https://m2.mtmt.hu/ eng 2026-05-01 09:21 JournalArticle 1228374 VALIDATED true Export Date: 21 October 2025; 0 2016-01-12T12:40:00.000+0000 false 1228374 2025-12-19T22:07:40.193+0000 2025-10-21T09:17:05.474+0000 2009-04-19T22:00:00.000+0000 true 10002468 Érdi Péter /api/author/10002468 Author true 10002468 2025-10-21T09:18:43.877+0000 2022-10-21T07:48:08.981+0000 true 10083908 Verle Ilona /api/admin/10083908 Admin true true false true 24 24 /api/publicationtype/24 PublicationType 1 true 24 JournalArticle true 10000059 Article true 24 24 /api/publicationtype/24 PublicationType 1 true 24 JournalArticle /api/subtype/10000059 Szakcikk SubType 101 true 10000059 true 1 /api/category/1 Category true 1 Diwadkar, VA Impaired associative learning in schizophrenia: Behavioral and computational studies. true true /api/journal/10008952 REVIEWED true false 10008952 false 10008952 true 1871-4080 1871-4099 Journal FOREIGN 2 3 207 218 207 12 2008 Associative learning is a central building block of human cognition and in large part depends on mechanisms of synaptic plasticity, memory capacity and fronto-hippocampal interactions. A disorder like schizophrenia is thought to be characterized by altered plasticity, and impaired frontal and hippocampal function. Understanding the expression of this dysfunction through appropriate experimental studies, and understanding the processes that may give rise to impaired behavior through biologically plausible computational models will help clarify the nature of these deficits. We present a preliminary computational model designed to capture learning dynamics in healthy control and schizophrenia subjects. Experimental data was collected on a spatial-object paired-associate learning task. The task evinces classic patterns of negatively accelerated learning in both healthy control subjects and patients, with patients demonstrating lower rates of learning than controls. Our rudimentary computational model of the task was based on biologically plausible assumptions, including the separation of dorsal/spatial and ventral/object visual streams, implementation of rules of learning, the explicit parameterization of learning rates (a plausible surrogate for synaptic plasticity), and learning capacity (a plausible surrogate for memory capacity). Reductions in learning dynamics in schizophrenia were well-modeled by reductions in learning rate and learning capacity. The synergy between experimental research and a detailed computational model of performance provides a framework within which to infer plausible biological bases of impaired learning dynamics in schizophrenia. 2009 true true true false false NONE 2025-12-19 false true 10039656 Kmety Andrea /api/admin/10039656 Admin true 10039656 44 0 44 17 3 44 42 39 43 44 44 17 17 17 27 0 44 17 44 17 0 1 1 Folyóiratcikk Journal Article 24 38 Könyvrészlet Chapter in Book 25 6 Könyv Book 23 0 Egyéb konferenciaközlemény Conference paper 31 0 Egyéb konferenciakötet Conference proceedings 32 0 Oltalmi formák Protection forms 26 0 Disszertáció Thesis 28 0 Egyéb Miscellaneous 29 0 Alkotás Achievement 22 0 Kutatási adat Research data 33 0 Folyóiratcikk Journal Article 24 0 0 0 Könyvrészlet Chapter in Book 25 0 0 0 Könyv Book 23 0 0 0 Egyéb konferenciaközlemény Conference paper 31 0 0 0 Egyéb konferenciakötet Conference proceedings 32 0 0 0 Oltalmi formák Protection forms 26 0 0 0 Disszertáció Thesis 28 0 0 0 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false false AuthorshipType 1 /api/authorshiptype/1 0 true 0 true false 10739885 true PersonAuthorship 763020 /api/authorship/763020 4 0.14285715 false false Author 10017158 /api/author/10017158 Zalányi László András true 10017158 true Zalányi L true false false AuthorshipType 1 /api/authorshiptype/1 0 true 0 true false 10739884 true PersonAuthorship 763021 /api/authorship/763021 5 0.14285715 false false Author 10017153 /api/author/10017153 Ujfalussy Balázs Benedek true 10017153 true Ujfalussy B true false false AuthorshipType 1 /api/authorshiptype/1 0 true 0 true false 10739883 true PersonAuthorship 763022 /api/authorship/763022 6 0.14285715 false false Keshavan MS true false false AuthorshipType 1 /api/authorshiptype/1 0 true 0 true false 10739882 true PersonAuthorship 763023 /api/authorship/763023 7 0.143 false true true Author 10002468 /api/author/10002468 Érdi Péter true 10002468 true Érdi P true false false AuthorshipType 1 /api/authorshiptype/1 0 true 0 true false 10739881 true 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http://scholar.Google.com/scholar?hl=en&lr=&cluster=10919288530818011116 false 656836 true Classification 12125 /api/classification/12125 true true SjrRating 5857612 /api/sjrrating/5857612 46 1.0 journal RatingType 10002 /api/ratingtype/10002 sjr true true ClassificationExternal 2805 /api/classificationexternal/2805 true 2805 true Q4 DIRECT true 5857612 true /api/publication/1228374 <div class="JournalArticle Publication long-list"> <div class="authors"> <img title="Forrásközlemény" style="float: left" src="/frontend/resources/grid/publication-core-icon.png"> <img title="Idézőközlemény" style="float: left" src="/frontend/resources/grid/publication-citation-icon.png"> <div class="autype autype0"> <span class="author-name" >Diwadkar VA </span> ;&nbsp;&nbsp;&nbsp; <span class="author-name" >Flaugher B </span> ;&nbsp;&nbsp;&nbsp; <span class="author-name" >Jones T </span> ;&nbsp;&nbsp;&nbsp; <span class="author-name" mtid="10017158"><a href="/gui2/?type=authors&mode=browse&sel=10017158" target="_blank">Zalányi L (<span class="authorship-author-name">Zalányi László András</span> <span class="authorAux-mtmt"> Fizika, Elméleti idegtudomány</span>) </a> </span> <span class="author-affil"><span title="MTA KFKI Institute for Particle and Nuclear Physics">KFKI RMKI</span>/Biophysics</span> ;&nbsp;&nbsp;&nbsp; <span class="author-name" mtid="10017153"><a href="/gui2/?type=authors&mode=browse&sel=10017153" target="_blank">Ujfalussy B (<span class="authorship-author-name">Ujfalussy Balázs Benedek</span> <span class="authorAux-mtmt"> Idegtudományok</span>) </a> </span> <span class="author-affil"><span title="MTA KFKI Institute for Particle and Nuclear Physics">KFKI RMKI</span>/Biophysics</span> ;&nbsp;&nbsp;&nbsp; <span class="author-name" >Keshavan MS </span> ;&nbsp;&nbsp;&nbsp; <span class="author-name" mtid="10002468"><a href="/gui2/?type=authors&mode=browse&sel=10002468" target="_blank">Érdi P ✉ (<span class="authorship-author-name">Érdi Péter</span> <span class="authorAux-mtmt"> Fizikai kémia, matematikai modellek, elméleti n...</span>) </a> </span> <span class="author-affil"><span title="MTA KFKI Institute for Particle and Nuclear Physics">KFKI RMKI</span>/Biophysics</span> </div> </div> <div class="title"><a href="/gui2/?mode=browse&params=publication;1228374" target="_blank">Impaired associative learning in schizophrenia: Behavioral and computational studies.</a></div> <div> <span class="journal-title">COGNITIVE NEURODYNAMICS</span> <span class="journal-issn">(<a target="_blank" href="https://portal.issn.org/resource/ISSN/1871-4080">1871-4080</a> <a target="_blank" href="https://portal.issn.org/resource/ISSN/1871-4099">1871-4099</a>)</span>: <span class="journal-volume">2</span> <span class="journal-issue">3</span> <span class="page"> pp 207-218 </span> <span class="year">(2008)</span> </div> <div class="pub-footer"> <span class="language" xmlns="http://www.w3.org/1999/html">Language: English | </span> <span class="identifiers"> <span class="id identifier oa_none" title="none"> <a style="color:blue" title="10.1007/s11571-008-9054-0" target="_blank" href="https://doi.org/10.1007/s11571-008-9054-0"> DOI </a> </span> <span class="id identifier oa_none" title="none"> <a style="color:blue" title="000266413000004" target="_blank" href="https://www.webofscience.com/wos/woscc/full-record/000266413000004"> WoS </a> </span> <span class="id identifier oa_none" title="none"> <a style="color:blue" title="49249084242" target="_blank" href="http://www.scopus.com/record/display.url?origin=inward&eid=2-s2.0-49249084242"> Scopus </a> </span> <span class="id identifier oa_NONE" title=" None "> <a style="color:blue" title="https://www.scopus.com/inward/record.uri?eid=2-s2.0-49249084242&doi=10.1007%2Fs11571-008-9054-0&partnerID=40&md5=eb9a842e65846ce172589330307cc900" target="_blank" href="https://www.scopus.com/inward/record.uri?eid=2-s2.0-49249084242&doi=10.1007%2Fs11571-008-9054-0&partnerID=40&md5=eb9a842e65846ce172589330307cc900"> Other URL </a> </span> <span class="id identifier oa_none" title="none"> <a style="color:blue" title="10919288530818011116" target="_blank" href="http://scholar.Google.com/scholar?hl=en&lr=&cluster=10919288530818011116"> Google scholar </a> </span> </span> <OnlyViewableByAuthor><div class="ratings"> <div class="journal-subject">Journal subject: Scopus - Cognitive Neuroscience&nbsp;&nbsp;&nbsp;Rank:&nbsp;Q4</div> </div></OnlyViewableByAuthor> <div class="publication-citation" style="margin-left: 0.5cm;"> <span title="" class="citingPub-count">Citing papers: 44</span> | Independent citation: 17 | Self citation: 27 | Unknown citation: 0 | Number of citations in WoS: 39 | Number of citations in Scopus:&nbsp;43 | WoS/Scopus assigned:&nbsp;44 | Number of citations with DOI:&nbsp;42 </div> <div class="publication-citation"> <a target="_blank" href="/api/publication?cond=citations.related;eq;1228374&sort=publishedYear,desc&sort=title"> Number of cited publications: 1 </a> </div> <div class="mtid"><span class="long-pub-mtid">Publication: 1228374</span> | <span class="status-data status-VALIDATED"> Validated </span> <span class="oldId">Old id: 1228374</span> | Core Citing | <span class="type-subtype">Journal Article ( Article ) </span> | <span class="pub-category">Scientific</span> | <span class="publication-sourceOfData">kézi felvitel</span> </div> <div class="lastModified">Last Modified: 2025.10.21. 11:17 Adrienn Tomcsik (Wigner admin5) </div> <pre class="comment" style="margin-top: 0; margin-bottom: 0;"><u>Comments</u>: Export Date: 21 October 2025;</pre> </div></div>