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A cerebrovascularis reaktivitás vizsgálata inzulin dependens diabetes mellitusban acetazolamid-teszttel
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The aim of this study was to investigate, whether the cerebrovascular reactivity (CR) was altered in diabetes mellitus and to evaluate the influence of diabetes's duration on cerebrovascular reactivity. Transcranial Doppler-Acetazolamide tests were performed on 20 insulin-dependent diabetics and in 19 controls. Patients were divided into two groups, each group consisted of 10 patients: diabetics with > 10 years disease duration and with < 10 years diseases duration. Middle cerebral artery mean velocities were measured at rest and after i.v. administration of Ig Acetazolamide (AZ). There were no differences in the absolute velocities between controls and diabetics. The percentual increase of the mean velocity after AZ was slower and less intensive in longterm diabetics (means +/- SE: 5 min: 19.4 +/- 2.8%, 10 min: 28 +/- 3.6%, 15 min: 25.7 +/- 3.8%, 20 min: 23.9 +/- 4.3%), than that in controls (5 min: 32.3 +/- 4.3% -p < 0.05-, 10 min: 45.1 +/- 4.9% -p < 0.05-, 15 min: 47.5 +/- 4.3% -p < 0.01-, 20 min: 46.5 +/- 4.7% -p < 0.01) as well as in diabetics with < 10 years disease duration (5 min.: 39.5 +/- 7% -p < 0.05-, 10 min.: 49.2 +/- 6.5% -p < 0.05-, 15 min.: 53.9 +/- 8.6% -p < 0.01-, 20 min: 32.9 +/- 5.9% -n.s.). The cerebrovascular reactivity is impaired in diabetics after long duration of the disease. The altered cerebrovascular reactivity might be caused by angiopathy of the cerebral arterioles.
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<div class="JournalArticle Publication short-list"> <div class="authors"> <span class="author-name" mtid="10013888"> <a href="/gui2/?type=authors&mode=browse&sel=10013888" target="_blank">Fulesdi, B</a> </span> <span class="author-type"> </span> ; <span class="author-name" > Limburg, M </span> <span class="author-type"> </span> ; <span class="author-name" > Neuwirth, G </span> <span class="author-type"> </span> ; <span class="author-name" mtid="10037125"> <a href="/gui2/?type=authors&mode=browse&sel=10037125" target="_blank">Molnar, C</a> </span> <span class="author-type"> </span> ; <span class="author-name" mtid="10044515"> <a href="/gui2/?type=authors&mode=browse&sel=10044515" target="_blank">Valikovics, A</a> </span> <span class="author-type"> </span> ; <span class="author-name" mtid="10000492"> <a href="/gui2/?type=authors&mode=browse&sel=10000492" target="_blank">Csiba, L</a> </span> <span class="author-type"> </span> </div ><div class="title"><a href="/gui2/?mode=browse¶ms=publication;1262982" mtid="1262982" target="_blank">A cerebrovascularis reaktivitás vizsgálata inzulin dependens diabetes mellitusban acetazolamid-teszttel</a></div> <div class="pub-info"> <span class="journal-title">ORVOSI HETILAP</span> <span class="journal-volume">137</span> : <span class="journal-issue">39</span> <span class="page"> pp. 2137-2140. , 4 p. </span> <span class="year">(1996)</span> </div> <div class="pub-end"><div class="identifier-list"> <span class="identifiers"> <span class="id identifier oa_none" title="none"> <a style="color:black" title="8927362" target="_blank" href="http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db=PubMed&list_uids=8927362&dopt=Abstract"> PubMed </a> </span> </span> </div> <div class="short-pub-prop-list"> <span class="deleted-record">Zárolt</span> <span class="short-pub-mtid"> Közlemény:1262982 </span> <span class="status-holder"><span class="status-data status-ADMIN_APPROVED"> Admin láttamozott </span></span> <span class="pub-core">Forrás </span> <span class="pub-type">Folyóiratcikk (Szakcikk ) </span> <!-- && !record.category.scientific --> <span class="pub-category">Tudományos</span> <div class="publication-citation" style="margin-left: 0.5cm;"> <span title="Nyilvános idézőközlemények összesen, említések nélkül" class="citingPub-count">Nyilvános idéző összesen: 1</span> | Független: 1 | Függő: 0 | Nem jelölt: 0 | Scopus jelölt: 1 | WoS/Scopus jelölt: 1 | DOI jelölt: 1 </div> </div> </div> </div><div class="JournalArticle Publication long-list"> <div class="authors"> <img title="Forrásközlemény" style="float: left" src="/frontend/resources/grid/publication-core-icon.png"> <div class="autype autype0"> <span class="author-name" mtid="10013888"><a href="/gui2/?type=authors&mode=browse&sel=10013888" target="_blank">Fulesdi B (<span class="authorship-author-name">Fülesdi Béla</span> <span class="authorAux-mtmt"> Aneszteziológia és intenzív terápia</span>) </a> </span> <span class="author-affil"><span title="Debreceni Egyetem">DE</span>/<span title="Általános Orvostudományi Kar">ÁOK</span>/Aneszteziológiai és Intenzív Terápiás Tanszék</span> ; <span class="author-name" >Limburg M </span> ; <span class="author-name" >Neuwirth G </span> ; <span class="author-name" mtid="10037125"><a href="/gui2/?type=authors&mode=browse&sel=10037125" target="_blank">Molnar C (<span class="authorship-author-name">Molnár Csilla</span> <span class="authorAux-mtmt"> aneszteziológia-intenzív terápia</span>) </a> </span> <span class="author-affil"><span title="Debreceni Egyetem">DE</span>/<span title="Általános Orvostudományi Kar">ÁOK</span>/Aneszteziológiai és Intenzív Terápiás Tanszék</span> ; <span class="author-name" mtid="10044515"><a href="/gui2/?type=authors&mode=browse&sel=10044515" target="_blank">Valikovics A (<span class="authorship-author-name">Valikovics Attila</span> <span class="authorAux-mtmt"> Neurológia, pszichiátria</span>) </a> </span> ; <span class="author-name" mtid="10000492"><a href="/gui2/?type=authors&mode=browse&sel=10000492" target="_blank">Csiba L (<span class="authorship-author-name">Csiba László</span> <span class="authorAux-mtmt"> Neurológia</span>) </a> </span> <span class="author-affil"><span title="Debreceni Egyetem">DE</span>/<span title="Általános Orvostudományi Kar">ÁOK</span>/Neurológiai Tanszék</span> </div> </div> <div class="title"><a href="/gui2/?mode=browse¶ms=publication;1262982" target="_blank">A cerebrovascularis reaktivitás vizsgálata inzulin dependens diabetes mellitusban acetazolamid-teszttel</a></div> <div> <span class="journal-title">ORVOSI HETILAP</span> <span class="journal-issn">(<a target="_blank" href="https://portal.issn.org/resource/ISSN/0030-6002">0030-6002</a> <a target="_blank" href="https://portal.issn.org/resource/ISSN/1788-6120">1788-6120</a>)</span>: <span class="journal-volume">137</span> <span class="journal-issue">39</span> <span class="page"> pp 2137-2140 </span> <span class="year">(1996)</span> </div> <div class="pub-footer"> <span class="language" xmlns="http://www.w3.org/1999/html">Nyelv: Magyar | </span> <span class="identifiers"> <span class="id identifier oa_none" title="none"> <a style="color:black" title="8927362" target="_blank" href="http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db=PubMed&list_uids=8927362&dopt=Abstract"> PubMed </a> </span> </span> <div class="publication-citation" style="margin-left: 0.5cm;"> <span title="Nyilvános idézőközlemények összesen, említések nélkül" class="citingPub-count">Nyilvános idéző összesen: 1</span> | Független: 1 | Függő: 0 | Nem jelölt: 0 | Scopus jelölt: 1 | WoS/Scopus jelölt: 1 | DOI jelölt: 1 </div> <div class="mtid"><span class="long-pub-mtid">Közlemény: 1262982</span> | <span class="status-data status-ADMIN_APPROVED"> Admin láttamozott </span> <span class="oldId">Régi azonosító: 1262982</span> | Forrás | <span class="type-subtype">Folyóiratcikk ( Szakcikk ) </span> | <span class="pub-category">Tudományos</span> | <span class="publication-sourceOfData">kézi felvitel</span> </div> <div class="lastModified">Utolsó módosítás: 2018.09.12. 14:11 MTMT1 Admin (admin) </div> <div class="lockedBy">Ideiglenesen zárolva 2021.10.23. 03:09 MTMT API (MTMT API user, admin) Fölkerné Csernyik Rita (MTMT ellenőrzés admin5) </div> </div></div>