-name&quot; &gt; Király, K &lt;/span&gt; &lt;span class=&quot;author-type&quot;&gt; &lt;/span&gt; ; &lt;span class=&quot;author-name&quot; &gt; Londe, Zs &lt;/span&gt; &lt;span class=&quot;author-type&quot;&gt; &lt;/span&gt; ; &lt;span class=&quot;author-name&quot; 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&lt;div class=&quot;title&quot;&gt;&lt;a href=&quot;/gui2/?mode=browse&amp;params=publication;2360549&quot; target=&quot;_blank&quot;&gt;Probabilistic sequence learning in Mild Cognitive Impairment&lt;/a&gt;&lt;/div&gt;    &lt;div&gt;		&lt;span class=&quot;journal-title&quot;&gt;FRONTIERS IN HUMAN NEUROSCIENCE&lt;/span&gt;

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&lt;div class=&quot;lastModified&quot;&gt;Utolsó módosítás: 2020.12.22. 13:38 Szuper Admin (admin)
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	&lt;pre class=&quot;comment&quot; style=&quot;margin-top: 0; margin-bottom: 0;&quot;&gt;&lt;u&gt;Megjegyzés&lt;/u&gt;: WoS:hiba:000321193900001 2019-03-07 22:31 cikkazonosító nem egyezik&lt;/pre&gt;
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