Magnezium-szulfat intravénás adása után bekövetkező cardiorespiratoricus és elektrolit
változások status asthmaticusban [Cardiorespiratory and electrolytic changes in status
asthmaticus after intravenous administration of magnesium sulfate]
The authors studied cardiorespiratory effects of MgSO4 infusion in 30 randomized patients
with status asthmaticus. They found, that after having the drug administered, values
of VC, FEV1, FIV1, PaO2 and pH increased, the respiratory and heart rate, diastolic
blood pressure reduced. Other ventilation, blood gas and ECG parameters were unchanged.
Among the electrolytes, serum Ca2+ level has reduced, both plasma and intracellular
Mg2+ concentrations increased. It is apparent from the results, that broncholytical
ability of MgSO4 given in therapeutical dose i.v. does not reach the level of beta-stimulating
agents. However, this completed with the cardioprotective, sedative effect as well
as more advantageous ion-distribution, influences favourably the asthmatic dyspnoea.