{ "labelLang" : "hun", "responseDate" : "2024-03-29 11:55", "content" : { "otype" : "JournalArticle", "mtid" : 22684821, "status" : "ADMIN_APPROVED", "published" : true, "unhandledTickets" : 0, "oldTimestamp" : "2018-10-01T21:38:43.000+0000", "deleted" : false, "oldId" : 12684821, "lastRefresh" : "2022-02-24T10:47:04.838+0000", "lastModified" : "2018-10-01T21:38:43.000+0000", "created" : "2012-11-06T13:35:09.000+0000", "creator" : { "otype" : "Author", "mtid" : 10000174, "link" : "/api/author/10000174", "label" : "Szarka András (Biokémia, Biotechnológia)", "familyName" : "Szarka", "givenName" : "András", "published" : true, "oldId" : 10000174, "snippet" : true }, "lastDuplumOK" : "2018-10-20T22:17:49.907+0000", "lastDuplumSearch" : "2018-10-20T22:17:49.907+0000", "adminApproved" : "2016-03-08T08:48:04.000+0000", "adminApprover" : { "otype" : "Admin", "mtid" : 10014931, "link" : "/api/admin/10014931", "label" : "Farkas Andrea (MTMT Központ, admin)", "familyName" : "Farkas", "givenName" : "Andrea", "published" : true, "oldId" : 10014931, "snippet" : true }, "core" : false, "citation" : true, "publicationPending" : false, "type" : { "otype" : "PublicationType", "mtid" : 24, "link" : "/api/publicationtype/24", "label" : "Folyóiratcikk", "code" : 24, "otypeName" : "JournalArticle", "listPosition" : 1, "published" : true, "oldId" : 24, "snippet" : true }, "languages" : [ { "otype" : "Language", "mtid" : 10002, "link" : "/api/language/10002", "label" : "Angol", "name" : "Angol", "nameEng" : "English", "published" : true, "oldId" : 2, "snippet" : true } ], "firstAuthor" : "Gould, NS", "authorships" : [ { "otype" : "PersonAuthorship", "mtid" : 20721223, "link" : "/api/authorship/20721223", "label" : "Gould, NS", "listPosition" : 1, "share" : 0.0, "first" : true, "last" : false, "familyName" : "Gould", "givenName" : "NS", "authorTyped" : true, "editorTyped" : false, "otherTyped" : false, "type" : { "otype" : "AuthorshipType", "mtid" : 1, "link" : "/api/authorshiptype/1", "label" : "Szerző", "code" : 0, "published" : true, "oldId" : 0, "snippet" : true }, "published" : false, "oldId" : 29516023, "snippet" : true }, { "otype" : "PersonAuthorship", "mtid" : 20721224, "link" : "/api/authorship/20721224", "label" : "Day, BJ", "listPosition" : 2, "share" : 0.0, "first" : false, "last" : true, "familyName" : "Day", "givenName" : "BJ", "authorTyped" : true, "editorTyped" : false, "otherTyped" : false, "type" : { "otype" : "AuthorshipType", "mtid" : 1, "link" : "/api/authorshiptype/1", "label" : "Szerző", "code" : 0, "published" : true, "oldId" : 0, "snippet" : true }, "published" : false, "oldId" : 29516022, "snippet" : true } ], "title" : "Targeting maladaptive glutathione responses in lung disease", "identifiers" : [ { "otype" : "PublicationIdentifier", "mtid" : 5442070, "link" : "/api/publicationidentifier/5442070", "label" : "DOI: 10.1016/j.bcp.2010.10.001", "source" : { "otype" : "PlainSource", "mtid" : 6, "link" : "/api/publicationsource/6", "label" : "DOI", "type" : { "otype" : "PublicationSourceType", "mtid" : 10001, "link" : "/api/publicationsourcetype/10001", "label" : "DOI", "mayHaveOa" : true, "published" : true, "snippet" : true }, "name" : "DOI", "nameEng" : "DOI", "linkPattern" : "https://doi.org/@@@", "publiclyVisible" : true, "published" : true, "oldId" : 6, "snippet" : true }, "validState" : "NO", "idValue" : "10.1016/j.bcp.2010.10.001", "realUrl" : "https://doi.org/10.1016%2Fj.bcp.2010.10.001", "published" : false, "oldId" : 2642257, "snippet" : true }, { "otype" : "PublicationIdentifier", "mtid" : 5442068, "link" : "/api/publicationidentifier/5442068", "label" : "WoS: 000286156500001", "source" : { "otype" : "PlainSource", "mtid" : 1, "link" : "/api/publicationsource/1", "label" : "WoS", "type" : { "otype" : "PublicationSourceType", "mtid" : 10003, "link" : "/api/publicationsourcetype/10003", "label" : "Indexelő adatbázis", "mayHaveOa" : false, "published" : true, "snippet" : true }, "name" : "WoS", "nameEng" : "WoS", "linkPattern" : "http://gateway.isiknowledge.com/gateway/Gateway.cgi?&GWVersion=2&SrcAuth=CustomerName&SrcApp=CustomerName&DestLinkType=FullRecord&KeyUT=@@@&DestApp=WOS", "publiclyVisible" : true, "published" : true, "oldId" : 1, "snippet" : true }, "validState" : "NO", "idValue" : "000286156500001", "realUrl" : "http://gateway.isiknowledge.com/gateway/Gateway.cgi?&GWVersion=2&SrcAuth=CustomerName&SrcApp=CustomerName&DestLinkType=FullRecord&KeyUT=000286156500001&DestApp=WOS", "published" : false, "oldId" : 11091727, "snippet" : true }, { "otype" : "PublicationIdentifier", "mtid" : 5442069, "link" : "/api/publicationidentifier/5442069", "label" : "Scopus: 78650180139", "source" : { "otype" : "PlainSource", "mtid" : 3, "link" : "/api/publicationsource/3", "label" : "Scopus", "type" : { "otype" : "PublicationSourceType", "mtid" : 10003, "link" : "/api/publicationsourcetype/10003", "label" : "Indexelő adatbázis", "mayHaveOa" : false, "published" : true, "snippet" : true }, "name" : "Scopus", "linkPattern" : "http://www.scopus.com/record/display.url?origin=inward&eid=2-s2.0-@@@", "publiclyVisible" : true, "published" : true, "oldId" : 3, "snippet" : true }, "validState" : "NO", "idValue" : "78650180139", "realUrl" : "http://www.scopus.com/record/display.url?origin=inward&eid=2-s2.0-78650180139", "published" : false, "oldId" : 2642258, "snippet" : true } ], "journal" : { "otype" : "Journal", "mtid" : 686, "link" : "/api/journal/686", "label" : "BIOCHEMICAL PHARMACOLOGY 0006-2952 1873-2968", "pIssn" : "0006-2952", "eIssn" : "1873-2968", "reviewType" : "REVIEWED", "noIF" : false, "sciIndexed" : true, "scopusIndexed" : true, "lang" : "FOREIGN", "hungarian" : false, "published" : true, "oldId" : 686, "snippet" : true }, "volume" : "81", "issue" : "2", "firstPage" : "187", "lastPage" : "193", "firstPageOrInternalIdForSort" : "187", "pageLength" : 7, "publishedYear" : 2011, "digital" : null, "printed" : null, "sourceYear" : 2012, "packet" : "(Szarka András (Biokémia, élelmiszerkém...); 2012.11.06. 14:33:05)", "foreignEdition" : true, "foreignLanguage" : true, "fullPublication" : false, "conferencePublication" : null, "nationalOrigin" : null, "missingAuthor" : false, "oaType" : "NONE", "oaCheckDate" : "2022-02-24", "oaFree" : false, "citationCount" : 0, "citationCountUnpublished" : 0, "citationCountWoOther" : 0, "independentCitCountWoOther" : 0, "doiCitationCount" : 0, "wosCitationCount" : 0, "scopusCitationCount" : 0, "independentCitationCount" : 0, "unhandledCitationCount" : 0, "citingPubCount" : 0, "independentCitingPubCount" : 0, "unhandledCitingPubCount" : 0, "citedPubCount" : 1, "citedCount" : 1, "references" : [ { "otype" : "Reference", "mtid" : 14807203, "link" : "/api/reference/14807203", "label" : "1. Cantin, A.M., Fells, G.A., Hubbard, R.C., Crystal, R.G., Antioxidant macromolecules in the epithelial lining fluid of the normal human lower respiratory tract (1990) Journal of Clinical Investigation, 86 (3), pp. 962-971", "listPosition" : 1, "published" : false, "snippet" : true }, { "otype" : "Reference", "mtid" : 14807204, "link" : "/api/reference/14807204", "label" : "2. Kelly, F.J., Cotgrove, M., Mudway, I.S., Respiratory tract lining fluid antioxidants: The first line of defence against gaseous pollutants (1996) Cent Eur J Public Health, 4 (SUPPL.), pp. 11-14", "listPosition" : 2, "published" : false, "snippet" : true }, { "otype" : "Reference", "mtid" : 14807205, "link" : "/api/reference/14807205", "label" : "3. Magi, B., Bargagli, E., Bini, L., Rottoli, P., Proteome analysis of bronchoalveolar lavage in lung diseases (2006) Proteomics, 6 (23), pp. 6354-6369., DOI: 10.1002/pmic.200600303", "listPosition" : 3, "doi" : "10.1002/pmic.200600303", "published" : false, "snippet" : true }, { "otype" : "Reference", "mtid" : 14807206, "link" : "/api/reference/14807206", "label" : "4. Noel-Georis, I., Bernard, A., Falmagne, P., Wattiez, R., Database of bronchoalveolar lavage fluid proteins (2002) Journal of Chromatography B: Analytical Technologies in the Biomedical and Life Sciences, 771 (1-2), pp. 221-236. , PII S1570023202001149, DOI: 10.1016/S1570-0232(02)00114-9,", "listPosition" : 4, "doi" : "10.1016/S1570-0232(02)00114-9,", "published" : false, "snippet" : true }, { "otype" : "Reference", "mtid" : 14807207, "link" : "/api/reference/14807207", "label" : "5. Kinnula, V.L., Crapo, J.D., Superoxide dismutases in the lung and human lung diseases (2003) American Journal of Respiratory and Critical Care Medicine, 167 (12), pp. 1600-1619., DOI: 10.1164/rccm.200212-1479SO", "listPosition" : 5, "doi" : "10.1164/rccm.200212-1479SO", "published" : false, "snippet" : true }, { "otype" : "Reference", "mtid" : 14807208, "link" : "/api/reference/14807208", "label" : "6. Cross, C.E., Van Der Vliet, A., O'Neill, C.A., Louie, S., Halliwell, B., Oxidants, antioxidants, and respiratory tract lining fluids (1994) Environ Health Perspect, 102 (SUPPL. 10), pp. 185-191", "listPosition" : 6, "published" : false, "snippet" : true }, { "otype" : "Reference", "mtid" : 14807209, "link" : "/api/reference/14807209", "label" : "7. Cantin, A.M., North, S.L., Hubbard, R.C., Crystal, R.G., Normal alveolar epithelial lining fluid contains high levels of glutathione (1987) Journal of Applied Physiology, 63 (1), pp. 152-157", "listPosition" : 7, "published" : false, "snippet" : true }, { "otype" : "Reference", "mtid" : 14807210, "link" : "/api/reference/14807210", "label" : "8. Behndig, A.F., Blomberg, A., Helleday, R., Duggan, S.T., Kelly, F.J., Mudway, I.S., Antioxidant responses to acute ozone challenge in the healthy human airway (2009) Inhal Toxicol, 21, pp. 933-942", "listPosition" : 8, "published" : false, "snippet" : true }, { "otype" : "Reference", "mtid" : 14807211, "link" : "/api/reference/14807211", "label" : "9. Schock, B.C., Koostra, J., Kwack, S., Hackman, R.M., Van Der Vliet, A., Cross, C.E., Ascorbic acid in nasal and tracheobronchial airway lining fluids (2004) Free Radical Biology and Medicine, 37 (9), pp. 1393-1401. , PII S0891584904005829, DOI: 10.1016/j.freeradbiomed.2004.07.023,", "listPosition" : 9, "doi" : "10.1016/j.freeradbiomed.2004.07.023,", "published" : false, "snippet" : true }, { "otype" : "Reference", "mtid" : 14807212, "link" : "/api/reference/14807212", "label" : "10. Slade, R., Crissman, K., Norwood, J., Hatch, G., Comparison of antioxidant substances in bronchoalveolar lavage cells and fluid from humans, guinea pigs, and rats (1993) Experimental Lung Research, 19 (4), pp. 469-484", "listPosition" : 10, "published" : false, "snippet" : true }, { "otype" : "Reference", "mtid" : 14807213, "link" : "/api/reference/14807213", "label" : "11. Fischer, H., Mechanisms and function of DUOX in epithelia of the lung (2009) Antioxid Redox Signal, 11, pp. 2453-2465", "listPosition" : 11, "published" : false, "snippet" : true }, { "otype" : "Reference", "mtid" : 14807214, "link" : "/api/reference/14807214", "label" : "12. Cantin, A.M., Begin, R., Glutathione and inflammatory disorders of the lung (1991) Lung, 169, pp. 123-138", "listPosition" : 12, "published" : false, "snippet" : true }, { "otype" : "Reference", "mtid" : 14807215, "link" : "/api/reference/14807215", "label" : "13. Morris, P.E., Bernard, G.R., Significance of glutathione in lung disease and implications for therapy (1994) American Journal of the Medical Sciences, 307 (2), pp. 119-127", "listPosition" : 13, "published" : false, "snippet" : true }, { "otype" : "Reference", "mtid" : 14807216, "link" : "/api/reference/14807216", "label" : "14. Leitner, H.M., Kachadourian, R., Day, B.J., Harnessing drug resistance: Using ABC transporter proteins to target cancer cells (2007) Biochemical Pharmacology, 74 (12), pp. 1677-1685. , PII S0006295207003231, DOI: 10.1016/j.bcp.2007.05.014,", "listPosition" : 14, "doi" : "10.1016/j.bcp.2007.05.014,", "published" : false, "snippet" : true }, { "otype" : "Reference", "mtid" : 14807217, "link" : "/api/reference/14807217", "label" : "15. Smith, C.V., Jones, D.P., Guenthner, T.M., Lash, L.H., Lauterburg, B.H., Compartmentation of glutathione: Implications for the study of toxicity and disease (1996) Toxicology and Applied Pharmacology, 140 (1), pp. 1-12., DOI: 10.1006/taap.1996.0191", "listPosition" : 15, "doi" : "10.1006/taap.1996.0191", "published" : false, "snippet" : true }, { "otype" : "Reference", "mtid" : 14807218, "link" : "/api/reference/14807218", "label" : "16. Chikhi, N., Holic, N., Guellaen, G., Laperche, Y., Gamma-glutamyl transpeptidase gene organization and expression: A comparative analysis in rat, mouse, pig and human species (1999) Comparative Biochemistry and Physiology - B Biochemistry and Molecular Biology, 122 (4), pp. 367-380. , PII S0305049199000139, DOI: 10.1016/S0305-0491(99)00013-9,", "listPosition" : 16, "doi" : "10.1016/S0305-0491(99)00013-9,", "published" : false, "snippet" : true }, { "otype" : "Reference", "mtid" : 14807219, "link" : "/api/reference/14807219", "label" : "17. Bai, C., Brown, L.A., Jones, D.P., Glutathione transport by type II cells in perfused rat lung (1994) Am J Physiol, 267, pp. 447-L455", "listPosition" : 17, "published" : false, "snippet" : true }, { "otype" : "Reference", "mtid" : 14807220, "link" : "/api/reference/14807220", "label" : "18. Lash, L.H., Hagen, T.M., Jones, D.P., Exogenous glutathione protects intestinal epithelial cells from oxidative injury (1986) Proceedings of the National Academy of Sciences of the United States of America, 83 (13), pp. 4641-4645", "listPosition" : 18, "published" : false, "snippet" : true }, { "otype" : "Reference", "mtid" : 14807221, "link" : "/api/reference/14807221", "label" : "19. Lash, L.H., Jones, D.P., Transport of glutathione by renal basal-lateral membrane vesicles (1983) Biochemical and Biophysical Research Communications, 112 (1), pp. 55-60", "listPosition" : 19, "published" : false, "snippet" : true }, { "otype" : "Reference", "mtid" : 14807222, "link" : "/api/reference/14807222", "label" : "20. Day, B.J., Van Heeckeren, A.M., Min, E., Velsor, L.W., Role for Cystic Fibrosis Transmembrane Conductance Regulator Protein in A Glutathione Response to Bronchopulmonary Pseudomonas Infection (2004) Infection and Immunity, 72 (4), pp. 2045-2051., DOI: 10.1128/IAI.72.4.2045-2051.2004", "listPosition" : 20, "doi" : "10.1128/IAI.72.4.2045-2051.2004", "published" : false, "snippet" : true }, { "otype" : "Reference", "mtid" : 14807223, "link" : "/api/reference/14807223", "label" : "21. Kariya, C., Leitner, H., Min, E., Van Heeckeren, C., Van Heeckeren, A., Day, B.J., A role for CFTR in the elevation of glutathione levels in the lung by oral glutathione administration (2007) Am J Physiol Lung Cell Mol Physiol, 292, pp. 1590-L1597", "listPosition" : 21, "published" : false, "snippet" : true }, { "otype" : "Reference", "mtid" : 14807224, "link" : "/api/reference/14807224", "label" : "22. Kariya, C., Chu, H.W., Huang, J., Leitner, H., Martin, R.J., Day, B.J., Mycoplasma pneumoniae infection and environmental tobacco smoke inhibit lung glutathione adaptive responses and increase oxidative stress (2008) Infect Immun, 76, pp. 4455-4462", "listPosition" : 22, "published" : false, "snippet" : true }, { "otype" : "Reference", "mtid" : 14807225, "link" : "/api/reference/14807225", "label" : "23. Brechbuhl, H.M., Gould, N., Kachadourian, R., Riekhof, W.R., Voelker, D.R., Day, B.J., Glutathione transport is a unique function of the ATP-binding cassette protein ABCG2 (2010) J Biol Chem, 285, pp. 16582-16587", "listPosition" : 23, "published" : false, "snippet" : true }, { "otype" : "Reference", "mtid" : 14807226, "link" : "/api/reference/14807226", "label" : "24. Haddad, J.J., Glutathione depletion is associated with augmenting a pro-inflammatory signal: Evidence for an antioxidant/pro-oxidant mechanism regulating cytokines in the alveolar epithelium (2000) Cytokines, Cellular and Molecular Therapy, 6 (4), pp. 177-187", "listPosition" : 24, "published" : false, "snippet" : true }, { "otype" : "Reference", "mtid" : 14807227, "link" : "/api/reference/14807227", "label" : "25. Haddad, J.J., Harb, H.L., L-gamma-glutamyl-l-cysteinyl-glycine (glutathione; GSH) and GSH-related enzymes in the regulation of pro- and anti-inflammatory cytokines: A signaling transcriptional scenario for redox(y) immunologic sensor(s)? (2005) Mol Immunol, 42, pp. 987-1014", "listPosition" : 25, "published" : false, "snippet" : true }, { "otype" : "Reference", "mtid" : 14807228, "link" : "/api/reference/14807228", "label" : "26. Drost, E.M., Skwarski, K.M., Sauleda, J., Soler, N., Roca, J., Agusti, A., MacNee, W., Oxidative stress and airway inflammation in severe exacerbations of COPD (2005) Thorax, 60 (4), pp. 293-300., DOI: 10.1136/thx.2004.027946", "listPosition" : 26, "doi" : "10.1136/thx.2004.027946", "published" : false, "snippet" : true }, { "otype" : "Reference", "mtid" : 14807229, "link" : "/api/reference/14807229", "label" : "27. Gould, N.S., Min, E., Gauthier, S., Chu, H.W., Martin, R., Day, B.J., Aging adversely affects the cigarette smoke induced glutathione adaptive response in the lung (2010) Am J Respir Crit Care Med, , doi:, DOI: 10.1162/rccm.201003-0442OC", "listPosition" : 27, "doi" : "10.1162/rccm.201003-0442OC", "published" : false, "snippet" : true }, { "otype" : "Reference", "mtid" : 14807230, "link" : "/api/reference/14807230", "label" : "28. Ito, K., Barnes, P.J., COPD as a disease of accelerated lung aging (2009) Chest, 135, pp. 173-180", "listPosition" : 28, "published" : false, "snippet" : true }, { "otype" : "Reference", "mtid" : 14807231, "link" : "/api/reference/14807231", "label" : "29. Abboud, R.T., Vimalanathan, S., Pathogenesis of COPD. Part I. The role of protease-antiprotease imbalance in emphysema (2008) International Journal of Tuberculosis and Lung Disease, 12 (4), pp. 361-367", "listPosition" : 29, "published" : false, "snippet" : true }, { "otype" : "Reference", "mtid" : 14807232, "link" : "/api/reference/14807232", "label" : "30. Cavarra, E., Lucattelli, M., Gambelli, F., Bartalesi, B., Fineschi, S., Szarka, A., Human SLPI inactivation after cigarette smoke exposure in a new in vivo model of pulmonary oxidative stress (2001) Am J Physiol Lung Cell Mol Physiol, 281, pp. 412-L427", "listPosition" : 30, "published" : false, "snippet" : true }, { "otype" : "Reference", "mtid" : 14807233, "link" : "/api/reference/14807233", "label" : "31. Gadek, J.E., Fells, G.A., Zimmerman, R.L., Antielastases of the human alveolar structures. Implications for the protease-antiprotease theory of emphysema (1981) Journal of Clinical Investigation, 68 (4), pp. 889-898", "listPosition" : 31, "published" : false, "snippet" : true }, { "otype" : "Reference", "mtid" : 14807234, "link" : "/api/reference/14807234", "label" : "32. Cosio, B.G., Agusti, A., Update in chronic obstructive pulmonary disease (2009) Am J Respir Crit Care Med, 181, pp. 655-660", "listPosition" : 32, "published" : false, "snippet" : true }, { "otype" : "Reference", "mtid" : 14807235, "link" : "/api/reference/14807235", "label" : "33. Peto, R., Lopez, A.D., Boreham, J., Thun, M., Heath Jr., C., Mortality from tobacco in developed countries: Indirect estimation from national vital statistics (1992) Lancet, 339, pp. 1268-1278", "listPosition" : 33, "published" : false, "snippet" : true }, { "otype" : "Reference", "mtid" : 14807236, "link" : "/api/reference/14807236", "label" : "34. Snider, G.L., Chronic obstructive pulmonary disease: Risk factors, pathophysiology and pathogenesis (1989) Annual Review of Medicine, 40, pp. 411-429", "listPosition" : 34, "published" : false, "snippet" : true }, { "otype" : "Reference", "mtid" : 14807237, "link" : "/api/reference/14807237", "label" : "35. Janssens, J.P., Pache, J.C., Nicod, L.P., Physiological changes in respiratory function associated with ageing (1999) European Respiratory Journal, 13 (1), pp. 197-205., DOI: 10.1034/j.1399-3003.1999.13a36.x", "listPosition" : 35, "doi" : "10.1034/j.1399-3003.1999.13a36.x", "published" : false, "snippet" : true }, { "otype" : "Reference", "mtid" : 14807238, "link" : "/api/reference/14807238", "label" : "36. MacNee, W., Accelerated lung aging: A novel pathogenic mechanism of chronic obstructive pulmonary disease (COPD) (2009) Biochem Soc Trans, 37, pp. 819-823", "listPosition" : 36, "published" : false, "snippet" : true }, { "otype" : "Reference", "mtid" : 14807239, "link" : "/api/reference/14807239", "label" : "37. Teramoto, S., Fukuchi, Y., Uejima, Y., Teramoto, K., Ito, H., Orimo, H., Age-related changes in the antioxidant screen of the distal lung in mice (1994) Lung, 172 (4), pp. 223-230., DOI: 10.1007/BF00164439", "listPosition" : 37, "doi" : "10.1007/BF00164439", "published" : false, "snippet" : true }, { "otype" : "Reference", "mtid" : 14807240, "link" : "/api/reference/14807240", "label" : "38. Suh, J.H., Shenvi, S.V., Dixon, B.M., Liu, H., Jaiswal, A.K., Liu, R.-M., Hagen, T.M., Decline in transcriptional activity of Nrf2 causes age-related loss of glutathione synthesis, which is reversible with lipoic acid (2004) Proceedings of the National Academy of Sciences of the United States of America, 101 (10), pp. 3381-3386., DOI: 10.1073/pnas.0400282101", "listPosition" : 38, "doi" : "10.1073/pnas.0400282101", "published" : false, "snippet" : true }, { "otype" : "Reference", "mtid" : 14807241, "link" : "/api/reference/14807241", "label" : "39. Berdiev, B.K., Qadri, Y.J., Benos, D.J., Assessment of the CFTR and ENaC association (2009) Mol Biosyst, 5, pp. 123-127", "listPosition" : 39, "published" : false, "snippet" : true }, { "otype" : "Reference", "mtid" : 14807242, "link" : "/api/reference/14807242", "label" : "40. Heijerman, H., Infection and inflammation in cystic fibrosis: A short review (2005) Journal of Cystic Fibrosis, 4 (2 SUPPL.), pp. 3-5. , PII S1569199305000548, DOI: 10.1016/j.jcf.2005.05.005,", "listPosition" : 40, "doi" : "10.1016/j.jcf.2005.05.005,", "published" : false, "snippet" : true }, { "otype" : "Reference", "mtid" : 14807243, "link" : "/api/reference/14807243", "label" : "41. Klebanoff, S.J., Myeloperoxidase: Friend and foe (2005) Journal of Leukocyte Biology, 77 (5), pp. 598-625., DOI: 10.1189/jlb.1204697", "listPosition" : 41, "doi" : "10.1189/jlb.1204697", "published" : false, "snippet" : true }, { "otype" : "Reference", "mtid" : 14807244, "link" : "/api/reference/14807244", "label" : "42. This joint statement of the American Thoracic Society (ATS), and the European Respiratory Society (ERS) was adopted by the ATS board of directors, June 2001 and by the ERS Executive Committee, June 2001 (2002) Am J Respir Crit Care Med, 165, pp. 277-304. , American Thoracic Society/European Respiratory Society International Multidisciplinary Consensus Classification of the Idiopathic Interstitial Pneumonias", "listPosition" : 42, "published" : false, "snippet" : true }, { "otype" : "Reference", "mtid" : 14807245, "link" : "/api/reference/14807245", "label" : "43. Cantin, A.M., Hubbard, R.C., Crystal, R.G., Glutathione deficiency in the epithelial lining fluid of the lower respiratory tract in idiopathic pulmonary fibrosis (1989) American Review of Respiratory Disease, 139 (2), pp. 370-372", "listPosition" : 43, "published" : false, "snippet" : true }, { "otype" : "Reference", "mtid" : 14807246, "link" : "/api/reference/14807246", "label" : "44. Borok, Z., Buhl, R., Grimes, G.J., Bokser, A.D., Hubbard, R.C., Holroyd, K.J., Effect of glutathione aerosol on oxidant-antioxidant imbalance in idiopathic pulmonary fibrosis (1991) Lancet, 338, pp. 215-216", "listPosition" : 44, "published" : false, "snippet" : true }, { "otype" : "Reference", "mtid" : 14807247, "link" : "/api/reference/14807247", "label" : "45. Liu, R.M., Gaston Pravia, K.A., Oxidative stress and glutathione in TGF-beta-mediated fibrogenesis (2010) Free Radic Biol Med, 48, pp. 1-15", "listPosition" : 45, "published" : false, "snippet" : true }, { "otype" : "Reference", "mtid" : 14807248, "link" : "/api/reference/14807248", "label" : "46. Jardine, H., MacNee, W., Donaldson, K., Rahman, I., Molecular mechanism of transforming growth factor (TGF)- β 1-induced glutathione depletion in alveolar epithelial cells. Involvement of AP-1/ARE and Fra-1 (2002) Journal of Biological Chemistry, 277 (24), pp. 21158-21166., DOI: 10.1074/jbc.M112145200", "listPosition" : 46, "doi" : "10.1074/jbc.M112145200", "published" : false, "snippet" : true }, { "otype" : "Reference", "mtid" : 14807249, "link" : "/api/reference/14807249", "label" : "47. Arsalane, K., Dubois, C.M., Muanza, T., Begin, R., Boudreau, F., Asselin, C., Cantin, A.M., Transforming Growth Factor-β 1 Is a Potent Inhibitor of Glutathione Synthesis in the Lung Epithelial Cell Line A549: Transcriptional Effect on the GSH Rate-limiting Enzyme γ-Glutamylcysteine Synthetase (1997) American Journal of Respiratory Cell and Molecular Biology, 17 (5), pp. 599-607", "listPosition" : 47, "published" : false, "snippet" : true }, { "otype" : "Reference", "mtid" : 14807250, "link" : "/api/reference/14807250", "label" : "48. Liu, R.M., Liu, Y., Forman, H.J., Olman, M., Tarpey, M.M., Glutathione regulates transforming growth factor-beta-stimulated collagen production in fibroblasts (2004) Am J Physiol Lung Cell Mol Physiol, 286, pp. 121-L128", "listPosition" : 48, "published" : false, "snippet" : true }, { "otype" : "Reference", "mtid" : 14807251, "link" : "/api/reference/14807251", "label" : "49. Aw, T.Y., Wierzbicka, G., Jones, D.P., Oral glutathione increases tissue glutathione in vivo (1991) Chem Biol Interact, 80, pp. 89-97", "listPosition" : 49, "published" : false, "snippet" : true }, { "otype" : "Reference", "mtid" : 14807252, "link" : "/api/reference/14807252", "label" : "50. Hagen, T.M., Wierzbicka, G.T., Sillau, A.H., Bowman, B.B., Jones, D.P., Bioavailability of dietary glutathione: Effect on plasma concentration (1990) Am J Physiol, 259, pp. 524-G529", "listPosition" : 50, "published" : false, "snippet" : true }, { "otype" : "Reference", "mtid" : 14807253, "link" : "/api/reference/14807253", "label" : "51. Bishop, C., Hudson, V.M., Hilton, S.C., Wilde, C., A pilot study of the effect of inhaled buffered reduced glutathione on the clinical status of patients with cystic fibrosis (2005) Chest, 127 (1), pp. 308-317., DOI: 10.1378/chest.127.1.308", "listPosition" : 51, "doi" : "10.1378/chest.127.1.308", "published" : false, "snippet" : true }, { "otype" : "Reference", "mtid" : 14807254, "link" : "/api/reference/14807254", "label" : "52. Roum, J.H., Borok, Z., McElvaney, N.G., Grimes, G.J., Bokser, A.D., Buhl, R., Crystal, R.G., Glutathione aerosol suppresses lung epithelial surface inflammatory cell-derived oxidants in cystic fibrosis (1999) Journal of Applied Physiology, 87 (1), pp. 438-443", "listPosition" : 52, "published" : false, "snippet" : true }, { "otype" : "Reference", "mtid" : 14807255, "link" : "/api/reference/14807255", "label" : "53. Pela, R., Calcagni, A.M., Subiaco, S., Isidori, P., Tubaldi, A., Sanguinetti, C.M., N-acetylcysteine reduces the exacerbation rate in patients with moderate to severe COPD (1999) Respiration, 66, pp. 495-500", "listPosition" : 53, "published" : false, "snippet" : true }, { "otype" : "Reference", "mtid" : 14807256, "link" : "/api/reference/14807256", "label" : "54. Behr, J., Maier, K., Degenkolb, B., Krombach, F., Vogelmeier, C., Antioxidative and clinical effects of high-dose N-acetylcysteine in fibrosing alveolitis. Adjunctive therapy to maintenance immunosuppression (1997) American Journal of Respiratory and Critical Care Medicine, 156 (6), pp. 1897-1901", "listPosition" : 54, "published" : false, "snippet" : true }, { "otype" : "Reference", "mtid" : 14807257, "link" : "/api/reference/14807257", "label" : "55. Meyer, A., Buhl, R., Magnussen, H., The effect of oral N-acetylcysteine on lung glutathione levels in idiopathic pulmonary fibrosis (1994) European Respiratory Journal, 7 (3), pp. 431-436", "listPosition" : 55, "published" : false, "snippet" : true }, { "otype" : "Reference", "mtid" : 14807258, "link" : "/api/reference/14807258", "label" : "56. Hagiwara, S.-I., Ishii, Y., Kitamura, S., Aerosolized administration of N-acetylcysteine attenuates lung fibrosis induced by bleomycin in mice (2000) American Journal of Respiratory and Critical Care Medicine, 162 (1), pp. 225-231", "listPosition" : 56, "published" : false, "snippet" : true }, { "otype" : "Reference", "mtid" : 14807259, "link" : "/api/reference/14807259", "label" : "57. Tomioka, H., Kuwata, Y., Imanaka, K., Hashimoto, K., Ohnishi, H., Tada, K., Sakamoto, H., Iwasaki, H., A pilot study of aerosolized N-acetylcysteine for idiopathic pulmonary fibrosis (2005) Respirology, 10 (4), pp. 449-455., DOI: 10.1111/j.1440-1843.2005.00725.x", "listPosition" : 57, "doi" : "10.1111/j.1440-1843.2005.00725.x", "published" : false, "snippet" : true }, { "otype" : "Reference", "mtid" : 14807260, "link" : "/api/reference/14807260", "label" : "58. Fahey, J.W., Talalay, P., Antioxidant functions of sulforaphane: A potent inducer of phase II detoxication enzymes (1999) Food and Chemical Toxicology, 37 (9-10), pp. 973-979. , PII S0278691599000824, DOI: 10.1016/S0278-6915(99)00082-4,", "listPosition" : 58, "doi" : "10.1016/S0278-6915(99)00082-4,", "published" : false, "snippet" : true }, { "otype" : "Reference", "mtid" : 14807261, "link" : "/api/reference/14807261", "label" : "59. Ritz, S.A., Wan, J., Diaz-Sanchez, D., Sulforaphane-stimulated phase II enzyme induction inhibits cytokine production by airway epithelial cells stimulated with diesel extract (2007) Am J Physiol Lung Cell Mol Physiol, 292, pp. 33-L39", "listPosition" : 59, "published" : false, "snippet" : true }, { "otype" : "Reference", "mtid" : 14807262, "link" : "/api/reference/14807262", "label" : "60. Liby, K., Hock, T., Yore, M.M., Suh, N., Place, A.E., Risingsong, R., Williams, C.R., Sporn, M.B., The synthetic triterpenoids, CDDO and CDDO-imidazolide, are potent inducers of heme oxygenase-1 and Nrf2/ARE signaling (2005) Cancer Research, 65 (11), pp. 4789-4798., DOI: 10.1158/0008-5472.CAN-04-4539", "listPosition" : 60, "doi" : "10.1158/0008-5472.CAN-04-4539", "published" : false, "snippet" : true }, { "otype" : "Reference", "mtid" : 14807263, "link" : "/api/reference/14807263", "label" : "61. Nichols, D.P., Ziady, A.G., Shank, S.L., Eastman, J.F., Davis, P.B., The triterpenoid CDDO limits inflammation in preclinical models of cystic fibrosis lung disease (2009) Am J Physiol Lung Cell Mol Physiol, 297, pp. 828-L836", "listPosition" : 61, "published" : false, "snippet" : true }, { "otype" : "Reference", "mtid" : 14807264, "link" : "/api/reference/14807264", "label" : "62. Reddy, N.M., Suryanaraya, V., Yates, M.S., Kleeberger, S.R., Hassoun, P.M., Yamamoto, M., The triterpenoid CDDO-imidazolide confers potent protection against hyperoxic acute lung injury in mice (2009) Am J Respir Crit Care Med, 180, pp. 867-874", "listPosition" : 62, "published" : false, "snippet" : true }, { "otype" : "Reference", "mtid" : 14807265, "link" : "/api/reference/14807265", "label" : "63. Sussan, T.E., Rangasamy, T., Blake, D.J., Malhotra, D., El-Haddad, H., Bedja, D., Targeting Nrf2 with the triterpenoid CDDO-imidazolide attenuates cigarette smoke-induced emphysema and cardiac dysfunction in mice (2009) Proc Natl Acad Sci USA, 106, pp. 250-255", "listPosition" : 63, "published" : false, "snippet" : true }, { "otype" : "Reference", "mtid" : 14807266, "link" : "/api/reference/14807266", "label" : "64. To, C., Kulkarni, S., Pawson, T., Honda, T., Gribble, G.W., Sporn, M.B., The synthetic triterpenoid 2-cyano-3,12-dioxooleana-1,9-dien-28-oic acid-imidazolide alters transforming growth factor beta-dependent signaling and cell migration by affecting the cytoskeleton and the polarity complex (2008) J Biol Chem, 283, pp. 11700-11713", "listPosition" : 64, "published" : false, "snippet" : true }, { "otype" : "Reference", "mtid" : 14807267, "link" : "/api/reference/14807267", "label" : "65. Bridgeman, M.M.E., Marsden, M., Selby, C., Morrison, D., MacNee, W., Effect of N-acetyl cysteine on the concentrations of thiols in plasma, bronchoalveolar lavage fluid, and lung tissue (1994) Thorax, 49 (7), pp. 670-675", "listPosition" : 65, "published" : false, "snippet" : true }, { "otype" : "Reference", "mtid" : 14807268, "link" : "/api/reference/14807268", "label" : "66. Pacht, E.R., Timerman, A.P., Lykens, M.G., Merola, A.J., Deficiency of alveolar fluid glutathione in patients with sepsis and the adult respiratory distress syndrome (1991) Chest, 100, pp. 1397-1403", "listPosition" : 66, "published" : false, "snippet" : true }, { "otype" : "Reference", "mtid" : 14807269, "link" : "/api/reference/14807269", "label" : "67. Baz, M.A., Tapson, V.F., Roggli, V.L., Van Trigt, P., Piantadosi, C.A., Glutathione depletion in epithelial lining fluid of lung allograft patients (1996) American Journal of Respiratory and Critical Care Medicine, 153 (2), pp. 742-746", "listPosition" : 67, "published" : false, "snippet" : true }, { "otype" : "Reference", "mtid" : 14807270, "link" : "/api/reference/14807270", "label" : "68. Roum, J.H., Buhl, R., McElvaney, N.G., Borok, Z., Crystal, R.G., Systemic deficiency of glutathione in cystic fibrosis (1993) Journal of Applied Physiology, 75 (6), pp. 2419-2424", "listPosition" : 68, "published" : false, "snippet" : true }, { "otype" : "Reference", "mtid" : 14807271, "link" : "/api/reference/14807271", "label" : "69. Pacht, E.R., Diaz, P., Clanton, T., Hart, J., Gadek, J.E., Alveolar fluid glutathione decreases in asymptomatic HIV-seropositive subjects over time (1997) Chest, 112 (3), pp. 785-788", "listPosition" : 69, "published" : false, "snippet" : true }, { "otype" : "Reference", "mtid" : 14807272, "link" : "/api/reference/14807272", "label" : "70. Visca, A., Bishop, C.T., Hilton, S.C., Hudson, V.M., Improvement in clinical markers in CF patients using a reduced glutathione regimen: An uncontrolled, observational study (2008) J Cyst Fibros, 7, pp. 433-436", "listPosition" : 70, "published" : false, "snippet" : true }, { "otype" : "Reference", "mtid" : 14807273, "link" : "/api/reference/14807273", "label" : "71. Witschi, A., Reddy, S., Stofer, B., Lauterburg, B.H., The systemic availability of oral glutathione (1992) Eur J Clin Pharmacol, 43, pp. 667-669", "listPosition" : 71, "published" : false, "snippet" : true }, { "otype" : "Reference", "mtid" : 14807274, "link" : "/api/reference/14807274", "label" : "72. Griese, M., Ramakers, J., Krasselt, A., Starosta, V., Van Koningsbruggen, S., Fischer, R., Ratjen, F., Scheuch, G., Improvement of alveolar glutathione and lung function but not oxidative state in cystic fibrosis (2004) American Journal of Respiratory and Critical Care Medicine, 169 (7), pp. 822-828", "listPosition" : 72, "published" : false, "snippet" : true }, { "otype" : "Reference", "mtid" : 14807275, "link" : "/api/reference/14807275", "label" : "73. Kasielski, M., Nowak, D., Long-term administration of N-acetylcysteine decreases hydrogen peroxide exhalation in subjects with chronic obstructive pulmonary disease (2001) Respiratory Medicine, 95 (6), pp. 448-456., DOI: 10.1053/rmed.2001.1066", "listPosition" : 73, "doi" : "10.1053/rmed.2001.1066", "published" : false, "snippet" : true } ], "hasCitationDuplums" : false, "userChangeableUntil" : "2016-03-08T08:48:04.000+0000", "publishDate" : "2012-11-06T13:51:06.000+0000", "directInstitutesForSort" : "", "ownerAuthorCount" : 1, "ownerInstituteCount" : 14, "directInstituteCount" : 0, "authorCount" : 2, "contributorCount" : 0, "hasQualityFactor" : false, "link" : "/api/publication/22684821", "label" : "Gould NS et al. Targeting maladaptive glutathione responses in lung disease. (2011) BIOCHEMICAL PHARMACOLOGY 0006-2952 1873-2968 81 2 187-193", "template" : "