The Effect of Low-Level Laser in Knee Osteoarthritis: A Double-Blind, Randomized, Placebo-Controlled Trial

Hegedus, B [Hegedűs, Béla (Mozgásszervi reha...), szerző]; Viharos, L [Viharos, László (Valószínűségelmél...), szerző] Bolyai Intézet (Matematikai Tanszékcsoport) (SZTE / TTIK); Gervain, M; Galfi, M [Gálfi, Márta (Környezetbiológia), szerző] Környezet-biológia és Környezeti Nevelés Tanszék (SZTE / JGYPK / AEKNI)

Angol nyelvű Szakcikk (Folyóiratcikk) Tudományos
Megjelent: PHOTOMEDICINE AND LASER SURGERY 1549-5418 1557-8550 27 (4) pp. 577-584 2009
  • SJR Scopus - Biomedical Engineering: Q2
Azonosítók
Szakterületek:
  • Klinikai orvostan
  • Orvos- és egészségtudomány
  • Orvosi biotechnológia
  • Orvostechnikai műszaki tudományok
  • Tudomány
Introduction: Low-level laser therapy (LLLT) is thought to have an analgesic effect as well as a biomodulatory effect on microcirculation. This study was designed to examine the pain-relieving effect of LLLT and possible microcirculatory changes measured by thermography in patients with knee osteoarthritis (KOA). Materials and Methods: Patients with mild or moderate KOA were randomized to receive either LLLT or placebo LLLT. Treatments were delivered twice a week over a period of 4wk with a diode laser (wavelength 830 nm, continuous wave, power 50mW) in skin contact at a dose of 6 J/point. The placebo control group was treated with an ineffective probe (power 0.5mW) of the same appearance. Before examinations and immediately, 2 wk, and 2 mo after completing the therapy, thermography was performed (bilateral comparative thermograph by AGA infrared camera); joint flexion, circumference, and pressure sensitivity were measured; and the visual analogue scale was recorded. Results: In the group treated with active LLLT, a significant improvement was found in pain (before treatment [BT]: 5.75; 2 mo after treatment : 1.18); circumference (BT: 40.45; AT: 39.86); pressure sensitivity (BT: 2.33; AT: 0.77); and flexion (BT: 105.83; AT: 122.94). In the placebo group, changes in joint flexion and pain were not significant. Thermographic measurements showed at least a 0.5 degrees C increase in temperature-and thus an improvement in circulation compared to the initial values. In the placebo group, these changes did not occur. Conclusion: Our results show that LLLT reduces pain in KOA and improves microcirculation in the irradiated area.
Hivatkozás stílusok: IEEEACMAPAChicagoHarvardCSLMásolásNyomtatás
2026-10-09 09:54