European Community’s Seventh Framework Program(FP7/ 2007-2013 under Grant Agreement
245009)
Subjects:
Basic medicine
In this paper a modular model of the GnRH neuron is presented. For the aim of simplicity,
the currents corresponding to fast time scales and action potential generation are
described by an impulsive system, while the slower currents and calcium dynamics are
described by usual ordinary differential equations (ODEs). The model is able to reproduce
the depolarizing afterpotentials, afterhyperpolarization, periodic bursting behavior
and the corresponding calcium transients observed in the case of GnRH neurons.