Investigation of acidic pharmaceuticals in river water and sediment by microwave-assisted extraction and gas chromatography-mass spectrometry

Varga, M [Oltiné Varga, Margit (Víz-, és talajana...), szerző] Környezetkémiai és Bioanalitikai Laboratórium (... (ELTE / TTK / KI); Dobor, J [Dobor, József (környezettudomány...), szerző] Analitikai Kémiai Tanszék (ELTE / TTK / KI); Helenkar, A; Jurecska, L [Jurecska, Laura (környezetkémia), szerző]; Yao, J; Zaray, G [Záray, Gyula (Analitikai kémia,...), szerző] Környezetkémiai és Bioanalitikai Laboratórium (... (ELTE / TTK / KI)

Angol nyelvű Tudományos Szakcikk (Folyóiratcikk)
Megjelent: MICROCHEMICAL JOURNAL 0026-265X 95 (2) pp. 353-358 2010
  • SJR Scopus - Analytical Chemistry: Q2
    Investigations were performed along the Danube river at Budapest (Hungary) by collecting water and sediment samples simultaneously for 1 year in order to clarify the possible hazard of selected acidic pharmaceuticals (ibuprofen, naproxen, ketoprofen, and diclofenac) on the water supply used for the production of drinking water by bank filtration In the case of water samples, the sample preparation procedure included solid phase extraction (SPE). meanwhile, in the case of sediment samples, microwave-assisted extraction (MAE) followed by dispersive matrix extraction (DME) for pre-cleaning as well as SPE for enrichment The quantification was carried out using gas chromatography-mass spectrometry (GC-MS) The calculated recoveries were 97-99% (+/- 7%) for the water and 95-103% (+/- 12%) for the sediment samples In the river water, ketoprofen concentration was always below the limit of quantification (LOQ) level, ibuprofen, naproxen and diclofenac could be quantified in the range of 8-50, 2-30. 7-90 ng/L In sediments, only naproxen and diclofenac were found in the range of 2-20 and 5-38 ng/g, respectively According to the obtained results, the concentration ratios of the two phases linearly depended on the total organic carbon content (TOC) of the sediments at each sampling date The linear regressions were 0 925 and 0 946 for naproxen and diclofenac, respectively (C) 2010 Published by Elsevier B.V
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    2020-09-27 19:46