New types of mass spectrometric instrumentation and new ionization techniques have
dramatically extended the applicability of mass spectrometry to the analysis of proteins
and peptides. In Mass Spectrometry of Proteins and Peptides, John R. Chapman recreates
the success of his earlier acclaimed book (Protein and Peptide Analysis by Mass Spectrometry,
1996) with a major new collection of cutting-edge methods in this area. Contributed
by well-established investigators, each chapter provides background information before
guiding the researcher step-by-step through the experimental process, with detailed
instructions to help assure experimental success. The applications covered range widely
and include protein sequencing, higher-order structure determination, epitope mapping,
kinetics, quantitation, glycosylation analysis, and bacterial typing.
Authoritative and eminently practical, Mass Spectrometry of Proteins and Peptides
demonstrates the full scope of this versatile analytical technique. All protein chemists
and biochemists, as well as bioanalytical scientists, who want to exploit these powerful
methods in their work, will find this book indispensable.
