Lighting the chandelier: new vistas for axo-axonic cells

Howard, A; Tamas, G [Tamás, Gábor (Neurobiológia), szerző] MTA-SZTE Agykérgi Neuronhálózatok Kutatócsoport (SZTE / TTIK / BI / ÉSZIT); Soltesz, I [Soltesz, Ivan (Neurobiologia), szerző]

Angol nyelvű Tudományos Összefoglaló cikk (Folyóiratcikk)
Megjelent: TRENDS IN NEUROSCIENCES 0166-2236 28 (6) pp. 310-316 2005
Konferencia: INMED/TINS special issue: Multiple facets of GABAergic synapses
  • SJR Scopus - Neuroscience (miscellaneous): D1
Azonosítók
Szakterületek:
    Chandelier or axo-axonic cells are the most selective of all cortical GABAergic interneurons, because they exclusively contact axon initial segments of cortical glutamatergic neurons. Owing to their privileged location on initial segments, axo-axonic cells have often been assumed to have the ultimate control of pyramidal cell output. Recently, key molecules expressed at the initial-segment synapses have been identified, and novel in vitro and in vivo electrophysiological studies have revealed unexpectedly versatile functional effects exerted by axo-axonic cells on their postsynaptic targets. In addition, there is also emerging recognition of the mechanistic involvement of these unique cells in several neurological diseases, including epilepsy and schizophrenia.
    Hivatkozás stílusok: IEEEACMAPAChicagoHarvardCSLMásolásNyomtatás
    2020-09-19 22:50