Az agyi rezisztenciaerek rezervkapacitásának meghatározása acetazolamid teszt során
végzett transcranialis Doppler és SPECT vizsgálattal [Determination of the cerebrovascular
reserve capacity by using acetazolamide as well as transcranial Doppler and SPECT
The aim of this study was the development of a simple bedside test to assess cerebrovascular
reserve capacity using transcranial Doppler sonography. We tried to validate the increase
in blood flow velocity as cerebrovascular reserve capacity in 20 (3 normal, 7 TIA,
10 completed stroke) patients. They were studied using transcranial Doppler sonography
and rCBF SPECT before and after injection of 1 g acetazolamide. Their increases in
blood flow velocity and changes in cerebral blood flow correlated significantly in
the symptomatic hemispheres (p less than 0.001). Blood flow velocity between the two
hemispheres (symptomatic and asymptomatic) was not significantly different at rest.
We offer these simple and reliable methods in clinical studies to clarify the frequency
of ischemic stroke of hemodynamic origin.