The wide-spread presence of adenoviruses in various species makes it
probable that carrier state and infection also exist in cats.
On the basis of the above consideration the authors began to
investigate the presence of antibodies against adenovirus in sera
originating from live and dead cats kept under different conditions.
Antibody detection was done by indirect and competitive ELISA and
agar-gel precipitation. Purified human adenovirus hexon was employed as
antigen, which has common antigen determinant in most adenoviruses.
Serum of SPF experimental cats immunized with adenovirus hexon antigen
was used as positive control in the serological tests.
Field sera/plasmas of 294 Hungarian, 102 Scottish and 64 Dutch cats,
and 10 serum samples of Italian experimental cats were tested.
Seropositivity was found in 15%, 20% and 10% of the field samples,
respectively. It is interesting that the 10 experimental cats showed
marked elevation in infection extensivity (50%).
The authors think that these results reflect on the natural infection
of the feline population(s), and these findings are similar to those
found in humans and other species.
Currently an attempt for adenovirus isolation from feline samples has
been in progress.