https://m2.mtmt.hu/ hun 2026-05-02 09:47 JournalArticle 1880701 VALIDATED true 0 2016-04-12T08:58:25.000+0000 false 1880701 2026-02-05T11:05:15.734+0000 2021-06-02T13:17:30.434+0000 2012-03-01T13:29:50.000+0000 true 1405456 Tulassay Zsolt /api/author/1405456 Author true 1405456 2023-09-26T11:00:33.841+0000 2023-09-26T11:00:33.841+0000 2014-11-05T13:58:35.000+0000 true 10033956 Ruttkay Szilvia /api/admin/10033956 Admin true 10033956 2021-06-02T13:17:30.443+0000 true 10026589 Tichy Rita /api/admin/10026589 Admin true 10026589 true false true 24 24 /api/publicationtype/24 PublicationType 1 true 24 JournalArticle true 1134514 Survey paper true 24 24 /api/publicationtype/24 PublicationType 1 true 24 JournalArticle /api/subtype/1134514 Összefoglaló cikk SubType 102 true 1134514 true 1 /api/category/1 Category true 1 Gyorffy, B A "multiple testing" problémája és a genomiális kísérletekre alkalmazott megoldások The problem of multiple testing and solutions for genome-wide studies true true /api/journal/1035675 REVIEWED true true 1035675 false 1035675 true 0030-6002 1788-6120 Journal HUNGARIAN 146 12 559 563 559 5 2005 The problem of multiple testing and its solutions for genome-wide studies. Even if there is no real change, the traditional p = 0.05 can cause 5% of the investigated tests being reported significant. Multiple testing corrections have been developed to solve this problem. Here the authors describe the one-step (Bonferroni), multi-step (step-down and step-up) and graphical methods. However, sometimes a correction for multiple testing creates more problems, than it solves: the universal null hypothesis is of little interest, the exact number of investigations to be adjusted for can not determined and the probability of type II error increases. For these reasons the authors suggest not to perform multiple testing corrections routinely. The calculation of the false discovery rate is a new method for genome-wide studies. Here the p value is substituted by the q value, which also shows the level of significance. The q value belonging to a measurement is the proportion of false positive measurements when we accept it as significant. The authors propose using the q value instead of the p value in genome-wide studies. 2012 235093 false false true false true false NONE 2026-02-05 false true 10026589 Tichy Rita /api/admin/10026589 Admin true 10026589 39 0 37 30 7 37 37 33 36 37 37 30 30 32 7 0 39 32 37 30 0 0 0 Folyóiratcikk Journal Article 24 37 Könyvrészlet Chapter in Book 25 0 Könyv Book 23 0 Egyéb konferenciaközlemény Conference paper 31 0 Egyéb konferenciakötet Conference proceedings 32 0 Oltalmi formák Protection forms 26 0 Disszertáció Thesis 28 1 Egyéb Miscellaneous 29 1 Alkotás Achievement 22 0 Kutatási adat Research data 33 0 Folyóiratcikk Journal Article 24 0 0 0 Könyvrészlet Chapter in Book 25 0 0 0 Könyv Book 23 0 0 0 Egyéb konferenciaközlemény Conference paper 31 0 0 0 Egyéb konferenciakötet Conference proceedings 32 0 0 0 Oltalmi formák Protection forms 26 0 0 0 Disszertáció Thesis 28 0 0 0 Egyéb Miscellaneous 29 0 0 0 Alkotás Achievement 22 0 0 0 Kutatási adat Research data 33 0 0 0 2008 0 2 2 2 2 2009 0 2 1 2 1 2010 0 1 1 1 1 2011 0 2 2 2 2 2012 0 3 2 3 2 2013 0 1 0 1 0 2014 0 2 2 2 2 2015 0 1 1 1 1 2016 0 6 4 6 4 2017 0 3 3 3 3 2018 0 2 1 2 1 2019 0 4 3 4 3 2020 0 2 2 2 2 2021 0 5 5 5 5 2022 0 2 2 2 2 2023 0 0 0 0 0 2024 0 0 0 0 0 2025 0 1 1 1 1 Q3 A false false false false 2014-11-05T13:58:35.000+0000 2013-02-23T19:18:00.000+0000 II. Sz. Belgyógyászati Klinika (SE / AOK / K) 2 29 1 3 0 false Language 10001 /api/language/10001 Magyar Hungarian true 1 true PersonAuthorship 2515001 /api/authorship/2515001 1 0.333 true false true Author 10000109 /api/author/10000109 Győrffy Balázs true 10000109 true Gyorffy B true false false AuthorshipType 1 /api/authorshiptype/1 0 true 0 true false 14531462 true PersonAuthorship 2515002 /api/authorship/2515002 2 0.33333334 false false Gyorffy A true false false AuthorshipType 1 /api/authorshiptype/1 0 true 0 true false 14531461 true PersonAuthorship 2515003 /api/authorship/2515003 3 0.333 false true Author 1405456 /api/author/1405456 Tulassay Zsolt true 1405456 true Tulassay Z true false false AuthorshipType 1 /api/authorshiptype/1 0 true 0 true false 14531460 true PublicationIdentifier 491924 /api/publicationidentifier/491924 PlainSource 3 /api/publicationsource/3 PublicationSourceType 10003 /api/publicationsourcetype/10003 false true true Scopus Scopus http://www.scopus.com/record/display.url?origin=inward&eid=2-s2.0-@@@ true true 3 true false IDENTICAL 19044384381 http://www.scopus.com/record/display.url?origin=inward&eid=2-s2.0-19044384381 false 298522 true PublicationIdentifier 491925 /api/publicationidentifier/491925 PlainSource 17 /api/publicationsource/17 PublicationSourceType 10003 /api/publicationsourcetype/10003 false true true PubMed PubMed http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db=PubMed&list_uids=@@@&dopt=Abstract true true 17 true false IDENTICAL 15853065 http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db=PubMed&list_uids=15853065&dopt=Abstract false 298523 true PublicationIdentifier 491926 /api/publicationidentifier/491926 PlainSource 70 /api/publicationsource/70 PublicationSourceType 10003 /api/publicationsourcetype/10003 false true true MOB MOB https://mob.aeek.hu/detailsperm.jsp?PERMID=@@@ true true 70 true false IDENTICAL 75389 https://mob.aeek.hu/detailsperm.jsp?PERMID=75389 false 985315 true Classification 12548 /api/classification/12548 true true Classification 12215 /api/classification/12215 true true Keyword 65 /api/keyword/65 true 65 true Keyword 3539 /api/keyword/3539 true 3539 true Keyword 8107 /api/keyword/8107 true 8107 true Keyword 10611 /api/keyword/10611 true 10611 true Keyword 20198 /api/keyword/20198 true 20198 true Keyword 1054981 /api/keyword/1054981 true 1054981 true Keyword 1061209 /api/keyword/1061209 true 1061209 true Keyword 1061210 /api/keyword/1061210 true 1061210 true MtaRating 10487092 /api/mtarating/10487092 RatingType 10026 /api/ratingtype/10026 PsziTB Institute 14108 /api/institute/14108 0 false true false Pszichológiai Tudományos Bizottság Committee on Psychology true 14108 true true true A true true MtaRating 11507998 /api/mtarating/11507998 RatingType 10011 /api/ratingtype/10011 DEM Institute 19060 /api/institute/19060 0 false true false Demográfiai Osztályközi Állandó Bizottság Committee on Demography true 19060 true true true A hazai false true SjrRating 5971440 /api/sjrrating/5971440 1812 0.74 journal RatingType 10002 /api/ratingtype/10002 sjr true true ClassificationExternal 2701 /api/classificationexternal/2701 true 2701 true Q3 DIRECT true 5971440 true /api/publication/1880701 <div class="JournalArticle Publication long-list"> <div class="authors"> <img title="Forrásközlemény" style="float: left" src="/frontend/resources/grid/publication-core-icon.png"> <div class="autype autype0"> <span class="author-name" mtid="10000109"><a href="/gui2/?type=authors&mode=browse&sel=10000109" target="_blank">Gyorffy B ✉ (<span class="authorship-author-name">Győrffy Balázs</span> <span class="authorAux-mtmt"> Onkológia</span>) </a> </span> ;&nbsp;&nbsp;&nbsp; <span class="author-name" >Gyorffy A </span> ;&nbsp;&nbsp;&nbsp; <span class="author-name" mtid="1405456"><a href="/gui2/?type=authors&mode=browse&sel=1405456" target="_blank">Tulassay Z (<span class="authorship-author-name">Tulassay Zsolt</span> <span class="authorAux-mtmt"> belgyógyászat, gastroenterologia</span>) </a> </span> <span class="author-affil"><span title="Semmelweis Egyetem">SE</span>/<span title="Általános Orvostudományi Kar">AOK</span>/<span title="Klinikum">K</span>/II. 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Belgyógyászati Klinika</span> </div> </div> <div class="title"><a href="/gui2/?mode=browse&params=publication;1880701" target="_blank">A "multiple testing" problémája és a genomiális kísérletekre alkalmazott megoldások</a></div> <div> <span class="journal-title">ORVOSI HETILAP</span> <span class="journal-issn">(<a target="_blank" href="https://portal.issn.org/resource/ISSN/0030-6002">0030-6002</a> <a target="_blank" href="https://portal.issn.org/resource/ISSN/1788-6120">1788-6120</a>)</span>: <span class="journal-volume">146</span> <span class="journal-issue">12</span> <span class="page"> pp 559-563 </span> <span class="year">(2005)</span> </div> <div class="pub-footer"> <span class="language" xmlns="http://www.w3.org/1999/html">Nyelv: Magyar | </span> <span class="identifiers"> <span class="id identifier oa_none" title="none"> <a style="color:blue" title="19044384381" target="_blank" href="http://www.scopus.com/record/display.url?origin=inward&eid=2-s2.0-19044384381"> Scopus </a> </span> <span class="id identifier oa_none" title="none"> <a style="color:blue" title="15853065" target="_blank" href="http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db=PubMed&list_uids=15853065&dopt=Abstract"> PubMed </a> </span> <span class="id identifier oa_none" title="none"> <a style="color:blue" title="75389" target="_blank" href="https://mob.aeek.hu/detailsperm.jsp?PERMID=75389"> MOB </a> </span> </span> <OnlyViewableByAuthor><div class="ratings"> <div class="journal-subject">Folyóirat szakterülete: Scopus - Medicine (miscellaneous)&nbsp;&nbsp;&nbsp;SJR indikátor:&nbsp;Q3</div> <div class="journal-subject">Pszichológiai Tudományos Bizottság II. FTO PsziTB [1901-]&nbsp;&nbsp;&nbsp;A</div> <div class="journal-subject">Demográfiai Osztályközi Állandó Bizottság IXGJO DEM [1901-]&nbsp;&nbsp;&nbsp;A hazai</div> </div></OnlyViewableByAuthor> <div class="publication-citation" style="margin-left: 0.5cm;"> <span title="Nyilvános idézőközlemények összesen, említések nélkül" class="citingPub-count">Nyilvános idéző összesen: 39</span> | Független: 32 | Függő: 7 | Nem jelölt: 0 | WoS jelölt: 33 | Scopus jelölt:&nbsp;36 | WoS/Scopus jelölt:&nbsp;37 | DOI jelölt:&nbsp;37 </div> <div class="mtid"><span class="long-pub-mtid">Közlemény: 1880701</span> | <span class="status-data status-VALIDATED"> Egyeztetett </span> <span class="oldId">Régi azonosító: 1880701</span> | Forrás | <span class="type-subtype">Folyóiratcikk ( Összefoglaló cikk ) </span> | <span class="pub-category">Tudományos</span> | <span class="publication-sourceOfData">MEDLINE</span> </div> <div class="lastModified">Utolsó módosítás: 2021.06.02. 15:17 Tichy Rita (SE_KK_Admin5_TR, admin) </div> </div></div>