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The EIR inhibits the metabolic activity of infiltrated bacteria and the leaf tissue remains symptomless whereas HR also inhibits bacteria, but the leaf tissue shows confluent necrosis or necrosis of individual plant cells, depending on the inoculum concentration. After infiltration of a heterologous strain the rapid development of HR usually masks the effects of EIR which is developing at the same time. The aim of this study was to characterize the conditions in which EIR occurs in the absence of HR following the infiltration of heterologous pathovars of Pseudomonas syringae pathovars. A study was made of numerous experimental interactions of heterologous bacteria/tobacco leaves in which the HR induction time of the bacteria and/or the EIR response of the plant were modified. 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