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      <abstractText>In this study, the physiological effect of the chicory extract was investigated in a short-term animal experiment in two different dietary animal groups. Male Wistar rats (150 - 200 g) were fed with a normal diet, and another group with a fat-rich diet (2% cholesterol, 0.5% cholic acid and 20% sunflower oil added to the basic diet) for 10 days.
In each group, 10 animals were treated ad libitum with chicory extract (daily 2 g/bw/kg) parallel with the basic feedings. Histologic examinations were performed to evaluate the tissue alterations in the liver. Serum cholesterol and triacylglycerol concentrations changed parallel with the tissue degradation. The concentration of blood glucose was enhanced in both chicory-treated groups. Element concentrations of the chicory extract and liver homogenates were determined by ICP-OES. Upon treatment with chicory, the differences between the mean concentration values of Ca, Cu, Fe, K, Na, P and Zn in, the liver homogenate of rats on the normal diet were significant.
It was well-detected that the mean concentration values of Cr, Fe, K, Na, P and S in the liver homogenate of rats on the lipid-rich diet increased significantly. In the chicory supplemented lipid-rich dietary group, due to metal ion accumulation, some slight decrease could be detected in the diene conjugate content of the liver. Only moderate elevation was determined in the concentration of the free SH groups or
in the value of reducing power of the liver tissue of rats in this short-term experiment. Consequently, more attention should be paid to the metal element and the oligosaccharide content of Cichorium intybus (L.) which may decrease the beneficial effect of the antioxidant compounds of the plant on the redox balance, and may contribute to the impairment of lipid and carbohydrate metabolism in the fatty liver.</abstractText>
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&lt;div class=&quot;autype autype0&quot;&gt; &lt;span class=&quot;author-name&quot; &gt;Kocsis I &lt;/span&gt; ;&amp;nbsp;&amp;nbsp;&amp;nbsp; &lt;span class=&quot;author-name&quot; mtid=&quot;10002938&quot;&gt;&lt;a href=&quot;/gui2/?type=authors&amp;mode=browse&amp;sel=10002938&quot; target=&quot;_blank&quot;&gt;Szentmihalyi K (&lt;span class=&quot;authorship-author-name&quot;&gt;Szentmihályi Klára&lt;/span&gt; &lt;span class=&quot;authorAux-mtmt&quot;&gt; Élelmiszertudomány&lt;/span&gt;) &lt;/a&gt; &lt;/span&gt; &lt;span class=&quot;author-affil&quot;&gt;&lt;span title=&quot;MTA Kémiai Kutatóközpont&quot;&gt;MTA KK&lt;/span&gt;/Anyag- és Környezetkémiai Intézet&lt;/span&gt; ;&amp;nbsp;&amp;nbsp;&amp;nbsp; &lt;span class=&quot;author-name&quot; &gt;Rapavi E &lt;/span&gt; ;&amp;nbsp;&amp;nbsp;&amp;nbsp; &lt;span class=&quot;author-name&quot; mtid=&quot;10025834&quot;&gt;&lt;a href=&quot;/gui2/?type=authors&amp;mode=browse&amp;sel=10025834&quot; target=&quot;_blank&quot;&gt;Hubay M (&lt;span class=&quot;authorship-author-name&quot;&gt;Hubay Márta&lt;/span&gt; &lt;span class=&quot;authorAux-mtmt&quot;&gt; igazságügyi orvostan&lt;/span&gt;) &lt;/a&gt; &lt;/span&gt; &lt;span class=&quot;author-affil&quot;&gt;&lt;span title=&quot;Semmelweis Egyetem&quot;&gt;SE&lt;/span&gt;/&lt;span title=&quot;Általános Orvostudományi Kar&quot;&gt;AOK&lt;/span&gt;/&lt;span title=&quot;Intézet&quot;&gt;I&lt;/span&gt;/Igazságügyi és Biztosítás-orvostani Intézet&lt;/span&gt; ;&amp;nbsp;&amp;nbsp;&amp;nbsp; &lt;span class=&quot;author-name&quot; mtid=&quot;10010049&quot;&gt;&lt;a href=&quot;/gui2/?type=authors&amp;mode=browse&amp;sel=10010049&quot; target=&quot;_blank&quot;&gt;Kery A (&lt;span class=&quot;authorship-author-name&quot;&gt;Kéry Ágnes&lt;/span&gt; &lt;span class=&quot;authorAux-mtmt&quot;&gt; Fitokémia, fitoterápia&lt;/span&gt;) &lt;/a&gt; &lt;/span&gt; &lt;span class=&quot;author-affil&quot;&gt;&lt;span title=&quot;Semmelweis Egyetem&quot;&gt;SE&lt;/span&gt;/&lt;span title=&quot;Gyógyszerésztudományi Kar&quot;&gt;GYTK&lt;/span&gt;/Farmakognóziai Intézet&lt;/span&gt; ;&amp;nbsp;&amp;nbsp;&amp;nbsp; &lt;span class=&quot;author-name&quot; mtid=&quot;10010023&quot;&gt;&lt;a href=&quot;/gui2/?type=authors&amp;mode=browse&amp;sel=10010023&quot; target=&quot;_blank&quot;&gt;Stefanovits-Banyai E (&lt;span class=&quot;authorship-author-name&quot;&gt;Stefanovitsné Bányai Éva&lt;/span&gt; &lt;span class=&quot;authorAux-mtmt&quot;&gt; Kertészeti növények antioxidáns kapacitása&lt;/span&gt;) &lt;/a&gt; &lt;/span&gt; &lt;span class=&quot;author-affil&quot;&gt;&lt;span title=&quot;Budapesti Corvinus Egyetem&quot;&gt;BCE&lt;/span&gt;/&lt;span title=&quot;Élelmiszertudományi Kar&quot;&gt;ÉTK&lt;/span&gt;/Alkalmazott Kémia Tanszék&lt;/span&gt; ;&amp;nbsp;&amp;nbsp;&amp;nbsp; &lt;span class=&quot;author-name&quot; mtid=&quot;10001352&quot;&gt;&lt;a href=&quot;/gui2/?type=authors&amp;mode=browse&amp;sel=10001352&quot; target=&quot;_blank&quot;&gt;Szoke E (&lt;span class=&quot;authorship-author-name&quot;&gt;Szőke Éva&lt;/span&gt; &lt;span class=&quot;authorAux-mtmt&quot;&gt; Farmakognózia, biotechnológia&lt;/span&gt;) &lt;/a&gt; &lt;/span&gt; &lt;span class=&quot;author-affil&quot;&gt;&lt;span title=&quot;Semmelweis Egyetem&quot;&gt;SE&lt;/span&gt;/&lt;span title=&quot;Gyógyszerésztudományi Kar&quot;&gt;GYTK&lt;/span&gt;/Farmakognóziai Intézet&lt;/span&gt; ;&amp;nbsp;&amp;nbsp;&amp;nbsp; &lt;span class=&quot;author-name&quot; mtid=&quot;10015320&quot;&gt;&lt;a href=&quot;/gui2/?type=authors&amp;mode=browse&amp;sel=10015320&quot; target=&quot;_blank&quot;&gt;Blazovics A (&lt;span class=&quot;authorship-author-name&quot;&gt;Blázovics Anna&lt;/span&gt; &lt;span class=&quot;authorAux-mtmt&quot;&gt; Hepatológiai és gastroenterológiai kutatások&lt;/span&gt;) &lt;/a&gt; &lt;/span&gt; &lt;span class=&quot;author-affil&quot;&gt;&lt;span title=&quot;Semmelweis Egyetem&quot;&gt;SE&lt;/span&gt;/&lt;span title=&quot;Általános Orvostudományi Kar&quot;&gt;AOK&lt;/span&gt;/&lt;span title=&quot;Klinikum&quot;&gt;K&lt;/span&gt;/II. Sz. Belgyógyászati Klinika&lt;/span&gt; &lt;/div&gt; &lt;/div&gt; &lt;div class=&quot;title&quot;&gt;&lt;a href=&quot;/gui2/?mode=browse&amp;params=publication;1131335&quot; target=&quot;_blank&quot;&gt;Effect of cichorium intybus (L.) extract on the redox balance and metal ion content of fatty liver in hyperlipidemic rats&lt;/a&gt;&lt;/div&gt; &lt;div&gt; &lt;span class=&quot;journal-title&quot;&gt;TRACE ELEMENTS AND ELECTROLYTES&lt;/span&gt; &lt;span class=&quot;journal-issn&quot;&gt;(&lt;a target=&quot;_blank&quot; href=&quot;https://portal.issn.org/resource/ISSN/0946-2104&quot;&gt;0946-2104&lt;/a&gt; &lt;a target=&quot;_blank&quot; href=&quot;https://portal.issn.org/resource/ISSN/0946-2104&quot;&gt;0946-2104&lt;/a&gt;)&lt;/span&gt;: &lt;span class=&quot;journal-volume&quot;&gt;21&lt;/span&gt; &lt;span class=&quot;journal-issue&quot;&gt;4&lt;/span&gt; &lt;span class=&quot;page&quot;&gt; pp 262-268 &lt;/span&gt; &lt;span class=&quot;year&quot;&gt;(2004)&lt;/span&gt; &lt;/div&gt; &lt;div class=&quot;pub-footer&quot;&gt;  &lt;span class=&quot;language&quot; xmlns=&quot;http://www.w3.org/1999/html&quot;&gt;Nyelv: Angol | &lt;/span&gt; &lt;span class=&quot;identifiers&quot;&gt; &lt;span class=&quot;id identifier oa_none&quot; title=&quot;none&quot;&gt; &lt;a style=&quot;color:blue&quot; title=&quot;10.5414/tep21262&quot; target=&quot;_blank&quot; href=&quot;https://doi.org/10.5414/tep21262&quot;&gt; DOI &lt;/a&gt; &lt;/span&gt; &lt;span class=&quot;id identifier oa_none&quot; title=&quot;none&quot;&gt; &lt;a style=&quot;color:blue&quot; title=&quot;000224956800012&quot; target=&quot;_blank&quot; href=&quot;https://www.webofscience.com/wos/woscc/full-record/000224956800012&quot;&gt; WoS &lt;/a&gt; &lt;/span&gt; &lt;span class=&quot;id identifier oa_none&quot; title=&quot;none&quot;&gt; &lt;a style=&quot;color:blue&quot; title=&quot;7444233208&quot; target=&quot;_blank&quot; href=&quot;http://www.scopus.com/record/display.url?origin=inward&amp;eid=2-s2.0-7444233208&quot;&gt; Scopus &lt;/a&gt; &lt;/span&gt; &lt;/span&gt; &lt;OnlyViewableByAuthor&gt;&lt;div class=&quot;ratings&quot;&gt; &lt;div class=&quot;journal-subject&quot;&gt;Folyóirat szakterülete: Scopus - Biochemistry&amp;nbsp;&amp;nbsp;&amp;nbsp;SJR indikátor:&amp;nbsp;Q3&lt;/div&gt; &lt;div class=&quot;journal-subject&quot;&gt;Folyóirat szakterülete: Scopus - Clinical Biochemistry&amp;nbsp;&amp;nbsp;&amp;nbsp;SJR indikátor:&amp;nbsp;Q3&lt;/div&gt; &lt;div class=&quot;journal-subject&quot;&gt;Folyóirat szakterülete: Scopus - Inorganic Chemistry&amp;nbsp;&amp;nbsp;&amp;nbsp;SJR indikátor:&amp;nbsp;Q3&lt;/div&gt; &lt;/div&gt;&lt;/OnlyViewableByAuthor&gt; &lt;div class=&quot;publication-citation&quot; style=&quot;margin-left: 0.5cm;&quot;&gt; &lt;span title=&quot;Nyilvános idézőközlemények összesen, említések nélkül&quot; class=&quot;citingPub-count&quot;&gt;Nyilvános idéző összesen: 6&lt;/span&gt; | Független: 1 | Függő: 5 | Nem jelölt: 0 | WoS jelölt: 2 | Scopus jelölt:&amp;nbsp;4 | WoS/Scopus jelölt:&amp;nbsp;4 | DOI jelölt:&amp;nbsp;3 &lt;/div&gt;   &lt;div class=&quot;publication-citation&quot;&gt; &lt;a target=&quot;_blank&quot; href=&quot;/api/publication?cond=citations.related;eq;1131335&amp;sort=publishedYear,desc&amp;sort=title&quot;&gt; Idézett közlemények száma: 3 &lt;/a&gt; &lt;/div&gt; &lt;div class=&quot;mtid&quot;&gt;&lt;span class=&quot;long-pub-mtid&quot;&gt;Közlemény: 1131335&lt;/span&gt; | &lt;span class=&quot;status-data status-VALIDATED&quot;&gt; Egyeztetett &lt;/span&gt; &lt;span class=&quot;oldId&quot;&gt;Régi azonosító: 1131335&lt;/span&gt; | Forrás Idéző | &lt;span class=&quot;type-subtype&quot;&gt;Folyóiratcikk ( Szakcikk ) &lt;/span&gt; | &lt;span class=&quot;pub-category&quot;&gt;Tudományos&lt;/span&gt; | &lt;span class=&quot;publication-sourceOfData&quot;&gt;WOS&lt;/span&gt; &lt;/div&gt; &lt;div class=&quot;lastModified&quot;&gt;Utolsó módosítás: 2023.12.08. 20:09 Ladányi Gusztáv (MTMT API user, admin) &lt;/div&gt; &lt;/div&gt;&lt;/div&gt;</template2>
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