https://m2.mtmt.hu/ eng 2026-10-24 11:39 JournalArticle 1826671 VALIDATED true Gergely Katona, Gergely Szalay, Pál Maák and Attila Kaszás: These authors contributed equally to this work. 0 2017-11-07T09:33:21.000+0000 false 1826671 2026-10-16T10:16:06.068+0000 2025-03-27T09:23:13.245+0000 2012-01-16T14:27:00.000+0000 true 10012926 Rózsa J. Balázs /api/author/10012926 Author true 10012926 2026-01-12T09:28:35.841+0000 2026-01-12T09:28:35.841+0000 2021-11-11T13:03:04.948+0000 true 10080102 Darabosné Maczkó Beáta /api/admin/10080102 Admin true Admin 10067876 /api/admin/10067876 Ladányi Gusztáv true true Admin 10080102 /api/admin/10080102 Darabosné Maczkó Beáta true true 2021-10-23T01:52:57.644+0000 true false true 24 24 /api/publicationtype/24 PublicationType 1 true 24 JournalArticle true 10000059 Article true 24 24 /api/publicationtype/24 PublicationType 1 true 24 JournalArticle /api/subtype/10000059 Szakcikk SubType 101 true 10000059 true 1 /api/category/1 Category true 1 Katona, G Fast two-photon in vivo imaging with three-dimensional random-access scanning in large tissue volumes true true /api/journal/10001306 REVIEWED true false 10001306 false 10001306 true 1548-7091 1548-7105 Journal FOREIGN 9 2 201 208 201 8 2012 The understanding of brain computations requires methods that read out neural activity on different spatial and temporal scales. Following signal propagation and integration across a neuron and recording the concerted activity of hundreds of neurons pose distinct challenges, and the design of imaging systems has been mostly focused on tackling one of the two operations. We developed a high-resolution, acousto-optic two-photon microscope with continuous three-dimensional (3D) trajectory and random-access scanning modes that reaches near-cubic-millimeter scan range and can be adapted to imaging different spatial scales. We performed 3D calcium imaging of action potential backpropagation and dendritic spike forward propagation at sub-millisecond temporal resolution in mouse brain slices. We also performed volumetric random-access scanning calcium imaging of spontaneous and visual stimulation-evoked activity in hundreds of neurons of the mouse visual cortex in vivo. These experiments demonstrate the subcellular and network-scale imaging capabilities of our system. 2012 319029 true true true false true false NONE 2026-10-16 false true 10014669 Szmolyán Mária /api/admin/10014669 Admin true 10014669 421 0 339 302 42 340 338 313 303 333 333 296 296 384 37 0 421 384 339 302 0 5 5 Folyóiratcikk Journal Article 24 302 Könyvrészlet Chapter in Book 25 32 Könyv Book 23 4 Egyéb konferenciaközlemény Conference paper 31 1 Egyéb konferenciakötet Conference proceedings 32 0 Oltalmi formák Protection forms 26 0 Disszertáció Thesis 28 63 Egyéb Miscellaneous 29 19 Alkotás Achievement 22 0 Kutatási adat Research data 33 0 Folyóiratcikk Journal Article 24 0 0 0 Könyvrészlet Chapter in Book 25 0 0 0 Könyv Book 23 0 0 0 Egyéb konferenciaközlemény Conference paper 31 0 0 0 Egyéb konferenciakötet Conference proceedings 32 0 0 0 Oltalmi formák Protection forms 26 0 0 0 Disszertáció Thesis 28 0 0 0 Egyéb Miscellaneous 29 0 0 0 Alkotás Achievement 22 0 0 0 Kutatási adat Research data 33 0 0 0 2012 0 9 8 9 8 2013 0 31 28 31 28 2014 0 24 22 24 22 2015 0 39 34 39 34 2016 0 32 28 32 28 2017 0 36 33 36 33 2018 0 32 30 32 30 2019 0 48 46 48 46 2020 0 39 37 39 37 2021 0 27 26 27 26 2022 0 26 24 26 24 2023 0 24 22 24 22 2024 0 29 25 29 25 2025 0 11 9 11 9 2026 0 14 12 14 12 D1 false 10054116,227,10046111,10017949 false false false 2017-11-07T09:33:21.000+0000 2012-11-10T10:48:55.000+0000 Atomfizika Tanszék (BME / TTK / FI); Farmakológiai Kutatócsoport (KOKI / GYO); Információs Technológiai Kar (PPKE); Két-foton Képalkotó Központ (KOKI / GYO) 10 44 4 10 0 true 10067876 10080102 Language 10002 /api/language/10002 Angol English true 2 true PersonAuthorship 2370014 /api/authorship/2370014 1 0.1 true false Author 191 /api/author/191 Katona Gergely true 191 true Katona G true false false AuthorshipType 1 /api/authorshiptype/1 0 true 0 true false 14245002 true PersonAuthorship 2370015 /api/authorship/2370015 2 0.1 true false Author 10054116 /api/author/10054116 Szalay Gergely true 10054116 true Szalay G true false false AuthorshipType 1 /api/authorshiptype/1 0 true 0 true false 14245001 true PersonAuthorship 2370016 /api/authorship/2370016 3 0.1 true false Author 10011238 /api/author/10011238 Maák Pál true 10011238 true Maak P true false false AuthorshipType 1 /api/authorshiptype/1 0 true 0 true false 14245000 true PersonAuthorship 2370017 /api/authorship/2370017 4 0.1 true false Author 227 /api/author/227 Kaszás Attila true 227 true Kaszas A true false false AuthorshipType 1 /api/authorshiptype/1 0 true 0 true false 14244999 true PersonAuthorship 2370018 /api/authorship/2370018 5 0.1 false false Author 10042301 /api/author/10042301 Veress Máté true 10042301 true Veress M true false false AuthorshipType 1 /api/authorshiptype/1 0 true 0 true false 14244998 true PersonAuthorship 2370019 /api/authorship/2370019 6 0.1 false false Author 10046111 /api/author/10046111 Hillier Dániel true 10046111 true Hillier D true false false AuthorshipType 1 /api/authorshiptype/1 0 true 0 true false 14244997 true PersonAuthorship 2370020 /api/authorship/2370020 7 0.1 false false Author 10017949 /api/author/10017949 Chiovini Balázs true 10017949 true Chiovini B true false false AuthorshipType 1 /api/authorshiptype/1 0 true 0 true false 14244996 true PersonAuthorship 2370021 /api/authorship/2370021 8 0.1 false false Author 10000023 /api/author/10000023 Vizi E. Szilveszter true 10000023 true Vizi ES true false false AuthorshipType 1 /api/authorshiptype/1 0 true 0 true false 14244995 true PersonAuthorship 2370022 /api/authorship/2370022 9 0.1 false false Author 10079728 /api/author/10079728 Roska Botond true true Roska B true false false AuthorshipType 1 /api/authorshiptype/1 0 true 0 true false 14244994 true PersonAuthorship 2370023 /api/authorship/2370023 10 0.1 false true true Author 10012926 /api/author/10012926 Rózsa J. Balázs true 10012926 true Rozsa B true false false AuthorshipType 1 /api/authorshiptype/1 0 true 0 true false 14244993 true PublicationIdentifier 469243 /api/publicationidentifier/469243 PlainSource 6 /api/publicationsource/6 PublicationSourceType 10001 /api/publicationsourcetype/10001 true true true DOI DOI https://doi.org/@@@ true true 6 true false IDENTICAL 10.1038/nmeth.1851 https://doi.org/10.1038/nmeth.1851 false 280034 true PublicationIdentifier 469241 /api/publicationidentifier/469241 PlainSource 1 /api/publicationsource/1 PublicationSourceType 10003 /api/publicationsourcetype/10003 false true true WoS WoS https://www.webofscience.com/wos/woscc/full-record/@@@ true true 1 true false IDENTICAL 000300029600034 https://www.webofscience.com/wos/woscc/full-record/000300029600034 false 611476 true PublicationIdentifier 469242 /api/publicationidentifier/469242 PlainSource 3 /api/publicationsource/3 PublicationSourceType 10003 /api/publicationsourcetype/10003 false true true Scopus Scopus http://www.scopus.com/record/display.url?origin=inward&eid=2-s2.0-@@@ true true 3 true false IDENTICAL 84856447940 http://www.scopus.com/record/display.url?origin=inward&eid=2-s2.0-84856447940 false 935972 true PublicationIdentifier 469244 /api/publicationidentifier/469244 PlainSource 17 /api/publicationsource/17 PublicationSourceType 10003 /api/publicationsourcetype/10003 false true true PubMed PubMed http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db=PubMed&list_uids=@@@&dopt=Abstract true true 17 true false IDENTICAL 22231641 http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db=PubMed&list_uids=22231641&dopt=Abstract false 280035 true Classification 10545 /api/classification/10545 true true SjrRating 5640352 /api/sjrrating/5640352 2 0.0 journal RatingType 10002 /api/ratingtype/10002 sjr true true ClassificationExternal 1305 /api/classificationexternal/1305 true 1305 true D1 DIRECT true 5640352 true /api/publication/1826671 <div class="JournalArticle Publication long-list"> <div class="authors"> <img title="Forrásközlemény" style="float: left" src="/frontend/resources/grid/publication-core-icon.png"> <img title="Idézőközlemény" style="float: left" src="/frontend/resources/grid/publication-citation-icon.png"> <div class="autype autype0"> <span class="author-name" mtid="191"><a href="/gui2/?type=authors&mode=browse&sel=191" target="_blank">Katona G (<span class="authorship-author-name">Katona Gergely</span> <span class="authorAux-mtmt"> Farmakológia</span>) </a> </span> ;&nbsp;&nbsp;&nbsp; <span class="author-name" mtid="10054116"><a href="/gui2/?type=authors&mode=browse&sel=10054116" target="_blank">Szalay G<sup>*</sup> (<span class="authorship-author-name">Szalay Gergely</span> <span class="authorAux-mtmt"> Idegtudomány</span>) </a> </span> <span class="author-affil"><span title="MTA Kísérleti Orvostudományi Kutatóintézet">IEMHAS</span>/<span title="Department of Pharmacology">DP</span>/Two-photon Imaging Center</span> ;&nbsp;&nbsp;&nbsp; <span class="author-name" mtid="10011238"><a href="/gui2/?type=authors&mode=browse&sel=10011238" target="_blank">Maak P<sup>*</sup> (<span class="authorship-author-name">Maák Pál</span> <span class="authorAux-mtmt"> Optika, lézerfizika</span>) </a> </span> <span class="author-affil"><span title="Budapest University of Technology and Economics">BUTE</span>/<span title="Faculty of Natural Sciences">FNS</span>/<span title="Institute of Physics">IP</span>/Department of Atomic Physics</span> ;&nbsp;&nbsp;&nbsp; <span class="author-name" mtid="227"><a href="/gui2/?type=authors&mode=browse&sel=227" target="_blank">Kaszas A<sup>*</sup> (<span class="authorship-author-name">Kaszás Attila</span> <span class="authorAux-mtmt"> Farmakológia</span>) </a> </span> <span class="author-affil"><span title="MTA Kísérleti Orvostudományi Kutatóintézet">IEMHAS</span>/<span title="Department of Pharmacology">DP</span>/Laboratory of Drug Research; <span title="Pázmány Péter Catholic University">PPCU</span>/Faculty of Information Technology</span> ;&nbsp;&nbsp;&nbsp; <span class="author-name" mtid="10042301"><a href="/gui2/?type=authors&mode=browse&sel=10042301" target="_blank">Veress M (<span class="authorship-author-name">Veress Máté</span> <span class="authorAux-mtmt"> atomfizika</span>) </a> </span> <span class="author-affil"><span title="Budapest University of Technology and Economics">BUTE</span>/<span title="Faculty of Natural Sciences">FNS</span>/<span title="Institute of Physics">IP</span>/Department of Atomic Physics</span> ;&nbsp;&nbsp;&nbsp; <span class="author-name" mtid="10046111"><a href="/gui2/?type=authors&mode=browse&sel=10046111" target="_blank">Hillier D (<span class="authorship-author-name">Hillier Dániel</span> <span class="authorAux-mtmt"> Idegtudomány, látórendszer, vizuális számítások...</span>) </a> </span> ;&nbsp;&nbsp;&nbsp; <span class="author-name" mtid="10017949"><a href="/gui2/?type=authors&mode=browse&sel=10017949" target="_blank">Chiovini B (<span class="authorship-author-name">Chiovini Balázs</span> <span class="authorAux-mtmt"> Neurobiológia</span>) </a> </span> <span class="author-affil"><span title="MTA Kísérleti Orvostudományi Kutatóintézet">IEMHAS</span>/<span title="Department of Pharmacology">DP</span>/Laboratory of Drug Research</span> ;&nbsp;&nbsp;&nbsp; <span class="author-name" mtid="10000023"><a href="/gui2/?type=authors&mode=browse&sel=10000023" target="_blank">Vizi ES (<span class="authorship-author-name">Vizi E. Szilveszter</span> <span class="authorAux-mtmt"> Neurofarmakológia, neurokémia</span>) </a> </span> <span class="author-affil"><span title="MTA Kísérleti Orvostudományi Kutatóintézet">IEMHAS</span>/<span title="Department of Pharmacology">DP</span>/Laboratory of Drug Research</span> ;&nbsp;&nbsp;&nbsp; <span class="author-name" mtid="10079728"><a href="/gui2/?type=authors&mode=browse&sel=10079728" target="_blank">Roska B (<span class="authorship-author-name">Roska Botond</span> <span class="authorAux-mtmt"> Neurobiológia</span>) </a> </span> ;&nbsp;&nbsp;&nbsp; <span class="author-name" mtid="10012926"><a href="/gui2/?type=authors&mode=browse&sel=10012926" target="_blank">Rozsa B ✉ (<span class="authorship-author-name">Rózsa J. Balázs</span> <span class="authorAux-mtmt"> Idegtudomány, fizika</span>) </a> </span> <span class="author-affil"><span title="Pázmány Péter Catholic University">PPCU</span>/Faculty of Information Technology; <span title="MTA Kísérleti Orvostudományi Kutatóintézet">IEMHAS</span>/<span title="Department of Pharmacology">DP</span>/Two-photon Imaging Center</span> </div> </div> <div class="title"><a href="/gui2/?mode=browse&params=publication;1826671" target="_blank">Fast two-photon in vivo imaging with three-dimensional random-access scanning in large tissue volumes</a></div> <div> <span class="journal-title">NATURE METHODS</span> <span class="journal-issn">(<a target="_blank" href="https://portal.issn.org/resource/ISSN/1548-7091">1548-7091</a> <a target="_blank" href="https://portal.issn.org/resource/ISSN/1548-7105">1548-7105</a>)</span>: <span class="journal-volume">9</span> <span class="journal-issue">2</span> <span class="page"> pp 201-208 </span> <span class="year">(2012)</span> </div> <div class="pub-footer"> <span class="language" xmlns="http://www.w3.org/1999/html">Language: English | </span> <span class="identifiers"> <span class="id identifier oa_none" title="none"> <a style="color:blue" title="10.1038/nmeth.1851" target="_blank" href="https://doi.org/10.1038/nmeth.1851"> DOI </a> </span> <span class="id identifier oa_none" title="none"> <a style="color:blue" title="000300029600034" target="_blank" href="https://www.webofscience.com/wos/woscc/full-record/000300029600034"> WoS </a> </span> <span class="id identifier oa_none" title="none"> <a style="color:blue" title="84856447940" target="_blank" href="http://www.scopus.com/record/display.url?origin=inward&eid=2-s2.0-84856447940"> Scopus </a> </span> <span class="id identifier oa_none" title="none"> <a style="color:blue" title="22231641" target="_blank" href="http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db=PubMed&list_uids=22231641&dopt=Abstract"> PubMed </a> </span> </span> <OnlyViewableByAuthor><div class="ratings"> <div class="journal-subject">Journal subject: Scopus - Biochemistry&nbsp;&nbsp;&nbsp;Rank:&nbsp;D1</div> <div class="journal-subject">Journal subject: Scopus - Biotechnology&nbsp;&nbsp;&nbsp;Rank:&nbsp;D1</div> <div class="journal-subject">Journal subject: Scopus - Cell Biology&nbsp;&nbsp;&nbsp;Rank:&nbsp;D1</div> <div class="journal-subject">Journal subject: Scopus - Molecular Biology&nbsp;&nbsp;&nbsp;Rank:&nbsp;D1</div> </div></OnlyViewableByAuthor> <div class="publication-citation" style="margin-left: 0.5cm;"> <span title="" class="citingPub-count">Citing papers: 421</span> | Independent citation: 384 | Self citation: 37 | Unknown citation: 0 | Number of citations in WoS: 313 | Number of citations in Scopus:&nbsp;303 | WoS/Scopus assigned:&nbsp;333 | Number of citations with DOI:&nbsp;338 </div> <div class="publication-citation"> <a target="_blank" href="/api/publication?cond=citations.related;eq;1826671&sort=publishedYear,desc&sort=title"> Number of cited publications: 5 </a> </div> <div class="mtid"><span class="long-pub-mtid">Publication: 1826671</span> | <span class="status-data status-VALIDATED"> Validated </span> <span class="oldId">Old id: 1826671</span> | Core Citing | <span class="type-subtype">Journal Article ( Article ) </span> | <span class="pub-category">Scientific</span> | <span class="publication-sourceOfData">MEDLINE</span> </div> <div class="lastModified">Last Modified: 2025.03.27. 10:23 Gusztáv Ladányi (MTMT API user, admin) </div> <div class="lockedBy">Centrally managed 2021.10.23. 03:52 Gusztáv Ladányi (MTMT API user, admin) Beáta Darabosné Maczkó (MTMT ellenőrzés admin5) </div> <pre class="comment" style="margin-top: 0; margin-bottom: 0;"><u>Comments</u>: Gergely Katona, Gergely Szalay, Pál Maák and Attila Kaszás: These authors contributed equally to this work.</pre> </div></div>