https://m2.mtmt.hu/ hun 2026-05-01 15:26 JournalArticle 1204243 ADMIN_APPROVED true 0 2018-09-13T04:16:57.000+0000 false 1204243 2026-04-23T01:20:45.199+0000 2023-09-18T21:25:21.265+0000 2009-03-09T23:00:00.000+0000 true 10002122 Rácz Bence /api/author/10002122 Author Rácz Bence (Idegtudomány) true 10002122 2023-09-18T21:25:21.631+0000 2023-09-18T21:25:21.631+0000 2013-12-16T14:21:02.000+0000 true 10015468 Miszori Katalin /api/admin/10015468 Admin Miszori Katalin (könyvtáros, admin) true 10015468 Admin 10014568 /api/admin/10014568 Vándor Andrea (VA, admin) Vándor Andrea true 10014568 true 2022-11-11T11:59:57.718+0000 true false true 24 24 /api/publicationtype/24 PublicationType Folyóiratcikk 1 true 24 JournalArticle true 10000059 Article true 24 24 /api/publicationtype/24 PublicationType Folyóiratcikk 1 true 24 JournalArticle /api/subtype/10000059 Szakcikk SubType Szakcikk (Folyóiratcikk) 101 true 10000059 true 1 /api/category/1 Category Tudományos true 1 Lu, J true true /api/journal/3357 REVIEWED NEURON 0896-6273 1097-4199 true false 3357 false 3357 true 0896-6273 1097-4199 Journal FOREIGN 55 6 874 889 874 16 2007 Endocytosis; of AMPA receptors and other postsynaptic cargo occurs at endocytic zones (EZs), stably positioned sites of clathrin adjacent to the postsynaptic density (PSD). The tight localization of postsynaptic endocytosis is thought to control spine composition and regulate synaptic transmission. However, the mechanisms that situate the EZ near the PSD and the role of spine endocytosis in synaptic transmission are unknown. Here, we report that a physical link between dynamin-3 and the postsynaptic adaptor Homer positions the EZ near the PSD. Disruption of dynamin-3 or its interaction with Homer uncouples the PSD from the EZ, resulting in synapses lacking postsynaptic clathrin. Loss of the EZ leads to a loss of synaptic AMPA receptors and reduced excitatory synaptic transmission that corresponds with impaired synaptic recycling. Thus, a physical link between the PSD and the EZ ensures localized endocytosis and recycling by recapturing and maintaining a proximate pool of cycling AMPA receptors. 2009 true true true false true false NONE 2026-04-23 false 226 0 226 208 3 225 225 217 223 226 226 208 208 208 18 0 226 208 226 208 0 2 2 Folyóiratcikk Journal Article 24 219 Könyvrészlet Chapter in Book 25 7 Könyv Book 23 0 Egyéb konferenciaközlemény Conference paper 31 0 Egyéb konferenciakötet Conference proceedings 32 0 Oltalmi formák Protection forms 26 0 Disszertáció Thesis 28 0 Egyéb Miscellaneous 29 0 Alkotás Achievement 22 0 Kutatási adat Research data 33 0 Folyóiratcikk Journal Article 24 0 0 0 Könyvrészlet Chapter in Book 25 0 0 0 Könyv Book 23 0 0 0 Egyéb konferenciaközlemény Conference paper 31 0 0 0 Egyéb konferenciakötet Conference proceedings 32 0 0 0 Oltalmi formák Protection forms 26 0 0 0 Disszertáció Thesis 28 0 0 0 Egyéb Miscellaneous 29 0 0 0 Alkotás Achievement 22 0 0 0 Kutatási adat Research data 33 0 0 0 2007 0 3 3 3 3 2008 0 13 9 13 9 2009 0 18 16 18 16 2010 0 16 13 16 13 2011 0 24 22 24 22 2012 0 16 14 16 14 2013 0 19 17 19 17 2014 0 12 11 12 11 2015 0 17 16 17 16 2016 0 9 9 9 9 2017 0 8 8 8 8 2018 0 14 14 14 14 2019 0 8 7 8 7 2020 0 9 9 9 9 2021 0 13 13 13 13 2022 0 8 8 8 8 2023 0 8 8 8 8 2024 0 7 7 7 7 2025 0 4 4 4 4 D1 false false false false 2013-12-16T14:21:02.000+0000 2012-06-07T08:59:03.000+0000 Anatómiai és Szövettani Tanszék (SZIE / ÁOTK) 1 12 1 7 0 true 10014568 Language 10002 /api/language/10002 Angol Angol English true 2 true PersonAuthorship 725994 /api/authorship/725994 Lu, J 1 0.14285715 true false Lu J true false false AuthorshipType 1 /api/authorshiptype/1 Szerző 0 true 0 true false 10673902 true PersonAuthorship 725995 /api/authorship/725995 Helton, TD 2 0.14285715 false false Helton TD true false false AuthorshipType 1 /api/authorshiptype/1 Szerző 0 true 0 true false 10673901 true PersonAuthorship 725996 /api/authorship/725996 Blanpied, TA 3 0.14285715 false false Blanpied TA true false false AuthorshipType 1 /api/authorshiptype/1 Szerző 0 true 0 true false 10673900 true PersonAuthorship 725997 /api/authorship/725997 Racz, B [Rácz, Bence (Idegtudomány), szerző] Anatómiai és Szövettani Tanszék (SZIE / ÁOTK) 4 0.14285715 false false Author 10002122 /api/author/10002122 Rácz Bence (Idegtudomány) Rácz Bence true 10002122 true Racz B true false false AuthorshipType 1 /api/authorshiptype/1 Szerző 0 true 0 true false 10673899 true PersonAuthorship 725998 /api/authorship/725998 Newpher, TM 5 0.14285715 false false Newpher TM true false false AuthorshipType 1 /api/authorshiptype/1 Szerző 0 true 0 true false 10673898 true PersonAuthorship 725999 /api/authorship/725999 Weinberg, RJ 6 0.14285715 false false Weinberg RJ true false false AuthorshipType 1 /api/authorshiptype/1 Szerző 0 true 0 true false 10673897 true PersonAuthorship 726000 /api/authorship/726000 Ehlers, MD 7 0.14285715 false true Ehlers MD true false false AuthorshipType 1 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(2007) NEURON 0896-6273 1097-4199 55 6 874-889<div class="JournalArticle Publication long-list"> <div class="authors"> <img title="Forrásközlemény" style="float: left" src="/frontend/resources/grid/publication-core-icon.png"> <img title="Idézőközlemény" style="float: left" src="/frontend/resources/grid/publication-citation-icon.png"> <div class="autype autype0"> <span class="author-name" >Lu J </span> ;&nbsp;&nbsp;&nbsp; <span class="author-name" >Helton TD </span> ;&nbsp;&nbsp;&nbsp; <span class="author-name" >Blanpied TA </span> ;&nbsp;&nbsp;&nbsp; <span class="author-name" mtid="10002122"><a href="/gui2/?type=authors&mode=browse&sel=10002122" target="_blank">Racz B (<span class="authorship-author-name">Rácz Bence</span> <span class="authorAux-mtmt"> Idegtudomány</span>) </a> </span> <span class="author-affil"><span title="Szent István Egyetem">SZIE</span>/<span title="Állatorvostudományi Kar">ÁOTK</span>/Anatómiai és Szövettani Tanszék</span> ;&nbsp;&nbsp;&nbsp; <span class="author-name" >Newpher TM </span> ;&nbsp;&nbsp;&nbsp; <span class="author-name" >Weinberg RJ </span> ;&nbsp;&nbsp;&nbsp; <span class="author-name" >Ehlers MD </span> </div> </div> <div class="title"><a href="/gui2/?mode=browse&params=publication;1204243" target="_blank">Postsynaptic positioning of endocytic zones and AMPA receptor cycling by physical coupling of dynamin-3 to homer</a></div> <div> <span class="journal-title">NEURON</span> <span class="journal-issn">(<a target="_blank" href="https://portal.issn.org/resource/ISSN/0896-6273">0896-6273</a> <a target="_blank" href="https://portal.issn.org/resource/ISSN/1097-4199">1097-4199</a>)</span>: <span class="journal-volume">55</span> <span class="journal-issue">6</span> <span class="page"> pp 874-889 </span> <span class="year">(2007)</span> </div> <div class="pub-footer"> <span class="language" xmlns="http://www.w3.org/1999/html">Nyelv: Angol | </span> <span class="identifiers"> <span class="id identifier oa_none" title="none"> <a style="color:blue" title="10.1016/j.neuron.2007.06.041" target="_blank" href="https://doi.org/10.1016/j.neuron.2007.06.041"> DOI </a> </span> <span class="id identifier oa_none" title="none"> <a style="color:blue" title="000250078500006" target="_blank" href="https://www.webofscience.com/wos/woscc/full-record/000250078500006"> WoS </a> </span> <span class="id identifier oa_none" title="none"> <a style="color:black" title="34548555643" target="_blank" href="http://www.scopus.com/record/display.url?origin=inward&eid=2-s2.0-34548555643"> Scopus </a> </span> <span class="id identifier oa_none" title="none"> <a style="color:blue" title="17880892" target="_blank" href="http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db=PubMed&list_uids=17880892&dopt=Abstract"> PubMed </a> </span> </span> <OnlyViewableByAuthor><div class="ratings"> <div class="journal-subject">Folyóirat szakterülete: Scopus - Neuroscience (miscellaneous)&nbsp;&nbsp;&nbsp;SJR indikátor:&nbsp;D1</div> </div></OnlyViewableByAuthor> <div class="publication-citation" style="margin-left: 0.5cm;"> <span title="Nyilvános idézőközlemények összesen, említések nélkül" class="citingPub-count">Nyilvános idéző összesen: 226</span> | Független: 208 | Függő: 18 | Nem jelölt: 0 | WoS jelölt: 217 | Scopus jelölt:&nbsp;223 | WoS/Scopus jelölt:&nbsp;226 | DOI jelölt:&nbsp;225 </div> <div class="publication-citation"> <a target="_blank" href="/api/publication?cond=citations.related;eq;1204243&sort=publishedYear,desc&sort=title"> Idézett közlemények száma: 2 </a> </div> <div class="mtid"><span class="long-pub-mtid">Közlemény: 1204243</span> | <span class="status-data status-ADMIN_APPROVED"> Admin láttamozott </span> <span class="oldId">Régi azonosító: 1204243</span> | Forrás Idéző | <span class="type-subtype">Folyóiratcikk ( Szakcikk ) </span> | <span class="pub-category">Tudományos</span> | <span class="publication-sourceOfData">kézi felvitel</span> </div> <div class="lastModified">Utolsó módosítás: 2023.09.18. 23:25 Ladányi Gusztáv (MTMT API user, admin) </div> <div class="lockedBy">Központi kezelésű 2022.11.11. 12:59 Vándor Andrea (VA, admin) </div> </div></div>