https://m2.mtmt.hu/ hun 2026-07-27 20:53 JournalArticle 1835872 VALIDATED true 0 2018-03-03T12:05:23.000+0000 false 1835872 2026-06-11T13:44:36.200+0000 2022-02-23T18:06:57.165+0000 2012-01-31T15:28:00.000+0000 true 10011064 Kerpel-Fronius Sándor /api/author/10011064 Author true 10011064 2025-07-07T13:18:30.133+0000 2025-07-07T13:18:30.133+0000 2022-02-23T18:06:57.173+0000 true 10026589 Tichy Rita /api/admin/10026589 Admin true 10026589 true false true 24 24 /api/publicationtype/24 PublicationType 1 true 24 JournalArticle true 1134514 Survey paper true 24 24 /api/publicationtype/24 PublicationType 1 true 24 JournalArticle /api/subtype/1134514 Összefoglaló cikk SubType 102 true 1134514 true 1 /api/category/1 Category true 1 Kerpel-Fronius, S A hazai referencia gyógyszerárkeacute;pzés orvosszakmai problémái [Medical problems associated with the national reference pricing system in Hungary]. true true /api/journal/1035675 REVIEWED true true 1035675 false 1035675 true 0030-6002 1788-6120 Journal HUNGARIAN 145 17 913 918 913 6 2004 The author analyses the medical problems associated with the proposed reference pricing system prepared for the 2004 pharmaceutical price and reimbursement negotiations by the Hungarian National Health Insurance Fund (HNIF). In case of drugs containing identical active ingredients the author does not consider it acceptable that from the criteria of reference grouping bioequivalence was omitted, since bioequivalence is the basic clinical pharmacologic principle underlying the safe utilization of generic drugs. The proposal introduces in Hungary the therapeutic reference pricing for drugs belonging to the same ATC 5 level group, having different chemical structures but identical mechanisms of action. The products are listed according to their defined daily dose (DDD) and the arithmetic mean of the cheapest products giving together 50% market share is calculated. Each ATC 5 group has a given per cent reimbursement level and the fixed amount paid by the HNIF for all drugs in the group is defined as the given percentage of the mean price. This sum is reimbursed irrespective whether the products are patent protected or not, furthermore those drugs whose price is three times higher than the fixed mean price are excluded from the reimbursement system. As a result the patients' co-payment for the more expensive drugs will be significantly increased in the future. The basis of the therapeutic reference price is the assumption that the outcome of the treatment will be the same using drugs with the same mechanism of action. However, this assumption lacks valid scientific proof. According to the author, the proposed budget centric reference pricing system, which does not take into account the differing clinical pharmacologic profiles of the drugs, will significantly inhibit the use of new, innovative drugs, the establishment and continuous improvement of truly cost-effective patient care. Several alternative approaches are proposed for controlling drug budget. Finally the author recommends that a Committee should be established to develop a comprehensive proposal for the reorganization of the pricing and reimbursement system of the drugs available for general and/or hospital use, and for the follow-up of the health care effects of these measures. 2012 (Kerpel-Fronius Sándor (Klinikai farmakológia); 2012.01.31. 16:25:33) false false true false true false NONE 2026-06-11 false true 10011064 Kerpel-Fronius Sándor /api/author/10011064 Author true 10011064 4 0 4 4 4 3 4 4 4 4 4 4 4 4 0 0 4 4 4 4 0 0 0 Folyóiratcikk Journal Article 24 4 Könyvrészlet Chapter in Book 25 0 Könyv Book 23 0 Egyéb konferenciaközlemény Conference paper 31 0 Egyéb konferenciakötet Conference proceedings 32 0 Oltalmi formák Protection forms 26 0 Disszertáció Thesis 28 0 Egyéb Miscellaneous 29 0 Alkotás Achievement 22 0 Kutatási adat Research data 33 0 Folyóiratcikk Journal Article 24 0 0 0 Könyvrészlet Chapter in Book 25 0 0 0 Könyv Book 23 0 0 0 Egyéb konferenciaközlemény Conference paper 31 0 0 0 Egyéb konferenciakötet Conference proceedings 32 0 0 0 Oltalmi formák Protection forms 26 0 0 0 Disszertáció Thesis 28 0 0 0 Egyéb Miscellaneous 29 0 0 0 Alkotás Achievement 22 0 0 0 Kutatási adat Research data 33 0 0 0 2007 0 1 1 1 1 2008 0 0 0 0 0 2009 0 0 0 0 0 2010 0 0 0 0 0 2011 0 0 0 0 0 2012 0 0 0 0 0 2013 0 0 0 0 0 2014 0 0 0 0 0 2015 0 0 0 0 0 2016 0 0 0 0 0 2017 0 0 0 0 0 2018 0 1 1 1 1 2019 0 0 0 0 0 2020 0 0 0 0 0 2021 0 0 0 0 0 2022 0 0 0 0 0 2023 0 2 2 2 2 Q3 A false false false false 2012-10-06T14:42:54.000+0000 2012-07-08T14:42:54.000+0000 Farmakológiai és Farmakoterápiás Intézet (SE / AOK / I) 1 4 1 1 0 false Language 10001 /api/language/10001 Magyar Hungarian true 1 true PersonAuthorship 2383448 /api/authorship/2383448 1 1.0 true false Author 10011064 /api/author/10011064 Kerpel-Fronius Sándor true 10011064 true Kerpel-Fronius S true false false AuthorshipType 1 /api/authorshiptype/1 0 true 0 true false 14273384 true PublicationIdentifier 472340 /api/publicationidentifier/472340 PlainSource 3 /api/publicationsource/3 PublicationSourceType 10003 /api/publicationsourcetype/10003 false true true Scopus Scopus http://www.scopus.com/record/display.url?origin=inward&eid=2-s2.0-@@@ true true 3 true false IDENTICAL 3042572883 http://www.scopus.com/record/display.url?origin=inward&eid=2-s2.0-3042572883 false 282546 true PublicationIdentifier 472341 /api/publicationidentifier/472341 PlainSource 17 /api/publicationsource/17 PublicationSourceType 10003 /api/publicationsourcetype/10003 false true true PubMed PubMed http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db=PubMed&list_uids=@@@&dopt=Abstract true true 17 true false IDENTICAL 15170969 http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db=PubMed&list_uids=15170969&dopt=Abstract false 282547 true PublicationIdentifier 472342 /api/publicationidentifier/472342 PlainSource 70 /api/publicationsource/70 PublicationSourceType 10003 /api/publicationsourcetype/10003 false true true MOB MOB https://mob.aeek.hu/detailsperm.jsp?PERMID=@@@ true true 70 true false IDENTICAL 73594 https://mob.aeek.hu/detailsperm.jsp?PERMID=73594 false 1733948 true Classification 12548 /api/classification/12548 true true Classification 12215 /api/classification/12215 true true Keyword 65 /api/keyword/65 true 65 true Keyword 3374 /api/keyword/3374 true 3374 true Keyword 10879 /api/keyword/10879 true 10879 true Keyword 1041806 /api/keyword/1041806 true 1041806 true Keyword 1111303 /api/keyword/1111303 true 1111303 true Keyword 1111304 /api/keyword/1111304 true 1111304 true Keyword 1111305 /api/keyword/1111305 true 1111305 true Keyword 1111306 /api/keyword/1111306 true 1111306 true MtaRating 10487092 /api/mtarating/10487092 RatingType 10026 /api/ratingtype/10026 PsziTB Institute 14108 /api/institute/14108 0 false true false Pszichológiai Tudományos Bizottság Committee on Psychology true 14108 true true true A true true MtaRating 11507998 /api/mtarating/11507998 RatingType 10011 /api/ratingtype/10011 DEM Institute 19060 /api/institute/19060 0 false true false Demográfiai Osztályközi Állandó Bizottság Committee on Demography true 19060 true true true A hazai false true SjrRating 6008617 /api/sjrrating/6008617 1811 0.74 journal RatingType 10002 /api/ratingtype/10002 sjr true true ClassificationExternal 2701 /api/classificationexternal/2701 true 2701 true Q3 DIRECT true 6008617 true /api/publication/1835872 <div class="JournalArticle Publication long-list"> <div class="authors"> <img title="Forrásközlemény" style="float: left" src="/frontend/resources/grid/publication-core-icon.png"> <div class="autype autype0"> <span class="author-name" mtid="10011064"><a href="/gui2/?type=authors&mode=browse&sel=10011064" target="_blank">Kerpel-Fronius S (<span class="authorship-author-name">Kerpel-Fronius Sándor</span> <span class="authorAux-mtmt"> Klinikai farmakológia</span>) </a> </span> <span class="author-affil"><span title="Semmelweis Egyetem">SE</span>/<span title="Általános Orvostudományi Kar">AOK</span>/<span title="Intézet">I</span>/Farmakológiai és Farmakoterápiás Intézet</span> </div> </div> <div class="title"><a href="/gui2/?mode=browse&params=publication;1835872" target="_blank">A hazai referencia gyógyszerárkeacute;pzés orvosszakmai problémái [Medical problems associated with the national reference pricing system in Hungary].</a></div> <div> <span class="journal-title">ORVOSI HETILAP</span> <span class="journal-issn">(<a target="_blank" href="https://portal.issn.org/resource/ISSN/0030-6002">0030-6002</a> <a target="_blank" href="https://portal.issn.org/resource/ISSN/1788-6120">1788-6120</a>)</span>: <span class="journal-volume">145</span> <span class="journal-issue">17</span> <span class="page"> pp 913-918 </span> <span class="year">(2004)</span> </div> <div class="pub-footer"> <span class="language" xmlns="http://www.w3.org/1999/html">Nyelv: Magyar | </span> <span class="identifiers"> <span class="id identifier oa_none" title="none"> <a style="color:blue" title="3042572883" target="_blank" href="http://www.scopus.com/record/display.url?origin=inward&eid=2-s2.0-3042572883"> Scopus </a> </span> <span class="id identifier oa_none" title="none"> <a style="color:blue" title="15170969" target="_blank" href="http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db=PubMed&list_uids=15170969&dopt=Abstract"> PubMed </a> </span> <span class="id identifier oa_none" title="none"> <a style="color:blue" title="73594" target="_blank" href="https://mob.aeek.hu/detailsperm.jsp?PERMID=73594"> MOB </a> </span> </span> <OnlyViewableByAuthor><div class="ratings"> <div class="journal-subject">Folyóirat szakterülete: Scopus - Medicine (miscellaneous)&nbsp;&nbsp;&nbsp;SJR indikátor:&nbsp;Q3</div> <div class="journal-subject">Pszichológiai Tudományos Bizottság II. FTO PsziTB [1901-]&nbsp;&nbsp;&nbsp;A</div> <div class="journal-subject">Demográfiai Osztályközi Állandó Bizottság IXGJO DEM [1901-]&nbsp;&nbsp;&nbsp;A hazai</div> </div></OnlyViewableByAuthor> <div class="publication-citation" style="margin-left: 0.5cm;"> <span title="Nyilvános idézőközlemények összesen, említések nélkül" class="citingPub-count">Nyilvános idéző összesen: 4</span> | Független: 4 | Függő: 0 | Nem jelölt: 0 | WoS jelölt: 4 | Scopus jelölt:&nbsp;4 | WoS/Scopus jelölt:&nbsp;4 | DOI jelölt:&nbsp;4 </div> <div class="mtid"><span class="long-pub-mtid">Közlemény: 1835872</span> | <span class="status-data status-VALIDATED"> Egyeztetett </span> <span class="oldId">Régi azonosító: 1835872</span> | Forrás | <span class="type-subtype">Folyóiratcikk ( Összefoglaló cikk ) </span> | <span class="pub-category">Tudományos</span> | <span class="publication-sourceOfData">MEDLINE</span> </div> <div class="lastModified">Utolsó módosítás: 2022.02.23. 19:06 Tichy Rita (SE_KK_Admin5_TR, admin) </div> </div></div>