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The animals were treated once via the drinking water with 10 mg/kg of body-mass (after a previous water withdrawal). The experimental animals were exsanguinated 6, 24, 48, 72, 96, 120, 144, 192, as well as 240 hours after the treament and tissular samples were collected. Eggs of laying hens were collected during 14 days. ABZ content and concentration of its two metabolites (albendazole-sulfoxide = ABZ-SO, albendazole-sulfone = ABZ-SO2) were determined in the muscular, liver, skin + adipose tissular samples, as well as in the white and yolk of eggs by a HPLC method after acetonitrile extraction and Sep-Pak C18 purification. Based on the results obtained, it was found that total residual content of the tissues in broiler chickens was significantly high (muscle: 10 710 mu g/kg, liver 21 199 mu g/kg, skin and fat: 7716 mu g/kg) after 6 hours of treatment, however the mother molecule and its metabolites are eliminated quickly and none of the tissular samples contained metabolites above the detection limit value (muscle and skin + adipose tissue 10 mu g/kg, liver 50 mu g/kg) 96 hours after treatment (Tables 1 and 2, Figs 1 to 3). ABZ could not demonstrated in the eggs. Starting total concentration of metabolites was significantly lower than that of tissular samples (666.4 mu g/kg), however the elimination was slightly longer. 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