{ "labelLang" : "hun", "responseDate" : "2024-03-29 02:09", "content" : { "otype" : "JournalArticle", "mtid" : 1488623, "status" : "ADMIN_APPROVED", "published" : true, "comment" : "Cited By :12 \n Export Date: 20 February 2021 \n CODEN: APHGA \n Correspondence Address: Antal, I.; Gyogyszereszeti Intezet, Hogyes Endre u. 7, 1092 Budapest, Hungary", "unhandledTickets" : 0, "oldTimestamp" : "2014-08-14T20:02:00.000+0000", "deleted" : false, "oldId" : 1488623, "lastRefresh" : "2024-03-27T10:14:48.492+0000", "lastModified" : "2024-03-26T13:42:42.893+0000", "created" : "2011-03-29T11:20:08.000+0000", "creator" : { "otype" : "Author", "mtid" : 10020626, "link" : "/api/author/10020626", "label" : "Antal István (Gyógyszertechnológia)", "familyName" : "Antal", "givenName" : "István", "published" : true, "oldId" : 10020626, "snippet" : true }, "lastDuplumOK" : "2024-03-26T08:21:06.518+0000", "lastDuplumSearch" : "2024-03-26T08:21:06.518+0000", "adminApproved" : "2024-03-26T13:42:43.114+0000", "adminApprover" : { "otype" : "Admin", "mtid" : 10074913, "link" : "/api/admin/10074913", "label" : "Sághi-Keszthelyi Anna (SE_KK_Admin5_SKA, admin)", "familyName" : "Sághi-Keszthelyi", "givenName" : "Anna", "published" : true, "snippet" : true }, "core" : true, "citation" : true, "publicationPending" : false, "type" : { "otype" : "PublicationType", "mtid" : 24, "link" : "/api/publicationtype/24", "label" : "Folyóiratcikk", "code" : 24, "otypeName" : "JournalArticle", "listPosition" : 1, "published" : true, "oldId" : 24, "snippet" : true }, "subType" : { "otype" : "SubType", "mtid" : 1134514, "link" : "/api/subtype/1134514", "label" : "Összefoglaló cikk (Folyóiratcikk)", "name" : "Összefoglaló cikk", "nameEng" : "Survey paper", "docType" : { "otype" : "PublicationType", "mtid" : 24, "link" : "/api/publicationtype/24", "label" : "Folyóiratcikk", "code" : 24, "otypeName" : "JournalArticle", "listPosition" : 1, "published" : true, "oldId" : 24, "snippet" : true }, "listPosition" : 102, "published" : true, "oldId" : 1134514, "snippet" : true }, "category" : { "otype" : "Category", "mtid" : 1, "link" : "/api/category/1", "label" : "Tudományos", "published" : true, "oldId" : 1, "snippet" : true }, "languages" : [ { "otype" : "Language", "mtid" : 10001, "link" : "/api/language/10001", "label" : "Magyar", "name" : "Magyar", "nameEng" : "Hungarian", "published" : true, "oldId" : 1, "snippet" : true } ], "firstAuthor" : "Antal, I", "authorships" : [ { "otype" : "PersonAuthorship", "mtid" : 1460753, "link" : "/api/authorship/1460753", "label" : "Antal, I ✉ [Antal, István (Gyógyszertechnológia), szerző] Gyógyszerészeti Intézet (SE / GYTK)", "listPosition" : 1, "share" : 1.0, "first" : true, "last" : false, "corresponding" : true, "author" : { "otype" : "Author", "mtid" : 10020626, "link" : "/api/author/10020626", "label" : "Antal István (Gyógyszertechnológia)", "familyName" : "Antal", "givenName" : "István", "published" : true, "oldId" : 10020626, "snippet" : true }, "familyName" : "Antal", "givenName" : "I", "authorTyped" : true, "editorTyped" : false, "otherTyped" : false, "type" : { "otype" : "AuthorshipType", "mtid" : 1, "link" : "/api/authorshiptype/1", "label" : "Szerző", "code" : 0, "published" : true, "oldId" : 0, "snippet" : true }, "published" : false, "oldId" : 12008763, "snippet" : true } ], "title" : "A hatóanyag orális felszívódásának előrejelzésére alkalmazott kioldódás vizsgálatok biofarmáciai vonatkozásai", "identifiers" : [ { "otype" : "PublicationIdentifier", "mtid" : 358906, "link" : "/api/publicationidentifier/358906", "label" : "Scopus: 0035709866", "source" : { "otype" : "PlainSource", "mtid" : 3, "link" : "/api/publicationsource/3", "label" : "Scopus", "type" : { "otype" : "PublicationSourceType", "mtid" : 10003, "link" : "/api/publicationsourcetype/10003", "label" : "Indexelő adatbázis", "mayHaveOa" : false, "published" : true, "snippet" : true }, "name" : "Scopus", "linkPattern" : "http://www.scopus.com/record/display.url?origin=inward&eid=2-s2.0-@@@", "publiclyVisible" : true, "published" : true, "oldId" : 3, "snippet" : true }, "oaFree" : false, "validState" : "IDENTICAL", "idValue" : "0035709866", "realUrl" : "http://www.scopus.com/record/display.url?origin=inward&eid=2-s2.0-0035709866", "published" : false, "oldId" : 205215, "snippet" : true }, { "otype" : "PublicationIdentifier", "mtid" : 358907, "link" : "/api/publicationidentifier/358907", "label" : "PubMed: 11961894", "source" : { "otype" : "PlainSource", "mtid" : 17, "link" : "/api/publicationsource/17", "label" : "PubMed", "type" : { "otype" : "PublicationSourceType", "mtid" : 10003, "link" : "/api/publicationsourcetype/10003", "label" : "Indexelő adatbázis", "mayHaveOa" : false, "published" : true, "snippet" : true }, "name" : "PubMed", "nameEng" : "PubMed", "linkPattern" : "http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db=PubMed&list_uids=@@@&dopt=Abstract", "publiclyVisible" : true, "published" : true, "oldId" : 17, "snippet" : true }, "oaFree" : false, "validState" : "IDENTICAL", "idValue" : "11961894", "realUrl" : "http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db=PubMed&list_uids=11961894&dopt=Abstract", "published" : false, "oldId" : 205216, "snippet" : true } ], "journal" : { "otype" : "Journal", "mtid" : 1010825, "link" : "/api/journal/1010825", "label" : "ACTA PHARMACEUTICA HUNGARICA 0001-6659 1587-1495", "pIssn" : "0001-6659", "eIssn" : "1587-1495", "reviewType" : "REVIEWED", "noIF" : true, "sciIndexed" : false, "scopusIndexed" : true, "lang" : "FOREIGN_AND_HUNGARIAN", "hungarian" : true, "published" : true, "oldId" : 1010825, "snippet" : true }, "volume" : "71", "issue" : "3", "firstPage" : "280", "lastPage" : "288", "firstPageOrInternalIdForSort" : "280", "pageLength" : 9, "publishedYear" : 2001, "abstractText" : "Drug dissolution is a prerequisite to drug absorption and in vivo effectiveness for almost all drugs given in oral solid dosage forms. Drug absorption depends on the dissolution and solubilization of the drug under physiological conditions, and the permeability across the gastrointestinal tract. Because of the critical nature of the first steps, in vitro dissolution may be relevant to the prediction of biological response. Dissolution tests are applied to choose between formulation factors, assess the lot-to-lot quality of a drug product according to the biobatch; and ensure continuing product quality and performance after certain changes (e.g. in the formulation and manufacturing process, site of manufacture, scale-up). The recently developed Biopharmaceutical Classification System (BCS) has several benefits for recognizing how dissolution tests can be designed and which physiological factors have to be taken into consideration for the in vitro evaluation of solid dosage forms. Choice of test conditions (composition, volume and hydrodynamics of dissolution medium) should be based on where the drug is best absorbed in the gastrointestinal tract, and on whether it is administered in fasted or fed state. Duration of test and physiologically representative media can be selected to simulate gastric and intestinal environments according to the permeability profile of the drug, but mimicking in vivo hydrodynamics remains problematic and further research is required. To provide a basis for predicting the likelihood of achieving a successful in vivo-in vitro correlation, this review summarizes the biopharmaceutical considerations of in vivo drug relase in accordance with the BCS.", "subjects" : [ { "otype" : "Classification", "mtid" : 12125, "link" : "/api/classification/12125", "label" : "Általános orvostudomány", "published" : true, "snippet" : true }, { "otype" : "Classification", "mtid" : 12548, "link" : "/api/classification/12548", "label" : "Egyéb orvostudományok", "published" : true, "snippet" : true }, { "otype" : "Classification", "mtid" : 12215, "link" : "/api/classification/12215", "label" : "Klinikai orvostan", "published" : true, "snippet" : true } ], "keywords" : [ { "otype" : "Keyword", "mtid" : 65, "link" : "/api/keyword/65", "label" : "Humans", "published" : true, "oldId" : 65, "snippet" : true }, { "otype" : "Keyword", "mtid" : 1807, "link" : "/api/keyword/1807", "label" : "CIMETIDINE", "published" : true, "oldId" : 1807, "snippet" : true }, { "otype" : "Keyword", "mtid" : 1913, "link" : "/api/keyword/1913", "label" : "PARACETAMOL", "published" : true, "oldId" : 1913, "snippet" : true }, { "otype" : "Keyword", "mtid" : 3118, "link" : "/api/keyword/3118", "label" : "review", "published" : true, "oldId" : 3118, "snippet" : true }, { "otype" : "Keyword", "mtid" : 4024, "link" : "/api/keyword/4024", "label" : "Prognosis", "published" : true, "oldId" : 4024, "snippet" : true }, { "otype" : "Keyword", "mtid" : 5804, "link" : "/api/keyword/5804", "label" : "metoprolol", "published" : true, "oldId" : 5804, "snippet" : true }, { "otype" : "Keyword", "mtid" : 5837, "link" : "/api/keyword/5837", "label" : "carbamazepine", "published" : true, "oldId" : 5837, "snippet" : true }, { "otype" : "Keyword", "mtid" : 6586, "link" : "/api/keyword/6586", "label" : "in vitro study", "published" : true, "oldId" : 6586, "snippet" : true }, { "otype" : "Keyword", "mtid" : 6889, "link" : "/api/keyword/6889", "label" : "Administration, Oral", "published" : true, "oldId" : 6889, "snippet" : true }, { "otype" : "Keyword", "mtid" : 12368, "link" : "/api/keyword/12368", "label" : "quality control", "published" : true, "oldId" : 12368, "snippet" : true }, { "otype" : "Keyword", "mtid" : 13598, "link" : "/api/keyword/13598", "label" : "hydrodynamics", "published" : true, "oldId" : 13598, "snippet" : true }, { "otype" : "Keyword", "mtid" : 14135, "link" : "/api/keyword/14135", "label" : "drug formulation", "published" : true, "oldId" : 14135, "snippet" : true }, { "otype" : "Keyword", "mtid" : 14300, "link" : "/api/keyword/14300", "label" : "drug efficacy", "published" : true, "oldId" : 14300, "snippet" : true }, { "otype" : "Keyword", "mtid" : 14379, "link" : "/api/keyword/14379", "label" : "gastrointestinal tract", "published" : true, "oldId" : 14379, "snippet" : true }, { "otype" : "Keyword", "mtid" : 14710, "link" : "/api/keyword/14710", "label" : "Solutions", "published" : true, "oldId" : 14710, "snippet" : true }, { "otype" : "Keyword", "mtid" : 14738, "link" : "/api/keyword/14738", "label" : "drug solubility", "published" : true, "oldId" : 14738, "snippet" : true }, { "otype" : "Keyword", "mtid" : 14834, "link" : "/api/keyword/14834", "label" : "ranitidine", "published" : true, "oldId" : 14834, "snippet" : true }, { "otype" : "Keyword", "mtid" : 14998, "link" : "/api/keyword/14998", "label" : "in vivo study", "published" : true, "oldId" : 14998, "snippet" : true }, { "otype" : "Keyword", "mtid" : 15202, "link" : "/api/keyword/15202", "label" : "food intake", "published" : true, "oldId" : 15202, "snippet" : true }, { "otype" : "Keyword", "mtid" : 19880, "link" : "/api/keyword/19880", "label" : "furosemide", "published" : true, "oldId" : 19880, "snippet" : true }, { "otype" : "Keyword", "mtid" : 1009585, "link" : "/api/keyword/1009585", "label" : "drug absorption", "published" : true, "oldId" : 1009585, "snippet" : true }, { "otype" : "Keyword", "mtid" : 1010086, "link" : "/api/keyword/1010086", "label" : "Intestinal Absorption", "published" : true, "oldId" : 1010086, "snippet" : true }, { "otype" : "Keyword", "mtid" : 1011325, "link" : "/api/keyword/1011325", "label" : "Pharmaceutical Preparations", "published" : true, "oldId" : 1011325, "snippet" : true }, { "otype" : "Keyword", "mtid" : 1011542, "link" : "/api/keyword/1011542", "label" : "drug penetration", "published" : true, "oldId" : 1011542, "snippet" : true }, { "otype" : "Keyword", "mtid" : 1012952, "link" : "/api/keyword/1012952", "label" : "Griseofulvin", "published" : true, "oldId" : 1012952, "snippet" : true }, { "otype" : "Keyword", "mtid" : 1012955, "link" : "/api/keyword/1012955", "label" : "drug dosage form", "published" : true, "oldId" : 1012955, "snippet" : true }, { "otype" : "Keyword", "mtid" : 1013037, "link" : "/api/keyword/1013037", "label" : "Drug release", "published" : true, "oldId" : 1013037, "snippet" : true }, { "otype" : "Keyword", "mtid" : 1034397, "link" : "/api/keyword/1034397", "label" : "theophylline", "published" : true, "oldId" : 1034397, "snippet" : true }, { "otype" : "Keyword", "mtid" : 1036570, "link" : "/api/keyword/1036570", "label" : "Ketoconazole", "published" : true, "oldId" : 1036570, "snippet" : true }, { "otype" : "Keyword", "mtid" : 1041846, "link" : "/api/keyword/1041846", "label" : "drug manufacture", "published" : true, "oldId" : 1041846, "snippet" : true }, { "otype" : "Keyword", "mtid" : 1042937, "link" : "/api/keyword/1042937", "label" : "atenolol", "published" : true, "oldId" : 1042937, "snippet" : true }, { "otype" : "Keyword", "mtid" : 1043209, "link" : "/api/keyword/1043209", "label" : "hydrochlorothiazide", "published" : true, "oldId" : 1043209, "snippet" : true } ], "digital" : null, "printed" : null, "sourceYear" : 2011, "foreignEdition" : false, "foreignLanguage" : false, "fullPublication" : true, "conferencePublication" : false, "nationalOrigin" : true, "missingAuthor" : false, "oaType" : "NONE", "oaCheckDate" : "2024-03-27", "oaFree" : false, "citationCount" : 12, "citationCountUnpublished" : 0, "citationCountWoOther" : 12, "independentCitCountWoOther" : 7, "nationalOriginCitationCount" : 10, "foreignEditionCitationCount" : 5, "doiCitationCount" : 1, "wosCitationCount" : 4, "scopusCitationCount" : 12, "wosScopusCitationCount" : 12, "wosScopusCitationCountWoOther" : 12, "wosScopusIndependentCitationCount" : 7, "wosScopusIndependentCitationCountWoOther" : 7, "independentCitationCount" : 7, "selfCitationCount" : 5, "unhandledCitationCount" : 0, "citingPubCount" : 12, "independentCitingPubCount" : 7, "citingPubCountWoOther" : 12, "independentCitingPubCountWoOther" : 7, "unhandledCitingPubCount" : 0, "citedPubCount" : 2, "citedCount" : 2, "pubStats" : { "types" : [ { "type" : "Folyóiratcikk", "typeEng" : "Journal Article", "code" : 24, "count" : 12 }, { "type" : "Könyvrészlet", "typeEng" : "Chapter in Book", "code" : 25, "count" : 0 }, { "type" : "Könyv", "typeEng" : "Book", "code" : 23, "count" : 0 }, { "type" : "Egyéb konferenciaközlemény", "typeEng" : "Conference paper", "code" : 31, "count" : 0 }, { "type" : "Egyéb konferenciakötet", "typeEng" : "Conference proceedings", "code" : 32, "count" : 0 }, { "type" : "Oltalmi formák", "typeEng" : "Protection forms", "code" : 26, "count" : 0 }, { "type" : "Disszertáció", "typeEng" : "Thesis", "code" : 28, "count" : 0 }, { "type" : "Egyéb", "typeEng" : "Miscellaneous", "code" : 29, "count" : 0 }, { "type" : "Alkotás", "typeEng" : "Achievement", "code" : 22, "count" : 0 }, { "type" : "Kutatási adat", "typeEng" : "Research data", "code" : 33, "count" : 0 } ], "citationTypes" : [ { "type" : "Folyóiratcikk", "typeEng" : "Journal Article", "code" : 24, "countUnknown" : 0, "countIndependent" : 0, "countSelfCitation" : 0 }, { "type" : "Könyvrészlet", "typeEng" : "Chapter in Book", "code" : 25, "countUnknown" : 0, "countIndependent" : 0, "countSelfCitation" : 0 }, { "type" : "Könyv", "typeEng" : "Book", "code" : 23, "countUnknown" : 0, "countIndependent" : 0, "countSelfCitation" : 0 }, { "type" : "Egyéb konferenciaközlemény", "typeEng" : "Conference paper", "code" : 31, "countUnknown" : 0, "countIndependent" : 0, "countSelfCitation" : 0 }, { "type" : "Egyéb konferenciakötet", "typeEng" : "Conference proceedings", "code" : 32, "countUnknown" : 0, "countIndependent" : 0, "countSelfCitation" : 0 }, { "type" : "Oltalmi formák", "typeEng" : "Protection forms", "code" : 26, "countUnknown" : 0, "countIndependent" : 0, "countSelfCitation" : 0 }, { "type" : "Disszertáció", "typeEng" : "Thesis", "code" : 28, "countUnknown" : 0, "countIndependent" : 0, "countSelfCitation" : 0 }, { "type" : "Egyéb", "typeEng" : "Miscellaneous", "code" : 29, "countUnknown" : 0, "countIndependent" : 0, "countSelfCitation" : 0 }, { "type" : "Alkotás", "typeEng" : "Achievement", "code" : 22, "countUnknown" : 0, "countIndependent" : 0, "countSelfCitation" : 0 }, { "type" : "Kutatási adat", "typeEng" : "Research data", "code" : 33, "countUnknown" : 0, "countIndependent" : 0, "countSelfCitation" : 0 } ], "years" : [ { "year" : 2002, "publicationCount" : 0, "citationCount" : 1, "independentCitationCount" : 0, "citingPubCount" : 1, "independentCitingPubCount" : 0, "oaStats" : null, "oaStats2" : null }, { "year" : 2003, "publicationCount" : 0, "citationCount" : 0, "independentCitationCount" : 0, "citingPubCount" : 0, "independentCitingPubCount" : 0, "oaStats" : null, "oaStats2" : null }, { "year" : 2004, "publicationCount" : 0, "citationCount" : 3, "independentCitationCount" : 3, "citingPubCount" : 3, "independentCitingPubCount" : 3, "oaStats" : null, "oaStats2" : null }, { "year" : 2005, "publicationCount" : 0, "citationCount" : 4, "independentCitationCount" : 3, "citingPubCount" : 4, "independentCitingPubCount" : 3, "oaStats" : null, "oaStats2" : null }, { "year" : 2006, "publicationCount" : 0, "citationCount" : 1, "independentCitationCount" : 0, "citingPubCount" : 1, "independentCitingPubCount" : 0, "oaStats" : null, "oaStats2" : null }, { "year" : 2007, "publicationCount" : 0, "citationCount" : 1, "independentCitationCount" : 0, "citingPubCount" : 1, "independentCitingPubCount" : 0, "oaStats" : null, "oaStats2" : null }, { "year" : 2008, "publicationCount" : 0, "citationCount" : 1, "independentCitationCount" : 0, "citingPubCount" : 1, "independentCitingPubCount" : 0, "oaStats" : null, "oaStats2" : null }, { "year" : 2009, "publicationCount" : 0, "citationCount" : 0, "independentCitationCount" : 0, "citingPubCount" : 0, "independentCitingPubCount" : 0, "oaStats" : null, "oaStats2" : null }, { "year" : 2010, "publicationCount" : 0, "citationCount" : 0, "independentCitationCount" : 0, "citingPubCount" : 0, "independentCitingPubCount" : 0, "oaStats" : null, "oaStats2" : null }, { "year" : 2011, "publicationCount" : 0, "citationCount" : 1, "independentCitationCount" : 1, "citingPubCount" : 1, "independentCitingPubCount" : 1, "oaStats" : null, "oaStats2" : null } ] }, "ratings" : [ { "otype" : "SjrRating", "mtid" : 6113132, "link" : "/api/sjrrating/6113132", "label" : "sjr:Q3 (2001) Scopus - Medicine (miscellaneous) ACTA PHARMACEUTICA HUNGARICA 0001-6659", "listPos" : 1571, "rankValue" : 0.74, "type" : "journal", "ratingType" : { "otype" : "RatingType", "mtid" : 10002, "link" : "/api/ratingtype/10002", "label" : "sjr", "code" : "sjr", "published" : true, "snippet" : true }, "subject" : { "otype" : "ClassificationExternal", "mtid" : 2701, "link" : "/api/classificationexternal/2701", "label" : "Scopus - Medicine (miscellaneous)", "published" : true, "oldId" : 2701, "snippet" : true }, "ranking" : "Q3", "calculation" : "DIRECT", "published" : true, "oldId" : 6113132, "snippet" : true } ], "ratingsForSort" : "Q3", "references" : [ { "otype" : "Reference", "mtid" : 1248100, "link" : "/api/reference/1248100", "label" : "1. (1997) Extended Release Solid Oral Dosage Forms: Development, Evaluation, and Application of In Vitro/In Vivo Correlations, , Center for Drug Evaluation and Research, Food and Drug Administration, September", "listPosition" : 1, "published" : false, "snippet" : true }, { "otype" : "Reference", "mtid" : 1248101, "link" : "/api/reference/1248101", "label" : "2. Polli, J.E., Crison, J.R., Amidon, G.L., (1996) J. Pharm. Sci., 85, pp. 753-760", "listPosition" : 2, "published" : false, "snippet" : true }, { "otype" : "Reference", "mtid" : 1248102, "link" : "/api/reference/1248102", "label" : "3. Galia, E., Nicolaides, E., Horter, D., Lobenberg, R., Reppas, C., Dressman, J.B., (1998) Pharm. Res., 15, pp. 698-705", "listPosition" : 3, "published" : false, "snippet" : true }, { "otype" : "Reference", "mtid" : 1248103, "link" : "/api/reference/1248103", "label" : "4. Note for Guidance on Development Pharmaceutics, , Committee for Proprietary Medicinal Products, 155/96, EMEA", "listPosition" : 4, "published" : false, "snippet" : true }, { "otype" : "Reference", "mtid" : 1248104, "link" : "/api/reference/1248104", "label" : "5. Note for Guidance on the Investigation of Bioavailability and Bioequivalence, , Committee for Proprietary Medicinal Products, 1401/98, EMEA", "listPosition" : 5, "published" : false, "snippet" : true }, { "otype" : "Reference", "mtid" : 1248105, "link" : "/api/reference/1248105", "label" : "6. (1991) Note for Guidance: Investigation of Bioavailability and Bioequivalence, , Directive 65/65/EEC, Annex to Directive 75/318/EEC, December", "listPosition" : 6, "published" : false, "snippet" : true }, { "otype" : "Reference", "mtid" : 1248106, "link" : "/api/reference/1248106", "label" : "7. (1990) Note for Guidance: Clinical Testing of Prolonged Action Forms with Special Reference to Extended Release Forms, , Annex to Directive 75/318/EEC, July", "listPosition" : 7, "published" : false, "snippet" : true }, { "otype" : "Reference", "mtid" : 1248107, "link" : "/api/reference/1248107", "label" : "8. Carstensen, J., Theory of dosage forms dissolution (1982) Proc. 2nd Wisconsin Update Conference-Dissolution-State of the Art", "listPosition" : 8, "published" : false, "snippet" : true }, { "otype" : "Reference", "mtid" : 1248108, "link" : "/api/reference/1248108", "label" : "9. Makoid, M.C., Dufour, A., Banakar, U.V., Modelling of dissolution behaviour of controlled release systems (1993) STP Pharma Pratiques, 3 (1), pp. 49-58", "listPosition" : 9, "published" : false, "snippet" : true }, { "otype" : "Reference", "mtid" : 1248109, "link" : "/api/reference/1248109", "label" : "10. Rácz-Selmeczi, Gyógyszertechnológia I-III (2001) Medicina Könyvkiadö, , Budapest", "listPosition" : 10, "published" : false, "snippet" : true }, { "otype" : "Reference", "mtid" : 1248110, "link" : "/api/reference/1248110", "label" : "11. Blume, H., Gunder-Remy, U., Möller, H., (1991) Controlled/Modified Release Products, , Wissenschaft. Verlagsges. mbH, Stuttgart", "listPosition" : 11, "published" : false, "snippet" : true }, { "otype" : "Reference", "mtid" : 1248111, "link" : "/api/reference/1248111", "label" : "12. Dredán, J., Antal, I., Rácz, I., (1996) Int. J. Pharm., 145, pp. 61-64", "listPosition" : 12, "published" : false, "snippet" : true }, { "otype" : "Reference", "mtid" : 1248112, "link" : "/api/reference/1248112", "label" : "13. Macheras, P., Dokoumetzidis, A., (2000) Pharm. Res., 17, pp. 108-112", "listPosition" : 13, "published" : false, "snippet" : true }, { "otype" : "Reference", "mtid" : 1248113, "link" : "/api/reference/1248113", "label" : "14. Csóka, G., Dredán, J., Marton, S., Antal, I., Rácz, I., (1999) Pharm. Dev. Technol., 4 (2), pp. 291-294", "listPosition" : 14, "published" : false, "snippet" : true }, { "otype" : "Reference", "mtid" : 1248114, "link" : "/api/reference/1248114", "label" : "15. (1999) Note for Guidance on Quality of Modified Released Products, , Committee for Proprietary Medicinal Products, 604/96, EMEA, July", "listPosition" : 15, "published" : false, "snippet" : true }, { "otype" : "Reference", "mtid" : 1248115, "link" : "/api/reference/1248115", "label" : "16. (1990) Note for Guidance: Clinical Testing of Prolonged Action Forms with Special Reference to Extended Release Forms, , Annex to Directive 75/318/EEC, July", "listPosition" : 16, "published" : false, "snippet" : true }, { "otype" : "Reference", "mtid" : 1248116, "link" : "/api/reference/1248116", "label" : "17. (2000) Guidance for Industry: Waiver of In Vivo Bioavailability and Bioequivalence Studies for Immediate-Release Solid Oral Dosage Forms Based on a Biopharmaceutics Classification System, , FDA, Center for Drug Evaluation and Research August", "listPosition" : 17, "published" : false, "snippet" : true }, { "otype" : "Reference", "mtid" : 1248117, "link" : "/api/reference/1248117", "label" : "18. (1997) Ph.Eur. 3rd. Ed.", "listPosition" : 18, "published" : false, "snippet" : true }, { "otype" : "Reference", "mtid" : 1248118, "link" : "/api/reference/1248118", "label" : "19. (1997) Guidance for Industry, SUPAC-MR: Modified Release Solid Oral Dosage Forms, , FDA, Center for Drug Evaluation and Research, September", "listPosition" : 19, "published" : false, "snippet" : true }, { "otype" : "Reference", "mtid" : 1248119, "link" : "/api/reference/1248119", "label" : "20. Standard terms: Pharmaceutical dosage forms (2000) Pharmeuropa, (SPEC. ISSUE). , January", "listPosition" : 20, "published" : false, "snippet" : true }, { "otype" : "Reference", "mtid" : 1248120, "link" : "/api/reference/1248120", "label" : "21. (1992) Note for Guidance: Quality of Prolonged Release Oral Solid Dosage Forms, , Annex to Directive 75/318/EEC, October", "listPosition" : 21, "published" : false, "snippet" : true }, { "otype" : "Reference", "mtid" : 1248121, "link" : "/api/reference/1248121", "label" : "22. (2000) Ph.Eur. 3rd. Ed., (SUPPL.), p. 1357", "listPosition" : 22, "published" : false, "snippet" : true }, { "otype" : "Reference", "mtid" : 1248122, "link" : "/api/reference/1248122", "label" : "23. Dressman, J.B., Amidon, G.L., Reppas, C., Shah, V.P., (1998) Pharm. Res., 15, pp. 11-22", "listPosition" : 23, "published" : false, "snippet" : true }, { "otype" : "Reference", "mtid" : 1248123, "link" : "/api/reference/1248123", "label" : "24. Stricker, H., (1969) Pharm. Ind., 31, p. 794", "listPosition" : 24, "published" : false, "snippet" : true }, { "otype" : "Reference", "mtid" : 1248124, "link" : "/api/reference/1248124", "label" : "25. Stricker, H., (1971) Pharm. Ind., 33 (157), p. 446", "listPosition" : 25, "published" : false, "snippet" : true }, { "otype" : "Reference", "mtid" : 1248125, "link" : "/api/reference/1248125", "label" : "26. Yau, M.K.T., Meyer, M.C., (1981) J. Pharm. Sci., 70, p. 1017", "listPosition" : 26, "published" : false, "snippet" : true }, { "otype" : "Reference", "mtid" : 1248126, "link" : "/api/reference/1248126", "label" : "27. Brockmeier, D., Voegele, D., Hattingberg, H.M., (1983) Arzneim.-Forsch./Dug Res., 33 (1), pp. 598-601", "listPosition" : 27, "published" : false, "snippet" : true }, { "otype" : "Reference", "mtid" : 1248127, "link" : "/api/reference/1248127", "label" : "28. Szentmiklósi, P., Marton, S., Hajdú, M., (1986) Gyógyszerészet, 30, pp. 289-294", "listPosition" : 28, "published" : false, "snippet" : true }, { "otype" : "Reference", "mtid" : 1248128, "link" : "/api/reference/1248128", "label" : "29. Amidon, G.L., Lennernas, H., Shah, V.P., Crison, J.R., (1995) Pharm. Res., 12, pp. 413-420", "listPosition" : 29, "published" : false, "snippet" : true }, { "otype" : "Reference", "mtid" : 1248129, "link" : "/api/reference/1248129", "label" : "30. Shargel, L., Yu, A., (1999) Applied Biopharmaceutics and Pharmacokinetics. 4th Ed., , McGraw, Hill MPD", "listPosition" : 30, "published" : false, "snippet" : true }, { "otype" : "Reference", "mtid" : 1248130, "link" : "/api/reference/1248130", "label" : "31. Gröning, V.R., (1984) Pharm. Ind., 46, p. 88", "listPosition" : 31, "published" : false, "snippet" : true }, { "otype" : "Reference", "mtid" : 1248131, "link" : "/api/reference/1248131", "label" : "32. Dressmann, J.B., Fleisher, D., (1986) J. Pharm. Sci., 75, pp. 109-116", "listPosition" : 32, "published" : false, "snippet" : true }, { "otype" : "Reference", "mtid" : 1248132, "link" : "/api/reference/1248132", "label" : "33. Dressman, J.B., Butler, J., Hempenstall, J., Reppas, C., (2001) Pharm. Tech., 6, pp. 68-76", "listPosition" : 33, "published" : false, "snippet" : true }, { "otype" : "Reference", "mtid" : 1248133, "link" : "/api/reference/1248133", "label" : "34. Lennernas, H., (1992) Pharm. Res., 9, pp. 1243-1255", "listPosition" : 34, "published" : false, "snippet" : true }, { "otype" : "Reference", "mtid" : 1248134, "link" : "/api/reference/1248134", "label" : "35. (1997) Guidance for Industry: Dissolution Testing of Immediate Release Solid Oral Dosage Forms, , FDA, Center for Drug Evaluation and Research, August", "listPosition" : 35, "published" : false, "snippet" : true }, { "otype" : "Reference", "mtid" : 1248135, "link" : "/api/reference/1248135", "label" : "36. Corrigan, O.I., (1997) Adv. Exp. Med. Biol., 423, pp. 111-128", "listPosition" : 36, "published" : false, "snippet" : true }, { "otype" : "Reference", "mtid" : 1248136, "link" : "/api/reference/1248136", "label" : "37. Grattan, T., (2000) Eur. J. Pharm. Biopharm., 49 (3), pp. 225-229", "listPosition" : 37, "published" : false, "snippet" : true }, { "otype" : "Reference", "mtid" : 1248137, "link" : "/api/reference/1248137", "label" : "38. Adkin, D.A., (1995) J. Pharm. Sci., 84 (12), pp. 1405-1409", "listPosition" : 38, "published" : false, "snippet" : true }, { "otype" : "Reference", "mtid" : 1248138, "link" : "/api/reference/1248138", "label" : "39. Noyes, A.A., Whitney, W.R., (1897) J. Amer. Chem. Soc., 19, pp. 930-934", "listPosition" : 39, "published" : false, "snippet" : true }, { "otype" : "Reference", "mtid" : 1248139, "link" : "/api/reference/1248139", "label" : "40. Nernst, W., Brunner, E., (1904) Z. Physik Chem., 47, pp. 52-110", "listPosition" : 40, "published" : false, "snippet" : true }, { "otype" : "Reference", "mtid" : 1248140, "link" : "/api/reference/1248140", "label" : "41. FIP guidelines for dissolution. Testing of solid oral products (1996) Drug Inf. J., 30, pp. 1071-1084", "listPosition" : 41, "published" : false, "snippet" : true }, { "otype" : "Reference", "mtid" : 1248141, "link" : "/api/reference/1248141", "label" : "42. Nikolics, K., (1973) Szerves vegyületek krisztallográfiai vizsgálata, , Akadémiai Kiadó, Budapest", "listPosition" : 42, "published" : false, "snippet" : true }, { "otype" : "Reference", "mtid" : 1248142, "link" : "/api/reference/1248142", "label" : "43. Dressmann, J.B., Reppas, C., (2000) Eur. J. Pharm. Sci., 12, pp. S573-S580", "listPosition" : 43, "published" : false, "snippet" : true }, { "otype" : "Reference", "mtid" : 1248143, "link" : "/api/reference/1248143", "label" : "44. Dressmann, J.B., (1990) Pharm. Res., 7, pp. 756-761", "listPosition" : 44, "published" : false, "snippet" : true }, { "otype" : "Reference", "mtid" : 1248144, "link" : "/api/reference/1248144", "label" : "45. Gray, V., Dressmann, J.B., (1996) Pharmacopeial Forum, 22, pp. 1943-1945", "listPosition" : 45, "published" : false, "snippet" : true }, { "otype" : "Reference", "mtid" : 1248145, "link" : "/api/reference/1248145", "label" : "46. Uch, A.S., Dressmann, J.B., (1996) Formulation of PoorlyAvailable Drugs for Oral Administration (Minutes of the European Symposium), , Editions de Sante, Paris", "listPosition" : 46, "published" : false, "snippet" : true }, { "otype" : "Reference", "mtid" : 1248146, "link" : "/api/reference/1248146", "label" : "47. Bronsted, H., Kopecek, J., (1992) Pharm. Res., 9, pp. 1540-1545", "listPosition" : 47, "published" : false, "snippet" : true }, { "otype" : "Reference", "mtid" : 1248147, "link" : "/api/reference/1248147", "label" : "48. Fordtran, J.S., Lochlear, T., (1966) Amer. J. Dig. Dis., 11, pp. 503-521", "listPosition" : 48, "published" : false, "snippet" : true }, { "otype" : "Reference", "mtid" : 1248148, "link" : "/api/reference/1248148", "label" : "49. FIP guidelines for dissolution testing of solid oral products (1981) Pharm. Ind., 43, pp. 334-343", "listPosition" : 49, "published" : false, "snippet" : true }, { "otype" : "Reference", "mtid" : 1248149, "link" : "/api/reference/1248149", "label" : "50. (1995) 〈1088〉 In vitro and in vivo evaluation of dosage forms, 23. , USP", "listPosition" : 50, "published" : false, "snippet" : true }, { "otype" : "Reference", "mtid" : 1248150, "link" : "/api/reference/1248150", "label" : "51. Kaus, L.C., Gillespie, W.R., Hussain, A.S., Amidon, G.A., (1999) Pharm. Res., 16, pp. 272-280", "listPosition" : 51, "published" : false, "snippet" : true }, { "otype" : "Reference", "mtid" : 1248151, "link" : "/api/reference/1248151", "label" : "52. Moore, J.G., Chistian, P.E., Coleman, R.E., (1981) Dig. Dis. Sci., 26, pp. 16-22", "listPosition" : 52, "published" : false, "snippet" : true }, { "otype" : "Reference", "mtid" : 1248152, "link" : "/api/reference/1248152", "label" : "53. Meyer, J.H., Elashoff, J., Porter-Fink, V., Dressmann, J.B., Amidon, G.L., (1988) Gastroenterology, 94, pp. 1315-1325", "listPosition" : 53, "published" : false, "snippet" : true }, { "otype" : "Reference", "mtid" : 1248153, "link" : "/api/reference/1248153", "label" : "54. Brener, W., Hendrix, T.R., McHugh, P.R., (1983) Gastroenterology, 85, pp. 76-82", "listPosition" : 54, "published" : false, "snippet" : true }, { "otype" : "Reference", "mtid" : 1248154, "link" : "/api/reference/1248154", "label" : "55. Kerlin, P., Zinsmeister, A., Phillips, S., (1982) Gastrenterology, 83, pp. 701-706", "listPosition" : 55, "published" : false, "snippet" : true }, { "otype" : "Reference", "mtid" : 1248155, "link" : "/api/reference/1248155", "label" : "56. Hoelzel, F., (1930) Amer. J. Physiol., 92, pp. 466-497", "listPosition" : 56, "published" : false, "snippet" : true }, { "otype" : "Reference", "mtid" : 1248156, "link" : "/api/reference/1248156", "label" : "57. John, V.A., Shotton, P.A., Moppert, J., Theobold, W., (1985) Brit. J. Clin. Pharmacol., 19, pp. 203S-206S", "listPosition" : 57, "published" : false, "snippet" : true }, { "otype" : "Reference", "mtid" : 1248157, "link" : "/api/reference/1248157", "label" : "58. Malagelada, J.R., (1984) Gastroenterology, 87, pp. 1255-1263", "listPosition" : 58, "published" : false, "snippet" : true }, { "otype" : "Reference", "mtid" : 1248158, "link" : "/api/reference/1248158", "label" : "59. Davis, S.S., Hardy, J.G., Fara, J.W., (1986) Gut, 27, pp. 886-892", "listPosition" : 59, "published" : false, "snippet" : true }, { "otype" : "Reference", "mtid" : 1248159, "link" : "/api/reference/1248159", "label" : "60. Wiggins, H.S., Cummings, J.H., (1976) Gut, 17, pp. 1007-1011", "listPosition" : 60, "published" : false, "snippet" : true }, { "otype" : "Reference", "mtid" : 1248160, "link" : "/api/reference/1248160", "label" : "61. Wilson, C.G., Washington, N., (1989) Physiological Pharmaceutics-Biological Barriers to Drug Absorption, , Chapter 6, Ellis Harwood Series in Pharmaceutical Technology, Chichester, UK", "listPosition" : 61, "published" : false, "snippet" : true } ], "hasCitationDuplums" : false, "userChangeableUntil" : "2014-02-19T17:37:59.000+0000", "publishDate" : "2013-02-23T19:18:00.000+0000", "directInstitutesForSort" : "Gyógyszerészeti Intézet (SE / GYTK)", "ownerAuthorCount" : 1, "ownerInstituteCount" : 3, "directInstituteCount" : 1, "authorCount" : 1, "contributorCount" : 0, "hasQualityFactor" : false, "link" : "/api/publication/1488623", "label" : "Antal I. A hatóanyag orális felszívódásának előrejelzésére alkalmazott kioldódás vizsgálatok biofarmáciai vonatkozásai. (2001) ACTA PHARMACEUTICA HUNGARICA 0001-6659 1587-1495 71 3 280-288", "template" : "