ModLoop is a web server for automated modeling of loops in protein
structures. The input is the atomic coordinates of the protein
structure in the Protein Data Bank format, and the specification of the
starting and ending residues of one or more segments to be modeled,
containing no more than 20 residues in total. The output is the
coordinates of the non-hydrogen atoms in the modeled segments. A user
provides the input to the server via a simple web interface, and
receives the output by e-mail. The server relies on the loop modeling
routine in MODELLER that predicts the loop conformations by
satisfaction of spatial restraints, without relying on a database of
known protein structures. For a rapid response, ModLoop runs on a
cluster of Linux PC computers.
