https://m2.mtmt.hu/ hun 2026-10-24 16:24 JournalArticle 1163352 ADMIN_APPROVED true : FN Thomson Reuters Web of Knowledge Z9: 22 WC: Chemistry, Organic 0 2014-08-14T19:28:36.000+0000 false 1163352 2026-10-13T17:39:42.736+0000 2020-12-17T09:10:51.397+0000 2009-01-22T23:00:00.000+0000 true 10010042 Kovács Lajos /api/author/10010042 Author true 10010042 2021-02-09T09:29:22.821+0000 2021-02-09T09:29:22.821+0000 2020-05-26T20:08:55.026+0000 true 10036259 Zékány László /api/admin/10036259 Admin true 10036259 true false true 24 24 /api/publicationtype/24 PublicationType 1 true 24 JournalArticle true 10000059 Article true 24 24 /api/publicationtype/24 PublicationType 1 true 24 JournalArticle /api/subtype/10000059 Szakcikk SubType 101 true 10000059 true 1 /api/category/1 Category true 1 L, Kovács Thiazole c-nucleosides .3. Synthesis of pyranose analogs of tiazofurin true true /api/journal/4246 REVIEWED true false 4246 false 4246 true 0040-4020 1464-5416 Journal FOREIGN 47 29 5539 5548 5539 10 1991 A large-scale synthesis of 3,4,5-tri-0-acetyl-2,6-anhydro-L-mannono-and-D-gulonothioamides (5, 6) has been achieved from the corresponding nitriles. The Hantzsch reaction of (5) or (6) with ethyl bromopyruvate afforded the expected thiazoles (7.8) only in a low yield along with furan derivatives (9-11), the formation of which is rationalized by an acid-catalysed rearrangement-elimination process. The some Hantzsch reaction in the presence of barium carbonate yielded hydroxythiazolines (16,17). Attempted dehydration of (16) or (17) with trifluoroacetic anhydride or trifluoroacetic anhydride/pyridine resulted in the formation of pent-1′-enopyranosylthiazoles (18-20). Deprotected thioamides (24,25) furnished with ethyl bromopyruvate thiazoles (27,28). The obtained thiazole esters (7,8, 18-20. 27,28) were transformed into new tiazofurin analogues (12, 13, 21- 23). New tiazofurin analogues (1-5) have been synthesized starting from the corresponding thioamides. 2009 true true true false true false NONE 2026-10-13 false 35 0 33 29 10 32 17 27 28 30 30 26 26 31 4 0 35 31 33 29 0 1 1 Folyóiratcikk Journal Article 24 26 Könyvrészlet Chapter in Book 25 7 Könyv Book 23 0 Egyéb konferenciaközlemény Conference paper 31 0 Egyéb konferenciakötet Conference proceedings 32 0 Oltalmi formák Protection forms 26 0 Disszertáció Thesis 28 2 Egyéb Miscellaneous 29 0 Alkotás Achievement 22 0 Kutatási adat Research data 33 0 Folyóiratcikk Journal Article 24 0 0 0 Könyvrészlet Chapter in Book 25 0 0 0 Könyv Book 23 0 0 0 Egyéb konferenciaközlemény Conference paper 31 0 0 0 Egyéb konferenciakötet Conference proceedings 32 0 0 0 Oltalmi formák Protection forms 26 0 0 0 Disszertáció Thesis 28 0 0 0 Egyéb Miscellaneous 29 0 0 0 Alkotás Achievement 22 0 0 0 Kutatási adat Research data 33 0 0 0 1992 0 2 2 2 2 1993 0 2 1 2 1 1994 0 4 3 4 3 1995 0 4 3 4 3 1996 0 3 3 3 3 1997 0 1 1 1 1 1998 0 1 1 1 1 1999 0 4 3 4 3 2000 0 1 1 1 1 2001 0 1 1 1 1 2002 0 1 1 1 1 2003 0 1 1 1 1 2004 0 0 0 0 0 2005 0 0 0 0 0 2006 0 0 0 0 0 2007 0 0 0 0 0 2008 0 0 0 0 0 2009 0 0 0 0 0 2010 0 0 0 0 0 2011 0 2 2 2 2 2012 0 1 1 1 1 2013 0 0 0 0 0 2014 0 1 1 1 1 2015 0 2 2 2 2 2016 0 0 0 0 0 2017 0 1 1 1 1 2018 0 1 1 1 1 2019 0 0 0 0 0 2020 0 1 1 1 1 2021 0 0 0 0 0 2022 0 0 0 0 0 2023 0 0 0 0 0 2024 0 1 1 1 1 false false false false 2013-05-24T18:18:00.000+0000 2013-02-23T19:18:00.000+0000 MTA-DE Antibiotikum-kémiai Kutatócsoport (2006 ... (MTA TKI); Szerves Kémiai Tanszék (DE / TEK / TTK / KemI) 3 34 2 4 0 true Language 10002 /api/language/10002 Angol English true 2 true PersonAuthorship 652520 /api/authorship/652520 1 0.25 true false true Author 10010042 /api/author/10010042 Kovács Lajos true 10010042 true L Kovács true false false AuthorshipType 1 /api/authorshiptype/1 0 true 0 true false 10566031 true PersonAuthorship 652521 /api/authorship/652521 2 0.25 false false true Author 10001683 /api/author/10001683 Herczegh Pál true 10001683 true P Herczegh true false false AuthorshipType 1 /api/authorshiptype/1 0 true 0 true false 10566030 true PersonAuthorship 652522 /api/authorship/652522 3 0.25 false false false Author 10007156 /api/author/10007156 Batta Gyula true 10007156 true Gy Batta true false false AuthorshipType 1 /api/authorshiptype/1 0 true 0 true false 10566029 true PersonAuthorship 652523 /api/authorship/652523 4 0.25 false true false I Farkas true false false AuthorshipType 1 /api/authorshiptype/1 0 true 0 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Reference 1000823 /api/reference/1000823 32 false true Reference 1000824 /api/reference/1000824 33 false true Reference 1000825 /api/reference/1000825 34 false true Reference 1000826 /api/reference/1000826 35 false true Reference 1000827 /api/reference/1000827 36 false true /api/publication/1163352 <div class="JournalArticle Publication long-list"> <div class="authors"> <img title="Forrásközlemény" style="float: left" src="/frontend/resources/grid/publication-core-icon.png"> <img title="Idézőközlemény" style="float: left" src="/frontend/resources/grid/publication-citation-icon.png"> <div class="autype autype0"> <span class="author-name" mtid="10010042"><a href="/gui2/?type=authors&mode=browse&sel=10010042" target="_blank">L Kovács ✉ (<span class="authorship-author-name">Kovács Lajos</span> <span class="authorAux-mtmt"> Nukleinsavak</span>) </a> </span> <span class="author-affil"><span title="Debreceni Egyetem">DE</span>/<span title="Tudományegyetemi Karok">TEK</span>/<span title="Természettudományi és Technológiai Kar">TTK</span>/<span title="Kémiai Intézet">KemI</span>/Szerves Kémiai Tanszék</span> ;&nbsp;&nbsp;&nbsp; <span class="author-name" mtid="10001683"><a href="/gui2/?type=authors&mode=browse&sel=10001683" target="_blank">P Herczegh ✉ (<span class="authorship-author-name">Herczegh Pál</span> <span class="authorAux-mtmt"> Szerves kémia</span>) </a> </span> <span class="author-affil"><span title="MTA Támogatott Kutatócsoportok">MTA TKI</span>/MTA-DE Antibiotikum-kémiai Kutatócsoport (2006 végéig működött)</span> ;&nbsp;&nbsp;&nbsp; <span class="author-name" mtid="10007156"><a href="/gui2/?type=authors&mode=browse&sel=10007156" target="_blank">Gy Batta (<span class="authorship-author-name">Batta Gyula</span> <span class="authorAux-mtmt"> NMR spektroszkópia</span>) </a> </span> <span class="author-affil"><span title="MTA Támogatott Kutatócsoportok">MTA TKI</span>/MTA-DE Antibiotikum-kémiai Kutatócsoport (2006 végéig működött)</span> ;&nbsp;&nbsp;&nbsp; <span class="author-name" >I Farkas </span> </div> </div> <div class="title"><a href="/gui2/?mode=browse&params=publication;1163352" target="_blank">Thiazole c-nucleosides .3. Synthesis of pyranose analogs of tiazofurin</a></div> <div> <span class="journal-title">TETRAHEDRON</span> <span class="journal-issn">(<a target="_blank" href="https://portal.issn.org/resource/ISSN/0040-4020">0040-4020</a> <a target="_blank" href="https://portal.issn.org/resource/ISSN/1464-5416">1464-5416</a>)</span>: <span class="journal-volume">47</span> <span class="journal-issue">29</span> <span class="page"> pp 5539-5548 </span> <span class="year">(1991)</span> </div> <div class="pub-footer"> <span class="language" xmlns="http://www.w3.org/1999/html">Nyelv: Angol | </span> <span class="identifiers"> <span class="id identifier oa_none" title="none"> <a style="color:black" title="10.1016/S0040-4020(01)80985-6" target="_blank" href="https://doi.org/10.1016/S0040-4020%2801%2980985-6"> DOI </a> </span> <span class="id identifier oa_none" title="none"> <a style="color:blue" title="A1991FW67300016" target="_blank" href="https://www.webofscience.com/wos/woscc/full-record/A1991FW67300016"> WoS </a> </span> <span class="id identifier oa_none" title="none"> <a style="color:black" title="0025745066" target="_blank" href="http://www.scopus.com/record/display.url?origin=inward&eid=2-s2.0-0025745066"> Scopus </a> </span> </span> <div class="publication-citation" style="margin-left: 0.5cm;"> <span title="Nyilvános idézőközlemények összesen, említések nélkül" class="citingPub-count">Nyilvános idéző összesen: 35</span> | Független: 31 | Függő: 4 | Nem jelölt: 0 | WoS jelölt: 27 | Scopus jelölt:&nbsp;28 | WoS/Scopus jelölt:&nbsp;30 | DOI jelölt:&nbsp;17 </div> <div class="publication-citation"> <a target="_blank" href="/api/publication?cond=citations.related;eq;1163352&sort=publishedYear,desc&sort=title"> Idézett közlemények száma: 1 </a> </div> <div class="mtid"><span class="long-pub-mtid">Közlemény: 1163352</span> | <span class="status-data status-ADMIN_APPROVED"> Admin láttamozott </span> <span class="oldId">Régi azonosító: 1163352</span> | Forrás Idéző | <span class="type-subtype">Folyóiratcikk ( Szakcikk ) </span> | <span class="pub-category">Tudományos</span> | <span class="publication-sourceOfData">kézi felvitel</span> </div> <div class="lastModified">Utolsó módosítás: 2020.12.17. 10:10 Szuper Admin (admin) </div> <pre class="comment" style="margin-top: 0; margin-bottom: 0;"><u>Megjegyzés</u>: : FN Thomson Reuters Web of Knowledge Z9: 22 WC: Chemistry, Organic</pre> </div></div>