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Besides the clinical\\nexamination, before the first treatment (baseline sample), and about 3\\nweeks later, 17 to 24 days following the last treatment (control\\nsample) milk samples were collected for bacteriological identification\\nof the mastitis pathogens and for the determination of certain\\ninflammatory markers: somatic cell count (SCC),\\nN-acetyl-beta-D-glucosaminidase (NAGase) and alpha(1)-antitrypsin (ATR)\\nactivities, as well as bovine serum albumin (BSA) and chloride (Cl-)\\nconcentrations. Based upon the clinical and bacteriological status as\\nwell as the SCC recorded at the control investigations, 6 groups were\\nestablished (recovered, latently infected; subclinical mastitis:\\nbacteriologically positive and negative, as well as clinical mastitis:\\nbacteriologically positive and negative). As compared to the baseline\\nsamples, all parameters decreased in the case of recovered udder\\nquarters, as well as in those with abated latent infection or\\nsubclinical mastitis at the time of control examination. Comparing the\\ncontrol samples of the different categories, characteristic differences\\nwere found in NAGase activity, indicating the grade of cytodamaging\\neffect of mastitis. Of the other markers, ATR and Cl- proved to be more\\nadequate for the differentiation than BSA. It can be concluded that, in\\naddition to SCC, first of all NAGase can be recommended for use as an\\ninflammatory parameter in pharmacodynamic studies. 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